Dexmedetomidine Attenuates Lipopolysaccharide Induced MCP-1 Expression in Primary Astrocyte.

abstract：:ELABELA (ELA) is considered to be implicated in the pathophysiology of preeclampsia (PE), since ELA-deficient mice exhibited PE-like symptoms and infusion of exogenous ELA normalized the gestational hypertension (GH) and proteinuria. However, no evidence show that circulating ELA is deficient in early placental develo...

journal_title：BioMed research international

authors： Ma S,Guo C,Zhang J,Long S,Tan H,You Y

更新日期：2020-09-28 00:00:00

abstract：:Stability and mobility in functional motor activities depend on a precise regulation of phasic and tonic muscular activity that is carried out automatically, without conscious awareness. The sensorimotor control of posture involves a complex integration of multisensory inputs that results in a final motor adjustment p...

journal_title：BioMed research international

authors： Rinalduzzi S,Trompetto C,Marinelli L,Alibardi A,Missori P,Fattapposta F,Pierelli F,Currà A

更新日期：2015-01-01 00:00:00

abstract：:Proper placental development and function are central to the health of both the mother and the fetus during pregnancy. A critical component of healthy placental function is the proper development of its vascular network. Poor vascularization of the placenta can lead to fetal growth restriction, preeclampsia, and in so...

journal_title：BioMed research international

authors： Pereira RD,De Long NE,Wang RC,Yazdi FT,Holloway AC,Raha S

更新日期：2015-01-01 00:00:00

abstract：:Background. Central systolic blood pressure (CSBP) has prognostic significance and simplified devices for its estimation have been introduced recently. The aim of this study was to assess the achievement of the target CSBP in treated hypertensive patients. Subjects and Methods. One hundred patients with well-controlle...

journal_title：BioMed research international

authors： Bulas J,Potočárová M,Murín J,Kozlíková K,Luha J,Čaprnda M

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND AND AIM:Chemokine/receptor axis is a predominant actor of clinical disorders. They are key factors of pathogenesis of almost all clinical situations including asthma. Correspondingly, CXCL12 is involved in the immune responses. Therefore, this study was designed to explore the association between gene polymo...

journal_title：BioMed research international

authors： Rafatpanah H,Amin M,Ghasemshirazi M,Kazemiarababadi M,Khorramdelazad H,Abousaidi H,Shabani Z,Sayadi A,Hassanshahi G,Samadi J

更新日期：2013-01-01 00:00:00

abstract：:Bone grafts are medical devices that are in high demand in clinical practice for substitution of bone defects and recovery of atrophic bone regions. Based on the analysis of the modern groups of bone grafts, the particularities of their composition, the mechanisms of their biological effects, and their therapeutic ind...

journal_title：BioMed research international

authors： Deev RV,Drobyshev AY,Bozo IY,Isaev AA

更新日期：2015-01-01 00:00:00

abstract：:Tryptophan (Trp) plays an essential role in pig behavior and growth performances. However, little is known about Trp's effects on tight junction barrier and intestinal health in weaned pigs. In the present study, twenty-four (24) weaned pigs were randomly assigned to one of the three treatments with 8 piglets/treatmen...

journal_title：BioMed research international

authors： Tossou MC,Liu H,Bai M,Chen S,Cai Y,Duraipandiyan V,Liu H,Adebowale TO,Al-Dhabi NA,Long L,Tarique H,Oso AO,Liu G,Yin Y

更新日期：2016-01-01 00:00:00

abstract：:Increased sugar consumption, especially fructose, is strongly related to the development of type 2 diabetes (T2D) and metabolic syndrome. The aim of this study was to evaluate long term effects of fructose supplementation on Wistar rats. Three-week-old male rats were randomly divided into 2 groups: control (C; n = 14)...

journal_title：BioMed research international

authors： Dupas J,Feray A,Goanvec C,Guernec A,Samson N,Bougaran P,Guerrero F,Mansourati J

更新日期：2017-01-01 00:00:00

abstract：:In our study, we evaluated the feasibility of a new sampling method for splenic stiffness (SS) measurement by Quantitative Acoustic Radiation Force Impulse Elastography (Virtual Touch Tissue Quantification (VTTQ)).We measured SS in 54 patients with HCV-related cirrhosis of whom 28 with esophageal varices (EV), 27 with...

journal_title：BioMed research international

authors： Rizzo L,Attanasio M,Pinzone MR,Berretta M,Malaguarnera M,Morra A,L'Abbate L,Balestreri L,Nunnari G,Cacopardo B

更新日期：2014-01-01 00:00:00

abstract：:Hepatitis B virus (HBV) is an important public health problem that poses a serious threat to human health. HBV reactivation generally occurs in overt or occult HBV infection patients who suffered DDAs, chemotherapy, or immunosuppressive therapy, especially when some solid tumors and leukemia patients are using hormone...

journal_title：BioMed research international

authors： Guo L,Wang D,Ouyang X,Tang N,Chen X,Zhang Y,Zhu H,Li X

更新日期：2018-12-26 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the second leading cause of cancer deaths in Taiwan. CD44, one of the well-known tumor markers, plays an essential role in tumor cell differentiation, invasion, and metastasis. We investigated the CD44 single-nucleotide polymorphisms (SNPs) with environmental risk factors related to H...

journal_title：BioMed research international

authors： Chou YE,Hsieh MJ,Chiou HL,Lee HL,Yang SF,Chen TY

更新日期：2014-01-01 00:00:00

abstract：:Vitamin B-6 has a strong antioxidative effect. It would be useful to determine whether vitamin B-6 supplementation had effects on antioxidant capacities in patients with hepatocellular carcinoma (HCC) who had recently undergone tumor resection. Thirty-three HCC patients were randomly assigned to either the placebo (n ...

journal_title：BioMed research international

authors： Cheng SB,Lin PT,Liu HT,Peng YS,Huang SC,Huang YC

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Inflammation has a key role in migraine pathophysiology. Vitamin D is an effective anti-inflammatory agent. The aim of this study was to investigate the association between migraine and two vitamin D receptor (VDR) polymorphisms (TaqI and FokI) and also the relationship between VDR polymorphisms and headache...

journal_title：BioMed research international

authors： Motaghi M,Haghjooy Javanmard S,Haghdoost F,Tajadini M,Saadatnia M,Rafiee L,Zandifar A

更新日期：2013-01-01 00:00:00

abstract：:Internally symmetric proteins are proteins that have a symmetrical structure in their monomeric single-chain form. Around 10-15% of the protein domains can be regarded as having some sort of internal symmetry. In this regard, we previously published SymD (symmetry detection), an algorithm that determines whether a giv...

journal_title：BioMed research international

authors： Jha A,Flurchick KM,Bikdash M,Kc DB

更新日期：2016-01-01 00:00:00

abstract：:The spectrum of kidney disease-associated monoclonal immunoglobulin and plasma cell malignancies is remarkably broad and encompasses nearly all nephropathologic entities. Multiple myeloma with kidney impairment at presentation is a medical emergency since the recovery of kidney function is associated with survival ben...

journal_title：BioMed research international

authors： Mussap M,Merlini G

更新日期：2014-01-01 00:00:00

abstract：:This study investigates the mechanism underlying the improving effect of zinc on fertility in obese rats using proteomics. The effects of three different doses of ZnSO4 on spermatogenesis and hormone levels were studied. Testicular spermatogenesis was observed by HE staining. Serum estrogen and testosterone levels wer...

journal_title：BioMed research international

authors： Ma J,Han R,Li Y,Cui T,Wang S

更新日期：2020-05-04 00:00:00

abstract：:Acetabular fractures involving predominantly the anterior column associated with a disruption of the quadrilateral surface can be treated with instrumentation implementing the stabilization of the quadrilateral surface. The recently introduced suprapectineal quadrilateral buttress plate is specifically designed to pre...

journal_title：BioMed research international

authors： Egli RJ,Keel MJB,Cullmann JL,Bastian JD

更新日期：2017-01-01 00:00:00

abstract：:This prospective randomized study is to evaluate the locoregional failure and its impact on survival by comparing involved field radiotherapy (IFRT) with elective nodal irradiation (ENI) in combination with concurrent chemotherapy for locally advanced non-small cell lung cancer. It appears that higher dose could be de...

journal_title：BioMed research international

authors： Chen M,Bao Y,Ma HL,Hu X,Wang J,Wang Y,Peng F,Zhou QC,Xie CH

更新日期：2013-01-01 00:00:00

abstract：Background and Aims:Concordance between transient elastography (TE) and ultrasonography (US) in assessing liver fibrosis in patients with chronic hepatitis B (CHB) and concurrent nonalcoholic fatty liver disease (NAFLD) has been rarely studied. This study aimed to evaluate the individual and combined performances of TE...

journal_title：BioMed research international

authors： Zhang GL,Zhao QY,Lin CS,Hu ZX,Zhang T,Gao ZL

更新日期：2019-01-23 00:00:00

abstract：:A growing body of evidence has indicated that high-fat diet-induced nonalcoholic fatty liver disease is usually accompanied by oxidized low-density lipoprotein (ox-LDL) deposited in the liver. The current study aimed to investigate the effect of quercetin on high-fat diet-induced ox-LDL accumulation in the liver and t...

journal_title：BioMed research international

authors： Liu L,Gao C,Yao P,Gong Z

更新日期：2015-01-01 00:00:00

abstract：:Polymethylmethacrylate (PMMA) bone cement is a popular bone void filler for vertebroplasty. However, the use of PMMA has some drawbacks, including the material's excessive stiffness, exothermic polymerization, and short handling time. This study aimed to create an ideal modified bone cement to solve the above-mentione...

journal_title：BioMed research international

authors： Tai CL,Lai PL,Lin WD,Tsai TT,Lee YC,Liu MY,Chen LH

更新日期：2016-01-01 00:00:00

abstract：Background:Although sleeve gastrectomy results in good weight loss and metabolic improvements, it is an irreversible procedure. Therefore, we attempted to assess the possibility of creating a sleeved stomach without resection. Material and Methods. A total of 22 male Sprague-Dawley rats with type 2 diabetes were random...

journal_title：BioMed research international

authors： Zhang W,Widjaja J,Yao L,Shao Y,Zhu X,Li C

更新日期：2020-05-01 00:00:00

abstract：Background:The predictive values of monocytes in the prognosis of patients with acute paraquat (PQ) poisoning are unclear. This retrospective study investigated the predictive values of monocytes in the prognosis of patients with acute PQ poisoning. Methods:Adult patients who suffered from acute PQ poisoning in the em...

journal_title：BioMed research international

authors： Zhao Y,Song YQ,Gao J,Feng SY,Li Y

更新日期：2019-07-15 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2015/714230.]. ...

journal_title：BioMed research international

authors： Voss JO,Loebel C,Bara JJ,Fuessinger MA,Duttenhoefer F,Alini M,Stoddart MJ

更新日期：2016-01-01 00:00:00

abstract：Background:Ischemic heart disease (IHD) is the major cause of death in patients with cardiovascular disease. Cardiac remodeling is a common pathological change following myocardial infarction (MI), and cardiomyocyte apoptosis plays a key role in this change. Transcription factor recombination signal-binding protein-J (...

journal_title：BioMed research international

authors： He Y,Pang S,Huang J,Zhu K,Tong J,Tang Y,Ma G,Chen L

更新日期：2018-07-03 00:00:00

abstract：:Recent research had shown a correlation between aging and decreasing Gamma-aminobutyric acid (GABA), the primary inhibitory neurotransmitter in the brain. However, how GABA level varies with age in the medial portion of the brain has not yet been studied. The purpose of this study was to investigate the GABA level var...

journal_title：BioMed research international

authors： He X,Koo BB,Killiany RJ

更新日期：2016-01-01 00:00:00

abstract：:The 13 million nurses worldwide constitute most of the global healthcare workforce and are uniquely positioned to engage with others to address disparities in healthcare to achieve the goal of better health for all. A new vision for nurses involves active participation and collaboration with international colleagues a...

journal_title：BioMed research international

authors： Premji SS,Hatfield J

更新日期：2016-01-01 00:00:00

abstract：:Triple-negative breast cancer (TNBC) has a significant clinical relevance of being associated with a shorter median time to relapse and death and does not respond to endocrine therapy or other available targeted agents. Increased aggressiveness of this tumor, as well as resistance to standard drug therapies, may be as...

journal_title：BioMed research international

authors： Collina F,Di Bonito M,Li Bergolis V,De Laurentiis M,Vitagliano C,Cerrone M,Nuzzo F,Cantile M,Botti G

更新日期：2015-01-01 00:00:00

abstract：:Taenia solium thioredoxin-1 gene (TsTrx-1) has a length of 771 bp with three exons and two introns. The core promoter gene presents two putative stress transcription factor binding sites, one putative TATA box, and a transcription start site (TSS). TsTrx-1 mRNA is expressed higher in larvae than in adult. This gene en...

journal_title：BioMed research international

authors： Jiménez L,Rodríguez-Lima O,Ochoa-Sánchez A,Landa A

更新日期：2015-01-01 00:00:00

abstract：:Clear cell renal cell carcinoma (ccRCC) is one of the most common cancers in the world. Our aim is to identify prognostic biomarkers that contribute to the progression of early stage ccRCC and clarify the mechanism. Here, the mRNA microarray expression profile of ccRCC samples was obtained from Gene Expression Omnibus...

journal_title：BioMed research international

authors： Qiu X,Gu Y,Ni Y,Li Q

更新日期：2020-10-29 00:00:00