Abstract：
:Polyamines (PAs) are ubiquitous biogenic amines that have been implicated in diverse cellular functions in widely distributed organisms. In plants, mutant and transgenic plants with altered activity pointed to their involvement with different abiotic and biotic stresses. Furthermore, microarray, transcriptomic and proteomic approaches have elucidated key functions of different PAs in signaling networks in plants subjected to abiotic and biotic stresses, however the exact molecular mechanism remains enigmatic. Here, we argue that PAs should not be taken only as a protective molecule but rather like a double-faced molecule that likely serves as a major area for further research efforts. This review summarizes recent advances in plant polyamine research ranging from transgenic and mutant characterization to potential mechanisms of action during environmental stresses and diseases.
journal_name
Biotechnol Advjournal_title
Biotechnology advancesauthors
Hussain SS,Ali M,Ahmad M,Siddique KHdoi
10.1016/j.biotechadv.2011.01.003subject
Has Abstractpub_date
2011-05-01 00:00:00pages
300-11issue
3eissn
0734-9750issn
1873-1899pii
S0734-9750(11)00004-8journal_volume
29pub_type
杂志文章,评审abstract：:Product inhibition of cellulolytic enzymes affects the efficiency of the biocatalytic conversion of lignocellulosic biomass to ethanol and other valuable products. New strategies that focus on reactor designs encompassing product removal, notably glucose removal, during enzymatic cellulose conversion are required for ...
journal_title：Biotechnology advances
pub_type： 杂志文章
doi：10.1016/j.biotechadv.2010.02.005
更新日期：2010-05-01 00:00:00
abstract：:There is considerable interest in recent years in the bioconversion of forestry and agricultural residues into ethanol and value-added chemicals. High ethanol yields from lignocellulosic residues are dependent on efficient use of all the available sugars including glucose and xylose. The well-known fermentative yeast ...
journal_title：Biotechnology advances
pub_type： 杂志文章,评审
doi：10.1016/j.biotechadv.2007.04.001
更新日期：2007-09-01 00:00:00
abstract：:Cryptosporidium parvum is an obligate protozoan parasite responsible for the diarrheal illness cryptosporidiosis in humans and animals. Although C. parvum is particularly pathogenic in immunocompromised hosts, the molecular mechanisms by which C. parvum invades the host epithelial cells are not well understood. Charac...
journal_title：Biotechnology advances
pub_type： 杂志文章,评审
doi：10.1016/j.biotechadv.2006.08.003
更新日期：2007-01-01 00:00:00
abstract：:Aerobic granular sludge sequencing batch reactors (SBR) are a promising technology for treating wastewater. Increasing evidence suggests that aerobic granulation in SBRs is driven by selection pressures exerted on microorganisms. Three major selection pressures have been identified as follows: settling time, volume ex...
journal_title：Biotechnology advances
pub_type： 杂志文章,评审
doi：10.1016/j.biotechadv.2005.04.001
更新日期：2005-07-01 00:00:00
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journal_title：Biotechnology advances
pub_type： 杂志文章
doi：10.1016/0734-9750(93)90411-f
更新日期：1993-01-01 00:00:00
abstract：:Small molecule metabolites secreted by pathological processes can act as molecular biomarkers for clinical diagnosis. In vitro detection of the metabolites such as glucose and reactive oxygen species is of great significance for precise screening, monitoring and prognosis of metabolic disorders and relevant diseases s...
journal_title：Biotechnology advances
pub_type： 杂志文章,评审
doi：10.1016/j.biotechadv.2016.01.006
更新日期：2016-05-01 00:00:00
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journal_title：Biotechnology advances
pub_type： 杂志文章,评审
doi：10.1016/j.biotechadv.2012.03.006
更新日期：2012-11-01 00:00:00
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journal_title：Biotechnology advances
pub_type： 杂志文章,评审
doi：10.1016/j.biotechadv.2019.05.001
更新日期：2019-11-01 00:00:00
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journal_title：Biotechnology advances
pub_type： 杂志文章
doi：10.1016/j.biotechadv.2010.05.019
更新日期：2010-11-01 00:00:00
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journal_title：Biotechnology advances
pub_type： 杂志文章,评审
doi：10.1016/j.biotechadv.2019.04.010
更新日期：2019-11-01 00:00:00
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journal_title：Biotechnology advances
pub_type： 杂志文章
doi：10.1016/0734-9750(91)90733-c
更新日期：1991-01-01 00:00:00
abstract：:Liquid formulation of therapeutic proteins is a maturing technology. Demand for products that are easy to use in the clinic or that are amenable to self-administration make a ready to use liquid formulation desirable. Most modern liquid formulations have a simple composition; comprising a buffer, a tonicity modifier, ...
journal_title：Biotechnology advances
pub_type： 杂志文章,评审
doi：10.1016/j.biotechadv.2019.06.011
更新日期：2019-11-15 00:00:00
abstract：:Over the past decade, L-homophenylalanine is extensively used in the pharmaceutical industry as a precursor for production of angiotensin-converting enzyme (ACE) inhibitor, which possesses significant clinical application in the management of hypertension and congestive heart failure (CHF). A number of chemical method...
journal_title：Biotechnology advances
pub_type： 杂志文章,评审
doi：10.1016/j.biotechadv.2009.01.003
更新日期：2009-05-01 00:00:00
abstract：:The world population now is 6.7 billion and is predicted to reach 9 billion by 2050. Such a rapid growing population has tremendously increased the challenge for food security. Obviously, it is impossible for traditional agriculture to ensure the food security, while plant biotechnology offers considerable potential t...
journal_title：Biotechnology advances
pub_type： 杂志文章,评审
doi：10.1016/j.biotechadv.2011.10.008
更新日期：2012-05-01 00:00:00
abstract：:Medicinal plants have historically proven their value as a source of molecules with therapeutic potential, and nowadays still represent an important pool for the identification of novel drug leads. In the past decades, pharmaceutical industry focused mainly on libraries of synthetic compounds as drug discovery source....
journal_title：Biotechnology advances
pub_type： 杂志文章,评审
doi：10.1016/j.biotechadv.2015.08.001
更新日期：2015-12-01 00:00:00
abstract：:Recently, United States Food and Drug Administration (FDA) and European Commission (EC) approved Alnylam Pharmaceuticals' RNA interference (RNAi) therapeutic, ONPATTRO™ (Patisiran), for the treatment of the polyneuropathy of hereditary transthyretin-mediated (hATTR) amyloidosis in adults. This is the first RNAi therap...
journal_title：Biotechnology advances
pub_type： 杂志文章,评审
doi：10.1016/j.biotechadv.2019.04.012
更新日期：2019-01-01 00:00:00
abstract：:Direct interspecies electron transfer (DIET) via electrically conductive pili (e-pili) and c-type cytochrome between acetogens and methanogens has been proposed as an essential pathway for methane production. Supplements of conductive materials have been extensively found to promote methane production in microbial ana...
journal_title：Biotechnology advances
pub_type： 杂志文章,评审
doi：10.1016/j.biotechadv.2019.107443
更新日期：2019-12-01 00:00:00
abstract：:Ribosomally synthesized peptides with antimicrobial properties (antimicrobial peptides-AMPs) are produced by eukaryotes and prokaryotes and represent crucial components of their defense systems against microorganisms. Although they differ in structure, they are nearly all cationic and very often amphiphilic, which ref...
journal_title：Biotechnology advances
pub_type： 杂志文章,评审
doi：10.1016/s0734-9750(03)00077-6
更新日期：2003-09-01 00:00:00
abstract：:The non-conventional oleaginous yeast Yarrowia lipolytica shows great industrial promise. It naturally produces certain compounds of interest but can also artificially generate non-native metabolites, thanks to an engineering process made possible by the significant expansion of a dedicated genetic toolbox. In this re...
journal_title：Biotechnology advances
pub_type： 杂志文章,评审
doi：10.1016/j.biotechadv.2018.10.004
更新日期：2018-12-01 00:00:00
abstract：:An increasing number of proteins are currently available on the market as therapeutics and this branch of the pharmaceutical industry will expand substantially during the coming years. As many diseases result from dysfunction of proteins forming multicomponent complexes, protein drugs with their inherent high specific...
journal_title：Biotechnology advances
pub_type： 杂志文章,评审
doi：10.1016/j.biotechadv.2011.03.005
更新日期：2011-07-01 00:00:00
abstract：:This work reviews applications of high added value molecules produced from microalgae. Older forms of valorization - health food and quality feed, polyunsaturated fatty acids, pigments, carbohydrates - are currently penetrating their markets. They are driven by desirable properties: texturer and dye for food industry,...
journal_title：Biotechnology advances
pub_type： 杂志文章,评审
doi：10.1016/j.biotechadv.2020.107545
更新日期：2020-01-01 00:00:00
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journal_title：Biotechnology advances
pub_type： 杂志文章,评审
doi：10.1016/j.biotechadv.2006.01.004
更新日期：2006-07-01 00:00:00
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journal_title：Biotechnology advances
pub_type： 杂志文章
doi：10.1016/s0734-9750(02)00015-0
更新日期：2002-11-01 00:00:00
abstract：:Hydrolysis of the whey protein alpha-lactalbumin with a specific serine protease has been shown to result in regular nanotubes of approximately 20 nm in outer diameter and reaching several mum in length. Tubular assembly depends on the concentration of protein as this determines how far the hydrolysis proceeds. A conc...
journal_title：Biotechnology advances
pub_type： 杂志文章,评审
doi：10.1016/j.biotechadv.2007.07.006
更新日期：2007-11-01 00:00:00
abstract：:Porous aluminum oxide (PAO) is a ceramic formed by an anodization process of pure aluminum that enables the controllable assembly of exceptionally dense and regular nanopores in a planar membrane. As a consequence, PAO has a high porosity, nanopores with high aspect ratio, biocompatibility and the potential for high s...
journal_title：Biotechnology advances
pub_type： 杂志文章,评审
doi：10.1016/j.biotechadv.2011.08.005
更新日期：2012-09-01 00:00:00
abstract：:Enzymes are essential and ubiquitous biocatalysts involved in various metabolic pathways and used in many industrial processes. Here, we reframe enzymes not just as biocatalysts transforming bioproducts but also as sensitive probes for exploring the structure and composition of complex bioproducts, like meat tissue, d...
journal_title：Biotechnology advances
pub_type： 杂志文章,评审
doi：10.1016/j.biotechadv.2020.107546
更新日期：2020-01-01 00:00:00
abstract：:Herbal remedies were the first medicines used by humans due to the many pharmacologically active secondary metabolites produced by plants. Some of these metabolites inhibit cell division and can therefore be used for the treatment of cancer, e.g. the mitostatic drug paclitaxel (Taxol). The ability of plants to produce...
journal_title：Biotechnology advances
pub_type： 杂志文章,评审
doi：10.1016/j.biotechadv.2018.02.002
更新日期：2018-01-01 00:00:00
abstract：:The population of sub-Saharan Africa is at risk from multiple, poverty-related endemic diseases. HIV and malaria are the most prevalent, but they disproportionately affect different groups of people, i.e. HIV predominantly affects sexually-active adults whereas malaria has a greater impact on children and pregnant wom...
journal_title：Biotechnology advances
pub_type： 杂志文章,评审
doi：10.1016/j.biotechadv.2014.02.004
更新日期：2014-05-01 00:00:00
abstract：:New developments in magnetic labelling techniques for cells and microspheres have extended the useful range of magnetic separation, particularly high gradient magnetic separation, into biotechnical areas. The basic magnetic principles involved are reviewed and representative samples of labelling techniques and results...
journal_title：Biotechnology advances
pub_type： 杂志文章
doi：10.1016/0734-9750(84)90241-6
更新日期：1984-01-01 00:00:00
abstract：:Next generation sequencing is in the process of evolving from a technology used for research purposes to one which is applied in clinical diagnostics. Recently introduced high throughput and benchtop instruments offer fully automated sequencing runs at a lower cost per base and faster assay times. In turn, the complex...
journal_title：Biotechnology advances
pub_type： 杂志文章,评审
doi：10.1016/j.biotechadv.2020.107537
更新日期：2020-01-01 00:00:00
