TLR stimulation of bone marrow lymphoid precursors from childhood acute leukemia modifies their differentiation potentials.

abstract：:In vitro studies reveal that androgens, oestrogens, and their metabolites play a crucial role in prostate homeostasis. Most of the studies evaluated intraprostatic hormone metabolism using cell lines or preprocessed specimens. Using an ex vivo model of intact tissue cultures with preserved architecture, we characteriz...

journal_title：BioMed research international

authors： Gianfrilli D,Pierotti S,Pofi R,Leonardo C,Ciccariello M,Barbagallo F

更新日期：2014-01-01 00:00:00

abstract：:Since proteins carry out their functions through interactions with other molecules, accurately identifying the protein-ligand binding site plays an important role in protein functional annotation and rational drug discovery. In the past two decades, a lot of algorithms were present to predict the protein-ligand bindin...

journal_title：BioMed research international

authors： Wang K,Gao J,Shen S,Tuszynski JA,Ruan J,Hu G

更新日期：2013-01-01 00:00:00

abstract：:Significant positive effects, particularly on psychological state in patients who completed the follow-up pulmonary rehabilitation programs, are indicated by a large number of studies. Yet, a remarkable proportion of selected patients drop out from these programs. In this study, we investigated existing differences on...

journal_title：BioMed research international

authors： Tselebis A,Kosmas E,Bratis D,Pachi A,Ilias I,Harikiopoulou M,Theodorakopoulou E,Velentzas K,Dumitru S,Moussas G,Siafakas N,Tzanakis N

更新日期：2014-01-01 00:00:00

abstract：:Cumulative evidence has indicated that there is an important role for adult hippocampal neurogenesis in cognitive function. With the increasing prevalence of cognitive decline associated with neurodegenerative diseases among the ageing population, physical exercise, a potent enhancer of adult hippocampal neurogenesis,...

journal_title：BioMed research international

authors： Yau SY,Gil-Mohapel J,Christie BR,So KF

更新日期：2014-01-01 00:00:00

abstract：:The potential of three submerged aquatic plant species (Cabomba piauhyensis, Egeria densa, and Hydrilla verticillata) to be used for As, Al, and Zn phytoremediation was tested. The plants were exposed for 14 days under hydroponic conditions to mine waste water effluents in order to assess the suitability of the aquati...

journal_title：BioMed research international

authors： Abu Bakar AF,Yusoff I,Fatt NT,Othman F,Ashraf MA

更新日期：2013-01-01 00:00:00

abstract：:Neurotrophic keratitis (NK) is a rare degenerative disease of the cornea caused by an impairment of corneal sensory innervation, characterized by decreased or absent corneal sensitivity resulting in epithelial keratopathy, ulceration, and perforation. The aetiopathogenesis of corneal sensory innervation impairment in ...

journal_title：BioMed research international

authors： Mantelli F,Nardella C,Tiberi E,Sacchetti M,Bruscolini A,Lambiase A

更新日期：2015-01-01 00:00:00

abstract：:Bloodstream infections are a major concern because of high levels of antibiotic consumption and of the increasing prevalence of antimicrobial resistance. Bacteraemia is identified in a small percentage of patients with signs and symptoms of sepsis. Biomarkers are widely used in clinical practice and they are useful fo...

journal_title：BioMed research international

authors： Henriquez-Camacho C,Losa J

更新日期：2014-01-01 00:00:00

abstract：:Cardiotonic drugs mainly include digitalis, catecholamines, phosphodiesterase inhibitors, and calcium sensitizers, which have been successively discovered and applied in clinical practice. However, there are only a few new drugs available in this field, and the selection is very limited. Digitalis, catecholamines, and...

journal_title：BioMed research international

authors： Pan J,Yang YM,Zhu JY,Lu YQ

更新日期：2019-09-19 00:00:00

abstract：:Background. Monitoring the epidemiology of cardiovascular risk factors (CRFs) and their determinants is important to develop appropriate recommendations to prevent cardiovascular diseases in specific risk groups. The NESCaV study was designed to collect standardized data to estimate the prevalence of CRFs in relation ...

journal_title：BioMed research international

authors： Streel S,Donneau AF,Hoge A,Majerus S,Kolh P,Chapelle JP,Albert A,Guillaume M

更新日期：2015-01-01 00:00:00

abstract：Introduction:Retinol Binding Protein 4 (RBP4) is mainly excreted by the kidney and plays a pivotal role in insulin resistance (IR). In our study, we evaluated the association between RBP4 and IR in hemodialysis subjects (HD). We also assessed how circulating RBP4 could be influenced by kidney transplant or different di...

journal_title：BioMed research international

authors： Grosjean F,Esposito P,Maccarrone R,Libetta C,Dal Canton A,Rampino T

更新日期：2017-01-01 00:00:00

abstract：:This study presented the analysis of free-breathing lung tumor motion characteristics using GE 4DCT and Varian RPM systems. Tumor respiratory movement was found to be associated with GTV size, the superior-inferior tumor location in the lung, and the attachment degree to rigid structure (e.g., chest wall, vertebrae, o...

journal_title：BioMed research international

authors： Wang Y,Bao Y,Zhang L,Fan W,He H,Sun ZW,Hu X,Huang SM,Chen M,Deng XW

更新日期：2013-01-01 00:00:00

abstract：Purpose:To explore the effects of depression on cardiac autonomic nerve function and related metabolic pathways, the heart rate variability (HRV) and urinary differential metabolites were detected on the college students with depression. Methods:12 female freshmen with depression were filtered by the Beck Depression I...

journal_title：BioMed research international

authors： Zhao S,Chi A,Yan J,Yao C

更新日期：2020-02-27 00:00:00

abstract：:Red blood cell distribution width (RDW) is a parameter reported in complete blood cell count tests, and has been reported as an inflammatory biomarker. Multiple myeloma (MM) is known to be associated with inflammatory microenvironments. However, the importance of RDW has been seldom studied in MM. For this study, 146 ...

journal_title：BioMed research international

authors： Lee H,Kong SY,Sohn JY,Shim H,Youn HS,Lee S,Kim HJ,Eom HS

更新日期：2014-01-01 00:00:00

abstract：Background:To improve the efficacy of regenerative treatment for gingival recessions, the autologous platelet concentrates (APCs) combined with coronally advanced flap (CAF) have been investigated. However, few studies systematically assess the complementary effect of APCs in periodontal regeneration. The present study...

journal_title：BioMed research international

authors： Li R,Liu Y,Xu T,Zhao H,Hou J,Wu Y,Zhang D

更新日期：2019-07-25 00:00:00

abstract：:Nitric oxide (NO) has a wide variety of physiological functions in the kidney. Besides the regulatory effects in intrarenal haemodynamics and glomerular microcirculation, in vivo studies reported the diuretic and natriuretic effects of NO. However, opposite results showing the stimulatory effect of NO on Na+ reabsorpt...

journal_title：BioMed research international

authors： Satoh N,Nakamura M,Suzuki A,Tsukada H,Horita S,Suzuki M,Moriya K,Seki G

更新日期：2017-01-01 00:00:00

abstract：:The present study was conducted to evaluate the effect of a Bacillus megaterium-coated diet on growth performance, digestive enzymes, and intestinal microbial diversity in Songpu mirror carp (Cyprinus specularis Songpu). The fish were manually fed two diets (a control diet and a B. megaterium-coated diet) three times ...

journal_title：BioMed research international

authors： Luo L,Xu Q,Xu W,Li J,Wang C,Wang L,Zhao Z

更新日期：2020-11-13 00:00:00

abstract：OBJECTIVE:Conventional surgical techniques of laryngomicrosurgery (LMS) on hemorrhagic vocal polyps are often difficult due to obscuration of the surgical field by inadvertent bleeding from the lesion, and there are often significant amounts of mucosal epithelium loss. Here, we introduce our surgical technique using pu...

journal_title：BioMed research international

authors： Byeon HK,Han JH,Choi BI,Hwang HJ,Kim JH,Choi HS

更新日期：2015-01-01 00:00:00

abstract：Objective:To assess the application value of perfusion-weighted imaging (PWI) in early diagnosis, quantitation, and hepatic fibrosis staging by analyzing the related parameters in hepatic fibrosis. Methods:A total of 60 rats were randomly divided into the hepatic fibrosis and control groups, and carbon tetrachloride (...

journal_title：BioMed research international

authors： Fan G,Ya Y,Ni X,Hou J,Yu R

更新日期：2019-12-28 00:00:00

abstract：Background:Reduced baroreflex sensitivity (BRS) has been reported in patients with acute cardiovascular events. We tested the hypothesis that BRS varies in different subtypes of acute ischemic stroke (AIS) and that BRS is a predictor of clinical outcomes. Methods:We examined autonomic parameters in 34 patients with AI...

journal_title：BioMed research international

authors： Tsai WC,Lin HC,Lai YR,Hsu CW,Huang CC,Wang HC,Su CM,Su YJ,Lin WC,Cheng BC,Chang WN,Lu CH,Tsai NW

更新日期：2019-04-18 00:00:00

abstract：Objectives:To evaluate the role of short-term low-dose glucocorticoids in mild COVID-19 patients. Methods:We conducted a retrospective, cross-sectional, single-center study in Kunming, China. A total of 33 mild COVID-19 cases were divided into two treatment groups (with and without glucocorticoids, methylprednisolone,...

journal_title：BioMed research international

authors： Fu HY,Luo Y,Gao JP,Wang L,Li HJ,Li X,Xue L,Tang XQ,Li HW,Du YR

更新日期：2020-09-23 00:00:00

abstract：:Since 2009 pandemic, international health authorities recommended monitoring severe and complicated cases of respiratory disease, that is, severe acute respiratory infection (SARI) and acute respiratory distress syndrome (ARDS). We evaluated the proportion of SARI/ARDS cases and deaths due to influenza A(H1N1)pdm09 in...

journal_title：BioMed research international

authors： Pariani E,Martinelli M,Canuti M,Jazaeri Farsani SM,Oude Munnink BB,Deijs M,Tanzi E,Zanetti A,van der Hoek L,Amendola A

更新日期：2014-01-01 00:00:00

abstract：:Polyetheretherketone (PEEK), which has biomechanical performance similar to that of human cancellous bone, is used widely as a spinal implant material. However, its bioinertness and hydrophobic surface properties result in poor osseointegration. This study applies a novel modification method, arc ion plating (AIP), th...

journal_title：BioMed research international

authors： Tsou HK,Chi MH,Hung YW,Chung CJ,He JL

更新日期：2015-01-01 00:00:00

abstract：:Ampelopsis brevipedunculata (Maxim.) Trautv. (AB), a traditional East Asian medicine, exhibits protective effects against several inflammatory diseases. Our search for an inhibitor of IL-6-induced JAK2/STAT3 activation revealed that AB ethanolic extract (ABE) had a significant inhibitory effect on IL-6-induced STAT3 e...

journal_title：BioMed research international

authors： Jang HJ,Lee SJ,Lim HJ,Jung K,Lee S,Park CS,Lee SW,Rho MC

更新日期：2018-06-10 00:00:00

abstract：:The palmaris longus is considered a phylogenetic degenerate metacarpophalangeal joint flexor muscle in humans, a small vestigial forearm muscle; it is the most variable muscle in humans, showing variation in position, duplication, slips and could be reverted. It is frequently studied in papers about human anatomical v...

journal_title：BioMed research international

authors： Aversi-Ferreira RA,Bretas RV,Maior RS,Davaasuren M,Paraguassú-Chaves CA,Nishijo H,Aversi-Ferreira TA

更新日期：2014-01-01 00:00:00

abstract：:Chromosome/DNA instability could be one of the primary causes of malignant cell transformation. The objective of the present study was to evaluate the spontaneous genetic damages in exfoliated cells of buccal mucosa of head and neck cancer (HNC) by counting micronucleus (MN) and binucleated (BN) cells frequencies. MN ...

journal_title：BioMed research international

authors： Khlifi R,Trabelsi-Ksibi F,Chakroun A,Rebai A,Hamza-Chaffai A

更新日期：2013-01-01 00:00:00

abstract：:Cystic echinococcosis is a serious zoonotic disease caused by Echinococcus granulosus species complex. The current study is the first attempt to determine the level of infection in domestic livestock and to explore the CE-related knowledge and awareness among livestock farmers in different districts of Khyber Pakhtunk...

journal_title：BioMed research international

authors： Haleem S,Niaz S,Qureshi NA,Ullah R,Alsaid MS,Alqahtani AS,Shahat AA

更新日期：2018-09-12 00:00:00

abstract：:Increasing consumption of tobacco and alcohol has led to a steady increase in the incidence of head and neck cancers in Asia. The drawbacks associated with the existing chemotherapeutic and surgical interventions have necessitated the development of a safer alternative for therapy of head and neck cancers. In this stu...

journal_title：BioMed research international

authors： Mohan A,Narayanan S,Sethuraman S,Krishnan UM

更新日期：2014-01-01 00:00:00

abstract：:Here we wanted to investigate predictive value of neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR) in the diagnosis of brucellosis. Thirty-two brucellosis patients diagnosed with positive serum agglutination test and thirty-two randomized healthy subjects were enrolled in this study retrospectivel...

journal_title：BioMed research international

authors： Olt S,Ergenç H,Açıkgöz SB

更新日期：2015-01-01 00:00:00

abstract：:The endoscopic and histopathological findings detected in Sparus aurata experimentally infected with third-stage Anisakis larvae without intermediate host are evaluated and discussed. In six fish, live nematode larvae were introduced by gastroscopy into the stomach. The first observation by endoscope, 15 days after ch...

journal_title：BioMed research international

authors： Marino F,Lanteri G,Passantino A,De Stefano C,Costa A,Gaglio G,Macrì F

更新日期：2013-01-01 00:00:00

abstract：:Biolasol is a newly developed solution for storing the liver, pancreas, kidneys, and heart by simple hypothermia. It exhibits high efficacy in maintaining structural and functional integrity of the graft prior to its transplantation. The solution was modified by the addition of ascorbic acid (0.088g/l) and ascorbic ac...

journal_title：BioMed research international

authors： Ostróżka-Cieślik A,Dolińska B,Ryszka F

更新日期：2018-11-12 00:00:00