Abstract：
:Silver was widely used in medicine to treat bacterial infections in the 19th and early 20th century, up until the discovery and development of the first modern antibiotics in the 1940s, which were markedly more effective. Since then, every new antibiotic introduced to the clinic has led to an associated development of drug resistance. Today, the threat of extensive bacterial resistance to antibiotics has reignited interest in alternative strategies to treat infectious diseases, with silver regaining well-deserved renewed attention. Silver ions are highly disruptive to bacterial integrity and biochemical function, with comparatively minimal toxicity to mammalian cells. This review focuses on the antimicrobial properties of silver and their use in synergistic combination therapy with traditional antibiotic drugs.
journal_name
Biotechnol Advjournal_title
Biotechnology advancesauthors
Möhler JS,Sim W,Blaskovich MAT,Cooper MA,Ziora ZMdoi
10.1016/j.biotechadv.2018.05.004subject
Has Abstractpub_date
2018-01-01 00:00:00pages
1391-1411issue
5eissn
0734-9750issn
1873-1899pii
S0734-9750(18)30094-6journal_volume
36pub_type
杂志文章,评审abstract：:Bradyrhizobium elkanii produces rhizobitoxine, an enol-ether amino acid, which has been regarded as a phytotoxin because it causes chlorosis in soybeans. However, recent studies have revealed that rhizobitoxine plays a positive role in establishing symbiosis between B. elkanii and host legumes: rhizobitoxine enhances ...
journal_title：Biotechnology advances
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journal_title：Biotechnology advances
pub_type： 杂志文章,评审
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journal_title：Biotechnology advances
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journal_title：Biotechnology advances
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journal_title：Biotechnology advances
pub_type： 杂志文章,评审
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更新日期：2020-01-01 00:00:00
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pub_type： 杂志文章
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更新日期：2009-09-01 00:00:00
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journal_title：Biotechnology advances
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更新日期：2018-01-01 00:00:00
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journal_title：Biotechnology advances
pub_type： 杂志文章,评审
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更新日期：2019-01-01 00:00:00
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journal_title：Biotechnology advances
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journal_title：Biotechnology advances
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journal_title：Biotechnology advances
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journal_title：Biotechnology advances
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更新日期：2015-12-01 00:00:00
