Curcumin, a component of golden spice: from bedside to bench and back.

abstract：:Direct interspecies electron transfer (DIET) via electrically conductive pili (e-pili) and c-type cytochrome between acetogens and methanogens has been proposed as an essential pathway for methane production. Supplements of conductive materials have been extensively found to promote methane production in microbial ana...

journal_title：Biotechnology advances

authors： Yin Q,Wu G

更新日期：2019-12-01 00:00:00

abstract：:Surface display systems have been developed to express target molecules on almost all types of biological entities from viruses to mammalian cells and on a variety of synthetic particles. Various approaches have been developed to achieve the display of many different target molecules, aiming at several technological a...

journal_title：Biotechnology advances

authors： Ricca E,Baccigalupi L,Isticato R

更新日期：2020-12-31 00:00:00

abstract：:It has recently been discovered that a number of synthetic chemicals and naturally occurring compounds released into the environment can influence endocrine activity. These endocrine-disrupting compounds (EDCs) are highly varied in structure, provenance, and mode of action (MOA). Many EDCs are anthropogenic, products ...

journal_title：Biotechnology advances

authors： Francois E,Wang DY,Fulthorpe R,Liss SN,Edwards EA

更新日期：2003-12-01 00:00:00

abstract：:The biotech industry is, nowadays, facing unparalleled challenges due to the enhanced demand for biotechnology-based human therapeutic products, such as monoclonal antibodies (mAbs). This has led companies to improve substantially their upstream processes, with the yield of monoclonals increasing to titers never seen ...

journal_title：Biotechnology advances

authors： Rosa PA,Azevedo AM,Sommerfeld S,Bäcker W,Aires-Barros MR

更新日期：2011-11-01 00:00:00

abstract：:Vaccines represent a special class of drugs, capable of stimulating immune system responses against pathogens and tumors. Vaccine development is a lengthy process that includes expensive laboratory experiments in order to assess safety and effectiveness. As the efficacy of a vaccine was demonstrated by biological/chem...

journal_title：Biotechnology advances

authors： Pappalardo F,Pennisi M,Castiglione F,Motta S

更新日期：2010-01-01 00:00:00

abstract：:Cryptosporidium parvum is an obligate protozoan parasite responsible for the diarrheal illness cryptosporidiosis in humans and animals. Although C. parvum is particularly pathogenic in immunocompromised hosts, the molecular mechanisms by which C. parvum invades the host epithelial cells are not well understood. Charac...

journal_title：Biotechnology advances

authors： Boulter-Bitzer JI,Lee H,Trevors JT

更新日期：2007-01-01 00:00:00

abstract：:The aldopentose D-xylose is one of the most abundant sugars in plant biomass and its efficient microbial utilization is of fundamental importance in the overall bioconversion of lignocellulosic materials into liquid fuels and chemicals. The discovery of pentose-fermenting yeasts in the early 1980's led to world wide i...

journal_title：Biotechnology advances

authors： Webb SR,Lee H

更新日期：1990-01-01 00:00:00

abstract：:With the emergence of nanotechnology, researchers become more interested in studying the unique properties of nanoscale materials. Electrospinning, an electrostatic fiber fabrication technique has evinced more interest and attention in recent years due to its versatility and potential for applications in diverse field...

journal_title：Biotechnology advances

authors： Bhardwaj N,Kundu SC

更新日期：2010-05-01 00:00:00

abstract：:Pichia pastoris, a methylotrophic yeast, is an established system for the production of heterologous proteins, particularly biopharmaceuticals and industrial enzymes. To maximise and optimise the production of recombinant products, recent molecular research has focused on numerous issues including the design of expres...

journal_title：Biotechnology advances

authors： Looser V,Bruhlmann B,Bumbak F,Stenger C,Costa M,Camattari A,Fotiadis D,Kovar K

更新日期：2015-11-01 00:00:00

abstract：:Gene delivery vectors must deliver their cargoes into the cytosol or the nucleus, where DNA or siRNA functions in vivo. Therefore it is crucial for the rational design of the nucleic acid delivery carriers. Compared with viral vectors, non-viral vectors have overcome some fatal defections in gene therapy. Whereas the ...

journal_title：Biotechnology advances

authors： Yang J,Liu H,Zhang X

更新日期：2014-07-01 00:00:00

abstract：:The ubiquitous presence of allergens in the human food supply coupled with increased awareness of food allergies warrants undertaking appropriate preventive measures to protect sensitive consumers from unwanted exposure to offending food allergens. Attempts to reduce or eliminate food allergenicity through food proces...

journal_title：Biotechnology advances

authors： Sathe SK,Teuber SS,Roux KH

更新日期：2005-09-01 00:00:00

abstract：:The paradigm for classic vaccines has been to mimic natural infection, and their success relies mostly on the induction of neutralizing antibodies followed by long-lasting immunity. The outcome of aggressive chronic infections such as HIV and HCV, the reappearance of fastidious diseases such as tuberculosis and the pr...

journal_title：Biotechnology advances

authors： Marshall SH

更新日期：2002-11-01 00:00:00

abstract：:We investigated the solid particle flow characteristics and biomass gasification in a clapboard-type internal circulating fluidized bed reactor. The effect of fluidization velocity on particle circulation rate and pressure distribution in the bed showed that fluidization velocities in the high and low velocity zones w...

journal_title：Biotechnology advances

authors： Zhou ZQ,Ma LL,Yin XL,Wu CZ,Huang LC,Wang C

更新日期：2009-09-01 00:00:00

abstract：:Interest in biobutanol, a sustainable vehicle fuel, is increasing due to rising oil prices and concerns of surrounding climate change and the energy crisis. However, the costs of biobutanol with conventional ABE fermentation by Clostridium are higher than the cost of butanol from today's petrochemical processes. Two m...

journal_title：Biotechnology advances

authors： Huang H,Liu H,Gan YR

更新日期：2010-09-01 00:00:00

abstract：:The assessment of ecological risk in genetically modified (GM) biological systems is critically important for decision-making and public acceptance. Cellular automata (CA) provide a potential modeling and simulation framework for representing relationships and interspecies interactions both temporally and spatially. I...

journal_title：Biotechnology advances

authors： Yang J,Wang ZR,Yang DL,Yang Q,Yan J,He MF

更新日期：2009-11-01 00:00:00

abstract：:Plant oil based industrial oleochemistry leads to a large side stream of crude glycerol, which offers itself as a low price carbon source for microbial chemical production. Compared to sugar, glycerol is more reduced and less microorganisms are able to use it as carbon source. An interesting feature of glycerol conver...

journal_title：Biotechnology advances

authors： Russmayer H,Egermeier M,Kalemasi D,Sauer M

更新日期：2019-11-01 00:00:00

abstract：:NADPH oxidase (NOX) is a key player in the network of reactive oxygen species (ROS) producing enzymes. It catalyzes the production of superoxide (O2(-)), that in turn regulates a wide range of biological functions in a broad range of organisms. Plant Noxes are known as respiratory burst oxidase homologs (Rbohs) and ar...

journal_title：Biotechnology advances

authors： Kaur G,Sharma A,Guruprasad K,Pati PK

更新日期：2014-05-01 00:00:00

abstract：:Protein structures contain highly complex systems of voids, making up specific features such as surface clefts or grooves, pockets, protrusions, cavities, pores or channels, and tunnels. Many of them are essential for the migration of solvents, ions and small molecules through proteins, and their binding to the functi...

journal_title：Biotechnology advances

authors： Brezovsky J,Chovancova E,Gora A,Pavelka A,Biedermannova L,Damborsky J

更新日期：2013-01-01 00:00:00

abstract：:Biomass, a renewable, sustainable and carbon dioxide neutral resource, has received widespread attention in the energy market as an alternative to fossil fuels. Thermal-chemical conversion of biomass to produce biofuels is a promising technology with many commercial applications. This paper reviewed the state-of-the-a...

journal_title：Biotechnology advances

authors： Ma L,Wang T,Liu Q,Zhang X,Ma W,Zhang Q

更新日期：2012-07-01 00:00:00

abstract：:Bovine chymosin, an aspartyl protease extracted from abomasum of suckling calves, is synthesized in vivo as preprochymosin and secreted as prochymosin which is autocatalytically activated to chymosin. Chymosin is bilobular, with Asp 32 and Asp 215 acting as the catalytic residues. Chymosin A and chymosin B have pH opt...

journal_title：Biotechnology advances

authors： Mohanty AK,Mukhopadhyay UK,Grover S,Batish VK

更新日期：1999-09-01 00:00:00

abstract：:Vitrification is a new approach to oocyte and embryo cryoconservation. It consists in the solidification of a solution caused not by crystallization, but by a drastic increase in viscosity during cooling. The application of this approach to cryoconservation of oocytes and embryos of different species depends upon the ...

journal_title：Biotechnology advances

authors： Smorag Z,Gajda B

更新日期：1994-01-01 00:00:00

abstract：:The control of hepatitis B virus (HBV) infection is a challenging task, specifically in developing countries there is limited access to diagnostics and antiviral treatment mainly due to high costs and insufficient healthcare infrastructure. Although the current diagnostic technologies can reliably detect HBV, they are...

journal_title：Biotechnology advances

authors： Yildiz UH,Inci F,Wang S,Toy M,Tekin HC,Javaid A,Lau DT,Demirci U

更新日期：2015-01-01 00:00:00

abstract：:Yeast strains Y1, Y4 and Y7 demonstrated high conversion efficiencies for sugars and high abilities to tolerate or metabolize inhibitors in dilute-acid lignocellulosic hydrolysates. Strains Y1 and Y4 completely consumed the glucose within 24 h in dilute-acid lignocellulosic hydrolysate during in situ detoxification, a...

journal_title：Biotechnology advances

authors： Tian S,Zhou G,Yan F,Yu Y,Yang X

更新日期：2009-09-01 00:00:00

abstract：:Silver was widely used in medicine to treat bacterial infections in the 19th and early 20th century, up until the discovery and development of the first modern antibiotics in the 1940s, which were markedly more effective. Since then, every new antibiotic introduced to the clinic has led to an associated development of...

journal_title：Biotechnology advances

authors： Möhler JS,Sim W,Blaskovich MAT,Cooper MA,Ziora ZM

更新日期：2018-01-01 00:00:00

abstract：:Food additives and colorants are extensively used in the food industry to improve food quality and safety during processing, storage and packing. Sourcing of these molecules is predominately through three means: extraction from natural sources, chemical synthesis, and bio-production, with the first two being the most ...

journal_title：Biotechnology advances

authors： Sun L,Xin F,Alper HS

更新日期：2021-01-01 00:00:00

abstract：:Aptamers are short single-stranded nucleic acid sequences capable of binding to target molecules in a way similar to antibodies. Due to various advantages such as prolonged shelf life, low batch to batch variation, low/no immunogenicity, freedom to incorporate chemical modification for enhanced stability and targeting...

journal_title：Biotechnology advances

authors： Wang T,Chen C,Larcher LM,Barrero RA,Veedu RN

更新日期：2019-01-01 00:00:00

abstract：:Both prokaryotes and eukaryotes have pyramid-shaped hierarchical regulatory networks that control gene transcription, enabling the cell to respond to natural environmental changes. In recent years, manipulation and engineering of transcriptional regulatory proteins and networks have been used to elicit microbial toler...

journal_title：Biotechnology advances

authors： Lin Z,Zhang Y,Wang J

更新日期：2013-11-01 00:00:00

abstract：:In recent years, the use of surface-display vectors for displaying polypeptides on the surface of bacteriophage and bacteria, combined with in vitro selection technologies, has transformed the way in which we generate and manipulate ligands, such as enzymes, antibodies and peptides. Phage display is based on expressin...

journal_title：Biotechnology advances

authors： Benhar I

更新日期：2001-02-01 00:00:00

abstract：:Additive manufacturing or 3D printing has spearheaded a revolution in the biomedical sector allowing the rapid prototyping of medical devices. The recent advancements in bioprinting technology are enabling the development of potential new therapeutic options with respect to tissue engineering and regenerative medicine...

journal_title：Biotechnology advances

authors： McCarthy RR,Ullah MW,Booth P,Pei E,Yang G

更新日期：2019-12-01 00:00:00

abstract：:Sucrose synthase (SuSy, EC 2.4.1.13) is a glycosyltransferase (GT) long known from plants and more recently discovered in bacteria. The enzyme catalyzes the reversible transfer of a glucosyl moiety between fructose and a nucleoside diphosphate (NDP) (sucrose+NDP↔NDP-glucose+fructose). The equilibrium for sucrose conve...

journal_title：Biotechnology advances

authors： Schmölzer K,Gutmann A,Diricks M,Desmet T,Nidetzky B

更新日期：2016-03-01 00:00:00