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Hedgehog: linking uracil to innate defense.

Abstract：

:The ability of the gut epithelium to defend against pathogens while tolerating harmless commensal organisms remains an important puzzle. In this issue of Cell Host & Microbe, Lee et al. (2015) reveal how pathogen-secreted uracil acts at two steps to induce ROS via the Hedgehog pathway.

journal_name

Cell Host Microbe

journal_title

Cell host & microbe

authors

Bier E,Nizet V

doi

10.1016/j.chom.2015.01.010

subject

Has Abstract

pub_date

2015-02-11 00:00:00

pages

146-8

issue

2

eissn

1931-3128

issn

1934-6069

pii

S1931-3128(15)00030-X

journal_volume

17

pub_type

评论,杂志文章

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