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Viperin Poisons Viral Replication.

Abstract：

:Control of virus infection relies on the stimulation of interferon-stimulated genes (ISGs) that inhibit viral replication. In a recent Nature paper, Gizzi et al. (2018) discovered that the ISG viperin inhibits virus replication by generating the ribonucleotide ddhCTP, which interferes with RNA synthesis, thus offering insights into drug design.

journal_name

Cell Host Microbe

journal_title

Cell host & microbe

authors

Ng LFP,Hiscox JA

doi

10.1016/j.chom.2018.07.014

subject

Has Abstract

pub_date

2018-08-08 00:00:00

pages

181-183

issue

2

eissn

1931-3128

issn

1934-6069

pii

S1931-3128(18)30384-6

journal_volume

24

pub_type

评论,杂志文章

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