Impact of the 2009 (7th edition) AJCC melanoma staging system in the classification of thin cutaneous melanomas.

abstract：:Chlamydophila psittaci (C. psittaci) is a human zoonotic pathogen, which could result in severe respiratory disease. In the present study, we investigated the role and mechanism of the type III secretion system (T3SS) of C. psittaci in regulating the inflammatory response in host cells. C. psittaci-infected THP-1 cell...

journal_title：BioMed research international

authors： He QZ,Zeng HC,Huang Y,Hu YQ,Wu YM

更新日期：2015-01-01 00:00:00

abstract：:Initiation and maintenance of atrial fibrillation (AF) is often associated with pharmacologically or pathologically induced bradycardic states. Even drugs specifically developed in order to counteract cardiac arrhythmias often combine their action with bradycardia and, in turn, with development of AF, via still largel...

journal_title：BioMed research international

authors： Cacciani F,Zaniboni M

更新日期：2015-01-01 00:00:00

abstract：:Recombinant adeno-associated virus (AAV) vectors are powerful tools for both basic neuroscience experiments and clinical gene therapies for neurological diseases. Intravascularly administered self-complementary AAV9 vectors can cross the blood-brain barrier. However, AAV9 vectors are of limited usefulness because they...

journal_title：BioMed research international

authors： Iida A,Takino N,Miyauchi H,Shimazaki K,Muramatsu S

更新日期：2013-01-01 00:00:00

abstract：:We aimed to explore the effects of raloxifene (RAL) on the proliferation and apoptosis of human aortic valve interstitial cells (AVICs). Different concentrations of RAL were used to act on AVICs. MTS kit is used to test the effects of different concentrations of RAL on the proliferation of AVICs. Cell cycle and apopto...

journal_title：BioMed research international

authors： Fu Z,Luo B,Li M,Peng B,Wang Z

更新日期：2016-01-01 00:00:00

abstract：:A familiarity with the anatomy of some types of bone anomalies is necessary for clinicians involved in many medical areas. The aim of this paper is to review the newest literature concerning the morphology, embryology, clinical image, and therapeutic methods of the cervical ribs in the humans. The incidence of cervica...

journal_title：BioMed research international

authors： Spadliński Ł,Cecot T,Majos A,Stefańczyk L,Pietruszewska W,Wysiadecki G,Topol M,Polguj M

更新日期：2016-01-01 00:00:00

abstract：:In this study, we prepared PTX-loaded mesoporous hollow SnO2 nanofibers conjugated with folic acid (SFNFP) for liver cancer therapy. According to SEM and TEM characterization, SFNF showed a mesoporous hollow structure. The average outer diameter was 200 nm, and the wall thickness was 50 nm. The DSC and XRD study showe...

journal_title：BioMed research international

authors： Lv H,Wu C,Liu X,Bai A,Cao Y,Shang W,Hu L,Liu Y

更新日期：2018-11-25 00:00:00

abstract：:Human histone deacetylase 2 (HDAC2) has been identified as being associated with Alzheimer's disease (AD), a neuropathic degenerative disease. In this study, we screen the world's largest Traditional Chinese Medicine (TCM) database for natural compounds that may be useful as lead compounds in the search for inhibitors...

journal_title：BioMed research international

authors： Hung TC,Lee WY,Chen KB,Chan YC,Lee CC,Chen CY

更新日期：2014-01-01 00:00:00

abstract：:The aim of this study was to evaluate a novel composite material for tracheal reconstruction in an ovine model. A polymer containing various forms of carbon fibers (roving, woven, and nonwoven fabric) impregnated with polysulfone (PSU) was used to create cylindrical tracheal implants, 3 cm in length and 2.5 cm in diam...

journal_title：BioMed research international

authors： Ścierski W,Lisowska G,Namysłowski G,Misiołek M,Pilch J,Menaszek E,Gawlik R,Błażewicz M

更新日期：2018-10-17 00:00:00

abstract：Background:It is well known that the programmed intermittent epidural bolus (PIEB) technique effectively provides epidural anesthesia in labor. This randomized double-blind trial compared the postoperative analgesic efficacy of PIEB with that of continuous epidural infusion (CEI) in patients undergoing gynecological su...

journal_title：BioMed research international

authors： Satomi S,Kakuta N,Murakami C,Sakai Y,Tanaka K,Tsutsumi YM

更新日期：2018-05-15 00:00:00

abstract：:Acute leukemias are the most frequent childhood malignancies worldwide and remain a leading cause of morbidity and mortality of relapsed patients. While remarkable progress has been made in characterizing genetic aberrations that may control these hematological disorders, it has also become clear that abnormalities in...

journal_title：BioMed research international

authors： Dorantes-Acosta E,Vadillo E,Contreras-Quiroz A,Balandrán JC,Arriaga-Pizano L,Purizaca J,Huerta-Yepez S,Jiménez E,Aguilera W,Medina-Sanson A,Mayani H,Pelayo R

更新日期：2013-01-01 00:00:00

abstract：:Owing to its hydrophilicity, negative charge, small size, and labile degradation by endogenous nucleases, small interfering RNA (siRNA) delivery must be achieved by a carrier system. In this study, cationic copolymers composed of low-molecular-weight polyethylenimine and polythiophenes were synthesized and evaluated a...

journal_title：BioMed research international

authors： He P,Hagiwara K,Chong H,Yu HH,Ito Y

更新日期：2015-01-01 00:00:00

abstract：:Stress shielding and micromotion are two major issues which determine the success of newly designed cementless femoral stems. The correlation of experimental validation with finite element analysis (FEA) is commonly used to evaluate the stress distribution and fixation stability of the stem within the femoral canal. T...

journal_title：BioMed research international

authors： Baharuddin MY,Salleh ShH,Hamedi M,Zulkifly AH,Lee MH,Mohd Noor A,Harris AR,Abdul Majid N

更新日期：2014-01-01 00:00:00

abstract：:Autophagic elements typically appear as spherical bodies. During their life they undergo a series of changes (e.g., fusion, degradation of content, and swelling) which influence their size in a way that may be characteristic for cell type, stage of maturation, or various experimentally manipulated parameters. A simple...

journal_title：BioMed research international

authors： Kovács AL

更新日期：2014-01-01 00:00:00

abstract：:Following cerebral ischemia/reperfusion (I/R) injury, a series of pathophysiological processes are stimulated in both the central nervous system (CNS) and the periphery, including, but not limited to, the peripheral immune and endocrine systems and underregulation of the neuroendocrine-immune network. Glutamate (Glu) ...

journal_title：BioMed research international

authors： You J,Feng L,Xin M,Ma D,Feng J

更新日期：2018-07-19 00:00:00

abstract：:Stimuli responsive pH- and temperature-sensitive hydrogel drug delivery systems, as those based on N-isopropylacrylamide (NiPAAm) and itaconic acid (IA), have been attracting much of the attention of the scientific community nowadays, especially in the field of drug release. By adjusting comonomer composition, the mat...

journal_title：BioMed research international

authors： Milašinović N,Knežević-Jugović Z,Milosavljević N,Lučić Škorić M,Filipović J,Kalagasidis Krušić M

更新日期：2014-01-01 00:00:00

abstract：:Background. There has been a decline in emphasis of the value of physical examination in heart failure (HF) with increased reliance on cardiac imaging. We aim to study the clinical and prognostic significance of positive hepatojugular reflux (HJR) on discharge in patients hospitalized with HF. Methods. Using the ESCAP...

journal_title：BioMed research international

authors： Omar HR,Guglin M

更新日期：2017-01-01 00:00:00

abstract：:Bacterial quorum sensing (QS) is a cell-to-cell communication in which specific signals are activated to coordinate pathogenic behaviors and help bacteria acclimatize to the disadvantages. The QS signals in the bacteria mainly consist of acyl-homoserine lactone, autoinducing peptide, and autoinducer-2. QS signaling ac...

journal_title：BioMed research international

authors： Jiang Q,Chen J,Yang C,Yin Y,Yao K

更新日期：2019-04-04 00:00:00

abstract：Introduction:We investigated the proportion of myeloid-derived suppressor cells (MDSCs) and their subsets in patients with rheumatic diseases and clarified the association between these cells and the patient clinical data. Methods:Patients with rheumatic diseases and healthy controls were recruited. The clinical chara...

journal_title：BioMed research international

authors： Zhu J,Chen S,Wu L,Wang R,Zheng S,Zhao D,Wang X,Li J

更新日期：2018-06-26 00:00:00

abstract：BACKGROUND:We performed a retrospective study to assess whether the initial molecular characteristics of glioblastomas (GBMs) were associated with the response to the bevacizumab/irinotecan chemotherapy regimen given at recurrence. RESULTS:Comparison of the genomic and gene expression profiles of the responders (n = 1...

journal_title：BioMed research international

authors： Laffaire J,Di Stefano AL,Chinot O,Idbaih A,Gallego Perez-Larraya J,Marie Y,Vintonenko N,Boisselier B,Farina P,Delattre JY,Figarella-Branger D,Honnorat J,Sanson M,Ducray F

更新日期：2014-01-01 00:00:00

abstract：:Introduction. The triangular fibrocartilage complex (TFCC) provides both mobility and stability of the radiocarpal joint. TFCC lesions are difficult to diagnose due to the complex anatomy. The standard treatment for TFCC lesions is arthroscopy, posing surgery-related risks onto the patients. This feasibility study aim...

journal_title：BioMed research international

authors： Hammer N,Hirschfeld U,Strunz H,Werner M,Wolfskämpf T,Löffler S

更新日期：2017-01-01 00:00:00

abstract：:Three bioactive fractions, extracellular laccase (ex-LAC), crude endopolysaccharides (c-EPL), and a low molecular subfraction of secondary metabolites (ex-LMS), were isolated from the idiophasic cultures of the white rot fungus Cerrena unicolor. For the first time, we determined the antioxidant properties of these sam...

journal_title：BioMed research international

authors： Jaszek M,Osińska-Jaroszuk M,Janusz G,Matuszewska A,Stefaniuk D,Sulej J,Polak J,Ruminowicz M,Grzywnowicz K,Jarosz-Wilkołazka A

更新日期：2013-01-01 00:00:00

abstract：:Mycobacterium bovis causes classic bovine tuberculosis, a zoonosis which is still a concern in Africa. Biofilm forming ability of two Mycobacterium bovis strains was assessed on coupons of cement, ceramic, or stainless steel in three different microbiological media at 37°C with agitation for 2, 3, or 4 weeks to determ...

journal_title：BioMed research international

authors： Adetunji VO,Kehinde AO,Bolatito OK,Chen J

更新日期：2014-01-01 00:00:00

abstract：:The insula is believed to be associated with touch-evoked effects. In this work, functional MRI was applied to investigate the network model of insula function when 20 normal subjects received tactile stimulation over segregated areas. Data analysis was performed with SPM8 and Conn toolbox. Activations in the contrala...

journal_title：BioMed research international

authors： Wei P,Bao R

更新日期：2013-01-01 00:00:00

abstract：:Bacterial infections are the most common cause of purulent soft tissue inflammations in the head and neck area. These bacteria are also responsible for the majority of inflammatory complications after third molar removal. The key to success of antibacterial treatment in both cases is the use of an appropriate antibact...

journal_title：BioMed research international

authors： Bogacz M,Morawiec T,Śmieszek-Wilczewska J,Janowska-Bogacz K,Bubiłek-Bogacz A,Rój R,Pinocy K,Mertas A

更新日期：2019-10-07 00:00:00

abstract：Background:The use of modern family planning methods among women of reproductive age (15-49 years) is of public health importance in Ethiopia. Nationally, modern family planning method use remains as low as 35%. Understanding factors associated with the use of modern family planning methods may help to improve maternal...

journal_title：BioMed research international

authors： Mulatu T,Sintayehu Y,Dessie Y,Deressa M

更新日期：2020-12-29 00:00:00

abstract：:The ability of Aspergillus niger strain to reduce organic and mineral pollution as well as the toxicity of two tannery wastewaters, the unhairing effluent (UE) and the final effluent (FE), taken from a local Tunisian tannery and under nonsterile conditions, was studied. Raw effluents show alkaline pH ≥11; thus experim...

journal_title：BioMed research international

authors： Boujelben R,Ellouze M,Sayadi S

更新日期：2019-06-03 00:00:00

abstract：:Modern orthopaedic surgery provides a variety of techniques for cartilage repair. The Autologous Matrix-Induced Chondrogenesis (AMIC) procedure is a single-step technique with a collagen I/III scaffold for the treatment of full-thickness cartilage lesions. The aim of the study was to analyze the outcome of the AMIC pr...

journal_title：BioMed research international

authors： Lahner M,Ull C,Hagen M,von Schulze Pellengahr C,Daniilidis K,von Engelhardt LV,Lahner N,Teske W

更新日期：2018-05-08 00:00:00

abstract：Background:Glucagon-like peptide 1 (GLP-1) hormone is an incretin hormone that is secreted in the ileum and plays a role in the pancreas to increase insulin secretion, stimulate proliferation, and prevent pancreatic β-cell apoptosis. Currently, diabetes mellitus (DM) treatment based on GLP-1 work is being developed, fo...

journal_title：BioMed research international

authors： Kartinah NT,Fadilah F,Ibrahim EI,Suryati Y

更新日期：2019-11-11 00:00:00

abstract：Background:Acute heart failure (AHF) is associated with disturbances of the peripheral perfusion leading to the dysfunction of many organs. Consequently, an episode of AHF constitutes a "multiple organ failure" which may also affect the skeletal muscles. However, the abnormalities within skeletal muscles during AHF hav...

journal_title：BioMed research international

authors： Węgrzynowska-Teodorczyk K,Siennicka A,Josiak K,Zymliński R,Kasztura M,Banasiak W,Ponikowski P,Woźniewski M

更新日期：2018-03-12 00:00:00

abstract：:Mucosal melanoma is a rare disease, which differs from its cutaneous counterpart genetically and for its clinical behaviour. Moreover this is a heterogeneous disease based on the tissue of origin. As CT7 and CT10 are highly expressed in cutaneous melanoma and are immunogenic in this disease, we analysed their expressi...

journal_title：BioMed research international

authors： Curioni-Fontecedro A,Pitocco R,Schoenewolf NL,Holzmann D,Soldini D,Dummer R,Calvieri S,Moch H,Mihic-Probst D,Fitsche A

更新日期：2015-01-01 00:00:00