Chilli peppers--a review on tissue culture and transgenesis.

abstract：:Within five years, the CRISPR-Cas system has emerged as the dominating tool for genome engineering, while also changing the speed and efficiency of metabolic engineering in conventional (Saccharomyces cerevisiae and Schizosaccharomyces pombe) and non-conventional (Yarrowia lipolytica, Pichia pastoris syn. Komagataella...

journal_title：Biotechnology advances

authors： Raschmanová H,Weninger A,Glieder A,Kovar K,Vogl T

更新日期：2018-01-01 00:00:00

abstract：:Integrins are cell adhesion receptors predominantly important during normal and tumor angiogenesis. A sequence present on several extracellular matrix proteins composed of Arg-Gly-Asp (RGD) has attracted attention due to its role in cell adhesion mediated by integrins. The development of ligands that can bind to integ...

journal_title：Biotechnology advances

authors： Rocha LA,Learmonth DA,Sousa RA,Salgado AJ

更新日期：2018-01-01 00:00:00

abstract：:Due to concerns about the unsustainability and predictable shortage of fossil feedstocks, research efforts are currently being made to develop new processes for production of commodities using alternative feedstocks. 3-Hydroxypropionic acid (CAS 503-66-2) was recognised by the US Department of Energy as one of the mos...

journal_title：Biotechnology advances

authors： de Fouchécour F,Sánchez-Castañeda AK,Saulou-Bérion C,Spinnler HÉ

更新日期：2018-01-01 00:00:00

abstract：:Recently, United States Food and Drug Administration (FDA) and European Commission (EC) approved Alnylam Pharmaceuticals' RNA interference (RNAi) therapeutic, ONPATTRO™ (Patisiran), for the treatment of the polyneuropathy of hereditary transthyretin-mediated (hATTR) amyloidosis in adults. This is the first RNAi therap...

journal_title：Biotechnology advances

authors： Weng Y,Xiao H,Zhang J,Liang XJ,Huang Y

更新日期：2019-01-01 00:00:00

abstract：:Fungi are notoriously prolific producers of secondary metabolites including nonribosomal peptides (NRPs). The structural complexity of NRPs grants them interesting activities such as antibiotic, anti-cancer, and anti-inflammatory properties. The discovery of these compounds with attractive activities can be achieved b...

journal_title：Biotechnology advances

authors： Vassaux A,Meunier L,Vandenbol M,Baurain D,Fickers P,Jacques P,Leclère V

更新日期：2019-12-01 00:00:00

abstract：:The marine ecosystem is still an untapped reservoir of biologically active compounds, which have considerable potential to supply food ingredients towards development of new functional foods. With the goal of increasing the availability and chemical diversity of functional marine ingredients, much research has been de...

journal_title：Biotechnology advances

authors： Freitas AC,Rodrigues D,Rocha-Santos TA,Gomes AM,Duarte AC

更新日期：2012-11-01 00:00:00

abstract：:The concept of the Truncated Light-harvesting chlorophyll Antenna (TLA) size, as a tool by which to maximize sunlight utilization and photosynthetic productivity in microalgal mass cultures or high-density plant canopies, is discussed. TLA technology is known to improve sunlight-to-product energy conversion efficienci...

journal_title：Biotechnology advances

authors： Kirst H,Melis A

更新日期：2014-01-01 00:00:00

abstract：:Direct interspecies electron transfer (DIET) via electrically conductive pili (e-pili) and c-type cytochrome between acetogens and methanogens has been proposed as an essential pathway for methane production. Supplements of conductive materials have been extensively found to promote methane production in microbial ana...

journal_title：Biotechnology advances

authors： Yin Q,Wu G

更新日期：2019-12-01 00:00:00

abstract：:The world population now is 6.7 billion and is predicted to reach 9 billion by 2050. Such a rapid growing population has tremendously increased the challenge for food security. Obviously, it is impossible for traditional agriculture to ensure the food security, while plant biotechnology offers considerable potential t...

journal_title：Biotechnology advances

authors： Wang B,Zhang Z,Yin Z,Feng C,Wang Q

更新日期：2012-05-01 00:00:00

abstract：:Malolactic fermentation (MLF) in wine can be accomplished by relying on the natural microflora or by inducing through inoculation of a specific strain(s) of malolactic bacteria, primarily strains of Leuconostoc oenos. Problems with inducing MLF include intrinsic factors of the grape must such as pH, presence of sulfur...

journal_title：Biotechnology advances

authors： Edwards CG,Beelman RB

更新日期：1989-01-01 00:00:00

abstract：:The kinetic resolution of racemates and desymmetrization are the most common approaches to the preparation of enantiomerically enriched compounds. These procedures allow the access of high valuable, chiral building blocks for many purposes in academic or industrial R&D endeavors. Nevertheless, the scope of stereochemi...

journal_title：Biotechnology advances

authors： Cunha RL,Ferreira EA,Oliveira CS,Omori ÁT

更新日期：2015-09-01 00:00:00

abstract：:Liquid formulation of therapeutic proteins is a maturing technology. Demand for products that are easy to use in the clinic or that are amenable to self-administration make a ready to use liquid formulation desirable. Most modern liquid formulations have a simple composition; comprising a buffer, a tonicity modifier, ...

journal_title：Biotechnology advances

authors： Falconer RJ

更新日期：2019-11-15 00:00:00

abstract：:Protein structures contain highly complex systems of voids, making up specific features such as surface clefts or grooves, pockets, protrusions, cavities, pores or channels, and tunnels. Many of them are essential for the migration of solvents, ions and small molecules through proteins, and their binding to the functi...

journal_title：Biotechnology advances

authors： Brezovsky J,Chovancova E,Gora A,Pavelka A,Biedermannova L,Damborsky J

更新日期：2013-01-01 00:00:00

abstract：:Over the past decade, L-homophenylalanine is extensively used in the pharmaceutical industry as a precursor for production of angiotensin-converting enzyme (ACE) inhibitor, which possesses significant clinical application in the management of hypertension and congestive heart failure (CHF). A number of chemical method...

journal_title：Biotechnology advances

authors： Ahmad AL,Oh PC,Abd Shukor SR

更新日期：2009-05-01 00:00:00

abstract：:"Molecular farming" in plants with significant advantages in cost and safety is touted as a promising platform for the production of complex pharmaceutical proteins. While whole-plant produced biopharmaceuticals account for a significant portion of the preclinical and clinical pipeline, plant cell suspension culture, ...

journal_title：Biotechnology advances

authors： Xu J,Ge X,Dolan MC

更新日期：2011-05-01 00:00:00

abstract：:This paper addresses the circumstances of germplasm contamination and updates on transmission of pathogenic agents by embryos produced in vitro and by associated techniques. It has been shown that some pathogenic agents might have been associated with the follicular oocytes and oviductal cells, collected for in vitro ...

journal_title：Biotechnology advances

authors： Bielanski A

更新日期：1997-01-01 00:00:00

abstract：:The biotech industry is, nowadays, facing unparalleled challenges due to the enhanced demand for biotechnology-based human therapeutic products, such as monoclonal antibodies (mAbs). This has led companies to improve substantially their upstream processes, with the yield of monoclonals increasing to titers never seen ...

journal_title：Biotechnology advances

authors： Rosa PA,Azevedo AM,Sommerfeld S,Bäcker W,Aires-Barros MR

更新日期：2011-11-01 00:00:00

abstract：:Due to the over-harvesting and deterioration of wild populations, the ever-growing crustacean market is increasingly reliant on aquaculture, driving the need for better management techniques. Since most cultured crustacean species exhibit sexually dimorphic growth patterns, the culture of monosex populations (either a...

journal_title：Biotechnology advances

authors： Ventura T,Sagi A

更新日期：2012-11-01 00:00:00

abstract：:In recent years the study of root phenotypic plasticity in response to sub-optimal environmental factors and the genetic control of these responses have received renewed attention. As a path to increased productivity, in particular for low fertility soils, several applied research projects worldwide target the improve...

journal_title：Biotechnology advances

authors： Postma JA,Schurr U,Fiorani F

更新日期：2014-01-01 00:00:00

abstract：:Basic and applied research on microbial cellulases, hemicellulases and pectinases has not only generated significant scientific knowledge but has also revealed their enormous potential in biotechnology. At present, cellulases and related enzymes are used in food, brewery and wine, animal feed, textile and laundry, pul...

journal_title：Biotechnology advances

authors： Bhat MK

更新日期：2000-08-01 00:00:00

abstract：:The filamentous fungus Ashbya gossypii has been safely and successfully used for more than two decades in the commercial production of riboflavin (vitamin B2). Its industrial relevance combined with its high genetic similarity with Saccharomyces cerevisiae together promoted the accumulation of fundamental knowledge th...

journal_title：Biotechnology advances

authors： Aguiar TQ,Silva R,Domingues L

更新日期：2015-12-01 00:00:00

abstract：:In order to decrease carbon emissions and negative environmental impacts of various pollutants, biofuel/biochemical production should be promoted for replacing fossil-based industrial processes. Utilization of abundant lignocellulosic biomass as a feedstock has recently become an attractive option. In this review, we ...

journal_title：Biotechnology advances

authors： Tanaka T,Kondo A

更新日期：2015-11-15 00:00:00

abstract：:New developments in magnetic labelling techniques for cells and microspheres have extended the useful range of magnetic separation, particularly high gradient magnetic separation, into biotechnical areas. The basic magnetic principles involved are reviewed and representative samples of labelling techniques and results...

journal_title：Biotechnology advances

authors： Dunlop EH,Feiler WA,Mattione MJ

更新日期：1984-01-01 00:00:00

abstract：:Pigments (mainly carotenoids) are important nutraceuticals known for their potent anti-oxidant activities and have been used extensively as high end health supplements. Microalgae are the most promising sources of natural carotenoids and are devoid of the toxic effects associated with synthetic derivatives. Compared t...

journal_title：Biotechnology advances

authors： Hu J,Nagarajan D,Zhang Q,Chang JS,Lee DJ

更新日期：2018-01-01 00:00:00

abstract：:Recent progress in metabolic engineering and synthetic biology has enabled the production of valuable chemicals in microbial cell factories from renewable feedstocks. High value-added aromatic compounds, most of which are traditionally chemically synthesized from petroleum-derived feedstocks, represent a large class o...

journal_title：Biotechnology advances

authors： Li M,Liu C,Yang J,Nian R,Xian M,Li F,Zhang H

更新日期：2020-01-01 00:00:00

abstract：:Bradyrhizobium elkanii produces rhizobitoxine, an enol-ether amino acid, which has been regarded as a phytotoxin because it causes chlorosis in soybeans. However, recent studies have revealed that rhizobitoxine plays a positive role in establishing symbiosis between B. elkanii and host legumes: rhizobitoxine enhances ...

journal_title：Biotechnology advances

authors： Sugawara M,Okazaki S,Nukui N,Ezura H,Mitsui H,Minamisawa K

更新日期：2006-07-01 00:00:00

abstract：:During a tempe fermentation the concentrations of linoleic, and alpha-linolenic acids (ALA) decreased while the concentration of oleic acid increased. During fatty acid synthesis Rhizopus sp. produced only gamma-linolenic acid (GLA) instead of ALA. The amount of GLA in tempe were influenced by varying external paramet...

journal_title：Biotechnology advances

authors： Bisping B,Hering L,Baumann U,Denter J,Keuth S,Rehm HJ

更新日期：1993-01-01 00:00:00

abstract：:Medicinal plants are essential for improving human health, and around 75% of the population in developing countries relies mainly on herb-based medicines for health care. As the king of herb plants, ginseng has been used for nearly 5,000 years in the oriental and recently in western medicines. Among the compounds stud...

journal_title：Biotechnology advances

authors： Kim YJ,Zhang D,Yang DC

更新日期：2015-11-01 00:00:00

abstract：:Microalgae are regarded as a potential biomass source for biofuel purposes. With regard to bioethanol production, microalgae seem to overcome traditional substrate drawbacks. Enzymatic activities are responsible for carbon allocation and hence for carbohydrate profiles. Enzyme activities may be manipulated by metaboli...

journal_title：Biotechnology advances

authors： González-Fernández C,Ballesteros M

更新日期：2012-11-01 00:00:00

abstract：:Gene delivery vectors must deliver their cargoes into the cytosol or the nucleus, where DNA or siRNA functions in vivo. Therefore it is crucial for the rational design of the nucleic acid delivery carriers. Compared with viral vectors, non-viral vectors have overcome some fatal defections in gene therapy. Whereas the ...

journal_title：Biotechnology advances

authors： Yang J,Liu H,Zhang X

更新日期：2014-07-01 00:00:00