IgA Summons IgG to Take a Hit at HIV-1.

Abstract:

:In this issue of Cell Host & Microbe, Jia et al. used a vesicular stomatitis virus-based probe to isolate B cells expressing broadly neutralizing HIV-1 antibodies. Besides identifying neutralizing epitopes, this study highlights potential protection afforded by IgA arising from either direct IgM-to-IgA or sequential IgM-to-IgG-to-IgA class switching.

journal_name

Cell Host Microbe

journal_title

Cell host & microbe

authors

Magri G,Cerutti A

doi

10.1016/j.chom.2020.05.017

subject

Has Abstract

pub_date

2020-06-10 00:00:00

pages

854-856

issue

6

eissn

1931-3128

issn

1934-6069

pii

S1931-3128(20)30299-7

journal_volume

27

pub_type

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