Abstract:
:The concept of the Truncated Light-harvesting chlorophyll Antenna (TLA) size, as a tool by which to maximize sunlight utilization and photosynthetic productivity in microalgal mass cultures or high-density plant canopies, is discussed. TLA technology is known to improve sunlight-to-product energy conversion efficiencies and is hereby exemplified by photosynthetic productivity estimates of wild type and a TLA strain under simulated mass culture conditions. Recent advances in the generation of TLA-type mutants by targeting genes of the chloroplast signal-recognition particle (CpSRP) pathway, affecting the thylakoid membrane assembly of light-harvesting proteins, are also summarized. Two distinct CpSRP assembly pathways are recognized, one entailing post-translational, the other a co-translational mechanism. Differences between the post-translational and co-translational integration mechanisms are outlined, as these pertain to the CpSRP-mediated assembly of thylakoid membrane protein complexes in higher plants and green microalgae. The applicability of the CpSRP pathway genes in efforts to generate TLA-type strains with enhanced solar energy conversion efficiency in photosynthesis is evaluated.
journal_name
Biotechnol Advjournal_title
Biotechnology advancesauthors
Kirst H,Melis Adoi
10.1016/j.biotechadv.2013.08.018subject
Has Abstractpub_date
2014-01-01 00:00:00pages
66-72issue
1eissn
0734-9750issn
1873-1899pii
S0734-9750(13)00152-3journal_volume
32pub_type
杂志文章,评审abstract::Microbial electrosynthesis (MES) is a process that uses electricity as an energy source for driving the production of chemicals and fuels using microorganisms and CO2 or organics as carbon sources. The development of this highly interdisciplinary technology on the interface between biotechnology and electrochemistry r...
journal_title:Biotechnology advances
pub_type: 杂志文章,评审
doi:10.1016/j.biotechadv.2015.03.002
更新日期:2015-11-01 00:00:00
abstract::Sucrose synthase (SuSy, EC 2.4.1.13) is a glycosyltransferase (GT) long known from plants and more recently discovered in bacteria. The enzyme catalyzes the reversible transfer of a glucosyl moiety between fructose and a nucleoside diphosphate (NDP) (sucrose+NDP↔NDP-glucose+fructose). The equilibrium for sucrose conve...
journal_title:Biotechnology advances
pub_type: 杂志文章,评审
doi:10.1016/j.biotechadv.2015.11.003
更新日期:2016-03-01 00:00:00
abstract::Vitrification is a new approach to oocyte and embryo cryoconservation. It consists in the solidification of a solution caused not by crystallization, but by a drastic increase in viscosity during cooling. The application of this approach to cryoconservation of oocytes and embryos of different species depends upon the ...
journal_title:Biotechnology advances
pub_type: 杂志文章
doi:10.1016/0734-9750(94)90019-1
更新日期:1994-01-01 00:00:00
abstract::Surface display systems have been developed to express target molecules on almost all types of biological entities from viruses to mammalian cells and on a variety of synthetic particles. Various approaches have been developed to achieve the display of many different target molecules, aiming at several technological a...
journal_title:Biotechnology advances
pub_type: 杂志文章,评审
doi:10.1016/j.biotechadv.2020.107693
更新日期:2020-12-31 00:00:00
abstract::Pichia pastoris, a methylotrophic yeast, is an established system for the production of heterologous proteins, particularly biopharmaceuticals and industrial enzymes. To maximise and optimise the production of recombinant products, recent molecular research has focused on numerous issues including the design of expres...
journal_title:Biotechnology advances
pub_type: 杂志文章,评审
doi:10.1016/j.biotechadv.2015.05.008
更新日期:2015-11-01 00:00:00
abstract::We review the recent development of mobile detection instruments used for medical diagnostics, and consider the relative advantages of approaches that utilize the internal sensing capabilities of commercially available mobile communication devices (such as smartphones and tablet computers) compared to those that utili...
journal_title:Biotechnology advances
pub_type: 杂志文章,评审
doi:10.1016/j.biotechadv.2016.02.010
更新日期:2016-05-01 00:00:00
abstract::The population of sub-Saharan Africa is at risk from multiple, poverty-related endemic diseases. HIV and malaria are the most prevalent, but they disproportionately affect different groups of people, i.e. HIV predominantly affects sexually-active adults whereas malaria has a greater impact on children and pregnant wom...
journal_title:Biotechnology advances
pub_type: 杂志文章,评审
doi:10.1016/j.biotechadv.2014.02.004
更新日期:2014-05-01 00:00:00
abstract::2-Phenylethanol (2-PE) is an important aromatic alcohol with a rose-like fragrance. It has been widely applied in the cosmetic, perfume, and food industries and is mainly produced by chemical synthesis. An alternative method for the production of natural flavors and fragrances is the microbial transformation process, ...
journal_title:Biotechnology advances
pub_type: 杂志文章,评审
doi:10.1016/j.biotechadv.2011.05.001
更新日期:2011-11-01 00:00:00
abstract::The yeast, Saccharomyces cerevisiae is currently used for the production of recombinant DNA-generated proteins derived from a variety of eukaryotic organisms. The applications of a yeast-based technology in the production of proteins for pharmaceutical and industrial purposes is discussed including current methods for...
journal_title:Biotechnology advances
pub_type: 杂志文章
doi:10.1016/0734-9750(89)90357-1
更新日期:1989-01-01 00:00:00
abstract::β-Galactosidases, an important class of glycosidases, naturally catalyze the hydrolysis of β-galactosidic bonds in oligosaccharides and polysaccharides. Traditionally, these enzymes have been used to degrade lactose in dairy products, which are beneficial for lactose-intolerant people. Attractively, β-galactosidases e...
journal_title:Biotechnology advances
pub_type: 杂志文章,评审
doi:10.1016/j.biotechadv.2019.107465
更新日期:2020-01-01 00:00:00
abstract::This review elaborates on the recent development of microbial sterol biotransformation systems. Particular emphasis is laid on the new enzymatic approach investigating the cleavage of sterol side chain. New developments in the area of immobilized cell system and use of organic media along with recent reviews on side c...
journal_title:Biotechnology advances
pub_type: 杂志文章
doi:10.1016/0734-9750(92)91351-e
更新日期:1992-01-01 00:00:00
abstract::One of the major bottlenecks in automation and process control of industrial bioprocesses is the lack of suitable sensing devices to accurately measure the concentrations of biomolecules. The measurement of ions (e.g., H(+), NH(4)(+)) and gases (e.g., O(2), CO(2), NH(3)) using standard ion-selective and gas sensing el...
journal_title:Biotechnology advances
pub_type: 杂志文章
doi:10.1016/0734-9750(85)90292-7
更新日期:1985-01-01 00:00:00
abstract::Monogenic diseases are often severe, life-threatening disorders for which lifelong palliative treatment is the only option. Over the last two decades, a number of strategies have been devised with the aim to treat these diseases with a genetic approach. Gene therapy has been under development for many years, yet suffe...
journal_title:Biotechnology advances
pub_type: 杂志文章
doi:10.1016/j.biotechadv.2010.05.019
更新日期:2010-11-01 00:00:00
abstract::Gene technology has facilitated the biologization of manufacturing, i.e. the use and production of complex biological molecules and systems at an industrial scale. Monoclonal antibodies (mAbs) are currently the major class of biopharmaceutical products, but they are typically used to treat specific diseases which indi...
journal_title:Biotechnology advances
pub_type: 杂志文章,评审
doi:10.1016/j.biotechadv.2017.03.011
更新日期:2017-07-01 00:00:00
abstract::Grassland is of major importance for agricultural production and provides valuable ecosystem services. Its impact is likely to rise in changing socio-economic and climatic environments. High yielding forage grass species are major components of sustainable grassland production. Understanding the genome structure and f...
journal_title:Biotechnology advances
pub_type: 杂志文章,评审
doi:10.1016/j.biotechadv.2013.11.010
更新日期:2014-01-01 00:00:00
abstract::Differentiation of cancer cells entails the reversion of phenotype from malignant to the original. The conversion to cell type characteristic for another tissue is named transdifferentiation. Differentiation/transdifferentiation of malignant cells in high grade tumor mass could serve as a nonaggressive approach that p...
journal_title:Biotechnology advances
pub_type: 杂志文章,评审
doi:10.1016/j.biotechadv.2018.04.001
更新日期:2018-11-01 00:00:00
abstract::Osteochondral defect management and repair remain a significant challenge in orthopedic surgery. Osteochondral defects contain damage to both the articular cartilage as well as the underlying subchondral bone. In order to repair an osteochondral defect the needs of the bone, cartilage and the bone-cartilage interface ...
journal_title:Biotechnology advances
pub_type: 杂志文章,评审
doi:10.1016/j.biotechadv.2012.11.004
更新日期:2013-09-01 00:00:00
abstract::"Molecular farming" in plants with significant advantages in cost and safety is touted as a promising platform for the production of complex pharmaceutical proteins. While whole-plant produced biopharmaceuticals account for a significant portion of the preclinical and clinical pipeline, plant cell suspension culture, ...
journal_title:Biotechnology advances
pub_type: 杂志文章
doi:10.1016/j.biotechadv.2011.01.002
更新日期:2011-05-01 00:00:00
abstract::For both nitrogen and carbon metabolism there exist specific regulatory mechanisms to enable cells to assimilate a wide variety of nitrogen and carbon sources. Superimposed are regulatory circuits, the so called nitrogen and carbon catabolite regulation, to allow for selective use of "rich" sources first and "poor" so...
journal_title:Biotechnology advances
pub_type: 杂志文章
doi:10.1016/0734-9750(83)90587-6
更新日期:1983-01-01 00:00:00
abstract::Due to the over-harvesting and deterioration of wild populations, the ever-growing crustacean market is increasingly reliant on aquaculture, driving the need for better management techniques. Since most cultured crustacean species exhibit sexually dimorphic growth patterns, the culture of monosex populations (either a...
journal_title:Biotechnology advances
pub_type: 杂志文章,评审
doi:10.1016/j.biotechadv.2012.04.008
更新日期:2012-11-01 00:00:00
abstract::Polyamines (PAs) are ubiquitous biogenic amines that have been implicated in diverse cellular functions in widely distributed organisms. In plants, mutant and transgenic plants with altered activity pointed to their involvement with different abiotic and biotic stresses. Furthermore, microarray, transcriptomic and pro...
journal_title:Biotechnology advances
pub_type: 杂志文章,评审
doi:10.1016/j.biotechadv.2011.01.003
更新日期:2011-05-01 00:00:00
abstract::Although the history of the golden spice turmeric (Curcuma longa) goes back thousands of years, it is only within the past century that we learned about the chemistry of its active component, curcumin. More than 6000 articles published within the past two decades have discussed the molecular basis for the antioxidant,...
journal_title:Biotechnology advances
pub_type: 杂志文章,评审
doi:10.1016/j.biotechadv.2014.04.004
更新日期:2014-11-01 00:00:00
abstract::Porous aluminum oxide (PAO) is a ceramic formed by an anodization process of pure aluminum that enables the controllable assembly of exceptionally dense and regular nanopores in a planar membrane. As a consequence, PAO has a high porosity, nanopores with high aspect ratio, biocompatibility and the potential for high s...
journal_title:Biotechnology advances
pub_type: 杂志文章,评审
doi:10.1016/j.biotechadv.2011.08.005
更新日期:2012-09-01 00:00:00
abstract::During a tempe fermentation the concentrations of linoleic, and alpha-linolenic acids (ALA) decreased while the concentration of oleic acid increased. During fatty acid synthesis Rhizopus sp. produced only gamma-linolenic acid (GLA) instead of ALA. The amount of GLA in tempe were influenced by varying external paramet...
journal_title:Biotechnology advances
pub_type: 杂志文章
doi:10.1016/0734-9750(93)90016-g
更新日期:1993-01-01 00:00:00
abstract::Volatile organic compounds (VOCs) emitted to the environment highly probably result in ecological and health risks. Many biotechnologies for waste gases containing hydrophobic VOCs have been developed in recent years. However, these biological processes usually exhibit poor removal performances for hydrophobic VOCs du...
journal_title:Biotechnology advances
pub_type: 杂志文章,评审
doi:10.1016/j.biotechadv.2016.06.007
更新日期:2016-11-01 00:00:00
abstract::Iron is indispensible for life and essential for such processes as oxygen transport, electron transfer and DNA synthesis. Transferrin (Tf) is a ubiquitous protein with a central role in iron transport and metabolism. There is evidence, however, that Tf has many other biological roles in addition to its primary functio...
journal_title:Biotechnology advances
pub_type: 杂志文章,评审
doi:10.1016/j.biotechadv.2010.11.007
更新日期:2011-03-01 00:00:00
abstract::Although almost every U.S. pulp mill has a biological wastewater treatment system, these systems based on bacteria, are largely ineffective in the removal of color. For this reason, we have attempted to utilize Phanerochaete chrysosporium, a fungus known to degrade lignin, as the primary organism in a novel waste trea...
journal_title:Biotechnology advances
pub_type: 杂志文章
doi:10.1016/0734-9750(84)90010-7
更新日期:1984-01-01 00:00:00
abstract::Phytoremediation has emerged as a green, passive, solar energy driven and cost effective approach for environmental cleanup when compared to physico-chemical and even other biological methods. Textile dyes and effluents are condemned as one of the worst polluters of our precious water bodies and soils. They are well k...
journal_title:Biotechnology advances
pub_type: 杂志文章,评审
doi:10.1016/j.biotechadv.2015.09.003
更新日期:2015-12-01 00:00:00
abstract::Loxoscelism (the term used to define accidents by the bite of brown spiders) has been reported worldwide. Clinical manifestations following brown spider bites are frequently associated with skin degeneration, a massive inflammatory response at the injured region, intravascular hemolysis, platelet aggregation causing t...
journal_title:Biotechnology advances
pub_type: 杂志文章,评审
doi:10.1016/j.biotechadv.2007.12.003
更新日期:2008-05-01 00:00:00
abstract::Due to concerns about the unsustainability and predictable shortage of fossil feedstocks, research efforts are currently being made to develop new processes for production of commodities using alternative feedstocks. 3-Hydroxypropionic acid (CAS 503-66-2) was recognised by the US Department of Energy as one of the mos...
journal_title:Biotechnology advances
pub_type: 杂志文章,评审
doi:10.1016/j.biotechadv.2018.03.020
更新日期:2018-01-01 00:00:00