Abstract:
Objective:It is sometimes difficult to obtain complete/partial response of large hepatocellular carcinoma (HCC) nodules by trans-arterial chemoembolization/embolization (TACE/TAE). The aim is retrospective investigation of tumor response of large HCC nodules (>7 cm) treated by the new TACE technique, repeated alternate infusion of cisplatin solution, and sparse gelatin slurry under balloon occlusion (RAIB-TACE). Materials and Methods. A microballoon catheter was placed at a proximal portion of the hepatic artery (subsegmental to the lobar level hepatic artery), and alternate infusion of cisplatin solution and sparse gelatin slurry were repeated under balloon occlusion until stasis of gelatin slurry beyond the catheter was seen. RAIB-TACE of multiple proximal hepatic and extrahepatic collateral arteries were performed to treat hemi-lobe or more of the liver while avoiding infusion into gastric and cystic arteries for 19 large nodules (>7 cm) in 19 patients without portal venous invasion. All patients underwent dynamic CT/MRI 1-3 months after RAIB-TACE, and tumor response of each large nodule was evaluated based on modified RECIST criteria. Results:CR, PR, SD, and PD were achieved in 11, 8, 0, and 0 nodules, respectively. CR and PR were considered as success, and the ratio of success was 100%. Major complications were abscess formation in the necrotic nodule (n = 1) which was treated by drainage tube placement, and subsegmental level liver infarction (n = 1) which was treated by drainage tube placement, and subsegmental level liver infarction (. Conclusion:New TACE technique, RAIB-TACE, was useful to achieve successful response of large HCC nodules.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Irie T,Takahashi N,Kamoshida T,Kashimura J,Ariga Hdoi
10.1155/2020/9289321subject
Has Abstractpub_date
2020-01-19 00:00:00pages
9289321eissn
2314-6133issn
2314-6141journal_volume
2020pub_type
杂志文章abstract:OBJECTIVES:To study effects of a one-year multicomponent intervention on perceived environmental barriers in hip fracture patients. DESIGN:Randomized controlled trial of a 12-month home-based rehabilitation aiming to improve mobility and function (ISRCTN53680197); secondary analyses. Subjects. Community-dwelling hip f...
journal_title:BioMed research international
pub_type: 杂志文章,随机对照试验
doi:10.1155/2013/769645
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journal_title:BioMed research international
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,随机对照试验
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更新日期:2015-01-01 00:00:00
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
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pub_type: 杂志文章,评审
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pub_type: 临床试验,杂志文章
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更新日期:2015-01-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2017-01-01 00:00:00
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更新日期:2019-04-02 00:00:00
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pub_type: 杂志文章
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更新日期:2013-01-01 00:00:00