Antibiotics in early life: dysbiosis and the damage done.

abstract：:It has become increasingly and widely recognised that bacteria do not exist as solitary cells, but are colonial organisms that exploit elaborate systems of intercellular communication to facilitate their adaptation to changing environmental conditions. The languages by which bacteria communicate take the form of chemi...

journal_title：FEMS microbiology reviews

authors： Whitehead NA,Barnard AM,Slater H,Simpson NJ,Salmond GP

更新日期：2001-08-01 00:00:00

abstract：:We review and update the work on genetic elements, e.g., viruses and plasmids (exluding IS elements and transposons) in the kingdom Crenarchaeota (Thermoproteales and Sulfolobales) and the orders Thermococcales and Thermoplasmales in the kingdom Euryarchaeota of the archael domain, including unpublished data from our ...

journal_title：FEMS microbiology reviews

authors： Zillig W,Prangishvilli D,Schleper C,Elferink M,Holz I,Albers S,Janekovic D,Götz D

更新日期：1996-05-01 00:00:00

abstract：:Heat-shock proteins (hsps) have been identified as molecular chaperones conserved between microbes and man and grouped by their molecular mass and high degree of amino acid homology. This article reviews the major hsps of Saccharomyces cerevisiae, their interactions with trehalose, the effect of fermentation and the r...

journal_title：FEMS microbiology reviews

authors： Burnie JP,Carter TL,Hodgetts SJ,Matthews RC

更新日期：2006-01-01 00:00:00

abstract：:Human protein kinase C (PKC) isoforms have been implicated in diseases such as Alzheimer's, diabetes and cancers. In contrast to mammals, which have at least nine genes, fungi have only one or two. The yeast Saccharomyces cerevisiae produces only a single Pkc1 and is employed in the study of specific human isozymes, i...

journal_title：FEMS microbiology reviews

authors： Heinisch JJ,Rodicio R

更新日期：2018-01-01 00:00:00

abstract：:Our knowledge regarding the nature and development of microbial biofilms has grown significantly since the first report of these communities by Antonie van Leeuwenhoek in the late 1600s. Nevertheless, most biofilm studies examine mono-species cultures, whereas nearly all biofilm communities in nature comprise a variet...

journal_title：FEMS microbiology reviews

authors： Elias S,Banin E

更新日期：2012-09-01 00:00:00

abstract：:Formate is a substrate, or product, of diverse reactions catalyzed by eukaryotic organisms, eubacteria, and archaebacteria. A survey of metabolic groups reveals that formate is a common growth substrate, especially among the anaerobic eubacteria and archaebacteria. Formate also functions as an accessory reductant for ...

journal_title：FEMS microbiology reviews

authors： Ferry JG

更新日期：1990-12-01 00:00:00

abstract：:Lipopeptides constitute a structurally diverse group of metabolites produced by various bacterial and fungal genera. In the past decades, research on lipopeptides has been fueled by their antimicrobial, antitumour, immunosuppressant and surfactant activities. However, the natural functions of lipopeptides in the lifes...

journal_title：FEMS microbiology reviews

authors： Raaijmakers JM,De Bruijn I,Nybroe O,Ongena M

更新日期：2010-11-01 00:00:00

abstract：:Antibiotic resistance is one of the few examples of evolution that can be addressed experimentally. The present review analyses this resistance, focusing on the networks that regulate its acquisition and its effect on bacterial physiology. It is widely accepted that antibiotics and antibiotic resistance genes play fun...

journal_title：FEMS microbiology reviews

authors： Martinez JL,Fajardo A,Garmendia L,Hernandez A,Linares JF,Martínez-Solano L,Sánchez MB

更新日期：2009-01-01 00:00:00

abstract：:Lack of known mechanisms of protection against Staphylococcus aureus in humans is hindering development of efficacious vaccines. Preclinical as well as clinical data suggest that antibodies play an important role against S. aureus. For instance, certain hypogammaglobulinaemic patients are at increased risk of staphylo...

journal_title：FEMS microbiology reviews

authors： Pozzi C,Lofano G,Mancini F,Soldaini E,Speziale P,De Gregorio E,Rappuoli R,Bertholet S,Grandi G,Bagnoli F

更新日期：2015-09-01 00:00:00

abstract：:The urogenital tract appears to be the only niche of the human body that shows clear differences in microbiota between men and women. The female reproductive tract has special features in terms of immunological organization, an epithelial barrier, microbiota, and influence by sex hormones such as estrogen. While the u...

journal_title：FEMS microbiology reviews

authors： Petrova MI,van den Broek M,Balzarini J,Vanderleyden J,Lebeer S

更新日期：2013-09-01 00:00:00

abstract：:Legionella pneumophila is naturally found in fresh water were the bacteria parasitize within protozoa. It also survives planctonically in water or biofilms. Upon aerosol formation via man-made water systems, L. pneumophila can enter the human lung and cause a severe form of pneumonia, called Legionnaires' disease. The...

journal_title：FEMS microbiology reviews

authors： Steinert M,Hentschel U,Hacker J

更新日期：2002-06-01 00:00:00

abstract：:A close symbiotic relationship exists between the intestinal microbiota and its host. A critical component of gut homeostasis is the presence of a mucus layer covering the gastrointestinal tract. Mucus is a viscoelastic gel at the interface between the luminal content and the host tissue that provides a habitat to the...

journal_title：FEMS microbiology reviews

authors： Etienne-Mesmin L,Chassaing B,Desvaux M,De Paepe K,Gresse R,Sauvaitre T,Forano E,de Wiele TV,Schüller S,Juge N,Blanquet-Diot S

更新日期：2019-09-01 00:00:00

abstract：:Purine salvage is an essential function for all obligate parasitic protozoa studied to date and most are also capable of efficient uptake of preformed pyrimidines. Much progress has been made in the identification and characterisation of protozoan purine and pyrimidine transporters. While the genes encoding protozoan ...

journal_title：FEMS microbiology reviews

authors： de Koning HP,Bridges DJ,Burchmore RJ

更新日期：2005-11-01 00:00:00

abstract：:Understanding the structure, functionalities and biology of functional amyloids is an issue of emerging interest. Inclusion bodies, namely protein clusters formed in recombinant bacteria during protein production processes, have emerged as unanticipated, highly tunable models for the scrutiny of the physiology and arc...

journal_title：FEMS microbiology reviews

authors： de Marco A,Ferrer-Miralles N,Garcia-Fruitós E,Mitraki A,Peternel S,Rinas U,Trujillo-Roldán MA,Valdez-Cruz NA,Vázquez E,Villaverde A

更新日期：2019-01-01 00:00:00

abstract：:Sequencing-based studies have illuminated increased transcriptional complexity within the genome structure of bacteria and have resulted in the identification of many small regulatory RNAs (sRNA) and a large amount of antisense transcription. It remains an open question whether these sRNAs all indeed play regulatory r...

journal_title：FEMS microbiology reviews

authors： Oliva G,Sahr T,Buchrieser C

更新日期：2015-05-01 00:00:00

abstract：:First insights on the human gut microbiome have been gained from medium-sized, cross-sectional studies. However, given the modest portion of explained variance of currently identified covariates and the small effect size of gut microbiota modulation strategies, upscaling seems essential for further discovery and chara...

journal_title：FEMS microbiology reviews

authors： Vandeputte D,Tito RY,Vanleeuwen R,Falony G,Raes J

更新日期：2017-08-01 00:00:00

abstract：:Microbial networks are an increasingly popular tool to investigate microbial community structure, as they integrate multiple types of information and may represent systems-level behaviour. Interpreting these networks is not straightforward, and the biological implications of network properties are unclear. Analysis of...

journal_title：FEMS microbiology reviews

authors： Röttjers L,Faust K

更新日期：2018-11-01 00:00:00

abstract：:Most bacteria pathogenic for humans have closely related nonpathogenic counterparts that live as saprophytes, commensals or even symbionts (mutualists) in similar or different habitats. The knowledge of how these bacteria adapt their metabolism to the preferred habitats is critical for our understanding of pathogenesi...

journal_title：FEMS microbiology reviews

authors： Fuchs TM,Eisenreich W,Heesemann J,Goebel W

更新日期：2012-03-01 00:00:00

abstract：:DNA microarrays are a powerful and promising approach to gain a detailed understanding of the bacterial response and the molecular cross-talk that can occur as a consequence of host-pathogen interactions. However, published studies mainly describe the host response to infection. Analysis of bacterial gene regulation i...

journal_title：FEMS microbiology reviews

authors： La MV,Raoult D,Renesto P

更新日期：2008-05-01 00:00:00

abstract：:Pathogenicity and symbiosis are central to bacteria-host interactions. Although several human pathogens have been subjected to functional genomic analysis, we still understand little about bacteria-invertebrate interactions despite their ecological prevalence. Advances in our knowledge of this area are often hindered ...

journal_title：FEMS microbiology reviews

authors： ffrench-Constant R,Waterfield N,Daborn P,Joyce S,Bennett H,Au C,Dowling A,Boundy S,Reynolds S,Clarke D

更新日期：2003-01-01 00:00:00

abstract：:Gene conversion is defined as the non-reciprocal transfer of information between homologous sequences. Despite methodological problems to establish non-reciprocity, gene conversion has been demonstrated in a wide variety of bacteria. Besides examples of high-frequency reversion of mutations in repeated genes, gene con...

journal_title：FEMS microbiology reviews

authors： Santoyo G,Romero D

更新日期：2005-04-01 00:00:00

abstract：:Stress responses are crucial for bacteria to survive harmful conditions that they encounter in the environment. Although gene regulatory mechanisms underlying stress responses in bacteria have been thoroughly characterised for decades, recent advances in imaging technologies helped to uncover previously hidden dynamic...

journal_title：FEMS microbiology reviews

authors： Lagage V,Uphoff S

更新日期：2020-09-01 00:00:00

abstract：:Dengue is the most prevalent arthropod-borne viral disease, caused by dengue virus, a member of the Flaviviridae family. Its worldwide incidence is now a major health problem, with 2.5 billion people living in risk areas. In this review, we integrate the structural rearrangements of each viral protein and their functi...

journal_title：FEMS microbiology reviews

authors： Cruz-Oliveira C,Freire JM,Conceição TM,Higa LM,Castanho MA,Da Poian AT

更新日期：2015-03-01 00:00:00

abstract：:Cyanobacteria of the genera Synechococcus and Prochlorococcus dominate the prokaryotic component of the picophytoplankton in the oceans. It is still less than 10 years since the discovery of phages that infect marine Synechococcus and the beginning of the characterisation of these phages and assessment of their ecolog...

journal_title：FEMS microbiology reviews

authors： Mann NH

更新日期：2003-04-01 00:00:00

abstract：:Fungal mycelial by-products from fermentation industries present a considerable affinity for soluble metal ions (e.g. Zn, Cd, Ni, Pb, Cr, Ag) and could be used in biosorption processes for purification of contaminated effluents. In this work the influence of pH on sorption parameters is characterized by measuring the ...

journal_title：FEMS microbiology reviews

authors： Fourest E,Canal C,Roux JC

更新日期：1994-08-01 00:00:00

abstract：:The yeast Saccharomyces cerevisiae has been a favorite organism for pioneering studies on nutrient-sensing and signaling mechanisms. Many specific nutrient responses have been elucidated in great detail. This has led to important new concepts and insight into nutrient-controlled cellular regulation. Major highlights i...

journal_title：FEMS microbiology reviews

authors： Conrad M,Schothorst J,Kankipati HN,Van Zeebroeck G,Rubio-Texeira M,Thevelein JM

更新日期：2014-03-01 00:00:00

abstract：:Wall teichoic acids (WTAs) are charged glycopolymers containing phosphodiester-linked polyol units and represent one of the major components of Gram-positive cell envelope. WTAs have important physiological functions in cell division, gene transfer, surface adhesion, drug resistance, and biofilm formation, and are cri...

journal_title：FEMS microbiology reviews

authors： Wu X,Han J,Gong G,Koffas MAG,Zha J

更新日期：2020-12-03 00:00:00

abstract：:In recent years, there has been accumulating evidence that antibiotics, besides their antimicrobial action, potentially have a number of undesired side effects that can, at least in some cases, promote genetic variability of bacteria. In addition to resistant variants, antibiotics have also been shown to select mutato...

journal_title：FEMS microbiology reviews

authors： Couce A,Blázquez J

更新日期：2009-05-01 00:00:00

abstract：:Bacteria of the genus Brucella are Gram-negative pathogens of several animal species that cause a zoonotic disease in humans known as brucellosis or Malta fever. Within their hosts, brucellae reside within different cell types where they establish a replicative niche and remain protected from the immune response. The ...

journal_title：FEMS microbiology reviews

authors： von Bargen K,Gorvel JP,Salcedo SP

更新日期：2012-05-01 00:00:00

abstract：:In the last decade, a variety of ribosomally synthesized antimicrobial peptides or bacteriocins produced by lactic acid bacteria have been identified and characterized. As a result of these studies, insight has been gained into fundamental aspects of biology and biochemistry such as producer self protection, membrane-...

journal_title：FEMS microbiology reviews

authors： Ennahar S,Sashihara T,Sonomoto K,Ishizaki A

更新日期：2000-01-01 00:00:00