Bacterial haloperoxidases and their role in secondary metabolism.

abstract：:For both nitrogen and carbon metabolism there exist specific regulatory mechanisms to enable cells to assimilate a wide variety of nitrogen and carbon sources. Superimposed are regulatory circuits, the so called nitrogen and carbon catabolite regulation, to allow for selective use of "rich" sources first and "poor" so...

journal_title：Biotechnology advances

authors： Hütter R,Niederberger P

更新日期：1983-01-01 00:00:00

abstract：:Medicinal plants are essential for improving human health, and around 75% of the population in developing countries relies mainly on herb-based medicines for health care. As the king of herb plants, ginseng has been used for nearly 5,000 years in the oriental and recently in western medicines. Among the compounds stud...

journal_title：Biotechnology advances

authors： Kim YJ,Zhang D,Yang DC

更新日期：2015-11-01 00:00:00

abstract：:Biotechnological processes based on immobilized viable cells have developed rapidly over the last 30 years. For a long time, basic studies of the physiological behaviour of immobilized cells (IC) have remained in the shadow of the applications. Natural IC structures, i.e. biofilms, are being increasingly investigated ...

journal_title：Biotechnology advances

authors： Junter GA,Jouenne T

更新日期：2004-11-01 00:00:00

abstract：:Hydrolysis of the whey protein alpha-lactalbumin with a specific serine protease has been shown to result in regular nanotubes of approximately 20 nm in outer diameter and reaching several mum in length. Tubular assembly depends on the concentration of protein as this determines how far the hydrolysis proceeds. A conc...

journal_title：Biotechnology advances

authors： Ipsen R,Otte J

更新日期：2007-11-01 00:00:00

abstract：:Selenium is an essential trace element needed for all living organisms. Despite its essentiality, selenium is a potential toxic element to natural ecosystems due to its bioaccumulation potential. Though selenium is found naturally in the earth's crust, especially in carbonate rocks and volcanic and sedimentary soils, ...

journal_title：Biotechnology advances

authors： Tan LC,Nancharaiah YV,van Hullebusch ED,Lens PNL

更新日期：2016-09-01 00:00:00

abstract：:Liquid formulation of therapeutic proteins is a maturing technology. Demand for products that are easy to use in the clinic or that are amenable to self-administration make a ready to use liquid formulation desirable. Most modern liquid formulations have a simple composition; comprising a buffer, a tonicity modifier, ...

journal_title：Biotechnology advances

authors： Falconer RJ

更新日期：2019-11-15 00:00:00

abstract：:There is nowadays no single fully satisfactory method for VOC removal from indoor air due to the difficulties linked to the very low concentration (microg m(-3) range), diversity, and variability at which VOCs are typically found in the indoor environment. Although biological methods have shown a certain potential for...

journal_title：Biotechnology advances

authors： Guieysse B,Hort C,Platel V,Munoz R,Ondarts M,Revah S

更新日期：2008-09-01 00:00:00

abstract：:Circulating tumor cells (CTCs) are a major contributor of cancer metastases and hold a promising prognostic significance in cancer detection. Performing functional and molecular characterization of CTCs provides an in-depth knowledge about this lethal disease. Researchers are making efforts to design devices and devel...

journal_title：Biotechnology advances

authors： Sharma S,Zhuang R,Long M,Pavlovic M,Kang Y,Ilyas A,Asghar W

更新日期：2018-01-01 00:00:00

abstract：:Surface display systems have been developed to express target molecules on almost all types of biological entities from viruses to mammalian cells and on a variety of synthetic particles. Various approaches have been developed to achieve the display of many different target molecules, aiming at several technological a...

journal_title：Biotechnology advances

authors： Ricca E,Baccigalupi L,Isticato R

更新日期：2020-12-31 00:00:00

abstract：:The aldopentose D-xylose is one of the most abundant sugars in plant biomass and its efficient microbial utilization is of fundamental importance in the overall bioconversion of lignocellulosic materials into liquid fuels and chemicals. The discovery of pentose-fermenting yeasts in the early 1980's led to world wide i...

journal_title：Biotechnology advances

authors： Webb SR,Lee H

更新日期：1990-01-01 00:00:00

abstract：:Although almost every U.S. pulp mill has a biological wastewater treatment system, these systems based on bacteria, are largely ineffective in the removal of color. For this reason, we have attempted to utilize Phanerochaete chrysosporium, a fungus known to degrade lignin, as the primary organism in a novel waste trea...

journal_title：Biotechnology advances

authors： Joyce TW,Chang H,Campbell AG Jr,Gerrard ED,Kirk TK

更新日期：1984-01-01 00:00:00

abstract：:Basic and applied research on microbial cellulases, hemicellulases and pectinases has not only generated significant scientific knowledge but has also revealed their enormous potential in biotechnology. At present, cellulases and related enzymes are used in food, brewery and wine, animal feed, textile and laundry, pul...

journal_title：Biotechnology advances

authors： Bhat MK

更新日期：2000-08-01 00:00:00

abstract：:The ability to use progenitor cells for regenerative medicine remains an evolving but elusive clinical goal. A serious obstacle towards widespread use of stem cells for tissue regeneration is the challenges that face these cells when they are placed in vivo into a wound for therapy. These environments are hypoxic, aci...

journal_title：Biotechnology advances

authors： Hyun JS,Tran MC,Wong VW,Chung MT,Lo DD,Montoro DT,Wan DC,Longaker MT

更新日期：2013-09-01 00:00:00

abstract：:Next generation sequencing is in the process of evolving from a technology used for research purposes to one which is applied in clinical diagnostics. Recently introduced high throughput and benchtop instruments offer fully automated sequencing runs at a lower cost per base and faster assay times. In turn, the complex...

journal_title：Biotechnology advances

authors： Hess JF,Kohl TA,Kotrová M,Rönsch K,Paprotka T,Mohr V,Hutzenlaub T,Brüggemann M,Zengerle R,Niemann S,Paust N

更新日期：2020-01-01 00:00:00

abstract：:Aptamers are short single-stranded nucleic acid sequences capable of binding to target molecules in a way similar to antibodies. Due to various advantages such as prolonged shelf life, low batch to batch variation, low/no immunogenicity, freedom to incorporate chemical modification for enhanced stability and targeting...

journal_title：Biotechnology advances

authors： Wang T,Chen C,Larcher LM,Barrero RA,Veedu RN

更新日期：2019-01-01 00:00:00

abstract：:Ribosomally synthesized peptides with antimicrobial properties (antimicrobial peptides-AMPs) are produced by eukaryotes and prokaryotes and represent crucial components of their defense systems against microorganisms. Although they differ in structure, they are nearly all cationic and very often amphiphilic, which ref...

journal_title：Biotechnology advances

authors： Papagianni M

更新日期：2003-09-01 00:00:00

abstract：:Product inhibition of cellulolytic enzymes affects the efficiency of the biocatalytic conversion of lignocellulosic biomass to ethanol and other valuable products. New strategies that focus on reactor designs encompassing product removal, notably glucose removal, during enzymatic cellulose conversion are required for ...

journal_title：Biotechnology advances

authors： Andrić P,Meyer AS,Jensen PA,Dam-Johansen K

更新日期：2010-05-01 00:00:00

abstract：:There is considerable interest in recent years in the bioconversion of forestry and agricultural residues into ethanol and value-added chemicals. High ethanol yields from lignocellulosic residues are dependent on efficient use of all the available sugars including glucose and xylose. The well-known fermentative yeast ...

journal_title：Biotechnology advances

authors： Chu BC,Lee H

更新日期：2007-09-01 00:00:00

abstract：:Yeast strains Y1, Y4 and Y7 demonstrated high conversion efficiencies for sugars and high abilities to tolerate or metabolize inhibitors in dilute-acid lignocellulosic hydrolysates. Strains Y1 and Y4 completely consumed the glucose within 24 h in dilute-acid lignocellulosic hydrolysate during in situ detoxification, a...

journal_title：Biotechnology advances

authors： Tian S,Zhou G,Yan F,Yu Y,Yang X

更新日期：2009-09-01 00:00:00

abstract：:NADPH oxidase (NOX) is a key player in the network of reactive oxygen species (ROS) producing enzymes. It catalyzes the production of superoxide (O2(-)), that in turn regulates a wide range of biological functions in a broad range of organisms. Plant Noxes are known as respiratory burst oxidase homologs (Rbohs) and ar...

journal_title：Biotechnology advances

authors： Kaur G,Sharma A,Guruprasad K,Pati PK

更新日期：2014-05-01 00:00:00

abstract：:Loxoscelism (the term used to define accidents by the bite of brown spiders) has been reported worldwide. Clinical manifestations following brown spider bites are frequently associated with skin degeneration, a massive inflammatory response at the injured region, intravascular hemolysis, platelet aggregation causing t...

journal_title：Biotechnology advances

authors： Senff-Ribeiro A,Henrique da Silva P,Chaim OM,Gremski LH,Paludo KS,Bertoni da Silveira R,Gremski W,Mangili OC,Veiga SS

更新日期：2008-05-01 00:00:00

abstract：:The world population now is 6.7 billion and is predicted to reach 9 billion by 2050. Such a rapid growing population has tremendously increased the challenge for food security. Obviously, it is impossible for traditional agriculture to ensure the food security, while plant biotechnology offers considerable potential t...

journal_title：Biotechnology advances

authors： Wang B,Zhang Z,Yin Z,Feng C,Wang Q

更新日期：2012-05-01 00:00:00

abstract：:Aerobic granulation is drawing increasing global interest in a quest for an efficient and innovative technology in wastewater treatment. Developed less than two decades ago, extensive research work on aerobic granulation has been reported. The instability of the granule, which is one of the main problems that hinder p...

journal_title：Biotechnology advances

authors： Lee DJ,Chen YY,Show KY,Whiteley CG,Tay JH

更新日期：2010-11-01 00:00:00

abstract：:The Vero cell line is considered the most used continuous cell line for the production of viral vectors and vaccines. Historically, it is the first cell line that was approved by the WHO for the production of human vaccines. Comprehensive experimental data on the production of many viruses using the Vero cell line can...

journal_title：Biotechnology advances

authors： Kiesslich S,Kamen AA

更新日期：2020-11-15 00:00:00

abstract：:The review assesses current status and attempts to forecast trends in the development of lectin biorecognition technology. The progressive trend is characterized scientometrically and reflects the current transient situation, when standard low-throughput lectin-based techniques are being replaced by a novel microarray...

journal_title：Biotechnology advances

authors： Gemeiner P,Mislovicová D,Tkác J,Svitel J,Pätoprstý V,Hrabárová E,Kogan G,Kozár T

更新日期：2009-01-01 00:00:00

abstract：:This review discusses peptide-based vaccines in breast cancer, immune responses and clinical outcomes, which include studies on animal models and phase I, phase I/II, phase II and phase III clinical trials. Peptide-based vaccines are powerful neoadjuvant immunotherapies that can directly target proteins expressed in t...

journal_title：Biotechnology advances

authors： Peres Lde P,da Luz FA,Pultz Bdos A,Brígido PC,de Araújo RA,Goulart LR,Silva MJ

更新日期：2015-12-01 00:00:00

abstract：:Surface Enhanced Laser Desorption/Ionisation Time-of-Fight Mass Spectrometry (SELDI-TOF MS) is a technique by which protein profiles can be rapidly produced from a wide variety of biological samples. By employing chromatographic surfaces combined with the specificity and reproducibility of mass spectrometry it has all...

journal_title：Biotechnology advances

authors： Woolley JF,Al-Rubeai M

更新日期：2009-03-01 00:00:00

abstract：:Although the history of the golden spice turmeric (Curcuma longa) goes back thousands of years, it is only within the past century that we learned about the chemistry of its active component, curcumin. More than 6000 articles published within the past two decades have discussed the molecular basis for the antioxidant,...

journal_title：Biotechnology advances

authors： Prasad S,Gupta SC,Tyagi AK,Aggarwal BB

更新日期：2014-11-01 00:00:00

abstract：:A major feature of twenty-first century medical research is the development of therapeutic strategies that use 'biologics' (large molecules, usually engineered proteins) and living cells instead of, or as well as, the small molecules that were the basis of pharmacology in earlier eras. The high power of these techniqu...

journal_title：Biotechnology advances

authors： Davies JA,Ireland S,Harding S,Sharman JL,Southan C,Dominguez-Monedero A

更新日期：2019-12-01 00:00:00

abstract：:Pichia pastoris, a methylotrophic yeast, is an established system for the production of heterologous proteins, particularly biopharmaceuticals and industrial enzymes. To maximise and optimise the production of recombinant products, recent molecular research has focused on numerous issues including the design of expres...

journal_title：Biotechnology advances

authors： Looser V,Bruhlmann B,Bumbak F,Stenger C,Costa M,Camattari A,Fotiadis D,Kovar K

更新日期：2015-11-01 00:00:00