Ecological risk assessment of genetically modified crops based on cellular automata modeling.

abstract：:The risk of acquisition of resistance to chemotherapy remains a major hurdle in the management of various types of cancer patients. Several cellular and noncellular mechanisms are involved in developing both intrinsic and acquired resistance in cancer cells toward chemotherapy. This review covers the various multidrug...

journal_title：Biotechnology advances

authors： Saraswathy M,Gong S

更新日期：2013-12-01 00:00:00

abstract：:This work reviews applications of high added value molecules produced from microalgae. Older forms of valorization - health food and quality feed, polyunsaturated fatty acids, pigments, carbohydrates - are currently penetrating their markets. They are driven by desirable properties: texturer and dye for food industry,...

journal_title：Biotechnology advances

authors： Levasseur W,Perré P,Pozzobon V

更新日期：2020-01-01 00:00:00

abstract：:Fatty acid drug discovery (FADD) is defined as the identification of novel, specialized bioactive mediators that are derived from fatty acids and have precise pharmacological/therapeutic potential. A number of reports indicate that dietary intake of omega-3 fatty acids and limited intake of omega-6 promotes overall he...

journal_title：Biotechnology advances

authors： Halade GV,Black LM,Verma MK

更新日期：2018-01-01 00:00:00

abstract：:Ribosomally synthesized peptides with antimicrobial properties (antimicrobial peptides-AMPs) are produced by eukaryotes and prokaryotes and represent crucial components of their defense systems against microorganisms. Although they differ in structure, they are nearly all cationic and very often amphiphilic, which ref...

journal_title：Biotechnology advances

authors： Papagianni M

更新日期：2003-09-01 00:00:00

abstract：:Additive manufacturing or 3D printing has spearheaded a revolution in the biomedical sector allowing the rapid prototyping of medical devices. The recent advancements in bioprinting technology are enabling the development of potential new therapeutic options with respect to tissue engineering and regenerative medicine...

journal_title：Biotechnology advances

authors： McCarthy RR,Ullah MW,Booth P,Pei E,Yang G

更新日期：2019-12-01 00:00:00

abstract：:Cell-free protein synthesis systems enable the direct in vitro expression of proteins from template DNA or RNA. Use of biochemical and bioengineering techniques has greatly improved the yields and productivities of cell-free systems. In some cases, the yields approach the in vivo levels. Moreover, in vitro systems are...

journal_title：Biotechnology advances

authors： Nakano H,Yamane T

更新日期：1998-03-01 00:00:00

abstract：:This review elaborates on the recent development of microbial sterol biotransformation systems. Particular emphasis is laid on the new enzymatic approach investigating the cleavage of sterol side chain. New developments in the area of immobilized cell system and use of organic media along with recent reviews on side c...

journal_title：Biotechnology advances

authors： Ahmad S,Garg SK,Johri BN

更新日期：1992-01-01 00:00:00

abstract：:Biomass, a renewable, sustainable and carbon dioxide neutral resource, has received widespread attention in the energy market as an alternative to fossil fuels. Thermal-chemical conversion of biomass to produce biofuels is a promising technology with many commercial applications. This paper reviewed the state-of-the-a...

journal_title：Biotechnology advances

authors： Ma L,Wang T,Liu Q,Zhang X,Ma W,Zhang Q

更新日期：2012-07-01 00:00:00

abstract：:Culturing of microalgae as an alternative feedstock for biofuel production has received a lot of attention in recent years due to their fast growth rate and ability to accumulate high quantity of lipid and carbohydrate inside their cells for biodiesel and bioethanol production, respectively. In addition, this superior...

journal_title：Biotechnology advances

authors： Lam MK,Lee KT

更新日期：2012-05-01 00:00:00

abstract：:Biotechnological processes based on immobilized viable cells have developed rapidly over the last 30 years. For a long time, basic studies of the physiological behaviour of immobilized cells (IC) have remained in the shadow of the applications. Natural IC structures, i.e. biofilms, are being increasingly investigated ...

journal_title：Biotechnology advances

authors： Junter GA,Jouenne T

更新日期：2004-11-01 00:00:00

abstract：:The marine ecosystem is still an untapped reservoir of biologically active compounds, which have considerable potential to supply food ingredients towards development of new functional foods. With the goal of increasing the availability and chemical diversity of functional marine ingredients, much research has been de...

journal_title：Biotechnology advances

authors： Freitas AC,Rodrigues D,Rocha-Santos TA,Gomes AM,Duarte AC

更新日期：2012-11-01 00:00:00

abstract：:The ability to use progenitor cells for regenerative medicine remains an evolving but elusive clinical goal. A serious obstacle towards widespread use of stem cells for tissue regeneration is the challenges that face these cells when they are placed in vivo into a wound for therapy. These environments are hypoxic, aci...

journal_title：Biotechnology advances

authors： Hyun JS,Tran MC,Wong VW,Chung MT,Lo DD,Montoro DT,Wan DC,Longaker MT

更新日期：2013-09-01 00:00:00

abstract：:One of the major bottlenecks in automation and process control of industrial bioprocesses is the lack of suitable sensing devices to accurately measure the concentrations of biomolecules. The measurement of ions (e.g., H(+), NH(4)(+)) and gases (e.g., O(2), CO(2), NH(3)) using standard ion-selective and gas sensing el...

journal_title：Biotechnology advances

authors： Graham A,Moo-Young M

更新日期：1985-01-01 00:00:00

abstract：:The concept of the Truncated Light-harvesting chlorophyll Antenna (TLA) size, as a tool by which to maximize sunlight utilization and photosynthetic productivity in microalgal mass cultures or high-density plant canopies, is discussed. TLA technology is known to improve sunlight-to-product energy conversion efficienci...

journal_title：Biotechnology advances

authors： Kirst H,Melis A

更新日期：2014-01-01 00:00:00

abstract：:Enzymes are essential and ubiquitous biocatalysts involved in various metabolic pathways and used in many industrial processes. Here, we reframe enzymes not just as biocatalysts transforming bioproducts but also as sensitive probes for exploring the structure and composition of complex bioproducts, like meat tissue, d...

journal_title：Biotechnology advances

authors： Bourlieu C,Astruc T,Barbe S,Berrin JG,Bonnin E,Boutrou R,Hugouvieux V,Le Feunteun S,Paës G

更新日期：2020-01-01 00:00:00

abstract：:Grassland is of major importance for agricultural production and provides valuable ecosystem services. Its impact is likely to rise in changing socio-economic and climatic environments. High yielding forage grass species are major components of sustainable grassland production. Understanding the genome structure and f...

journal_title：Biotechnology advances

authors： Kopecký D,Studer B

更新日期：2014-01-01 00:00:00

abstract：:Many advantages have been claimed over the years for the use of immobilised cells, both as enzyme systems and as whole viable cell systems for complete fermentation reactions. However, few of the claims have been fully substantiated, and may not even be entirely justified. Most research is involved with single applica...

journal_title：Biotechnology advances

authors： Dervakos GA,Webb C

更新日期：1991-01-01 00:00:00

abstract：:Collagens are a family of at least 30 protein types organized as networks. They constitute the main support material of cells under the form of extracellular matrix as well as for membranes in vessels, organs, and tissue compartments. Collagen network abnormalities are at the origin of many diseases, including myopath...

journal_title：Biotechnology advances

authors： Noreen R,Moenner M,Hwu Y,Petibois C

更新日期：2012-11-01 00:00:00

abstract：:Enzyme immobilization is a well-known technique that allows the reuse of the biocatalyst and generally improves its stability. These improved characteristics are of fundamental importance to turn industrial biocatalysis into viable and competitive processes. The immobilization of enzymes can occur through several phys...

journal_title：Biotechnology advances

authors： Mulinari J,Oliveira JV,Hotza D

更新日期：2020-01-01 00:00:00

abstract：:DNA vaccination has been widely explored to develop new, alternative and efficient vaccines for cancer immunotherapy. DNA vaccines offer several benefits such as specific targeting, use of multiple genes to enhance immunity and reduced risk compared to conventional vaccines. Rapid developments in molecular biology and...

journal_title：Biotechnology advances

authors： Iurescia S,Fioretti D,Fazio VM,Rinaldi M

更新日期：2012-01-01 00:00:00

abstract：:Human immunodeficiency virus (HIV) remains a worldwide health problem despite huge investments and research breakthroughs, and no single drug is effective in killing the virus yet. Among new strategies to control HIV infection, the phage display (PD) technology has become a promising tool in the discovery of peptides ...

journal_title：Biotechnology advances

authors： Lopes RS,Queiroz MAF,Gomes STM,Vallinoto ACR,Goulart LR,Ishak R

更新日期：2018-11-15 00:00:00

abstract：:NADPH oxidase (NOX) is a key player in the network of reactive oxygen species (ROS) producing enzymes. It catalyzes the production of superoxide (O2(-)), that in turn regulates a wide range of biological functions in a broad range of organisms. Plant Noxes are known as respiratory burst oxidase homologs (Rbohs) and ar...

journal_title：Biotechnology advances

authors： Kaur G,Sharma A,Guruprasad K,Pati PK

更新日期：2014-05-01 00:00:00

abstract：:Gene delivery vectors must deliver their cargoes into the cytosol or the nucleus, where DNA or siRNA functions in vivo. Therefore it is crucial for the rational design of the nucleic acid delivery carriers. Compared with viral vectors, non-viral vectors have overcome some fatal defections in gene therapy. Whereas the ...

journal_title：Biotechnology advances

authors： Yang J,Liu H,Zhang X

更新日期：2014-07-01 00:00:00

abstract：:Product inhibition of cellulolytic enzymes affects the efficiency of the biocatalytic conversion of lignocellulosic biomass to ethanol and other valuable products. New strategies that focus on reactor designs encompassing product removal, notably glucose removal, during enzymatic cellulose conversion are required for ...

journal_title：Biotechnology advances

authors： Andrić P,Meyer AS,Jensen PA,Dam-Johansen K

更新日期：2010-05-01 00:00:00

abstract：:Considerable progresses have taken place both in the methodology available to study changes in intracellular cytosolic calcium and in our understanding of calcium signaling cascades. It is generally accepted that the global calcium signal system functions importantly in coping with plant abiotic stresses, especially d...

journal_title：Biotechnology advances

authors： Hong-Bo S,Li-Ye C,Ming-An S,Shi-Qing L,Ji-Cheng Y

更新日期：2008-11-01 00:00:00

abstract：:Dihydroxyacetone is extensively used in cosmetic industry as an artificial suntan besides having clinical and biological applications. Thus, it is important to meet the commercial demand of dihydroxyacetone at an economical and qualitative level. Microbial route of production is found to be more favorable for dihydrox...

journal_title：Biotechnology advances

authors： Mishra R,Jain SR,Kumar A

更新日期：2008-07-01 00:00:00

abstract：:The population of sub-Saharan Africa is at risk from multiple, poverty-related endemic diseases. HIV and malaria are the most prevalent, but they disproportionately affect different groups of people, i.e. HIV predominantly affects sexually-active adults whereas malaria has a greater impact on children and pregnant wom...

journal_title：Biotechnology advances

authors： Vamvaka E,Twyman RM,Christou P,Capell T

更新日期：2014-05-01 00:00:00

abstract：:Gene technology has facilitated the biologization of manufacturing, i.e. the use and production of complex biological molecules and systems at an industrial scale. Monoclonal antibodies (mAbs) are currently the major class of biopharmaceutical products, but they are typically used to treat specific diseases which indi...

journal_title：Biotechnology advances

authors： Buyel JF,Twyman RM,Fischer R

更新日期：2017-07-01 00:00:00

abstract：:Worldwide, colorectal cancer (CRC) remains a major cancer type and leading cause of death. Unfortunately, current medical treatments are not sufficient due to lack of effective therapy, adverse side effects, chemoresistance and disease recurrence. In recent decades, epidemiologic observations have highlighted the asso...

journal_title：Biotechnology advances

authors： Afrin S,Giampieri F,Gasparrini M,Forbes-Hernández TY,Cianciosi D,Reboredo-Rodriguez P,Zhang J,Manna PP,Daglia M,Atanasov AG,Battino M

更新日期：2020-01-01 00:00:00

abstract：:Medicinal plants are essential for improving human health, and around 75% of the population in developing countries relies mainly on herb-based medicines for health care. As the king of herb plants, ginseng has been used for nearly 5,000 years in the oriental and recently in western medicines. Among the compounds stud...

journal_title：Biotechnology advances

authors： Kim YJ,Zhang D,Yang DC

更新日期：2015-11-01 00:00:00