Abstract:
:Bacterial infections are the most common cause of purulent soft tissue inflammations in the head and neck area. These bacteria are also responsible for the majority of inflammatory complications after third molar removal. The key to success of antibacterial treatment in both cases is the use of an appropriate antibacterial agent. The aim of the study was to evaluate the susceptibility profile of bacteria isolated from material collected from patients with intraoral odontogenic abscesses. The test material consisted of swabs taken from the odontogenic abscesses, after their incision and drainage. Another swab was collected from the lesion area, 10 days after the initial visit. Results were compared with an identical study conducted on a control group of healthy patients, who had undergone third molar removal. Bacteria identified in this study consisted of aerobic and anaerobic strains, both Gram-positive and Gram-negative. According to the EUCAST guidelines, none of the tested antibiotics was recommended for all identified bacteria. The percentage of bacterial strains sensitive to amoxicillin and clavulanic acid was 78.13% and 81.48% in the study and control groups, respectively, whereas, the percentage of those sensitive to clindamycin was 96.43% and 80.00%, respectively. For Gram-negative aerobic bacteria, gentamicin and ciprofloxacin were among medications affecting all cultured species. 100.00% of strains were found to be susceptible to these antibiotics. Statistically significant relationship between the presence of Gram-negative aerobic strains and the occurrence of complications was found. In the case of the most frequently occurring bacteria in the study, amoxicillin with clavulanic acid and clindamycin were shown to be very effective. In cases of severe purulent odontogenic inflammations, it is recommended to use a combination of antibiotics. Amoxicillin with ciprofloxacin and clindamycin with cefuroxime seem to be the proper choices based on the results of this study.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Bogacz M,Morawiec T,Śmieszek-Wilczewska J,Janowska-Bogacz K,Bubiłek-Bogacz A,Rój R,Pinocy K,Mertas Adoi
10.1155/2019/2010453subject
Has Abstractpub_date
2019-10-07 00:00:00pages
2010453eissn
2314-6133issn
2314-6141journal_volume
2019pub_type
杂志文章abstract:BACKGROUND:Although expression of miR-200s is aberrant in liver fibrosis, its role in liver fibrogenesis still remains unknown. Here, we investigated the role of miR-200c in the activation of human hepatic stellate cells (HSCs) and induction of liver fibrosis. METHODS:We engineered human HSCs (LX2 cell line) to stably...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/2670658
更新日期:2017-01-01 00:00:00
abstract::The biological age (BA) equation is a prediction model that utilizes an algorithm to combine various biological markers of ageing. Different from traditional concepts, the BA equation does not emphasize the importance of a golden index but focuses on using indices of vital organs to represent the senescence of whole b...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2016/4697017
更新日期:2016-01-01 00:00:00
abstract::The early diagnosis of Alzheimer's disease (AD) and mild cognitive impairment (MCI) is very important for treatment research and patient care purposes. Few biomarkers are currently considered in clinical settings, and their use is still optional. The objective of this work was to determine whether multimodal and nonpr...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/961314
更新日期:2015-01-01 00:00:00
abstract::Preterm birth remains the most prevalent cause of neonatal morbidity. This study aimed to evaluate the diagnostic value of SDF-1α, resistin, secretory RAGE (sRAGE), and endogenous secretory RAGE (esRAGE) in preterm labor. A total of 211 pregnant women participated in the study. Group A contained 72 women between 22 an...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/2719460
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:Firstly, to, through instrumentation with the iPhone4 smartphone, measure and describe variability of tridimensional acceleration, angular velocity, and displacement of the trunk in the turn transition during the ten-meter Extended Timed-Get-up-and-Go test in two groups of frail and physically active elderly ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/279197
更新日期:2013-01-01 00:00:00
abstract::Escherichia coli O157:H7 is the main causative agent of haemolytic uremic syndrome. Cattle are the main reservoir of these bacteria, and have been shown to develop immune response to colonization. Our aim was to investigate the faecal shedding pattern of E. coli O157:H7 in calves challenged intragastrically with eithe...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/290679
更新日期:2015-01-01 00:00:00
abstract:Aim:The aim of this study was to explore the correlation of chemokine receptor CXCR3 with M2 macrophage infiltration, various clinicopathological features, and prognosis in patients diagnosed with gastric cancer (GC). Methods:Expression of CXCR3 protein and M2 macrophage was evaluated in 156 GC patients and correspond...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/6832867
更新日期:2019-05-21 00:00:00
abstract::Cancer and diabetes are among the most common diseases in western societies. Epidemiological studies have shown that diabetic patients have a significantly higher risk of developing a number of different types of cancers and that individuals with comorbidity (cancer and diabetes/prediabetes) have a poorer prognosis re...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/165105
更新日期:2015-01-01 00:00:00
abstract::Saponins are a group of naturally occurring plant glycosides with the features of their strong foam-forming properties and multibiological effects such as antitumor activity. Though Misaponin B, one of the triterpenoid saponins from Madhuca longifolia, is known to have spermicidal and antioxidant activity, the other b...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/5925094
更新日期:2020-02-07 00:00:00
abstract::We have determined patient's amyloid subtype through immunohistochemical and proteomic analyses of formalin-fixed, paraffin-embedded (FFPE) tissue samples from two affected organs per patient. Amyloid typing, via immunohistochemistry (IHC) and laser microdissection followed by the combination of liquid chromatography ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/3689091
更新日期:2019-01-31 00:00:00
abstract:Aim:To investigate the effect of fecal microbiota transplantation on visceral hypersensitivity compared with Bifidobacterium longum. Methods:Mice visceral hypersensitivity was induced by Trichinella spiralis. After 8 weeks, they were divided into three groups (controls, Bifidobacterium longum, and fecal microbiota tra...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/3860743
更新日期:2018-01-30 00:00:00
abstract::Two field isolates of Rhizoctonia solani were isolated from infected paddy plants in Malaysia. These isolates were verified via ITS-rDNA analysis that yielded ~720 bp products of the ITS1-5.8S-ITS4 region, respectively. The sequenced products showed insertion and substitution incidences which may result in strain dive...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/434257
更新日期:2014-01-01 00:00:00
abstract::Actin is one of the most highly conserved proteins and plays crucial roles in many vital cellular functions. In most eukaryotes, it is encoded by a multigene family. Although the actin gene family has been studied a lot, few investigators focus on the comparison of actin gene family in relative species. Here, the purp...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/630803
更新日期:2013-01-01 00:00:00
abstract::Remote organ impairments are frequent and increase patient morbidity and mortality after lower limb ischemia-reperfusion (IR). We challenged the hypothesis that lower limb IR might also impair lung, renal, and liver mitochondrial respiration. Two-hour tourniquet-induced ischemia was performed on both hindlimbs, follow...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/392390
更新日期:2014-01-01 00:00:00
abstract::[This corrects the article DOI: 10.1155/2017/6353510.]. ...
journal_title:BioMed research international
pub_type: 杂志文章,已发布勘误
doi:10.1155/2018/5189346
更新日期:2018-09-26 00:00:00
abstract::In the present study, we explored SA's activity against DOX-induced cardiotoxicity and revealed its underlying mechanisms. Male Wistar rats (weight, 190-210g; n = 6) were randomly divided into four groups: group I, normal control; group II, DOX 15 mg/kg via intraperitoneal (ip) route; group III, administered DOX+SA 20...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/3921796
更新日期:2020-03-10 00:00:00
abstract:OBJECTIVE:To investigate the joint effects of the single nucleotide polymorphisms (SNPs) of genes in the folic acid pathway on homocysteine (Hcy) metabolism. METHODS:Four hundred women with normal pregnancies were enrolled in this study. SNPs were identified by MassARRAY. Serum folic acid and Hcy concentration were me...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/560183
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:To investigate the effect of two foot placements (normal or posterior placement) and three arm positions (hands on the thighs, arms crossed over chest, and augmented arm position with elbow extended) on the five times sit-to-stand (FTSTS) test times of individuals with chronic stroke. DESIGN:Cross-sectional...
journal_title:BioMed research international
pub_type: 杂志文章,随机对照试验
doi:10.1155/2014/636530
更新日期:2014-01-01 00:00:00
abstract::The similarity-based retrieval of lung nodule computed tomography (CT) images is an important task in the computer-aided diagnosis of lung lesions. It can provide similar clinical cases for physicians and help them make reliable clinical diagnostic decisions. However, when handling large-scale lung images with a gener...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/3162649
更新日期:2016-01-01 00:00:00
abstract::Melanoma is a human skin malignant tumor with high invasion and poor prognosis. The limited understanding of genomic alterations in melanomas in China impedes the diagnosis and therapeutic strategy selection. We conducted comprehensive genomic profiling of melanomas from 39 primary and metastatic formalin-fixed paraff...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/6096814
更新日期:2020-01-30 00:00:00
abstract::Postoperative cognitive dysfunction (POCD) is a kind of serious neurologic complications and dexmedetomidine has a certain effect on POCD. However, functional mechanism of dexmedetomidine on POCD still remains unclear, so the research mainly studied the effect of dexmedetomidine on cognitive function and protein expre...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/4014021
更新日期:2018-01-16 00:00:00
abstract::High mobility group box 1 (HMGB1) is an ubiquitous protein that plays different roles in the nucleus, cytoplasm, and extracellular space. It is an important DAMP molecule that allows communication between damaged or tumor cells and the immune system. Tumor cells exploit HMGB1's ability to activate intracellular pathwa...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/512027
更新日期:2015-01-01 00:00:00
abstract::Targeted drug delivery using folate receptors is one of the most interesting chemotherapeutic research areas over the past few years. A novel folate targeted copolymer was synthesized using dextran stearate coupled to folic acid. FT-IR and NMR spectroscopy were used to confirm successful conjugation. Micelles prepared...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/708593
更新日期:2014-01-01 00:00:00
abstract:Background:Urogenital schistosomiasis remains a public health problem in Tanzania. Control programs mostly target school-going children ignoring other vulnerable groups like women of child bearing age. Previous evidence has shown that women of reproductive age suffer greatest morbidities in endemic areas. This study so...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/5923025
更新日期:2020-10-23 00:00:00
abstract::Cognitive dysfunction is an important complicated disease in obesity. Exercise ameliorates obesity and the related cognitive dysfunction. However, the underlying mechanism is still unclear. In this study, we investigated whether aerobic interval training (AIT) could attenuate high-fat-diet- (HFD-) associated cognitive...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/2708491
更新日期:2018-03-22 00:00:00
abstract::The microbial safety and stability of minimally processed foods are based on the application of combined preservative factors. Since microorganisms are able to develop adaptive networks to survive under conditions of stress, food safety may be affected, and therefore understanding of stress adaptive mechanisms plays a...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/548930
更新日期:2015-01-01 00:00:00
abstract::Effects of in ovo injection of Q10 on hatchability, performance (feed intake (FI), body weight gain (BWG), feed/gain ratio (F/G)) traits, and immune status of Ross × Ross 308 broiler chicks, hatched from eggs laid by a 38-week-old breeder flock, were determined through 42 days after hatch. Eggs containing live embryos...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/7167525
更新日期:2019-02-04 00:00:00
abstract::The objective of the current research was to review and update evidence on the dietary effect of the consumption of tagatose in type 2 diabetes, as well as to elucidate the current approach that exists on its production and biotechnological utility in functional food for diabetics. Articles published before July 1, 20...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2018/8718053
更新日期:2018-01-09 00:00:00
abstract::Hepatitis B virus (HBV) infection is the predominant risk factor for chronic hepatitis B (CHB). The association between HBV infection and human leukocyte antigen- (HLA-) DQ polymorphism (rs2856718 and rs7453920) has been demonstrated in other studies; however, the results were controversial or inconclusive. Therefore,...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析
doi:10.1155/2017/9679843
更新日期:2017-01-01 00:00:00
abstract::Lung illness encountered in patients with rheumatic diseases bears clinical significance in terms of increased morbidity and mortality as well as potential challenges placed on patient care. Although our understanding of natural history of this important illness is still limited, epidemiologic knowledge has been accum...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2018/6930297
更新日期:2018-05-08 00:00:00