How do base-pairing small RNAs evolve?

Abstract:

:The increasing numbers of characterized base-pairing small RNAs (sRNAs) and the identification of these regulators in a broad range of bacteria are allowing comparisons between species and explorations of sRNA evolution. In this review, we describe some examples of trans-encoded base-pairing sRNAs that are species-specific and others that are more broadly distributed. We also describe examples of sRNA orthologs where different features are conserved. These examples provide the background for a discussion of mechanisms of sRNA evolution and selective pressures on the sRNAs and their mRNA target(s).

journal_name

FEMS Microbiol Rev

authors

Updegrove TB,Shabalina SA,Storz G

doi

10.1093/femsre/fuv014

subject

Has Abstract

pub_date

2015-05-01 00:00:00

pages

379-91

issue

3

eissn

0168-6445

issn

1574-6976

pii

fuv014

journal_volume

39

pub_type

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