Abstract：
:Heart valve tissue engineering could be a possible solution for the limitations of mechanical and biological prostheses, which are commonly used for heart valve replacement. In tissue engineering, cells are seeded into a 3-dimensional platform, termed the scaffold, to make the engineered tissue construct. However, mimicking the mechanical and spatial heterogeneity of a heart valve structure in a fabricated scaffold with uniform cell distribution is daunting when approached conventionally. Bioprinting is an emerging technique that can produce biological products containing matrix and cells, together or separately with morphological, structural and mechanical diversity. This advance increases the possibility of fabricating the structure of a heart valve in vitro and using it as a functional tissue construct for implantation. This review describes the use of bioprinting technology in heart valve tissue engineering.
journal_name
Biotechnol Advjournal_title
Biotechnology advancesauthors
Jana S,Lerman Adoi
10.1016/j.biotechadv.2015.07.006subject
Has Abstractpub_date
2015-12-01 00:00:00pages
1503-21issue
8eissn
0734-9750issn
1873-1899pii
S0734-9750(15)30019-7journal_volume
33pub_type
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