Characterizations of Gene Alterations in Melanoma Patients from Chinese Population.

abstract：BACKGROUND AND PURPOSE:The vasoconstrictor endothelin-1 (ET-1) has been implicated in the pathogenesis of cerebral vasospasm following subarachnoid hemorrhage (SAH). Previous results showed that CGS 26303, an endothelin converting enzyme (ECE) inhibitor, effectively prevented and reversed arterial narrowing in animal m...

journal_title：BioMed research international

authors： Wang CJ,Lee PY,Wu BN,Wu SC,Loh JK,Tsai HP,Chung CL,Kassell NF,Kwan AL

更新日期：2014-01-01 00:00:00

abstract：:Neutrophils comprise the first line of innate immune defense during a host-pathogen interaction. They attack microorganisms directly through three different methods, of which, phagocytosis and degranulation have been known and well-studied for decades. The formation of neutrophil extracellular traps (NETs) is the thir...

journal_title：BioMed research international

authors： Alasmari SZ

更新日期：2020-02-01 00:00:00

abstract：:Liver transplantation is the best treatment option for early-stage hepatocellular carcinoma, liver cirrhosis, fulminant liver failure, and end-stage liver diseases. Even though advances in surgical techniques and perioperative care have improved postoperative outcomes, perioperative cardiovascular complications are a ...

journal_title：BioMed research international

authors： Choi JM,Kong YG,Kang JW,Kim YK

更新日期：2017-01-01 00:00:00

abstract：:Dietary polyphenols present in a broad range of plant foods have been related to beneficial health effects. This review aims to update the current information about the modulation of the gut microbiota by dietary phenolic compounds, from a perspective based on the experimental approaches used. After referring to gener...

journal_title：BioMed research international

authors： Dueñas M,Muñoz-González I,Cueva C,Jiménez-Girón A,Sánchez-Patán F,Santos-Buelga C,Moreno-Arribas MV,Bartolomé B

更新日期：2015-01-01 00:00:00

abstract：:Accumulating evidence reveals that the sirtuin family is involved in the pathology of Parkinson's disease (PD). However, the association between the polymorphisms of the sirtuin gene and the risk of PD remains elusive. Here, we investigated the possible association of nine SIRT1 and SIRT2 SNPs with the risk of PD thro...

journal_title：BioMed research international

authors： Chen X,Mai H,Chen X,Cai Y,Cheng Q,Chen X,Li X,Fan W,Tang P,Ou M,Yang J,Chen Y,Cui L

更新日期：2019-05-12 00:00:00

abstract：:Libidibia ferrea (LF) is a medicinal plant that holds many pharmacological properties. We evaluated the antinociceptive effect in the LF aqueous seed extract and Lipidic Portion of Libidibia ferrea (LPLF), partially elucidating their mechanisms. Histochemical tests and Gas chromatography of the LPLF were performed to ...

journal_title：BioMed research international

authors： Sawada LA,Monteiro VS,Rabelo GR,Dias GB,Da Cunha M,do Nascimento JL,Bastos Gde N

更新日期：2014-01-01 00:00:00

abstract：Purpose:In this study, we examined whether the associations between working hours, job satisfaction, and work-life balance are mediated by occupational stress. In addition, we tested whether perceived time control helps moderate the effects of working hours and occupational stress. Methodology:Questionnaires were admi...

journal_title：BioMed research international

authors： Hsu YY,Bai CH,Yang CM,Huang YC,Lin TT,Lin CH

更新日期：2019-06-23 00:00:00

abstract：Background:Anion gap (AG) has been proved to be associated with prognosis of many cardiovascular diseases. This study is aimed at exploring the association of AG with inhospital all-cause mortality and adverse clinical outcomes in coronary care unit (CCU) patients. Method:All data of this study was extracted from Medi...

journal_title：BioMed research international

authors： Sun T,Cai C,Shen H,Yang J,Guo Q,Zhang J,Zhang B,Ding Y,Zhou Y

更新日期：2020-08-27 00:00:00

abstract：:Glioblastoma (GBM) is the most common and malignant intracranial tumor in adults. Despite continuous improvements in diagnosis and therapeutic method, the prognosis is still far away from expectations. The invasive phenotype of GBM is the main reason for the poor prognosis. Epithelial-mesenchymal transition (EMT) is r...

journal_title：BioMed research international

authors： Song Y,Chen Y,Li Y,Lyu X,Cui J,Cheng Y,Zheng T,Zhao L,Zhao G

更新日期：2019-04-17 00:00:00

abstract：:The present study deals with the enzymatic synthesis of biodiesel by transesterification of Jatropha oil (Jatropha curcas L.) with ethanol in a solvent-free system. Seven commercial lipase preparations immobilized by covalent attachment on epoxy-polysiloxane-polyvinyl alcohol composite (epoxy-SiO2-PVA) were tested as ...

journal_title：BioMed research international

authors： Souza LT,Mendes AA,de Castro HF

更新日期：2016-01-01 00:00:00

abstract：:COVID-19 is a pandemic which has spread to more than 200 countries. Its high transmission rate makes it difficult to control. To date, no specific treatment has been found as a cure for the disease. Therefore, prediction of COVID-19 cases provides a useful insight to mitigate the disease. This study aims to model and ...

journal_title：BioMed research international

authors： Attanayake AMCH,Perera SSN

更新日期：2020-12-03 00:00:00

abstract：:Mitochondrial uncoupling protein 2 (UCP2) is suggested to have a role in the development of nonalcoholic steatohepatitis (NASH). However, the mechanism remains unclear. Autophagy is an important mediator of many pathological responses. This study aims to investigate the relationship between UCP2 and hepatoma cells aut...

journal_title：BioMed research international

authors： Lou J,Wang Y,Wang X,Jiang Y

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:We aimed to identify certain genes related to response to infliximab (IFX) and biomarkers to predict the IFX effect for Japanese Crohn's disease (CD) patients by performing an association study of single nucleotide polymorphisms (SNPs) in candidate genes in the interleukin- (IL-) 17 signaling pathway with re...

journal_title：BioMed research international

authors： Urabe S,Isomoto H,Ishida T,Maeda K,Inamine T,Kondo S,Higuchi N,Sato K,Uehara R,Yajima H,Machida H,Chen CC,Fukuda Y,Takeshima F,Nakao K,Tsukamoto K

更新日期：2015-01-01 00:00:00

abstract：Background:Glucagon-like peptide 1 (GLP-1) hormone is an incretin hormone that is secreted in the ileum and plays a role in the pancreas to increase insulin secretion, stimulate proliferation, and prevent pancreatic β-cell apoptosis. Currently, diabetes mellitus (DM) treatment based on GLP-1 work is being developed, fo...

journal_title：BioMed research international

authors： Kartinah NT,Fadilah F,Ibrahim EI,Suryati Y

更新日期：2019-11-11 00:00:00

abstract：:The aim of this study was to develop a freeze-drying protocol facilitating successful processing of plant material containing the small surface antigen of hepatitis B virus (S-HBsAg) while preserving its VLP structure and immunogenicity. Freeze-drying of the antigen in lettuce leaf tissue, without any isolation or pur...

journal_title：BioMed research international

authors： Czyż M,Dembczyński R,Marecik R,Wojas-Turek J,Milczarek M,Pajtasz-Piasecka E,Wietrzyk J,Pniewski T

更新日期：2014-01-01 00:00:00

abstract：:A comparison of the superior and inferior rectus muscles was performed to determine whether they have similar structures and innervation attributable to their participation in the same type of, although antagonistic, eye movements. The study was conducted on 70 cadaveric hemiheads, and the anatomical variations in the...

journal_title：BioMed research international

authors： Haładaj R,Polguj M,Tubbs RS

更新日期：2020-04-30 00:00:00

abstract：:Hepatitis B virus (HBV) is an important public health problem that poses a serious threat to human health. HBV reactivation generally occurs in overt or occult HBV infection patients who suffered DDAs, chemotherapy, or immunosuppressive therapy, especially when some solid tumors and leukemia patients are using hormone...

journal_title：BioMed research international

authors： Guo L,Wang D,Ouyang X,Tang N,Chen X,Zhang Y,Zhu H,Li X

更新日期：2018-12-26 00:00:00

abstract：:Gedunin is one of the major compounds found in the neem tree (Azadirachta indica). In the present study, antiproliferative potential of gedunin was evaluated in human embryonal carcinoma cells (NTERA-2, a cancer stem cell model) and peripheral blood mononuclear cells (PBMCs), using Sulforhodamine (SRB) and WST-1 assay...

journal_title：BioMed research international

authors： Tharmarajah L,Samarakoon SR,Ediriweera MK,Piyathilaka P,Tennekoon KH,Senathilake KS,Rajagopalan U,Galhena PB,Thabrew I

更新日期：2017-01-01 00:00:00

abstract：:The effect of crocetin (C20H24O4) on methylcholanthrene- (MCA-) induced uterine cervical cancer in mice was studied in this paper. After the mice were treated orally with crocetin, maleic dialdehyde (MDA), polymorphonuclear cells (PMN), interleukin-1β (IL-1β), and tumor necrosis factor-α (TNF-α) were examined by ELISA...

journal_title：BioMed research international

authors： Chen B,Hou ZH,Dong Z,Li CD

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:End-stage renal disease (ESRD) is an important cause of morbidity and mortality in patients with systemic lupus erythematosus (SLE). OBJECTIVES:To analyze the outcome and prognostic factors of renal transplantation in patients with ESRD due to SLE from January 1986 to December 2013 in a single center. RESU...

journal_title：BioMed research international

authors： Cairoli E,Sanchez-Marcos C,Espinosa G,Glucksmann C,Ercilla G,Oppenheimer F,Cervera R

更新日期：2014-01-01 00:00:00

abstract：:A Mycobacterium bovis knockout in p27-p55 operon was tested as an antituberculosis experimental vaccine in animal models. The mutant MbΔp27-p55 was significantly more attenuated in nude mice than its parental strain but more virulent than BCG Pasteur. Challenge experiments in mice and guinea pigs using M. bovis or M. ...

journal_title：BioMed research international

authors： Bianco MV,Clark S,Blanco FC,Garbaccio S,García E,Cataldi AA,Williams A,Bigi F

更新日期：2014-01-01 00:00:00

abstract：:Any bioassay to test new chemically synthesized larvicides or phytolarvicides against Culicidae and more harmful mosquito species, such as Aedes aegypti and Aedes albopictus, which specifically transmit dengue, yellow fever, chikungunya viral fevers as well as Zika virus, or Anopheles gambiae, a vector for malaria and...

journal_title：BioMed research international

authors： Fontana JD,Ferreira RL,Zuccolotto T,de Borba Dallagassa C,Wielewski LP,Chalcoski BMS,da Silva MAN,Richardi VS,Golart J,de Melo Rodovalho C

更新日期：2020-08-29 00:00:00

abstract：:Background and Objective. Although minimally invasive surgical treatment of acute epidural hematoma attracts increasing attention, no generalized indications for the surgery have been adopted. This study aimed to evaluate the effects of minimally invasive surgery in acute epidural hematoma with various hematoma volume...

journal_title：BioMed research international

authors： Wang W

更新日期：2016-01-01 00:00:00

abstract：:Angiopoietin-like protein 4 (ANGPTL4) is widely known as a key regulator of lipid metabolism. We investigated the relationship between ANGPTL4 expression in serum or urine and blood lipid or urine protein levels of patients with hyperlipidemia- (HL-) related proteinuria. Sixty-eight patients with HL-related proteinuri...

journal_title：BioMed research international

authors： Gao X,Zhang M,Feng W,Xu Z,Wang Y,Shi L,Zhang J

更新日期：2020-03-23 00:00:00

abstract：Objective:To compare the effectiveness of arthroscopic partial meniscectomy (APM) and physical therapy (PT) for degenerative meniscus tears. Method:We conducted a literature search through PubMed, Embase, the Cochrane Central Register of Controlled Trials, and ClinicalTrials.gov. Randomized controlled trials in adults...

journal_title：BioMed research international

authors： Li J,Zhu W,Gao X,Li X

更新日期：2020-03-03 00:00:00

abstract：OBJECTIVE:To analyze the clinical relevance of the levels of TNFα blockers and anti-drug antibodies (anti-drug Ab) in patients with rheumatoid arthritis (RA) and spondyloarthritis (SpA) treated with adalimumab (ADA), etanercept (ETA), or infliximab (INF) for a prolonged period of time. METHODS:Clinical characteristics...

journal_title：BioMed research international

authors： Arstikyte I,Kapleryte G,Butrimiene I,Venalis A

更新日期：2015-01-01 00:00:00

abstract：:In eukaryotic cells, proteasomes perform crucial roles in many cellular pathways by degrading proteins to enforce quality control and regulate many cellular processes such as cell cycle progression, signal transduction, cell death, immune responses, metabolism, protein-quality control, and development. The catalytic h...

journal_title：BioMed research international

authors： Muñoz C,San Francisco J,Gutiérrez B,González J

更新日期：2015-01-01 00:00:00

abstract：:Alterations in muscle protein turnover of the unaffected side of stroke patients could contribute to physical disability. We investigated whether hypercatabolic activity occurred in unaffected arm muscle and whether supplemented essential amino acids (EAAs) could limit muscle hypercatabolism (MH). Thirty-eight dysphag...

journal_title：BioMed research international

authors： Aquilani R,Boselli M,D'Antona G,Baiardi P,Boschi F,Viglio S,Iadarola P,Pasini E,Barbieri A,Dossena M,Bongiorno AI,Verri M

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:Lipoprotein-associated phospholipase A2 (Lp-PLA2), a marker of vascular inflammation, is associated with cardiovascular disease. This prospective study of an inception cohort aimed to investigate whether the level of Lp-PLA2 is associated with subclinical atherosclerosis in patients with rheumatoid arthritis ...

journal_title：BioMed research international

authors： Södergren A,Karp K,Bengtsson C,Möller B,Rantapää-Dahlqvist S,Wållberg-Jonsson S

更新日期：2015-01-01 00:00:00

abstract：:MicroRNAs (miRs) are small noncoding RNA molecules and recently have demonstrated that altered expression and functions are their tight association with ulcerative colitis (UC). Previous microarray study reported that miR-214 was downregulated in the sigmoid colon of patients with active UC, but the roles of miR-214 i...

journal_title：BioMed research international

authors： Li JA,Wang YD,Wang K,Wang ZL,Jia DY,Yang BY,Xiong CB

更新日期：2017-01-01 00:00:00