Biomaterials-based modulation of the immune system.

abstract：:Triglyceride-glucose index (TyG index) is associated with type 2 diabetes mellitus (T2DM), but research on this relationship is limited in Japan. The purpose of this study was to evaluate the correlation between TyG index and the risk of T2DM in the Japanese population. Here, 12732 participants were selected from the ...

journal_title：BioMed research international

authors： Liu EQ,Weng YP,Zhou AM,Zeng CL

更新日期：2020-12-11 00:00:00

abstract：:Fibrosarcomas are rare malignant mesenchymal tumors originating from fibroblasts. Importantly, fibrosarcoma cells were shown to have a high content and turnover of extracellular matrix (ECM) components including hyaluronan (HA), proteoglycans, collagens, fibronectin, and laminin. ECMs are complicated structures that s...

journal_title：BioMed research international

authors： Nikitovic D,Kouvidi K,Karamanos NK,Tzanakakis GN

更新日期：2013-01-01 00:00:00

abstract：:The crude ethanolic extract from aerial parts of Pothomorphe umbellata L. (Piperaceae) and fractions obtained by partitions sequentially among water-methanol, methylene chloride, and ethyl acetate, as well as the major constituent, 4-nerolidylcatechol, were, respectively, evaluated and evidenced for antioxidant and cy...

journal_title：BioMed research international

authors： Lopes AP,Bagatela BS,Rosa PC,Nanayakkara DN,Tavares Carvalho JC,Maistro EL,Bastos JK,Perazzo FF

更新日期：2013-01-01 00:00:00

abstract：:Due to alarming increase in population and rapid industrialization, drinking water quality is being deteriorated day by day in Pakistan. This review sums up the outcomes of various research studies conducted for drinking water quality status of different areas of Pakistan by taking into account the physicochemical pro...

journal_title：BioMed research international

authors： Daud MK,Nafees M,Ali S,Rizwan M,Bajwa RA,Shakoor MB,Arshad MU,Chatha SAS,Deeba F,Murad W,Malook I,Zhu SJ

更新日期：2017-01-01 00:00:00

abstract：:Host jump can result in deadly pandemic events when avian influenza A viruses broaden their host specificity and become able to infect mammals, including humans. Haemagglutinin-the major capsid protein in influenza A viruses-is subjected to high rate mutations, of which several occur at its "head": the receptor-bindin...

journal_title：BioMed research international

authors： Righetto I,Filippini F

更新日期：2018-05-17 00:00:00

abstract：:Models using large animals that are suitable for studying artificial liver support system (ALSS) are urgently needed. Presently available acute liver failure (ALF) models mainly involve pigs or dogs. Establishment of current surgical ALF models (hepatectomy/devascularization) requires either very good surgical skills ...

journal_title：BioMed research international

authors： Cai L,Weng J,Feng L,He G,Qin J,Zhang Z,Li Y,Peng Q,Jiang Z,Pan M,Gao Y

更新日期：2016-01-01 00:00:00

abstract：:Although disorders of the stomatognathic system are common, the mechanisms involved are unknown. Our objective was to study the changes in the masseter muscles after unilateral exodontia. Molar extraction was performed on Wistar rats (left side), and the animals were sacrificed after either 14 or 26 days. The masseter...

journal_title：BioMed research international

authors： Guerra Cde S,Carla Lara Pereira Y,Issa JP,Luiz KG,Guimarães EA,Gerlach RF,Iyomasa MM

更新日期：2014-01-01 00:00:00

abstract：:We have analyzed anatomic variations in the pectoralis major and pectoralis minor muscles of common chimpanzees (Pan troglodytes) and bonobos (Pan paniscus) and compared them to anatomic variations in these muscles in humans (Homo sapiens). We have macroscopically dissected these muscles in six adult Pan troglodytes, ...

journal_title：BioMed research international

authors： Potau JM,Arias-Martorell J,Bello-Hellegouarch G,Casado A,Pastor JF,de Paz F,Diogo R

更新日期：2018-01-21 00:00:00

abstract：:The aim was to evaluate three different biodegradable polylactic acid- (PLA-) based osteosynthesis materials (OM). These OM (BioSorb, LactoSorb, and Delta) were used in 64 patients of whom 55 (85.9%) had fractures of the zygoma, five (7.8%) in the LeFort II level, two of the frontal bone (3.1%), and two of the maxilla...

journal_title：BioMed research international

authors： Kolk A,Köhnke R,Saely CH,Ploder O

更新日期：2015-01-01 00:00:00

abstract：:Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disease characterized by variable expressivity, age penetrance, and a high heterogeneity. The transcriptional profile (miRNAs, mRNAs), epigenetic modifications, and posttranslational modifications seem to be highly relevant for the onset of the disease. miRNAs...

journal_title：BioMed research international

authors： Roma-Rodrigues C,Raposo LR,Fernandes AR

更新日期：2015-01-01 00:00:00

abstract：:A point mutation of mitochondrial DNA (mtDNA) at nucleotide position 3243 A to G (mt.3243A>G) is involved in many common diseases, including maternally inherited diabetes and deafness (MIDD) and mitochondrial encephalomyopathy, lactic acidosis with stroke-like episodes (MELAS). However, the mutant level of mt.3243A>G ...

journal_title：BioMed research international

authors： Rong E,Wang H,Hao S,Fu Y,Ma Y,Wang T

更新日期：2018-11-13 00:00:00

abstract：:Purpose. The long-term outcomes of patients after discharge from tertiary ICUs as they relate to the public versus private healthcare systems in Brazil have not yet been evaluated. Materials and Methods. A multicenter prospective cohort study was conducted to compare the all-cause mortality and the physical functional...

journal_title：BioMed research international

authors： Dexheimer Neto FL,Rosa RG,Duso BA,Haas JS,Savi A,Cabral Cda R,Maccari JG,de Oliveira RP,Antônio AC,Castro Pde S,Teixeira C

更新日期：2016-01-01 00:00:00

abstract：Background:Inflammation is the major risk factor for the progression of hepatocellular carcinoma (HCC), and the nuclear factor-κB (NF-κB) signaling plays the central role in the inflammation process. However, the activated mechanism of NF-κB signaling in HCC is unclear. Methods:The expression of PHF5A is examined by q...

journal_title：BioMed research international

authors： Yang Q,Zhang J,Xu S,Jia C,Meng W,Tang H,Zhang X,Zhang Y,Fu B

更新日期：2019-01-15 00:00:00

abstract：:Increasing studies have revealed that long noncoding RNAs (lncRNAs) are not transcriptional noise but play important roles in the regulation of a wide range of biological processes, and the dysregulation of lncRNA genes is associated with disease development. Alzheimer's disease (AD) is a chronic neurodegenerative dis...

journal_title：BioMed research international

authors： Wan G,Zhou W,Hu Y,Ma R,Jin S,Liu G,Jiang Q

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:This study aimed to compare the effects of rectal midazolam addition after applying bupivacaine and caudal anesthesia on postoperative analgesia time, the need for additional analgesics, postoperative recovery, and sedation and to find out its adverse effects in children having lower abdominal surgery. METH...

journal_title：BioMed research international

authors： Saylan S,Eroglu A,Dohman D

更新日期：2014-01-01 00:00:00

abstract：:Gastric cancer (GC) is one of the most common and fatal malignancies worldwide. MicroRNAs (miRNAs) play a critical role in tumor initiation, proliferation, and metastasis of gastric cancer. miR193b has been identified as a tumor suppressor in a variety of tumor types; however, its role in gastric cancer is yet to be d...

journal_title：BioMed research international

authors： Tian R,Jiang H,Shao L,Yu Y,Guo Q,Cao B,Guo S

更新日期：2020-05-25 00:00:00

abstract：:Pinelliae Rhizoma Praeparatum Cum Alumine (PRPCA) is useful for eliminating dampness and phlegm in clinical settings, targeting the main mechanisms of insomnia as defined in traditional Chinese medicine. However, little is known regarding the sedative and hypnotic effects of PRPCA. In the present study, we examined th...

journal_title：BioMed research international

authors： Lin S,Nie B,Song K,Ye R,Yuan Z

更新日期：2019-04-28 00:00:00

abstract：:Polymyxin E or colistin, produced by Paenibacillus polymyxa, is an important antibiotic against Gram-negative pathogens. The objective of this study is to evaluate the effect of starch in fermentation medium on colistin biosynthesis in P. polymyxa. The results indicated that replacement of glucose by starch stimulated...

journal_title：BioMed research international

authors： Yu Z,Sun Z,Yin J,Qiu J

更新日期：2018-10-14 00:00:00

abstract：Objectives:Obstructive sleep apnea (OSA) is a common disorder influenced by genetic and environmental factors. Mutations of AT-hook DNA-binding motif containing 1 (AHDC1) gene have been implicated which could cause rare syndromes presenting OSA. This study aims to investigate some rare mutations of AHDC1 in Chinese Han...

journal_title：BioMed research international

authors： Yang S,Li K,Zhu MM,Yuan XD,Jiao XL,Yang YY,Li J,Li L,Zhang HN,Du YH,Wei YX,Qin YW

更新日期：2019-10-13 00:00:00

abstract：Objective:To analyze the ten-year surgical outcomes and postoperative complications of French-Door laminoplasty (FDL) in the management of multilevel cervical spondylotic myelopathy (MCSM) and analyze the prognostic factors for FDL in treating MCSM. Methods:64 patients with MCSM, who were operated by FDL, were include...

journal_title：BioMed research international

authors： Chen G,Liu X,Chen N,Chen B,Zou X,Wei F,Liu S

更新日期：2020-05-06 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of docetaxel plus oxaliplatin and capecitabine (DOX) in the first line treatment of advanced gastric adenocarcinoma. METHODS:A total of 37 patients were enrolled into this study, and they received DOX regimen (docetaxel 75 mg/m² and oxaliplatin 130 mg/m² intravenous infusi...

journal_title：BioMed research international

authors： Liu Y,Ye Z,Xi W,Ma T,Shi M,Yang L,Zhu Z,Zhang J

更新日期：2013-01-01 00:00:00

abstract：:Bone grafts are medical devices that are in high demand in clinical practice for substitution of bone defects and recovery of atrophic bone regions. Based on the analysis of the modern groups of bone grafts, the particularities of their composition, the mechanisms of their biological effects, and their therapeutic ind...

journal_title：BioMed research international

authors： Deev RV,Drobyshev AY,Bozo IY,Isaev AA

更新日期：2015-01-01 00:00:00

abstract：:Osteoarthritis (OA) is one of the most common debilitating disorders among the elderly population. At present, there is no definite cure for the underlying causes of OA. However, adipose tissue-derived stem cells (ADSCs) in the form of stromal vascular fraction (SVF) may offer an alternative at this time. ADSCs are on...

journal_title：BioMed research international

authors： Pak J,Lee JH,Kartolo WA,Lee SH

更新日期：2016-01-01 00:00:00

abstract：Objective:The use of a biofabrication nerve scaffold, which mimics the nerve microstructure, as an alternative for autologous nerve transplantation is a promising strategy for treating peripheral nerve defects. This study aimed to design a customized biofabrication scaffold model with the characteristics of human perip...

journal_title：BioMed research international

authors： Yao Z,Yan LW,Qiu S,He FL,Gu FB,Liu XL,Qi J,Zhu QT

更新日期：2019-12-14 00:00:00

abstract：:Purpose. To evaluate correlation between tomographic gradation of keratoconus (KC) and its corresponding air-puff induced biomechanical response. Methods. Corneal tomography and biomechanics were measured with Scheimpflug imaging in 44 normal and 92 KC corneas. Deformation waveform was also analyzed with Fourier serie...

journal_title：BioMed research international

authors： Shetty R,Nuijts RM,Srivatsa P,Jayadev C,Pahuja N,Akkali MC,Sinha Roy A

更新日期：2015-01-01 00:00:00

abstract：:Schistosomiasis, caused by infection with Schistosoma species, remains an important parasitic zoonosis. Thioredoxin glutathione reductase of Schistosoma japonicum (SjTGR) plays an important role in the development of the parasite and for its survival. Here we present a recombinant plasmid DNA vaccine, pVAX1/SjTGR, to ...

journal_title：BioMed research international

authors： Cao Y,Zhao B,Han Y,Zhang J,Li X,Qiu C,Wu X,Hong Y,Ai D,Lin J,Fu Z

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:Fusarium, Aspergillus, and Dematiaceous are the most common fungal species causing keratitis in tropical countries. Herein we report a prospective study on fungal keratitis caused by these three fungal species. METHODOLOGY:A prospective investigation was undertaken to evaluate eyes with presumed fungal keratit...

journal_title：BioMed research international

authors： Gajjar DU,Pal AK,Ghodadra BK,Vasavada AR

更新日期：2013-01-01 00:00:00

abstract：:The receptor activator of NF-κB (RANK) pathway is involved in bone health as well as breast cancer (BC) pathogenesis and progression. Whereas the therapeutic implication of this pathway is established for the treatment of osteoporosis and bone metastases, the application in adjuvant BC is currently investigated. As ge...

journal_title：BioMed research international

authors： Hein A,Bayer CM,Schrauder MG,Häberle L,Heusinger K,Strick R,Ruebner M,Lux MP,Renner SP,Schulz-Wendtland R,Ekici AB,Hartmann A,Beckmann MW,Fasching PA

更新日期：2014-01-01 00:00:00

abstract：:Electrospun scaffolds provide a dense framework of nanofibers with pore sizes and fiber diameters that closely resemble the architecture of native extracellular matrix. However, it generates limited three-dimensional structures of relevant physiological thicknesses. 3D printing allows digitally controlled fabrication ...

journal_title：BioMed research international

authors： Mellor LF,Huebner P,Cai S,Mohiti-Asli M,Taylor MA,Spang J,Shirwaiker RA,Loboa EG

更新日期：2017-01-01 00:00:00

abstract：:Age is an independent risk factor of cardiovascular disease, even in the absence of other traditional factors. Emerging evidence in experimental animal and human models has emphasized a central role for two main mechanisms of age-related cardiovascular disease: oxidative stress and inflammation. Excess reactive oxygen...

journal_title：BioMed research international

authors： Wu J,Xia S,Kalionis B,Wan W,Sun T

更新日期：2014-01-01 00:00:00