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NAGging Hexokinase PEPs up NLRP3.

Abstract：

:Recognition of peptidoglycan is integral to detection of gram-positive bacterial pathogens. In a recent issue of Cell, Wolf et al. (2016) report that detection of the N-acetylglucosamine component of peptidoglycan by the glycolytic enzyme hexokinase activates the NLRP3 inflammasome, revealing an intriguing interplay between pathogen detection and metabolism.

journal_name

Cell Host Microbe

journal_title

Cell host & microbe

authors

Hampton H,Hutcheon C,Subramanian N

doi

10.1016/j.chom.2016.07.017

subject

Has Abstract

pub_date

2016-08-10 00:00:00

pages

130-2

issue

2

eissn

1931-3128

issn

1934-6069

pii

S1931-3128(16)30316-X

journal_volume

20

pub_type

评论,杂志文章

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