A review of thermal-chemical conversion of lignocellulosic biomass in China.

abstract：:The byproduct of cheese-producing industries, cheese whey, is considered as an environmental pollutant due to its high BOD and COD concentrations. The high organic load of whey arises from the presence of residual milk nutrients. As demand for milk-derived products is increasing, it leads to increased production of wh...

journal_title：Biotechnology advances

authors： Yadav JS,Yan S,Pilli S,Kumar L,Tyagi RD,Surampalli RY

更新日期：2015-11-01 00:00:00

abstract：:Malolactic fermentation (MLF) in wine can be accomplished by relying on the natural microflora or by inducing through inoculation of a specific strain(s) of malolactic bacteria, primarily strains of Leuconostoc oenos. Problems with inducing MLF include intrinsic factors of the grape must such as pH, presence of sulfur...

journal_title：Biotechnology advances

authors： Edwards CG,Beelman RB

更新日期：1989-01-01 00:00:00

abstract：:Within five years, the CRISPR-Cas system has emerged as the dominating tool for genome engineering, while also changing the speed and efficiency of metabolic engineering in conventional (Saccharomyces cerevisiae and Schizosaccharomyces pombe) and non-conventional (Yarrowia lipolytica, Pichia pastoris syn. Komagataella...

journal_title：Biotechnology advances

authors： Raschmanová H,Weninger A,Glieder A,Kovar K,Vogl T

更新日期：2018-01-01 00:00:00

abstract：:Medicinal plants have historically proven their value as a source of molecules with therapeutic potential, and nowadays still represent an important pool for the identification of novel drug leads. In the past decades, pharmaceutical industry focused mainly on libraries of synthetic compounds as drug discovery source....

journal_title：Biotechnology advances

authors： Atanasov AG,Waltenberger B,Pferschy-Wenzig EM,Linder T,Wawrosch C,Uhrin P,Temml V,Wang L,Schwaiger S,Heiss EH,Rollinger JM,Schuster D,Breuss JM,Bochkov V,Mihovilovic MD,Kopp B,Bauer R,Dirsch VM,Stuppner H

更新日期：2015-12-01 00:00:00

abstract：:The aldopentose D-xylose is one of the most abundant sugars in plant biomass and its efficient microbial utilization is of fundamental importance in the overall bioconversion of lignocellulosic materials into liquid fuels and chemicals. The discovery of pentose-fermenting yeasts in the early 1980's led to world wide i...

journal_title：Biotechnology advances

authors： Webb SR,Lee H

更新日期：1990-01-01 00:00:00

abstract：:Bovine chymosin, an aspartyl protease extracted from abomasum of suckling calves, is synthesized in vivo as preprochymosin and secreted as prochymosin which is autocatalytically activated to chymosin. Chymosin is bilobular, with Asp 32 and Asp 215 acting as the catalytic residues. Chymosin A and chymosin B have pH opt...

journal_title：Biotechnology advances

authors： Mohanty AK,Mukhopadhyay UK,Grover S,Batish VK

更新日期：1999-09-01 00:00:00

abstract：:Medicinal plants are essential for improving human health, and around 75% of the population in developing countries relies mainly on herb-based medicines for health care. As the king of herb plants, ginseng has been used for nearly 5,000 years in the oriental and recently in western medicines. Among the compounds stud...

journal_title：Biotechnology advances

authors： Kim YJ,Zhang D,Yang DC

更新日期：2015-11-01 00:00:00

abstract：:The increasing awareness of the energy-environment nexus is compelling the development of technologies that reduce environmental impacts during energy production as well as energy consumption during environmental remediation. Countries spend billions in pollution cleanup projects, and new technologies with low energy ...

journal_title：Biotechnology advances

authors： Wang H,Luo H,Fallgren PH,Jin S,Ren ZJ

更新日期：2015-05-01 00:00:00

abstract：:One of the major bottlenecks in automation and process control of industrial bioprocesses is the lack of suitable sensing devices to accurately measure the concentrations of biomolecules. The measurement of ions (e.g., H(+), NH(4)(+)) and gases (e.g., O(2), CO(2), NH(3)) using standard ion-selective and gas sensing el...

journal_title：Biotechnology advances

authors： Graham A,Moo-Young M

更新日期：1985-01-01 00:00:00

abstract：:Although rational method and global technique have been successfully applied in strain improvement respectively, the demand for engineering complex phenotypes required combinatorial approach. The technology of genome shuffling has been presented as a novel whole genome engineering approach for the rapid improvement of...

journal_title：Biotechnology advances

authors： Gong J,Zheng H,Wu Z,Chen T,Zhao X

更新日期：2009-11-01 00:00:00

abstract：:Gene technology has facilitated the biologization of manufacturing, i.e. the use and production of complex biological molecules and systems at an industrial scale. Monoclonal antibodies (mAbs) are currently the major class of biopharmaceutical products, but they are typically used to treat specific diseases which indi...

journal_title：Biotechnology advances

authors： Buyel JF,Twyman RM,Fischer R

更新日期：2017-07-01 00:00:00

abstract：:Liquid formulation of therapeutic proteins is a maturing technology. Demand for products that are easy to use in the clinic or that are amenable to self-administration make a ready to use liquid formulation desirable. Most modern liquid formulations have a simple composition; comprising a buffer, a tonicity modifier, ...

journal_title：Biotechnology advances

authors： Falconer RJ

更新日期：2019-11-15 00:00:00

abstract：:The diversity of natural compounds is essential for their mechanism of action. The source, structures and structure activity relationship of natural compounds contributed to the development of new classes of chemotherapy agents for over 40 years. The availability of combinatorial chemistry and high-throughput screenin...

journal_title：Biotechnology advances

authors： Mazumder A,Cerella C,Diederich M

更新日期：2018-11-01 00:00:00

abstract：:Agrin and neuregulin are broadly expressed molecules that have significant developmental roles. Here we review the diverse temporal and spatial expression patterns and functions of these molecules and the impact that dysregulation may have on a number of disease states. Many know agrin as a modulator of synaptogenesis...

journal_title：Biotechnology advances

authors： Williams S,Ryan C,Jacobson C

更新日期：2008-05-01 00:00:00

abstract：:Genetically engineered stem cells aid in dissecting basic cell function and are valuable tools for drug discovery, in vivo cell tracking, and gene therapy. Gene transfer into pluripotent stem cells has been a challenge due to their intrinsic feature of growing in clusters and hence not amenable to common gene delivery...

journal_title：Biotechnology advances

authors： Fontes A,Lakshmipathy U

更新日期：2013-11-15 00:00:00

abstract：:The high plasticity of the active-site cavity of cytochromes P450, permitting reactivity toward a vast array of compounds, makes these enzymes attractive targets for biotechnological application. Escalating attention in this area is driven by remarkable progress in the rational design by DNA shuffling of self-sufficie...

journal_title：Biotechnology advances

authors： Hlavica P

更新日期：2009-03-01 00:00:00

abstract：:Cell-free protein synthesis systems enable the direct in vitro expression of proteins from template DNA or RNA. Use of biochemical and bioengineering techniques has greatly improved the yields and productivities of cell-free systems. In some cases, the yields approach the in vivo levels. Moreover, in vitro systems are...

journal_title：Biotechnology advances

authors： Nakano H,Yamane T

更新日期：1998-03-01 00:00:00

abstract：:Selenium is an essential trace element needed for all living organisms. Despite its essentiality, selenium is a potential toxic element to natural ecosystems due to its bioaccumulation potential. Though selenium is found naturally in the earth's crust, especially in carbonate rocks and volcanic and sedimentary soils, ...

journal_title：Biotechnology advances

authors： Tan LC,Nancharaiah YV,van Hullebusch ED,Lens PNL

更新日期：2016-09-01 00:00:00

abstract：:Microalgae are regarded as a potential biomass source for biofuel purposes. With regard to bioethanol production, microalgae seem to overcome traditional substrate drawbacks. Enzymatic activities are responsible for carbon allocation and hence for carbohydrate profiles. Enzyme activities may be manipulated by metaboli...

journal_title：Biotechnology advances

authors： González-Fernández C,Ballesteros M

更新日期：2012-11-01 00:00:00

abstract：:The ability to use progenitor cells for regenerative medicine remains an evolving but elusive clinical goal. A serious obstacle towards widespread use of stem cells for tissue regeneration is the challenges that face these cells when they are placed in vivo into a wound for therapy. These environments are hypoxic, aci...

journal_title：Biotechnology advances

authors： Hyun JS,Tran MC,Wong VW,Chung MT,Lo DD,Montoro DT,Wan DC,Longaker MT

更新日期：2013-09-01 00:00:00

abstract：:Both prokaryotes and eukaryotes have pyramid-shaped hierarchical regulatory networks that control gene transcription, enabling the cell to respond to natural environmental changes. In recent years, manipulation and engineering of transcriptional regulatory proteins and networks have been used to elicit microbial toler...

journal_title：Biotechnology advances

authors： Lin Z,Zhang Y,Wang J

更新日期：2013-11-01 00:00:00

abstract：:In addition to the nuclear genome, organisms have organelle genomes. Most of the DNA present in eukaryotic organisms is located in the cell nucleus. Chloroplasts have independent genomes which are inherited from the mother. Duplicated genes are common in the genomes of all organisms. It is believed that gene duplicati...

journal_title：Biotechnology advances

authors： Xiong AS,Peng RH,Zhuang J,Gao F,Zhu B,Fu XY,Xue Y,Jin XF,Tian YS,Zhao W,Yao QH

更新日期：2009-07-01 00:00:00

abstract：:The biotech industry is, nowadays, facing unparalleled challenges due to the enhanced demand for biotechnology-based human therapeutic products, such as monoclonal antibodies (mAbs). This has led companies to improve substantially their upstream processes, with the yield of monoclonals increasing to titers never seen ...

journal_title：Biotechnology advances

authors： Rosa PA,Azevedo AM,Sommerfeld S,Bäcker W,Aires-Barros MR

更新日期：2011-11-01 00:00:00

abstract：:Due to the over-harvesting and deterioration of wild populations, the ever-growing crustacean market is increasingly reliant on aquaculture, driving the need for better management techniques. Since most cultured crustacean species exhibit sexually dimorphic growth patterns, the culture of monosex populations (either a...

journal_title：Biotechnology advances

authors： Ventura T,Sagi A

更新日期：2012-11-01 00:00:00

abstract：:Actinomycetes are one of the most valuable sources of natural products with industrial and medicinal importance. After more than half a century of exploitation, it has become increasingly challenging to find novel natural products with useful properties as the same known compounds are often repeatedly re-discovered wh...

journal_title：Biotechnology advances

authors： Palazzotto E,Tong Y,Lee SY,Weber T

更新日期：2019-11-01 00:00:00

abstract：:The phenomenon of metal biosorption by microorganisms has been thoroughly documented. Although this phenomenon is exhibited by both living and non-living forms of biomass, the purpose of this chapter will be to review biosorption by the latter. In addition, the application of various technological processes required f...

journal_title：Biotechnology advances

authors： McHale AP,McHale S

更新日期：1994-01-01 00:00:00

abstract：:The use of somatic embryos as artificial seeds for large scale clonal propagation of plants is close to becoming a reality. The quality of the artificial seed depends on the temporal, quantitative and qualitative supply of growth regulator and nutrients along with an optimal physical environment. Desiccation of somati...

journal_title：Biotechnology advances

authors： Senaratna T

更新日期：1992-01-01 00:00:00

abstract：:Traditional technologies are required to meet specific, quantitative standards of safety and performance. In tissue engineering, similar standards will have to be developed to enable routine clinical use and customized tissue fabrication. In this essay, we discuss a framework of concepts leading towards general design...

journal_title：Biotechnology advances

authors： Nawroth JC,Parker KK

更新日期：2013-09-01 00:00:00

abstract：:The assessment of ecological risk in genetically modified (GM) biological systems is critically important for decision-making and public acceptance. Cellular automata (CA) provide a potential modeling and simulation framework for representing relationships and interspecies interactions both temporally and spatially. I...

journal_title：Biotechnology advances

authors： Yang J,Wang ZR,Yang DL,Yang Q,Yan J,He MF

更新日期：2009-11-01 00:00:00

abstract：:An increasing number of proteins are currently available on the market as therapeutics and this branch of the pharmaceutical industry will expand substantially during the coming years. As many diseases result from dysfunction of proteins forming multicomponent complexes, protein drugs with their inherent high specific...

journal_title：Biotechnology advances

authors： Szlachcic A,Zakrzewska M,Otlewski J

更新日期：2011-07-01 00:00:00