Abstract：
:A rapidly growing body of experimental evidence has begun to shed light on the wide ranging molecular mechanisms which modulate intra- and inter-cellular communications. A substantial quantity of the available knowledge has only been uncovered in recent years, and we are learning that donor cells release nanovesicles, known as exosomes, which regulate the cellular behavior of recipient cells following uptake. Based on the impressive capacity of exosomes in delivering their "payload", different therapeutic agents, are currently being tested using this delivery method for more effective therapy. This review summarizes the most recent developments in exosome bioactivities and discusses the biochemical nature of exosomes and their biogenesis. It also summarizes the use of exosomes as delivery vehicles for drugs and natural compounds to the targeted site.
journal_name
Biotechnol Advjournal_title
Biotechnology advancesauthors
Farooqi AA,Desai NN,Qureshi MZ,Librelotto DRN,Gasparri ML,Bishayee A,Nabavi SM,Curti V,Daglia Mdoi
10.1016/j.biotechadv.2017.12.010subject
Has Abstractpub_date
2018-01-01 00:00:00pages
328-334issue
1eissn
0734-9750issn
1873-1899pii
S0734-9750(17)30162-3journal_volume
36pub_type
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