Microalgae biofuels: A critical review of issues, problems and the way forward.

Abstract:

:Culturing of microalgae as an alternative feedstock for biofuel production has received a lot of attention in recent years due to their fast growth rate and ability to accumulate high quantity of lipid and carbohydrate inside their cells for biodiesel and bioethanol production, respectively. In addition, this superior feedstock offers several environmental benefits, such as effective land utilization, CO(2) sequestration, self-purification if coupled with wastewater treatment and does not trigger food versus fuel feud. Despite having all these 'theoretical' advantages, review on problems and issues related to energy balance in microalgae biofuel are not clearly addressed until now. Base on the maturity of current technology, the true potential of microalgae biofuel towards energy security and its feasibility for commercialization are still questionable. Thus, this review is aimed to depict the practical problems that are facing the microalgae biofuel industry, covering upstream to downstream activities by accessing the latest research reports and critical data analysis. Apart from that, several interlink solutions to the problems will be suggested with the purpose to bring current microalgae biofuel research into a new dimension and consequently, to revolutionize the entire microalgae biofuel industry towards long-term sustainability.

journal_name

Biotechnol Adv

journal_title

Biotechnology advances

authors

Lam MK,Lee KT

doi

10.1016/j.biotechadv.2011.11.008

subject

Has Abstract

pub_date

2012-05-01 00:00:00

pages

673-90

issue

3

eissn

0734-9750

issn

1873-1899

pii

S0734-9750(11)00200-X

journal_volume

30

pub_type

杂志文章,评审
  • Formation of disulfide bonds in proteins and peptides.

    abstract::For many proteins and peptides, disulfide bridges are prerequisite for their proper biological function. Many commercialized proteins are crosslinked by disulfide bridges that increase their resistance to destructive effects of extreme environment used in industrial processes or protect protein-based therapeutics from...

    journal_title:Biotechnology advances

    pub_type: 杂志文章,评审

    doi:10.1016/j.biotechadv.2004.09.002

    authors: Bulaj G

    更新日期:2005-01-01 00:00:00

  • Can a late bloomer become an early bird? Tools for flowering time adjustment.

    abstract::The transition from the vegetative to reproductive stage followed by inflorescence is a critical step in plant life; therefore, studies of the genes that influence flowering time have always been of great interest to scientists. Flowering is a process controlled by many genes interacting mutually in a genetic network,...

    journal_title:Biotechnology advances

    pub_type: 杂志文章,评审

    doi:10.1016/j.biotechadv.2013.09.008

    authors: Milec Z,Valárik M,Bartoš J,Safář J

    更新日期:2014-01-01 00:00:00

  • Expression of proteins encoded by foreign genes in Saccharomyces cerevisiae.

    abstract::The yeast, Saccharomyces cerevisiae is currently used for the production of recombinant DNA-generated proteins derived from a variety of eukaryotic organisms. The applications of a yeast-based technology in the production of proteins for pharmaceutical and industrial purposes is discussed including current methods for...

    journal_title:Biotechnology advances

    pub_type: 杂志文章

    doi:10.1016/0734-9750(89)90357-1

    authors: Martin CE,Scheinbach S

    更新日期:1989-01-01 00:00:00

  • Microbial biotransformation of bioactive flavonoids.

    abstract::The bioactive flavonoids are considered as the most important phytochemicals in food, which exert a wide range of biological benefits for human being. Microbial biotransformation strategies for production of flavonoids have attracted considerable interest because they allow yielding novel flavonoids, which do not exis...

    journal_title:Biotechnology advances

    pub_type: 杂志文章,评审

    doi:10.1016/j.biotechadv.2014.10.012

    authors: Cao H,Chen X,Jassbi AR,Xiao J

    更新日期:2015-01-01 00:00:00

  • Ecological risk assessment of genetically modified crops based on cellular automata modeling.

    abstract::The assessment of ecological risk in genetically modified (GM) biological systems is critically important for decision-making and public acceptance. Cellular automata (CA) provide a potential modeling and simulation framework for representing relationships and interspecies interactions both temporally and spatially. I...

    journal_title:Biotechnology advances

    pub_type: 杂志文章

    doi:10.1016/j.biotechadv.2009.05.024

    authors: Yang J,Wang ZR,Yang DL,Yang Q,Yan J,He MF

    更新日期:2009-11-01 00:00:00

  • Bio-synthesis of food additives and colorants-a growing trend in future food.

    abstract::Food additives and colorants are extensively used in the food industry to improve food quality and safety during processing, storage and packing. Sourcing of these molecules is predominately through three means: extraction from natural sources, chemical synthesis, and bio-production, with the first two being the most ...

    journal_title:Biotechnology advances

    pub_type: 杂志文章,评审

    doi:10.1016/j.biotechadv.2020.107694

    authors: Sun L,Xin F,Alper HS

    更新日期:2021-01-01 00:00:00

  • Biosynthesis and biotechnological application of non-canonical amino acids: Complex and unclear.

    abstract::Compared with the better-studied canonical amino acids, the distribution, metabolism and functions of natural non-canonical amino acids remain relatively obscure. Natural non-canonical amino acids have been mainly discovered in plants as secondary metabolites that perform diversified physiological functions. Due to th...

    journal_title:Biotechnology advances

    pub_type: 杂志文章,评审

    doi:10.1016/j.biotechadv.2018.07.008

    authors: Zou H,Li L,Zhang T,Shi M,Zhang N,Huang J,Xian M

    更新日期:2018-11-15 00:00:00

  • Immobilized viable microbial cells: from the process to the proteome em leader or the cart before the horse.

    abstract::Biotechnological processes based on immobilized viable cells have developed rapidly over the last 30 years. For a long time, basic studies of the physiological behaviour of immobilized cells (IC) have remained in the shadow of the applications. Natural IC structures, i.e. biofilms, are being increasingly investigated ...

    journal_title:Biotechnology advances

    pub_type: 杂志文章,评审

    doi:10.1016/j.biotechadv.2004.06.003

    authors: Junter GA,Jouenne T

    更新日期:2004-11-01 00:00:00

  • Production, properties, and applications of endo-β-mannanases.

    abstract::The present review provides up-to-date information on the occurrence and methodologies used for producing and purifying endo-β-mannanases and a comprehensive comparison of their biochemical properties. The amalgamation of biochemical, molecular and structural biology approaches which have been used for understanding e...

    journal_title:Biotechnology advances

    pub_type: 杂志文章,评审

    doi:10.1016/j.biotechadv.2016.11.001

    authors: Srivastava PK,Kapoor M

    更新日期:2017-01-01 00:00:00

  • Self-assembly of partially hydrolysed alpha-lactalbumin.

    abstract::Hydrolysis of the whey protein alpha-lactalbumin with a specific serine protease has been shown to result in regular nanotubes of approximately 20 nm in outer diameter and reaching several mum in length. Tubular assembly depends on the concentration of protein as this determines how far the hydrolysis proceeds. A conc...

    journal_title:Biotechnology advances

    pub_type: 杂志文章,评审

    doi:10.1016/j.biotechadv.2007.07.006

    authors: Ipsen R,Otte J

    更新日期:2007-11-01 00:00:00

  • β-Galactosidases: A great tool for synthesizing galactose-containing carbohydrates.

    abstract::β-Galactosidases, an important class of glycosidases, naturally catalyze the hydrolysis of β-galactosidic bonds in oligosaccharides and polysaccharides. Traditionally, these enzymes have been used to degrade lactose in dairy products, which are beneficial for lactose-intolerant people. Attractively, β-galactosidases e...

    journal_title:Biotechnology advances

    pub_type: 杂志文章,评审

    doi:10.1016/j.biotechadv.2019.107465

    authors: Lu L,Guo L,Wang K,Liu Y,Xiao M

    更新日期:2020-01-01 00:00:00

  • Enzymes revolutionize the bioproduction of value-added compounds: From enzyme discovery to special applications.

    abstract::Competitive sustainable production in industry demands new and better biocatalysts, optimized bioprocesses and cost-effective product recovery. Our review sheds light on the progress made for the individual steps towards these goals, starting with the discovery of new enzymes and their corresponding genes. The enzymes...

    journal_title:Biotechnology advances

    pub_type: 杂志文章,评审

    doi:10.1016/j.biotechadv.2020.107520

    authors: Wiltschi B,Cernava T,Dennig A,Galindo Casas M,Geier M,Gruber S,Haberbauer M,Heidinger P,Herrero Acero E,Kratzer R,Luley-Goedl C,Müller CA,Pitzer J,Ribitsch D,Sauer M,Schmölzer K,Schnitzhofer W,Sensen CW,Soh J,Steine

    更新日期:2020-01-01 00:00:00

  • Marine biotechnology advances towards applications in new functional foods.

    abstract::The marine ecosystem is still an untapped reservoir of biologically active compounds, which have considerable potential to supply food ingredients towards development of new functional foods. With the goal of increasing the availability and chemical diversity of functional marine ingredients, much research has been de...

    journal_title:Biotechnology advances

    pub_type: 杂志文章,评审

    doi:10.1016/j.biotechadv.2012.03.006

    authors: Freitas AC,Rodrigues D,Rocha-Santos TA,Gomes AM,Duarte AC

    更新日期:2012-11-01 00:00:00

  • A review of thermal-chemical conversion of lignocellulosic biomass in China.

    abstract::Biomass, a renewable, sustainable and carbon dioxide neutral resource, has received widespread attention in the energy market as an alternative to fossil fuels. Thermal-chemical conversion of biomass to produce biofuels is a promising technology with many commercial applications. This paper reviewed the state-of-the-a...

    journal_title:Biotechnology advances

    pub_type: 杂志文章

    doi:10.1016/j.biotechadv.2012.01.016

    authors: Ma L,Wang T,Liu Q,Zhang X,Ma W,Zhang Q

    更新日期:2012-07-01 00:00:00

  • Biosensors: recent trends.

    abstract::One of the major bottlenecks in automation and process control of industrial bioprocesses is the lack of suitable sensing devices to accurately measure the concentrations of biomolecules. The measurement of ions (e.g., H(+), NH(4)(+)) and gases (e.g., O(2), CO(2), NH(3)) using standard ion-selective and gas sensing el...

    journal_title:Biotechnology advances

    pub_type: 杂志文章

    doi:10.1016/0734-9750(85)90292-7

    authors: Graham A,Moo-Young M

    更新日期:1985-01-01 00:00:00

  • Biotransformation of sterols: selective cleavage of the side chain.

    abstract::This review elaborates on the recent development of microbial sterol biotransformation systems. Particular emphasis is laid on the new enzymatic approach investigating the cleavage of sterol side chain. New developments in the area of immobilized cell system and use of organic media along with recent reviews on side c...

    journal_title:Biotechnology advances

    pub_type: 杂志文章

    doi:10.1016/0734-9750(92)91351-e

    authors: Ahmad S,Garg SK,Johri BN

    更新日期:1992-01-01 00:00:00

  • Software tools for identification, visualization and analysis of protein tunnels and channels.

    abstract::Protein structures contain highly complex systems of voids, making up specific features such as surface clefts or grooves, pockets, protrusions, cavities, pores or channels, and tunnels. Many of them are essential for the migration of solvents, ions and small molecules through proteins, and their binding to the functi...

    journal_title:Biotechnology advances

    pub_type: 杂志文章,评审

    doi:10.1016/j.biotechadv.2012.02.002

    authors: Brezovsky J,Chovancova E,Gora A,Pavelka A,Biedermannova L,Damborsky J

    更新日期:2013-01-01 00:00:00

  • Ashbya gossypii beyond industrial riboflavin production: A historical perspective and emerging biotechnological applications.

    abstract::The filamentous fungus Ashbya gossypii has been safely and successfully used for more than two decades in the commercial production of riboflavin (vitamin B2). Its industrial relevance combined with its high genetic similarity with Saccharomyces cerevisiae together promoted the accumulation of fundamental knowledge th...

    journal_title:Biotechnology advances

    pub_type: 杂志文章,评审

    doi:10.1016/j.biotechadv.2015.10.001

    authors: Aguiar TQ,Silva R,Domingues L

    更新日期:2015-12-01 00:00:00

  • Complete microscale profiling of tumor microangiogenesis: a microradiological methodology reveals fundamental aspects of tumor angiogenesis and yields an array of quantitative parameters for its characterization.

    abstract::Complete profiling would substantially facilitate the fundamental understanding of tumor angiogenesis and of possible anti-angiogenesis cancer treatments. We developed an integrated synchrotron-based methodology with excellent performances: detection of very small vessels by high spatial resolution (~1 μm) and nanopar...

    journal_title:Biotechnology advances

    pub_type: 杂志文章

    doi:10.1016/j.biotechadv.2011.12.001

    authors: Chien CC,Kempson IM,Wang CL,Chen HH,Hwu Y,Chen NY,Lee TK,Tsai KK,Liu MS,Chang KY,Yang CS,Margaritondo G

    更新日期:2013-05-01 00:00:00

  • The production of biopharmaceuticals in plant systems.

    abstract::Biopharmaceuticals present the fastest growing segment in the pharmaceutical industry, with an ever widening scope of applications. Whole plants as well as contained plant cell culture systems are being explored for their potential as cheap, safe, and scalable production hosts. The first plant-derived biopharmaceutica...

    journal_title:Biotechnology advances

    pub_type: 杂志文章,评审

    doi:10.1016/j.biotechadv.2009.07.002

    authors: Karg SR,Kallio PT

    更新日期:2009-11-01 00:00:00

  • Advances in the diagnosis of key gastrointestinal nematode infections of livestock, with an emphasis on small ruminants.

    abstract::Parasitic nematodes (roundworms) of livestock have major economic impact globally. In spite of the diseases caused by these nematodes and some advances in the design of new therapeutic agents (anthelmintics) and attempts to develop vaccines against some of them, there has been limited progress in the establishment of ...

    journal_title:Biotechnology advances

    pub_type: 杂志文章,评审

    doi:10.1016/j.biotechadv.2013.01.008

    authors: Roeber F,Jex AR,Gasser RB

    更新日期:2013-12-01 00:00:00

  • Spotlight on biodiversity of microbial cell factories for glycerol conversion.

    abstract::Plant oil based industrial oleochemistry leads to a large side stream of crude glycerol, which offers itself as a low price carbon source for microbial chemical production. Compared to sugar, glycerol is more reduced and less microorganisms are able to use it as carbon source. An interesting feature of glycerol conver...

    journal_title:Biotechnology advances

    pub_type: 杂志文章,评审

    doi:10.1016/j.biotechadv.2019.05.001

    authors: Russmayer H,Egermeier M,Kalemasi D,Sauer M

    更新日期:2019-11-01 00:00:00

  • Versatile roles of plant NADPH oxidases and emerging concepts.

    abstract::NADPH oxidase (NOX) is a key player in the network of reactive oxygen species (ROS) producing enzymes. It catalyzes the production of superoxide (O2(-)), that in turn regulates a wide range of biological functions in a broad range of organisms. Plant Noxes are known as respiratory burst oxidase homologs (Rbohs) and ar...

    journal_title:Biotechnology advances

    pub_type: 杂志文章,评审

    doi:10.1016/j.biotechadv.2014.02.002

    authors: Kaur G,Sharma A,Guruprasad K,Pati PK

    更新日期:2014-05-01 00:00:00

  • Biotechnological routes based on lactic acid production from biomass.

    abstract::Lactic acid, the most important hydroxycarboxylic acid, is now commercially produced by the fermentation of sugars present in biomass. In addition to its use in the synthesis of biodegradable polymers, lactic acid can be regarded as a feedstock for the green chemistry of the future. Different potentially useful chemic...

    journal_title:Biotechnology advances

    pub_type: 杂志文章,评审

    doi:10.1016/j.biotechadv.2011.07.022

    authors: Gao C,Ma C,Xu P

    更新日期:2011-11-01 00:00:00

  • Biocatalytic transformation of nucleoside derivatives.

    abstract::Nucleoside derivatives are a class of compounds that have attracted intense interest in biotechnology and medicine. Use of biocatalysts opens exciting opportunities for selective synthesis of many nucleoside derivatives, and such an approach offers simplicity, exquisite selectivity and environmentally benign processes...

    journal_title:Biotechnology advances

    pub_type: 杂志文章,评审

    doi:10.1016/j.biotechadv.2010.01.006

    authors: Li N,Smith TJ,Zong MH

    更新日期:2010-05-01 00:00:00

  • Genetic modification of critical enzymes and involved genes in butanol biosynthesis from biomass.

    abstract::Interest in biobutanol, a sustainable vehicle fuel, is increasing due to rising oil prices and concerns of surrounding climate change and the energy crisis. However, the costs of biobutanol with conventional ABE fermentation by Clostridium are higher than the cost of butanol from today's petrochemical processes. Two m...

    journal_title:Biotechnology advances

    pub_type: 杂志文章,评审

    doi:10.1016/j.biotechadv.2010.05.015

    authors: Huang H,Liu H,Gan YR

    更新日期:2010-09-01 00:00:00

  • DNA microarrays for detecting endocrine-disrupting compounds.

    abstract::It has recently been discovered that a number of synthetic chemicals and naturally occurring compounds released into the environment can influence endocrine activity. These endocrine-disrupting compounds (EDCs) are highly varied in structure, provenance, and mode of action (MOA). Many EDCs are anthropogenic, products ...

    journal_title:Biotechnology advances

    pub_type: 杂志文章,评审

    doi:10.1016/j.biotechadv.2003.08.005

    authors: Francois E,Wang DY,Fulthorpe R,Liss SN,Edwards EA

    更新日期:2003-12-01 00:00:00

  • Circulating tumor cell isolation, culture, and downstream molecular analysis.

    abstract::Circulating tumor cells (CTCs) are a major contributor of cancer metastases and hold a promising prognostic significance in cancer detection. Performing functional and molecular characterization of CTCs provides an in-depth knowledge about this lethal disease. Researchers are making efforts to design devices and devel...

    journal_title:Biotechnology advances

    pub_type: 杂志文章,评审

    doi:10.1016/j.biotechadv.2018.03.007

    authors: Sharma S,Zhuang R,Long M,Pavlovic M,Kang Y,Ilyas A,Asghar W

    更新日期:2018-01-01 00:00:00

  • RNAi therapeutic and its innovative biotechnological evolution.

    abstract::Recently, United States Food and Drug Administration (FDA) and European Commission (EC) approved Alnylam Pharmaceuticals' RNA interference (RNAi) therapeutic, ONPATTRO™ (Patisiran), for the treatment of the polyneuropathy of hereditary transthyretin-mediated (hATTR) amyloidosis in adults. This is the first RNAi therap...

    journal_title:Biotechnology advances

    pub_type: 杂志文章,评审

    doi:10.1016/j.biotechadv.2019.04.012

    authors: Weng Y,Xiao H,Zhang J,Liang XJ,Huang Y

    更新日期:2019-01-01 00:00:00

  • Operational parameters for packed beds in solid-state cultivation.

    abstract::Packed bed cultivation systems have potential for widespread application in solid-state cultivation (SSC), but they are poorly characterized. The effects of particle size and substrate loading on the growth of Rhizopus oligosporus on sago-beads in packed bed bioreactors were investigated. Pressure drop and protein wer...

    journal_title:Biotechnology advances

    pub_type: 杂志文章

    doi:10.1016/0734-9750(93)90029-m

    authors: Gumbira-Sa'id E,Greenfield PF,Mitchell DA,Doelle HW

    更新日期:1993-01-01 00:00:00