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A Microbial Drugstore for Motility.

Abstract：

:While there is growing appreciation that the microbiome regulates gut-brain signaling, the underlying mechanisms remain elusive. In this issue of Cell Host & Microbe, Bhattarai et al. (2018) identify bacteria-derived tryptamine as a ligand for the gut-epithelium-expressed GPCR 5-HT4 receptor, thereby functioning as a regulator of gastrointestinal motility.

journal_name

Cell Host Microbe

journal_title

Cell host & microbe

authors

Cryan JF,Clarke G,Dinan TG,Schellekens H

doi

10.1016/j.chom.2018.05.020

subject

Has Abstract

pub_date

2018-06-13 00:00:00

pages

691-692

issue

6

eissn

1931-3128

issn

1934-6069

pii

S1931-3128(18)30274-9

journal_volume

23

pub_type

评论,杂志文章

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