Where bio meets nano: the many uses for nanoporous aluminum oxide in biotechnology.

abstract：:Plant cell suspension culture (PCSC) has emerged as a viable technology to produce plant specialized metabolites (PSM). While Taxol® and ginsenoside are two examples of successfully commercialized PCSC-derived PSM, widespread utilization of the PCSC platform has yet to be realized primarily due to a lack of understand...

journal_title：Biotechnology advances

authors： Arya SS,Rookes JE,Cahill DM,Lenka SK

更新日期：2020-12-01 00:00:00

abstract：:Malolactic fermentation (MLF) in wine can be accomplished by relying on the natural microflora or by inducing through inoculation of a specific strain(s) of malolactic bacteria, primarily strains of Leuconostoc oenos. Problems with inducing MLF include intrinsic factors of the grape must such as pH, presence of sulfur...

journal_title：Biotechnology advances

authors： Edwards CG,Beelman RB

更新日期：1989-01-01 00:00:00

abstract：:Lignin is a major component of lignocellulosic biomass and as such, it is processed in enormous amounts in the pulp and paper industry worldwide. In such industry it mainly serves the purpose of a fuel to provide process steam and electricity, and to a minor extent to provide low grade heat for external purposes. Also...

journal_title：Biotechnology advances

authors： Abdelaziz OY,Brink DP,Prothmann J,Ravi K,Sun M,García-Hidalgo J,Sandahl M,Hulteberg CP,Turner C,Lidén G,Gorwa-Grauslund MF

更新日期：2016-12-01 00:00:00

abstract：:Aptamers are short single-stranded nucleic acid sequences capable of binding to target molecules in a way similar to antibodies. Due to various advantages such as prolonged shelf life, low batch to batch variation, low/no immunogenicity, freedom to incorporate chemical modification for enhanced stability and targeting...

journal_title：Biotechnology advances

authors： Wang T,Chen C,Larcher LM,Barrero RA,Veedu RN

更新日期：2019-01-01 00:00:00

abstract：:Mitochondrial DNA (mtDNA) mutations have been involved in disease, aging and cancer and furthermore exploited for evolutionary and forensic investigation. When investigating mtDNA mutations the peculiar aspects of mitochondrial genetics, such as heteroplasmy and threshold effect, require suitable approaches which must...

journal_title：Biotechnology advances

authors： Kurelac I,Lang M,Zuntini R,Calabrese C,Simone D,Vicario S,Santamaria M,Attimonelli M,Romeo G,Gasparre G

更新日期：2012-01-01 00:00:00

abstract：:Cryptosporidium parvum is an obligate protozoan parasite responsible for the diarrheal illness cryptosporidiosis in humans and animals. Although C. parvum is particularly pathogenic in immunocompromised hosts, the molecular mechanisms by which C. parvum invades the host epithelial cells are not well understood. Charac...

journal_title：Biotechnology advances

authors： Boulter-Bitzer JI,Lee H,Trevors JT

更新日期：2007-01-01 00:00:00

abstract：:With the emergence of nanotechnology, researchers become more interested in studying the unique properties of nanoscale materials. Electrospinning, an electrostatic fiber fabrication technique has evinced more interest and attention in recent years due to its versatility and potential for applications in diverse field...

journal_title：Biotechnology advances

authors： Bhardwaj N,Kundu SC

更新日期：2010-05-01 00:00:00

abstract：:The review assesses current status and attempts to forecast trends in the development of lectin biorecognition technology. The progressive trend is characterized scientometrically and reflects the current transient situation, when standard low-throughput lectin-based techniques are being replaced by a novel microarray...

journal_title：Biotechnology advances

authors： Gemeiner P,Mislovicová D,Tkác J,Svitel J,Pätoprstý V,Hrabárová E,Kogan G,Kozár T

更新日期：2009-01-01 00:00:00

abstract：:Surface display systems have been developed to express target molecules on almost all types of biological entities from viruses to mammalian cells and on a variety of synthetic particles. Various approaches have been developed to achieve the display of many different target molecules, aiming at several technological a...

journal_title：Biotechnology advances

authors： Ricca E,Baccigalupi L,Isticato R

更新日期：2020-12-31 00:00:00

abstract：:An increasing number of proteins are currently available on the market as therapeutics and this branch of the pharmaceutical industry will expand substantially during the coming years. As many diseases result from dysfunction of proteins forming multicomponent complexes, protein drugs with their inherent high specific...

journal_title：Biotechnology advances

authors： Szlachcic A,Zakrzewska M,Otlewski J

更新日期：2011-07-01 00:00:00

abstract：:The control of hepatitis B virus (HBV) infection is a challenging task, specifically in developing countries there is limited access to diagnostics and antiviral treatment mainly due to high costs and insufficient healthcare infrastructure. Although the current diagnostic technologies can reliably detect HBV, they are...

journal_title：Biotechnology advances

authors： Yildiz UH,Inci F,Wang S,Toy M,Tekin HC,Javaid A,Lau DT,Demirci U

更新日期：2015-01-01 00:00:00

abstract：:The transition from the vegetative to reproductive stage followed by inflorescence is a critical step in plant life; therefore, studies of the genes that influence flowering time have always been of great interest to scientists. Flowering is a process controlled by many genes interacting mutually in a genetic network,...

journal_title：Biotechnology advances

authors： Milec Z,Valárik M,Bartoš J,Safář J

更新日期：2014-01-01 00:00:00

abstract：:The high plasticity of the active-site cavity of cytochromes P450, permitting reactivity toward a vast array of compounds, makes these enzymes attractive targets for biotechnological application. Escalating attention in this area is driven by remarkable progress in the rational design by DNA shuffling of self-sufficie...

journal_title：Biotechnology advances

authors： Hlavica P

更新日期：2009-03-01 00:00:00

abstract：:Food additives and colorants are extensively used in the food industry to improve food quality and safety during processing, storage and packing. Sourcing of these molecules is predominately through three means: extraction from natural sources, chemical synthesis, and bio-production, with the first two being the most ...

journal_title：Biotechnology advances

authors： Sun L,Xin F,Alper HS

更新日期：2021-01-01 00:00:00

abstract：:The present review provides up-to-date information on the occurrence and methodologies used for producing and purifying endo-β-mannanases and a comprehensive comparison of their biochemical properties. The amalgamation of biochemical, molecular and structural biology approaches which have been used for understanding e...

journal_title：Biotechnology advances

authors： Srivastava PK,Kapoor M

更新日期：2017-01-01 00:00:00

abstract：:Polyamines (PAs) are ubiquitous biogenic amines that have been implicated in diverse cellular functions in widely distributed organisms. In plants, mutant and transgenic plants with altered activity pointed to their involvement with different abiotic and biotic stresses. Furthermore, microarray, transcriptomic and pro...

journal_title：Biotechnology advances

authors： Hussain SS,Ali M,Ahmad M,Siddique KH

更新日期：2011-05-01 00:00:00

abstract：:Due to concerns about the unsustainability and predictable shortage of fossil feedstocks, research efforts are currently being made to develop new processes for production of commodities using alternative feedstocks. 3-Hydroxypropionic acid (CAS 503-66-2) was recognised by the US Department of Energy as one of the mos...

journal_title：Biotechnology advances

authors： de Fouchécour F,Sánchez-Castañeda AK,Saulou-Bérion C,Spinnler HÉ

更新日期：2018-01-01 00:00:00

abstract：:Liquid formulation of therapeutic proteins is a maturing technology. Demand for products that are easy to use in the clinic or that are amenable to self-administration make a ready to use liquid formulation desirable. Most modern liquid formulations have a simple composition; comprising a buffer, a tonicity modifier, ...

journal_title：Biotechnology advances

authors： Falconer RJ

更新日期：2019-11-15 00:00:00

abstract：:The population of sub-Saharan Africa is at risk from multiple, poverty-related endemic diseases. HIV and malaria are the most prevalent, but they disproportionately affect different groups of people, i.e. HIV predominantly affects sexually-active adults whereas malaria has a greater impact on children and pregnant wom...

journal_title：Biotechnology advances

authors： Vamvaka E,Twyman RM,Christou P,Capell T

更新日期：2014-05-01 00:00:00

abstract：:In order to decrease carbon emissions and negative environmental impacts of various pollutants, biofuel/biochemical production should be promoted for replacing fossil-based industrial processes. Utilization of abundant lignocellulosic biomass as a feedstock has recently become an attractive option. In this review, we ...

journal_title：Biotechnology advances

authors： Tanaka T,Kondo A

更新日期：2015-11-15 00:00:00

abstract：:Iron is indispensible for life and essential for such processes as oxygen transport, electron transfer and DNA synthesis. Transferrin (Tf) is a ubiquitous protein with a central role in iron transport and metabolism. There is evidence, however, that Tf has many other biological roles in addition to its primary functio...

journal_title：Biotechnology advances

authors： Brandsma ME,Jevnikar AM,Ma S

更新日期：2011-03-01 00:00:00

abstract：:Ribosomally synthesized peptides with antimicrobial properties (antimicrobial peptides-AMPs) are produced by eukaryotes and prokaryotes and represent crucial components of their defense systems against microorganisms. Although they differ in structure, they are nearly all cationic and very often amphiphilic, which ref...

journal_title：Biotechnology advances

authors： Papagianni M

更新日期：2003-09-01 00:00:00

abstract：:The kinetic resolution of racemates and desymmetrization are the most common approaches to the preparation of enantiomerically enriched compounds. These procedures allow the access of high valuable, chiral building blocks for many purposes in academic or industrial R&D endeavors. Nevertheless, the scope of stereochemi...

journal_title：Biotechnology advances

authors： Cunha RL,Ferreira EA,Oliveira CS,Omori ÁT

更新日期：2015-09-01 00:00:00

abstract：:Gene technology has facilitated the biologization of manufacturing, i.e. the use and production of complex biological molecules and systems at an industrial scale. Monoclonal antibodies (mAbs) are currently the major class of biopharmaceutical products, but they are typically used to treat specific diseases which indi...

journal_title：Biotechnology advances

authors： Buyel JF,Twyman RM,Fischer R

更新日期：2017-07-01 00:00:00

abstract：:Tissue maceration was generally elucidated by the action of endo-polygalacturonase and endo-pectate or -pectin lyase (endo-PAL or -PNL). In a process of screening of Erwinia and Pseudomonas strains for enzymatic pulping of pectocellulosic bast fibers, it was found that their PAL productivity was not completely related...

journal_title：Biotechnology advances

authors： Kobayashi Y,Komae K,Tanabe H,Matsuo R

更新日期：1988-01-01 00:00:00

abstract：:Microalgae are regarded as a potential biomass source for biofuel purposes. With regard to bioethanol production, microalgae seem to overcome traditional substrate drawbacks. Enzymatic activities are responsible for carbon allocation and hence for carbohydrate profiles. Enzyme activities may be manipulated by metaboli...

journal_title：Biotechnology advances

authors： González-Fernández C,Ballesteros M

更新日期：2012-11-01 00:00:00

abstract：:To screen antibody libraries that contain many millions of different clones, a selection system is required with an efficiency comparable to that of the immune system. This can be achieved by displaying antibodies on the surface of microorganisms containing the antibody's gene, analogous to the expression of the IgM a...

journal_title：Biotechnology advances

authors： Little M,Breitling F,Micheel B,Dübel S

更新日期：1994-01-01 00:00:00

abstract：:Bradyrhizobium elkanii produces rhizobitoxine, an enol-ether amino acid, which has been regarded as a phytotoxin because it causes chlorosis in soybeans. However, recent studies have revealed that rhizobitoxine plays a positive role in establishing symbiosis between B. elkanii and host legumes: rhizobitoxine enhances ...

journal_title：Biotechnology advances

authors： Sugawara M,Okazaki S,Nukui N,Ezura H,Mitsui H,Minamisawa K

更新日期：2006-07-01 00:00:00

abstract：:In the wake of the success of aerobic granulation in sequential batch reactors (SBRs) for treating wastewater, attention is beginning to turn to continuous flow applications. This is a necessary step given the advantages of continuous flow treatment processes and the fact that the majority of full-scale wastewater tre...

journal_title：Biotechnology advances

authors： Kent TR,Bott CB,Wang ZW

更新日期：2018-01-01 00:00:00

abstract：:The degradation of plant biomass is a major challenge towards the production of bio-based compounds and materials. As key lignocellulolytic enzyme producers, filamentous fungi represent a promising reservoir to tackle this challenge. Among them, the coprophilous ascomycete Podospora anserina has been used as a model o...

journal_title：Biotechnology advances

authors： Couturier M,Tangthirasunun N,Ning X,Brun S,Gautier V,Bennati-Granier C,Silar P,Berrin JG

更新日期：2016-09-01 00:00:00