Prevention of bubonic and pneumonic plague using plant-derived vaccines.

abstract：:The byproduct of cheese-producing industries, cheese whey, is considered as an environmental pollutant due to its high BOD and COD concentrations. The high organic load of whey arises from the presence of residual milk nutrients. As demand for milk-derived products is increasing, it leads to increased production of wh...

journal_title：Biotechnology advances

authors： Yadav JS,Yan S,Pilli S,Kumar L,Tyagi RD,Surampalli RY

更新日期：2015-11-01 00:00:00

abstract：:In the biological milieu of a cell, soluble crowding molecules and rigid confined environments strongly influence whether the protein is properly folded, intrinsically disordered proteins assemble into distinct phases, or a denatured or aggregated protein species is favored. Such crowding and confinement factors act t...

journal_title：Biotechnology advances

authors： Simpson LW,Good TA,Leach JB

更新日期：2020-01-01 00:00:00

abstract：:Next generation sequencing is in the process of evolving from a technology used for research purposes to one which is applied in clinical diagnostics. Recently introduced high throughput and benchtop instruments offer fully automated sequencing runs at a lower cost per base and faster assay times. In turn, the complex...

journal_title：Biotechnology advances

authors： Hess JF,Kohl TA,Kotrová M,Rönsch K,Paprotka T,Mohr V,Hutzenlaub T,Brüggemann M,Zengerle R,Niemann S,Paust N

更新日期：2020-01-01 00:00:00

abstract：:The potential for gene therapy to cure a wide range of diseases has lead to high expectations and a great increase in research efforts in this area. At present, viral vectors are the most efficient means of delivering a corrective gene into human cells. While a number of different viral vectors are under development, ...

journal_title：Biotechnology advances

authors： McTaggart S,Al-Rubeai M

更新日期：2002-04-01 00:00:00

abstract：:Dinoflagellate microalgae are an important source of marine biotoxins. Bioactives from dinoflagellates are attracting increasing attention because of their impact on the safety of seafood and potential uses in biomedical, toxicological and pharmacological research. Here we review the potential applications of dinoflag...

journal_title：Biotechnology advances

authors： Gallardo-Rodríguez J,Sánchez-Mirón A,García-Camacho F,López-Rosales L,Chisti Y,Molina-Grima E

更新日期：2012-11-01 00:00:00

abstract：:Traditional technologies are required to meet specific, quantitative standards of safety and performance. In tissue engineering, similar standards will have to be developed to enable routine clinical use and customized tissue fabrication. In this essay, we discuss a framework of concepts leading towards general design...

journal_title：Biotechnology advances

authors： Nawroth JC,Parker KK

更新日期：2013-09-01 00:00:00

abstract：:This work reviews applications of high added value molecules produced from microalgae. Older forms of valorization - health food and quality feed, polyunsaturated fatty acids, pigments, carbohydrates - are currently penetrating their markets. They are driven by desirable properties: texturer and dye for food industry,...

journal_title：Biotechnology advances

authors： Levasseur W,Perré P,Pozzobon V

更新日期：2020-01-01 00:00:00

abstract：:β-Galactosidases, an important class of glycosidases, naturally catalyze the hydrolysis of β-galactosidic bonds in oligosaccharides and polysaccharides. Traditionally, these enzymes have been used to degrade lactose in dairy products, which are beneficial for lactose-intolerant people. Attractively, β-galactosidases e...

journal_title：Biotechnology advances

authors： Lu L,Guo L,Wang K,Liu Y,Xiao M

更新日期：2020-01-01 00:00:00

abstract：:The bioactive flavonoids are considered as the most important phytochemicals in food, which exert a wide range of biological benefits for human being. Microbial biotransformation strategies for production of flavonoids have attracted considerable interest because they allow yielding novel flavonoids, which do not exis...

journal_title：Biotechnology advances

authors： Cao H,Chen X,Jassbi AR,Xiao J

更新日期：2015-01-01 00:00:00

abstract：:Agrin and neuregulin are broadly expressed molecules that have significant developmental roles. Here we review the diverse temporal and spatial expression patterns and functions of these molecules and the impact that dysregulation may have on a number of disease states. Many know agrin as a modulator of synaptogenesis...

journal_title：Biotechnology advances

authors： Williams S,Ryan C,Jacobson C

更新日期：2008-05-01 00:00:00

abstract：:The population of sub-Saharan Africa is at risk from multiple, poverty-related endemic diseases. HIV and malaria are the most prevalent, but they disproportionately affect different groups of people, i.e. HIV predominantly affects sexually-active adults whereas malaria has a greater impact on children and pregnant wom...

journal_title：Biotechnology advances

authors： Vamvaka E,Twyman RM,Christou P,Capell T

更新日期：2014-05-01 00:00:00

abstract：:Lactoferrin, the main iron-binding protein of milk, has biological activities that are essential for the newborn and are beneficial for adults. Given this beneficial effect, there is broad interest in exogenous sources of lactoferrin in human nutrition. Consequently, several transgenic approaches to produce lactoferri...

journal_title：Biotechnology advances

authors： Conesa C,Calvo M,Sánchez L

更新日期：2010-11-01 00:00:00

abstract：:A rapidly growing body of experimental evidence has begun to shed light on the wide ranging molecular mechanisms which modulate intra- and inter-cellular communications. A substantial quantity of the available knowledge has only been uncovered in recent years, and we are learning that donor cells release nanovesicles,...

journal_title：Biotechnology advances

authors： Farooqi AA,Desai NN,Qureshi MZ,Librelotto DRN,Gasparri ML,Bishayee A,Nabavi SM,Curti V,Daglia M

更新日期：2018-01-01 00:00:00

abstract：:This paper addresses the circumstances of germplasm contamination and updates on transmission of pathogenic agents by embryos produced in vitro and by associated techniques. It has been shown that some pathogenic agents might have been associated with the follicular oocytes and oviductal cells, collected for in vitro ...

journal_title：Biotechnology advances

authors： Bielanski A

更新日期：1997-01-01 00:00:00

abstract：:The present review provides up-to-date information on the occurrence and methodologies used for producing and purifying endo-β-mannanases and a comprehensive comparison of their biochemical properties. The amalgamation of biochemical, molecular and structural biology approaches which have been used for understanding e...

journal_title：Biotechnology advances

authors： Srivastava PK,Kapoor M

更新日期：2017-01-01 00:00:00

abstract：:Ribosomally synthesized peptides with antimicrobial properties (antimicrobial peptides-AMPs) are produced by eukaryotes and prokaryotes and represent crucial components of their defense systems against microorganisms. Although they differ in structure, they are nearly all cationic and very often amphiphilic, which ref...

journal_title：Biotechnology advances

authors： Papagianni M

更新日期：2003-09-01 00:00:00

abstract：:The concept of the Truncated Light-harvesting chlorophyll Antenna (TLA) size, as a tool by which to maximize sunlight utilization and photosynthetic productivity in microalgal mass cultures or high-density plant canopies, is discussed. TLA technology is known to improve sunlight-to-product energy conversion efficienci...

journal_title：Biotechnology advances

authors： Kirst H,Melis A

更新日期：2014-01-01 00:00:00

abstract：:Polyamines (PAs) are ubiquitous biogenic amines that have been implicated in diverse cellular functions in widely distributed organisms. In plants, mutant and transgenic plants with altered activity pointed to their involvement with different abiotic and biotic stresses. Furthermore, microarray, transcriptomic and pro...

journal_title：Biotechnology advances

authors： Hussain SS,Ali M,Ahmad M,Siddique KH

更新日期：2011-05-01 00:00:00

abstract：:Biomass, a renewable, sustainable and carbon dioxide neutral resource, has received widespread attention in the energy market as an alternative to fossil fuels. Thermal-chemical conversion of biomass to produce biofuels is a promising technology with many commercial applications. This paper reviewed the state-of-the-a...

journal_title：Biotechnology advances

authors： Ma L,Wang T,Liu Q,Zhang X,Ma W,Zhang Q

更新日期：2012-07-01 00:00:00

abstract：:Circulating tumor cells (CTCs) are a major contributor of cancer metastases and hold a promising prognostic significance in cancer detection. Performing functional and molecular characterization of CTCs provides an in-depth knowledge about this lethal disease. Researchers are making efforts to design devices and devel...

journal_title：Biotechnology advances

authors： Sharma S,Zhuang R,Long M,Pavlovic M,Kang Y,Ilyas A,Asghar W

更新日期：2018-01-01 00:00:00

abstract：:This review elaborates on the recent development of microbial sterol biotransformation systems. Particular emphasis is laid on the new enzymatic approach investigating the cleavage of sterol side chain. New developments in the area of immobilized cell system and use of organic media along with recent reviews on side c...

journal_title：Biotechnology advances

authors： Ahmad S,Garg SK,Johri BN

更新日期：1992-01-01 00:00:00

abstract：:Nucleoside derivatives are a class of compounds that have attracted intense interest in biotechnology and medicine. Use of biocatalysts opens exciting opportunities for selective synthesis of many nucleoside derivatives, and such an approach offers simplicity, exquisite selectivity and environmentally benign processes...

journal_title：Biotechnology advances

authors： Li N,Smith TJ,Zong MH

更新日期：2010-05-01 00:00:00

abstract：:Bradyrhizobium elkanii produces rhizobitoxine, an enol-ether amino acid, which has been regarded as a phytotoxin because it causes chlorosis in soybeans. However, recent studies have revealed that rhizobitoxine plays a positive role in establishing symbiosis between B. elkanii and host legumes: rhizobitoxine enhances ...

journal_title：Biotechnology advances

authors： Sugawara M,Okazaki S,Nukui N,Ezura H,Mitsui H,Minamisawa K

更新日期：2006-07-01 00:00:00

abstract：:The biotech industry is, nowadays, facing unparalleled challenges due to the enhanced demand for biotechnology-based human therapeutic products, such as monoclonal antibodies (mAbs). This has led companies to improve substantially their upstream processes, with the yield of monoclonals increasing to titers never seen ...

journal_title：Biotechnology advances

authors： Rosa PA,Azevedo AM,Sommerfeld S,Bäcker W,Aires-Barros MR

更新日期：2011-11-01 00:00:00

abstract：:Sucrose synthase (SuSy, EC 2.4.1.13) is a glycosyltransferase (GT) long known from plants and more recently discovered in bacteria. The enzyme catalyzes the reversible transfer of a glucosyl moiety between fructose and a nucleoside diphosphate (NDP) (sucrose+NDP↔NDP-glucose+fructose). The equilibrium for sucrose conve...

journal_title：Biotechnology advances

authors： Schmölzer K,Gutmann A,Diricks M,Desmet T,Nidetzky B

更新日期：2016-03-01 00:00:00

abstract：:Bacteria produce a large number of different halogenated secondary metabolites. Haloperoxidases are believed to be the enzymes responsible for the halogenation reaction. Two classes of haloperoxidases, heme and nonheme, were isolated from different bacteria and their role in the biosynthesis of halogenated secondary m...

journal_title：Biotechnology advances

authors： Van Pée KH

更新日期：1990-01-01 00:00:00

abstract：:Orchids (Orchidaceae) are one of the most diverse plant groups on the planet with over 25,000 species. For over a century, scientists and horticulturalists have been fascinated by their complex floral morphology, pollinator specificity and multiple ethnobotanical uses, including as food, flavourings, medicines, orname...

journal_title：Biotechnology advances

authors： Popova E,Kim HH,Saxena PK,Engelmann F,Pritchard HW

更新日期：2016-07-01 00:00:00

abstract：:Cell-free protein synthesis systems enable the direct in vitro expression of proteins from template DNA or RNA. Use of biochemical and bioengineering techniques has greatly improved the yields and productivities of cell-free systems. In some cases, the yields approach the in vivo levels. Moreover, in vitro systems are...

journal_title：Biotechnology advances

authors： Nakano H,Yamane T

更新日期：1998-03-01 00:00:00

abstract：:For both nitrogen and carbon metabolism there exist specific regulatory mechanisms to enable cells to assimilate a wide variety of nitrogen and carbon sources. Superimposed are regulatory circuits, the so called nitrogen and carbon catabolite regulation, to allow for selective use of "rich" sources first and "poor" so...

journal_title：Biotechnology advances

authors： Hütter R,Niederberger P

更新日期：1983-01-01 00:00:00

abstract：:Phenotypic profiling of natural, engineered or synthetic cells has increasingly become a bottleneck in the mining and engineering of cell factories. Single-cell phenotyping technologies are highly promising for tackling this hurdle, yet ideally they should allow non-invasive live-cell probing, be label-free, provide l...

journal_title：Biotechnology advances

authors： He Y,Wang X,Ma B,Xu J

更新日期：2019-11-01 00:00:00