Abstract：
:Additive manufacturing or 3D printing has spearheaded a revolution in the biomedical sector allowing the rapid prototyping of medical devices. The recent advancements in bioprinting technology are enabling the development of potential new therapeutic options with respect to tissue engineering and regenerative medicines. Bacterial polysaccharides have been shown to be a central component of the inks used in a variety of bioprinting processes influencing their key features such as the mechanical and thermal properties, printability, biocompatibility, and biodegradability. However, the implantation of any foreign structure in the body comes with an increased risk of bacterial infection and immunogenicity. In recent years, this risk is being potentiated by the rise in nosocomial multidrug-resistant bacterial infections. Inks used in bioprinting are being augmented with antimicrobials to mitigate this risk. The applications of bacterial polysaccharide-based bioinks have the potential to act as a key battlefront in the war against antibiotic resistance. This paper reviews the range of bacterial polysaccharides used in bioprinting and discusses the potential of various bioactive polysaccharides to be integrated into these inks.
journal_name
Biotechnol Advjournal_title
Biotechnology advancesauthors
McCarthy RR,Ullah MW,Booth P,Pei E,Yang Gdoi
10.1016/j.biotechadv.2019.107448subject
Has Abstractpub_date
2019-12-01 00:00:00pages
107448issue
8eissn
0734-9750issn
1873-1899pii
S0734-9750(19)30148-Xjournal_volume
37pub_type
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