Expression of proteins encoded by foreign genes in Saccharomyces cerevisiae.

abstract：:Traditional technologies are required to meet specific, quantitative standards of safety and performance. In tissue engineering, similar standards will have to be developed to enable routine clinical use and customized tissue fabrication. In this essay, we discuss a framework of concepts leading towards general design...

journal_title：Biotechnology advances

authors： Nawroth JC,Parker KK

更新日期：2013-09-01 00:00:00

abstract：:2-Phenylethanol (2-PE) is an important aromatic alcohol with a rose-like fragrance. It has been widely applied in the cosmetic, perfume, and food industries and is mainly produced by chemical synthesis. An alternative method for the production of natural flavors and fragrances is the microbial transformation process, ...

journal_title：Biotechnology advances

authors： Hua D,Xu P

更新日期：2011-11-01 00:00:00

abstract：:Due to the over-harvesting and deterioration of wild populations, the ever-growing crustacean market is increasingly reliant on aquaculture, driving the need for better management techniques. Since most cultured crustacean species exhibit sexually dimorphic growth patterns, the culture of monosex populations (either a...

journal_title：Biotechnology advances

authors： Ventura T,Sagi A

更新日期：2012-11-01 00:00:00

abstract：:Basic and applied research on microbial cellulases, hemicellulases and pectinases has not only generated significant scientific knowledge but has also revealed their enormous potential in biotechnology. At present, cellulases and related enzymes are used in food, brewery and wine, animal feed, textile and laundry, pul...

journal_title：Biotechnology advances

authors： Bhat MK

更新日期：2000-08-01 00:00:00

abstract：:The world population now is 6.7 billion and is predicted to reach 9 billion by 2050. Such a rapid growing population has tremendously increased the challenge for food security. Obviously, it is impossible for traditional agriculture to ensure the food security, while plant biotechnology offers considerable potential t...

journal_title：Biotechnology advances

authors： Wang B,Zhang Z,Yin Z,Feng C,Wang Q

更新日期：2012-05-01 00:00:00

abstract：:Despite their widespread use in patients with acute myocardial infarction, all currently available thrombolytic agents suffer from a number of significant limitations, including resistance to reperfusion, the occurrence of acute coronary reocclusion and bleeding complications. Furthermore, the therapeutic use of plasm...

journal_title：Biotechnology advances

authors： Lijnen HR,Collen D

更新日期：1993-01-01 00:00:00

abstract：:The concept of the Truncated Light-harvesting chlorophyll Antenna (TLA) size, as a tool by which to maximize sunlight utilization and photosynthetic productivity in microalgal mass cultures or high-density plant canopies, is discussed. TLA technology is known to improve sunlight-to-product energy conversion efficienci...

journal_title：Biotechnology advances

authors： Kirst H,Melis A

更新日期：2014-01-01 00:00:00

abstract：:Integrins are cell adhesion receptors predominantly important during normal and tumor angiogenesis. A sequence present on several extracellular matrix proteins composed of Arg-Gly-Asp (RGD) has attracted attention due to its role in cell adhesion mediated by integrins. The development of ligands that can bind to integ...

journal_title：Biotechnology advances

authors： Rocha LA,Learmonth DA,Sousa RA,Salgado AJ

更新日期：2018-01-01 00:00:00

abstract：:Cell-free protein synthesis systems enable the direct in vitro expression of proteins from template DNA or RNA. Use of biochemical and bioengineering techniques has greatly improved the yields and productivities of cell-free systems. In some cases, the yields approach the in vivo levels. Moreover, in vitro systems are...

journal_title：Biotechnology advances

authors： Nakano H,Yamane T

更新日期：1998-03-01 00:00:00

abstract：:Complete profiling would substantially facilitate the fundamental understanding of tumor angiogenesis and of possible anti-angiogenesis cancer treatments. We developed an integrated synchrotron-based methodology with excellent performances: detection of very small vessels by high spatial resolution (~1 μm) and nanopar...

journal_title：Biotechnology advances

authors： Chien CC,Kempson IM,Wang CL,Chen HH,Hwu Y,Chen NY,Lee TK,Tsai KK,Liu MS,Chang KY,Yang CS,Margaritondo G

更新日期：2013-05-01 00:00:00

abstract：:There is considerable interest in recent years in the bioconversion of forestry and agricultural residues into ethanol and value-added chemicals. High ethanol yields from lignocellulosic residues are dependent on efficient use of all the available sugars including glucose and xylose. The well-known fermentative yeast ...

journal_title：Biotechnology advances

authors： Chu BC,Lee H

更新日期：2007-09-01 00:00:00

abstract：:Aerobic granulation is drawing increasing global interest in a quest for an efficient and innovative technology in wastewater treatment. Developed less than two decades ago, extensive research work on aerobic granulation has been reported. The instability of the granule, which is one of the main problems that hinder p...

journal_title：Biotechnology advances

authors： Lee DJ,Chen YY,Show KY,Whiteley CG,Tay JH

更新日期：2010-11-01 00:00:00

abstract：:Enzyme immobilization is a well-known technique that allows the reuse of the biocatalyst and generally improves its stability. These improved characteristics are of fundamental importance to turn industrial biocatalysis into viable and competitive processes. The immobilization of enzymes can occur through several phys...

journal_title：Biotechnology advances

authors： Mulinari J,Oliveira JV,Hotza D

更新日期：2020-01-01 00:00:00

abstract：:Dinoflagellate microalgae are an important source of marine biotoxins. Bioactives from dinoflagellates are attracting increasing attention because of their impact on the safety of seafood and potential uses in biomedical, toxicological and pharmacological research. Here we review the potential applications of dinoflag...

journal_title：Biotechnology advances

authors： Gallardo-Rodríguez J,Sánchez-Mirón A,García-Camacho F,López-Rosales L,Chisti Y,Molina-Grima E

更新日期：2012-11-01 00:00:00

abstract：:Although natural sources have long been exploited for astaxanthin production, it is still uncertain if natural astaxanthin can be produced at lower cost than that of synthetic astaxanthin or not. In order to give a comprehensive cost analysis of astaxanthin production from Haematococcus, a pilot plant with two large s...

journal_title：Biotechnology advances

authors： Li J,Zhu D,Niu J,Shen S,Wang G

更新日期：2011-11-01 00:00:00

abstract：:New developments in magnetic labelling techniques for cells and microspheres have extended the useful range of magnetic separation, particularly high gradient magnetic separation, into biotechnical areas. The basic magnetic principles involved are reviewed and representative samples of labelling techniques and results...

journal_title：Biotechnology advances

authors： Dunlop EH,Feiler WA,Mattione MJ

更新日期：1984-01-01 00:00:00

abstract：:Both prokaryotes and eukaryotes have pyramid-shaped hierarchical regulatory networks that control gene transcription, enabling the cell to respond to natural environmental changes. In recent years, manipulation and engineering of transcriptional regulatory proteins and networks have been used to elicit microbial toler...

journal_title：Biotechnology advances

authors： Lin Z,Zhang Y,Wang J

更新日期：2013-11-01 00:00:00

abstract：:The realization of rapid, sensitive, and specific methods to detect foodborne pathogenic bacteria is central to implementing effective practice to ensure food safety and security. As a principle of transduction, the impedance technique has been applied in the field of microbiology as a means to detect and/or quantify ...

journal_title：Biotechnology advances

authors： Yang L,Bashir R

更新日期：2008-03-01 00:00:00

abstract：:DNA vaccination has been widely explored to develop new, alternative and efficient vaccines for cancer immunotherapy. DNA vaccines offer several benefits such as specific targeting, use of multiple genes to enhance immunity and reduced risk compared to conventional vaccines. Rapid developments in molecular biology and...

journal_title：Biotechnology advances

authors： Iurescia S,Fioretti D,Fazio VM,Rinaldi M

更新日期：2012-01-01 00:00:00

abstract：:Dihydroxyacetone is extensively used in cosmetic industry as an artificial suntan besides having clinical and biological applications. Thus, it is important to meet the commercial demand of dihydroxyacetone at an economical and qualitative level. Microbial route of production is found to be more favorable for dihydrox...

journal_title：Biotechnology advances

authors： Mishra R,Jain SR,Kumar A

更新日期：2008-07-01 00:00:00

abstract：:Recent progress in metabolic engineering and synthetic biology has enabled the production of valuable chemicals in microbial cell factories from renewable feedstocks. High value-added aromatic compounds, most of which are traditionally chemically synthesized from petroleum-derived feedstocks, represent a large class o...

journal_title：Biotechnology advances

authors： Li M,Liu C,Yang J,Nian R,Xian M,Li F,Zhang H

更新日期：2020-01-01 00:00:00

abstract：:The kinetic resolution of racemates and desymmetrization are the most common approaches to the preparation of enantiomerically enriched compounds. These procedures allow the access of high valuable, chiral building blocks for many purposes in academic or industrial R&D endeavors. Nevertheless, the scope of stereochemi...

journal_title：Biotechnology advances

authors： Cunha RL,Ferreira EA,Oliveira CS,Omori ÁT

更新日期：2015-09-01 00:00:00

abstract：:Pichia pastoris, a methylotrophic yeast, is an established system for the production of heterologous proteins, particularly biopharmaceuticals and industrial enzymes. To maximise and optimise the production of recombinant products, recent molecular research has focused on numerous issues including the design of expres...

journal_title：Biotechnology advances

authors： Looser V,Bruhlmann B,Bumbak F,Stenger C,Costa M,Camattari A,Fotiadis D,Kovar K

更新日期：2015-11-01 00:00:00

abstract：:Over the past decade, L-homophenylalanine is extensively used in the pharmaceutical industry as a precursor for production of angiotensin-converting enzyme (ACE) inhibitor, which possesses significant clinical application in the management of hypertension and congestive heart failure (CHF). A number of chemical method...

journal_title：Biotechnology advances

authors： Ahmad AL,Oh PC,Abd Shukor SR

更新日期：2009-05-01 00:00:00

abstract：:Surface display systems have been developed to express target molecules on almost all types of biological entities from viruses to mammalian cells and on a variety of synthetic particles. Various approaches have been developed to achieve the display of many different target molecules, aiming at several technological a...

journal_title：Biotechnology advances

authors： Ricca E,Baccigalupi L,Isticato R

更新日期：2020-12-31 00:00:00

abstract：:Enzymes are essential and ubiquitous biocatalysts involved in various metabolic pathways and used in many industrial processes. Here, we reframe enzymes not just as biocatalysts transforming bioproducts but also as sensitive probes for exploring the structure and composition of complex bioproducts, like meat tissue, d...

journal_title：Biotechnology advances

authors： Bourlieu C,Astruc T,Barbe S,Berrin JG,Bonnin E,Boutrou R,Hugouvieux V,Le Feunteun S,Paës G

更新日期：2020-01-01 00:00:00

abstract：:Plant cell suspension culture (PCSC) has emerged as a viable technology to produce plant specialized metabolites (PSM). While Taxol® and ginsenoside are two examples of successfully commercialized PCSC-derived PSM, widespread utilization of the PCSC platform has yet to be realized primarily due to a lack of understand...

journal_title：Biotechnology advances

authors： Arya SS,Rookes JE,Cahill DM,Lenka SK

更新日期：2020-12-01 00:00:00

abstract：:Human immunodeficiency virus (HIV) remains a worldwide health problem despite huge investments and research breakthroughs, and no single drug is effective in killing the virus yet. Among new strategies to control HIV infection, the phage display (PD) technology has become a promising tool in the discovery of peptides ...

journal_title：Biotechnology advances

authors： Lopes RS,Queiroz MAF,Gomes STM,Vallinoto ACR,Goulart LR,Ishak R

更新日期：2018-11-15 00:00:00

abstract：:The present review provides up-to-date information on the occurrence and methodologies used for producing and purifying endo-β-mannanases and a comprehensive comparison of their biochemical properties. The amalgamation of biochemical, molecular and structural biology approaches which have been used for understanding e...

journal_title：Biotechnology advances

authors： Srivastava PK,Kapoor M

更新日期：2017-01-01 00:00:00

abstract：:Cryptosporidium parvum is an obligate protozoan parasite responsible for the diarrheal illness cryptosporidiosis in humans and animals. Although C. parvum is particularly pathogenic in immunocompromised hosts, the molecular mechanisms by which C. parvum invades the host epithelial cells are not well understood. Charac...

journal_title：Biotechnology advances

authors： Boulter-Bitzer JI,Lee H,Trevors JT

更新日期：2007-01-01 00:00:00