Cellulases and related enzymes in biotechnology.

abstract：:Collagens are a family of at least 30 protein types organized as networks. They constitute the main support material of cells under the form of extracellular matrix as well as for membranes in vessels, organs, and tissue compartments. Collagen network abnormalities are at the origin of many diseases, including myopath...

journal_title：Biotechnology advances

authors： Noreen R,Moenner M,Hwu Y,Petibois C

更新日期：2012-11-01 00:00:00

abstract：:Yeast strains Y1, Y4 and Y7 demonstrated high conversion efficiencies for sugars and high abilities to tolerate or metabolize inhibitors in dilute-acid lignocellulosic hydrolysates. Strains Y1 and Y4 completely consumed the glucose within 24 h in dilute-acid lignocellulosic hydrolysate during in situ detoxification, a...

journal_title：Biotechnology advances

authors： Tian S,Zhou G,Yan F,Yu Y,Yang X

更新日期：2009-09-01 00:00:00

abstract：:Hydrolysis of the whey protein alpha-lactalbumin with a specific serine protease has been shown to result in regular nanotubes of approximately 20 nm in outer diameter and reaching several mum in length. Tubular assembly depends on the concentration of protein as this determines how far the hydrolysis proceeds. A conc...

journal_title：Biotechnology advances

authors： Ipsen R,Otte J

更新日期：2007-11-01 00:00:00

abstract：:Osteochondral defect management and repair remain a significant challenge in orthopedic surgery. Osteochondral defects contain damage to both the articular cartilage as well as the underlying subchondral bone. In order to repair an osteochondral defect the needs of the bone, cartilage and the bone-cartilage interface ...

journal_title：Biotechnology advances

authors： Nukavarapu SP,Dorcemus DL

更新日期：2013-09-01 00:00:00

abstract：:In the wake of the success of aerobic granulation in sequential batch reactors (SBRs) for treating wastewater, attention is beginning to turn to continuous flow applications. This is a necessary step given the advantages of continuous flow treatment processes and the fact that the majority of full-scale wastewater tre...

journal_title：Biotechnology advances

authors： Kent TR,Bott CB,Wang ZW

更新日期：2018-01-01 00:00:00

abstract：:The increasing awareness of the energy-environment nexus is compelling the development of technologies that reduce environmental impacts during energy production as well as energy consumption during environmental remediation. Countries spend billions in pollution cleanup projects, and new technologies with low energy ...

journal_title：Biotechnology advances

authors： Wang H,Luo H,Fallgren PH,Jin S,Ren ZJ

更新日期：2015-05-01 00:00:00

abstract：:Product inhibition of cellulolytic enzymes affects the efficiency of the biocatalytic conversion of lignocellulosic biomass to ethanol and other valuable products. New strategies that focus on reactor designs encompassing product removal, notably glucose removal, during enzymatic cellulose conversion are required for ...

journal_title：Biotechnology advances

authors： Andrić P,Meyer AS,Jensen PA,Dam-Johansen K

更新日期：2010-05-01 00:00:00

abstract：:Porous aluminum oxide (PAO) is a ceramic formed by an anodization process of pure aluminum that enables the controllable assembly of exceptionally dense and regular nanopores in a planar membrane. As a consequence, PAO has a high porosity, nanopores with high aspect ratio, biocompatibility and the potential for high s...

journal_title：Biotechnology advances

authors： Ingham CJ,ter Maat J,de Vos WM

更新日期：2012-09-01 00:00:00

abstract：:Complete profiling would substantially facilitate the fundamental understanding of tumor angiogenesis and of possible anti-angiogenesis cancer treatments. We developed an integrated synchrotron-based methodology with excellent performances: detection of very small vessels by high spatial resolution (~1 μm) and nanopar...

journal_title：Biotechnology advances

authors： Chien CC,Kempson IM,Wang CL,Chen HH,Hwu Y,Chen NY,Lee TK,Tsai KK,Liu MS,Chang KY,Yang CS,Margaritondo G

更新日期：2013-05-01 00:00:00

abstract：:Mitochondrial DNA (mtDNA) mutations have been involved in disease, aging and cancer and furthermore exploited for evolutionary and forensic investigation. When investigating mtDNA mutations the peculiar aspects of mitochondrial genetics, such as heteroplasmy and threshold effect, require suitable approaches which must...

journal_title：Biotechnology advances

authors： Kurelac I,Lang M,Zuntini R,Calabrese C,Simone D,Vicario S,Santamaria M,Attimonelli M,Romeo G,Gasparre G

更新日期：2012-01-01 00:00:00

abstract：:Nucleoside derivatives are a class of compounds that have attracted intense interest in biotechnology and medicine. Use of biocatalysts opens exciting opportunities for selective synthesis of many nucleoside derivatives, and such an approach offers simplicity, exquisite selectivity and environmentally benign processes...

journal_title：Biotechnology advances

authors： Li N,Smith TJ,Zong MH

更新日期：2010-05-01 00:00:00

abstract：:The world population now is 6.7 billion and is predicted to reach 9 billion by 2050. Such a rapid growing population has tremendously increased the challenge for food security. Obviously, it is impossible for traditional agriculture to ensure the food security, while plant biotechnology offers considerable potential t...

journal_title：Biotechnology advances

authors： Wang B,Zhang Z,Yin Z,Feng C,Wang Q

更新日期：2012-05-01 00:00:00

abstract：:Ribosomally synthesized peptides with antimicrobial properties (antimicrobial peptides-AMPs) are produced by eukaryotes and prokaryotes and represent crucial components of their defense systems against microorganisms. Although they differ in structure, they are nearly all cationic and very often amphiphilic, which ref...

journal_title：Biotechnology advances

authors： Papagianni M

更新日期：2003-09-01 00:00:00

abstract：:The non-conventional oleaginous yeast Yarrowia lipolytica shows great industrial promise. It naturally produces certain compounds of interest but can also artificially generate non-native metabolites, thanks to an engineering process made possible by the significant expansion of a dedicated genetic toolbox. In this re...

journal_title：Biotechnology advances

authors： Larroude M,Rossignol T,Nicaud JM,Ledesma-Amaro R

更新日期：2018-12-01 00:00:00

abstract：:For both nitrogen and carbon metabolism there exist specific regulatory mechanisms to enable cells to assimilate a wide variety of nitrogen and carbon sources. Superimposed are regulatory circuits, the so called nitrogen and carbon catabolite regulation, to allow for selective use of "rich" sources first and "poor" so...

journal_title：Biotechnology advances

authors： Hütter R,Niederberger P

更新日期：1983-01-01 00:00:00

abstract：:In order to decrease carbon emissions and negative environmental impacts of various pollutants, biofuel/biochemical production should be promoted for replacing fossil-based industrial processes. Utilization of abundant lignocellulosic biomass as a feedstock has recently become an attractive option. In this review, we ...

journal_title：Biotechnology advances

authors： Tanaka T,Kondo A

更新日期：2015-11-15 00:00:00

abstract：:Yersinia pestis, the causative agent of bubonic and pneumonic plague, is an extremely virulent bacterium but there are currently no approved vaccines for protection against this organism. Plants represent an economical and safer alternative to fermentation-based expression systems for the production of therapeutic pro...

journal_title：Biotechnology advances

authors： Alvarez ML,Cardineau GA

更新日期：2010-01-01 00:00:00

abstract：:The high plasticity of the active-site cavity of cytochromes P450, permitting reactivity toward a vast array of compounds, makes these enzymes attractive targets for biotechnological application. Escalating attention in this area is driven by remarkable progress in the rational design by DNA shuffling of self-sufficie...

journal_title：Biotechnology advances

authors： Hlavica P

更新日期：2009-03-01 00:00:00

abstract：:Biopharmaceuticals present the fastest growing segment in the pharmaceutical industry, with an ever widening scope of applications. Whole plants as well as contained plant cell culture systems are being explored for their potential as cheap, safe, and scalable production hosts. The first plant-derived biopharmaceutica...

journal_title：Biotechnology advances

authors： Karg SR,Kallio PT

更新日期：2009-11-01 00:00:00

abstract：:Plant cell suspension culture (PCSC) has emerged as a viable technology to produce plant specialized metabolites (PSM). While Taxol® and ginsenoside are two examples of successfully commercialized PCSC-derived PSM, widespread utilization of the PCSC platform has yet to be realized primarily due to a lack of understand...

journal_title：Biotechnology advances

authors： Arya SS,Rookes JE,Cahill DM,Lenka SK

更新日期：2020-12-01 00:00:00

abstract：:Volatile organic compounds (VOCs) emitted to the environment highly probably result in ecological and health risks. Many biotechnologies for waste gases containing hydrophobic VOCs have been developed in recent years. However, these biological processes usually exhibit poor removal performances for hydrophobic VOCs du...

journal_title：Biotechnology advances

authors： Cheng Y,He H,Yang C,Zeng G,Li X,Chen H,Yu G

更新日期：2016-11-01 00:00:00

abstract：:Surface Enhanced Laser Desorption/Ionisation Time-of-Fight Mass Spectrometry (SELDI-TOF MS) is a technique by which protein profiles can be rapidly produced from a wide variety of biological samples. By employing chromatographic surfaces combined with the specificity and reproducibility of mass spectrometry it has all...

journal_title：Biotechnology advances

authors： Woolley JF,Al-Rubeai M

更新日期：2009-03-01 00:00:00

abstract：:Surface display systems have been developed to express target molecules on almost all types of biological entities from viruses to mammalian cells and on a variety of synthetic particles. Various approaches have been developed to achieve the display of many different target molecules, aiming at several technological a...

journal_title：Biotechnology advances

authors： Ricca E,Baccigalupi L,Isticato R

更新日期：2020-12-31 00:00:00

abstract：:Cyclodextrins (CDs) are a family of cyclic oligosaccharides that are composed of alpha-1,4-linked glucopyranose subunits. Cyclodextrins are produced from starch by enzymatic degradation. These macrocyclic carbohydrates with apolar internal cavities can form complexes with and solubilize many normally water-insoluble c...

journal_title：Biotechnology advances

authors： Singh M,Sharma R,Banerjee UC

更新日期：2002-12-01 00:00:00

abstract：:This review discusses peptide-based vaccines in breast cancer, immune responses and clinical outcomes, which include studies on animal models and phase I, phase I/II, phase II and phase III clinical trials. Peptide-based vaccines are powerful neoadjuvant immunotherapies that can directly target proteins expressed in t...

journal_title：Biotechnology advances

authors： Peres Lde P,da Luz FA,Pultz Bdos A,Brígido PC,de Araújo RA,Goulart LR,Silva MJ

更新日期：2015-12-01 00:00:00

abstract：:This work reviews applications of high added value molecules produced from microalgae. Older forms of valorization - health food and quality feed, polyunsaturated fatty acids, pigments, carbohydrates - are currently penetrating their markets. They are driven by desirable properties: texturer and dye for food industry,...

journal_title：Biotechnology advances

authors： Levasseur W,Perré P,Pozzobon V

更新日期：2020-01-01 00:00:00

abstract：:The concept of the Truncated Light-harvesting chlorophyll Antenna (TLA) size, as a tool by which to maximize sunlight utilization and photosynthetic productivity in microalgal mass cultures or high-density plant canopies, is discussed. TLA technology is known to improve sunlight-to-product energy conversion efficienci...

journal_title：Biotechnology advances

authors： Kirst H,Melis A

更新日期：2014-01-01 00:00:00

abstract：:Malolactic fermentation (MLF) in wine can be accomplished by relying on the natural microflora or by inducing through inoculation of a specific strain(s) of malolactic bacteria, primarily strains of Leuconostoc oenos. Problems with inducing MLF include intrinsic factors of the grape must such as pH, presence of sulfur...

journal_title：Biotechnology advances

authors： Edwards CG,Beelman RB

更新日期：1989-01-01 00:00:00

abstract：:The Vero cell line is considered the most used continuous cell line for the production of viral vectors and vaccines. Historically, it is the first cell line that was approved by the WHO for the production of human vaccines. Comprehensive experimental data on the production of many viruses using the Vero cell line can...

journal_title：Biotechnology advances

authors： Kiesslich S,Kamen AA

更新日期：2020-11-15 00:00:00

abstract：:Parasitic nematodes (roundworms) of livestock have major economic impact globally. In spite of the diseases caused by these nematodes and some advances in the design of new therapeutic agents (anthelmintics) and attempts to develop vaccines against some of them, there has been limited progress in the establishment of ...

journal_title：Biotechnology advances

authors： Roeber F,Jex AR,Gasser RB

更新日期：2013-12-01 00:00:00