Histochemical Study of the Rat Uterine Glycoconjugate Alteration following Treatment with Exogenous Gonadotropic Hormones during the Implantation Period.

Abstract:

:One of the female causes of infertility is anovulation which is treatable with gonadotropin hormones. These hormones affect the molecular organization of the uterus such as glycoconjugates that are the first site of contact between the blastocyst and the uterus. The objective of this project was to study the alteration of glycoconjugates on the uterine apical, Golgi zone, and basement membrane of epithelial cells and the uterine gland after hyperstimulation with pregnant mare serum gonadotropin (PMSG) (4, 8, 16, 24, and 40 IU), during the implantation period. Injection of PMSG (in experimental groups) and injection of distilled water (in the control group) were followed by HCG administration (10 IU), mating, isolation of positive vaginal plug rats, and killing at 5.5 days of pregnancy. Histochemistry was done on the pregnant uterine horns with the use of WGA, DBA, PNA, ConA, SBA, and UEA lectins. The intensity of the immunohistochemical staining was scored, and quantitative data were generated. 4 IU did not show any significant differences with the control, 8 IU had less effect on the alteration of the Golgi zone, and apical and basement membrane glycoconjugates and 40 IU had the least effects on the alteration of uterine gland glycoconjugates. Also, 24 IU had the most effect on the alteration of uterine glycoconjugates. Understanding of the effects of gonadotropin hormones at the uterine level in implantation time helps to optimize hormonal manipulation for improving the outcome of assisted reproductive procedures. It seems that the optimal dose for superovulation and less alteration in uterine glycoconjugates of rats at implantation time were induced by the administration of 8 IU PMSG.

journal_name

Biomed Res Int

authors

Aliabadi E,Makoolati Z,Talaei-Khozani T,Ardekani FM,Aliabadi A

doi

10.1155/2020/3967427

subject

Has Abstract

pub_date

2020-12-04 00:00:00

pages

3967427

eissn

2314-6133

issn

2314-6141

journal_volume

2020

pub_type

杂志文章
  • Deep Response in Multiple Myeloma: A Critical Review.

    abstract::Novel and more effective treatment strategies against multiple myeloma (MM) have significantly prolonged patients' survival and raised interest in the depth of response and its association with clinical outcome. Minimal residual disease (MRD) has emerged as one of the most relevant prognostic factors in MM and should ...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2015/832049

    authors: Fulciniti M,Munshi NC,Martinez-Lopez J

    更新日期:2015-01-01 00:00:00

  • Effect of High Dietary Tryptophan on Intestinal Morphology and Tight Junction Protein of Weaned Pig.

    abstract::Tryptophan (Trp) plays an essential role in pig behavior and growth performances. However, little is known about Trp's effects on tight junction barrier and intestinal health in weaned pigs. In the present study, twenty-four (24) weaned pigs were randomly assigned to one of the three treatments with 8 piglets/treatmen...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/2912418

    authors: Tossou MC,Liu H,Bai M,Chen S,Cai Y,Duraipandiyan V,Liu H,Adebowale TO,Al-Dhabi NA,Long L,Tarique H,Oso AO,Liu G,Yin Y

    更新日期:2016-01-01 00:00:00

  • The effect of multiple single nucleotide polymorphisms in the folic acid pathway genes on homocysteine metabolism.

    abstract:OBJECTIVE:To investigate the joint effects of the single nucleotide polymorphisms (SNPs) of genes in the folic acid pathway on homocysteine (Hcy) metabolism. METHODS:Four hundred women with normal pregnancies were enrolled in this study. SNPs were identified by MassARRAY. Serum folic acid and Hcy concentration were me...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/560183

    authors: Liang S,Zhou Y,Wang H,Qian Y,Ma D,Tian W,Persaud-Sharma V,Yu C,Ren Y,Zhou S,Li X

    更新日期:2014-01-01 00:00:00

  • Effect of High Protein Diet and Probiotic Lactobacillus casei Shirota Supplementation in Aflatoxin B1-Induced Rats.

    abstract::Probiotic Lactobacillus casei Shirota (LcS) is a potential decontaminating agent of aflatoxin B1 (AFB1). However, few studies have investigated the influence of diet, especially a high protein (HP) diet, on the binding of AFB1 by probiotics. This research was conducted to determine the effect of HP diet on the ability...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/9568351

    authors: Nurul Adilah Z,Liew WP,Mohd Redzwan S,Amin I

    更新日期:2018-05-23 00:00:00

  • Multiblock discriminant analysis for integrative genomic study.

    abstract::Human diseases are abnormal medical conditions in which multiple biological components are complicatedly involved. Nevertheless, most contributions of research have been made with a single type of genetic data such as Single Nucleotide Polymorphism (SNP) or Copy Number Variation (CNV). Furthermore, epigenetic modifica...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/783592

    authors: Kang M,Kim DC,Liu C,Gao J

    更新日期:2015-01-01 00:00:00

  • Crocetin downregulates the proinflammatory cytokines in methylcholanthrene-induced rodent tumor model and inhibits COX-2 expression in cervical cancer cells.

    abstract::The effect of crocetin (C20H24O4) on methylcholanthrene- (MCA-) induced uterine cervical cancer in mice was studied in this paper. After the mice were treated orally with crocetin, maleic dialdehyde (MDA), polymorphonuclear cells (PMN), interleukin-1β (IL-1β), and tumor necrosis factor-α (TNF-α) were examined by ELISA...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/829513

    authors: Chen B,Hou ZH,Dong Z,Li CD

    更新日期:2015-01-01 00:00:00

  • Comparison of National Institutes of Health-Chronic Prostatitis Symptom Index with International Index of Erectile Function 5 in Men with Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Large Cross-Sectional Study in China.

    abstract::The purpose of the study is to evaluate the relationship between NIH-CPSI and IIEF-5 in Chinese men with CP/CPPS. A large cross-sectional and multicenter survey was conducted from July 2012 to January 2014. Men were recruited from urology clinics which were located at the five cities in China. All men participated in ...

    journal_title:BioMed research international

    pub_type: 杂志文章,多中心研究

    doi:10.1155/2015/560239

    authors: Gao J,Gao P,Hao Z,Zhou Z,Liu J,Li H,Xing J,Zhou Z,Deng C,Deng L,Wei Q,Zhang X,Zhou J,Fan S,Tai S,Yang C,Shi K,Huang Y,Ye Z,Liang C

    更新日期:2015-01-01 00:00:00

  • Mesenchymal stem cells expressing brain-derived neurotrophic factor enhance endogenous neurogenesis in an ischemic stroke model.

    abstract::Numerous studies have reported that mesenchymal stem cells (MSCs) can ameliorate neurological deficits in ischemic stroke models. Among the various hypotheses that have been suggested to explain the therapeutic mechanism underlying these observations, neurogenesis is thought to be critical. To enhance the therapeutic ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/129145

    authors: Jeong CH,Kim SM,Lim JY,Ryu CH,Jun JA,Jeun SS

    更新日期:2014-01-01 00:00:00

  • Characterization of imidazoline receptors in blood vessels for the development of antihypertensive agents.

    abstract::It has been indicated that activation of peripheral imidazoline I2-receptor (I-2R) may reduce the blood pressure in spontaneously hypertensive rats (SHRs). Also, guanidinium derivatives show the ability to activate imidazoline receptors. Thus, it is of special interest to characterize the I-2R using guanidinium deriva...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/182846

    authors: Chen MF,Tsai JT,Chen LJ,Wu TP,Yang JJ,Yin LT,Yang YL,Chiang TA,Lu HL,Wu MC

    更新日期:2014-01-01 00:00:00

  • Beta-thalassaemia intermedia: evaluation of endocrine and bone complications.

    abstract:OBJECTIVE:Data about endocrine and bone disease in nontransfusion-dependent thalassaemia (NTDT) is scanty. The aim of our study was to evaluate these complications in β-TI adult patients. METHODS:We studied retrospectively 70 β-TI patients with mean followup of 20 years. Data recorded included age, gender, haemoglobin...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/174581

    authors: Baldini M,Marcon A,Cassin R,Ulivieri FM,Spinelli D,Cappellini MD,Graziadei G

    更新日期:2014-01-01 00:00:00

  • Cloning and expression of synthetic genes encoding the broad antimicrobial spectrum bacteriocins SRCAM 602, OR-7, E-760, and L-1077, by recombinant Pichia pastoris.

    abstract::We have evaluated the cloning and functional expression of previously described broad antimicrobial spectrum bacteriocins SRCAM 602, OR-7, E-760, and L-1077, by recombinant Pichia pastoris. Synthetic genes, matching the codon usage of P. pastoris, were designed from the known mature amino acid sequence of these bacter...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/767183

    authors: Arbulu S,Jiménez JJ,Gútiez L,Cintas LM,Herranz C,Hernández PE

    更新日期:2015-01-01 00:00:00

  • Nanoscale bonding between human bone and titanium surfaces: osseohybridization.

    abstract::Until now, the chemical bonding between titanium and bone has been examined only through a few mechanical detachment tests. Therefore, in this study, a sandblasted and acid-etched titanium mini-implant was removed from a human patient after 2 months of placement in order to identify the chemical integration mechanism ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/960410

    authors: Kim JS,Kang SM,Seo KW,Nahm KY,Chung KR,Kim SH,Ahn JP

    更新日期:2015-01-01 00:00:00

  • Combined Administration of Bisphosphonates, Chemotherapeutic Agents, and/or Targeted Drugs Increases the Risk for Stage 3 Medication-Related Osteonecrosis of the Jaw: A 4-Year Retrospective Study.

    abstract:Objectives:Patients with stage 3 medication-related osteonecrosis of the jaw (MRONJ) suffer from severe complications. Chemotherapeutic agents and targeted drugs are considered to be associated with the development of MRONJ. However, little is known regarding the association of those agents with stage 3 MRONJ. The purp...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/5847429

    authors: Zhou Y,Yu Y,Shi Y,Li M,Yang C,Wang S

    更新日期:2020-10-15 00:00:00

  • Using ecological momentary assessment to evaluate current physical activity.

    abstract:OBJECTIVE:The purpose of this study was to assess the value of ecological momentary assessment in evaluating physical activity among children, adolescents, and adults. It also determines whether ecological momentary assessment fulfills the criteria of validity, reliability, objectivity, norms, and standardization appli...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2014/915172

    authors: Marszalek J,Morgulec-Adamowicz N,Rutkowska I,Kosmol A

    更新日期:2014-01-01 00:00:00

  • Detoxification Assays of Tunisian Tannery Wastewater under Nonsterile Conditions Using the Filamentous Fungus Aspergillus niger.

    abstract::The ability of Aspergillus niger strain to reduce organic and mineral pollution as well as the toxicity of two tannery wastewaters, the unhairing effluent (UE) and the final effluent (FE), taken from a local Tunisian tannery and under nonsterile conditions, was studied. Raw effluents show alkaline pH ≥11; thus experim...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/9020178

    authors: Boujelben R,Ellouze M,Sayadi S

    更新日期:2019-06-03 00:00:00

  • Switching the sphingolipid rheostat in the treatment of diabetes and cancer comorbidity from a problem to an advantage.

    abstract::Cancer and diabetes are among the most common diseases in western societies. Epidemiological studies have shown that diabetic patients have a significantly higher risk of developing a number of different types of cancers and that individuals with comorbidity (cancer and diabetes/prediabetes) have a poorer prognosis re...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2015/165105

    authors: Haass NK,Nassif N,McGowan EM

    更新日期:2015-01-01 00:00:00

  • Assessment of Corneal Pachymetry Distribution and Morphologic Changes in Subclinical Keratoconus with Normal Biomechanics.

    abstract:Purpose:To investigate the pachymetry distribution of central cornea and morphologic changes in subclinical keratoconus with normal biomechanics and determine their potential benefit for the screening of very early keratoconus. Methods:This retrospective comparative study was performed in 33 clinically unaffected eyes...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/1748579

    authors: Song P,Yang K,Li P,Liu Y,Liang D,Ren S,Zeng Q

    更新日期:2019-11-19 00:00:00

  • Pulmonary Rehabilitation Can Improve the Functional Capacity and Quality of Life for Pneumoconiosis Patients: A Systematic Review and Meta-Analysis.

    abstract::This study evaluated the efficacy and safety of pulmonary rehabilitation (PR) for pneumoconiosis. We systematically searched PubMed, Embase, The Cochrane Library, Web of Science, SinoMed, CNKI, VIP databases and Wanfang Data from their inception to June 1, 2019. A systematic review and meta-analysis of randomized cont...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2020/6174936

    authors: Zhao H,Xie Y,Wang J,Li X,Li J

    更新日期:2020-07-28 00:00:00

  • Mystery of Retinal Vein Occlusion: Vasoactivity of the Vein and Possible Involvement of Endothelin-1.

    abstract::Retinal vein occlusion (RVO) is a common vascular disease of retina; however, the pathomechanism leading to RVO is not yet clear. In general, increasing age, hypertension, arteriosclerosis, diabetes mellitus, dyslipidemia, cardiovascular disorder, and cerebral stroke are systemic risk factors of RVO. However, RVO ofte...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2017/4816527

    authors: Kida T

    更新日期:2017-01-01 00:00:00

  • Optimal Condition to Create Femoral Tunnel Considering Combined Influence of Knee Flexion and Transverse Drill Angle in Anatomical Single-Bundle ACL Reconstruction Using Medial Portal Technique: 3D Simulation Study.

    abstract::There has been no previous study using three-dimensional (3D) measurement on femoral tunnel characteristics according to the combined influence of various flexion angles of knee and transverse drill angles in single-bundle ACL reconstruction with transportal technique. The purpose of this study was to determine optima...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/2643247

    authors: Kim SH,Kim SJ,Choi CH,Kim D,Jung M

    更新日期:2018-07-17 00:00:00

  • Oxidative Stress Induced by Polymyxin E Is Involved in Rapid Killing of Paenibacillus polymyxa.

    abstract::Historically, the colistin has been thought to kill bacteria through membrane lysis. Here, we present an alternative mechanism that colistin induces rapid Paenibacillus polymyxa death through reactive oxygen species production. This significantly augments our understanding of the mechanism of colistin action, which is...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/5437139

    authors: Yu Z,Zhu Y,Qin W,Yin J,Qiu J

    更新日期:2017-01-01 00:00:00

  • Cubic and hexagonal liquid crystals as drug delivery systems.

    abstract::Lipids have been widely used as main constituents in various drug delivery systems, such as liposomes, solid lipid nanoparticles, nanostructured lipid carriers, and lipid-based lyotropic liquid crystals. Among them, lipid-based lyotropic liquid crystals have highly ordered, thermodynamically stable internal nanostruct...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2014/815981

    authors: Chen Y,Ma P,Gui S

    更新日期:2014-01-01 00:00:00

  • Animal Models of Peritoneal Dialysis: Thirty Years of Our Own Experience.

    abstract::Experimental animal models improve our understanding of technical problems in peritoneal dialysis PD, and such studies contribute to solving crucial clinical problems. We established an acute and chronic PD model in nonuremic and uremic rats. We observed that kinetics of PD in rats change as the animals are aging, and...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2015/261813

    authors: Pawlaczyk K,Baum E,Schwermer K,Hoppe K,Lindholm B,Breborowicz A

    更新日期:2015-01-01 00:00:00

  • Bacterial Extracellular DNA Production Is Associated with Outcome of Prosthetic Joint Infections.

    abstract::In a retrospective study the association of the production of extracellular DNA (eDNA) in biofilms of clinical staphylococcal isolates from 60 patients with prosthetic joint infection (PJI) and the clinical outcome were investigated. Data from a previous study on eDNA production determined in 24-hour biofilms of staph...

    journal_title:BioMed research international

    pub_type: 临床试验,杂志文章

    doi:10.1155/2018/1067413

    authors: Zatorska B,Arciola CR,Haffner N,Segagni Lusignani L,Presterl E,Diab-Elschahawi M

    更新日期:2018-10-22 00:00:00

  • Functions of the C2H2 Transcription Factor Gene thmea1 in Trichoderma harzianum under Copper Stress Based on Transcriptome Analysis.

    abstract::Trichoderma spp. are important biocontrol filamentous fungi and have tremendous potential in soil bioremediation. In our previous studies, a C2H2 type transcription factor coding gene (thmea1) was cloned from a biocontrol agent T. harzianum Th-33; the encoded sequence of thmea1 contained 3 conserved C2H2 domains with ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/8149682

    authors: Mei J,Wang L,Jiang X,Wu B,Li M

    更新日期:2018-07-18 00:00:00

  • Microscopic evaluation, molecular identification, antifungal susceptibility, and clinical outcomes in fusarium, Aspergillus and, dematiaceous keratitis.

    abstract:PURPOSE:Fusarium, Aspergillus, and Dematiaceous are the most common fungal species causing keratitis in tropical countries. Herein we report a prospective study on fungal keratitis caused by these three fungal species. METHODOLOGY:A prospective investigation was undertaken to evaluate eyes with presumed fungal keratit...

    journal_title:BioMed research international

    pub_type: 临床试验,杂志文章

    doi:10.1155/2013/605308

    authors: Gajjar DU,Pal AK,Ghodadra BK,Vasavada AR

    更新日期:2013-01-01 00:00:00

  • Microbial Community Changes in the Rhizosphere Soil of Healthy and Rusty Panax ginseng and Discovery of Pivotal Fungal Genera Associated with Rusty Roots.

    abstract::Panax ginseng Meyer, a valuable medicinal plant, is severely threatened by rusty root, a condition that greatly affects its yield and quality. Studies investigating the relationship between soil microbial community composition and rusty roots are vital for the production of high-quality ginseng. Here, high-throughput ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/8018525

    authors: Wei X,Wang X,Cao P,Gao Z,Chen AJ,Han J

    更新日期:2020-01-15 00:00:00

  • IDH1/IDH2 but not TP53 mutations predict prognosis in Bulgarian glioblastoma patients.

    abstract::Mutations in genes encoding isocitrate dehydrogenase isoforms 1 (IDH1) and 2 (IDH2) have been associated with good prognosis for patients with brain neoplasias and have been commonly found together with mutated TP53 gene. To determine the prevalence of IDH1, IDH2, and TP53 mutations and their impact on overall surviva...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/654727

    authors: Stancheva G,Goranova T,Laleva M,Kamenova M,Mitkova A,Velinov N,Poptodorov G,Mitev V,Kaneva R,Gabrovsky N

    更新日期:2014-01-01 00:00:00

  • Liver autophagy in anorexia nervosa and acute liver injury.

    abstract::Autophagy, a lysosomal catabolic pathway for long-lived proteins and damaged organelles, is crucial for cell homeostasis, and survival under stressful conditions. During starvation, autophagy is induced in numerous organisms ranging from yeast to mammals, and promotes survival by supplying nutrients and energy. In the...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2014/701064

    authors: Kheloufi M,Boulanger CM,Durand F,Rautou PE

    更新日期:2014-01-01 00:00:00

  • Single Nucleotide Polymorphisms of CBX4 and CBX7 Decrease the Risk of Hepatocellular Carcinoma.

    abstract:Background:The chromobox (CBX) proteins CBX2, CBX4, CBX6, CBX7, and CBX8, also known as Polycomb (Pc) proteins, are canonical components of the Polycomb repressive complex 1 (PRC1). Abundant evidence indicates that abnormal expression of Pc proteins is associated with a variety of tumors, but their role in the pathogen...

    journal_title:BioMed research international

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1155/2019/6436825

    authors: Tan C,Bei C,Zhu X,Zhang Y,Qin L,Tan S

    更新日期:2019-05-09 00:00:00