Metabolic adaptation of human pathogenic and related nonpathogenic bacteria to extra- and intracellular habitats.

abstract：:The urogenital tract appears to be the only niche of the human body that shows clear differences in microbiota between men and women. The female reproductive tract has special features in terms of immunological organization, an epithelial barrier, microbiota, and influence by sex hormones such as estrogen. While the u...

journal_title：FEMS microbiology reviews

authors： Petrova MI,van den Broek M,Balzarini J,Vanderleyden J,Lebeer S

更新日期：2013-09-01 00:00:00

abstract：:A high frequency of human cytomegalovirus (HCMV) genome and antigens in tumor samples of patients with different malignancies is now well documented, although the causative role for HCMV in the development of the neoplasias remains to be established. HCMV infection can modulate multiple cellular regulatory and signall...

journal_title：FEMS microbiology reviews

authors： Cinatl J Jr,Vogel JU,Kotchetkov R,Wilhelm Doerr H

更新日期：2004-02-01 00:00:00

abstract：:In the present review, we aim to provide a general introduction to different facets of the arms race between pathogens and their hosts/environment, emphasizing its evolutionary aspects. We focus on vector-borne parasitic protozoa, which have to adapt to both invertebrate and vertebrate hosts. Using Leishmania, Trypano...

journal_title：FEMS microbiology reviews

authors： Caljon G,De Muylder G,Durnez L,Jennes W,Vanaerschot M,Dujardin JC

更新日期：2016-09-01 00:00:00

abstract：:Targeted manipulation of the gut flora is increasingly being recognized as a means to improve human health. Yet, the temporal dynamics and intra- and interindividual heterogeneity of the microbiome represent experimental limitations, especially in human cross-sectional studies. Therefore, rodent models represent an in...

journal_title：FEMS microbiology reviews

authors： Laukens D,Brinkman BM,Raes J,De Vos M,Vandenabeele P

更新日期：2016-01-01 00:00:00

abstract：:In this paper, it is suggested that specificity and non-specificity in (oral) microbial adhesion are different expressions for the same phenomena. It is argued that the same basic, physicochemical forces are responsible for so-called 'non-specific' and 'specific' binding and that from a physico-chemical point of view ...

journal_title：FEMS microbiology reviews

authors： Busscher HJ,Cowan MM,van der Mei HC

更新日期：1992-06-01 00:00:00

abstract：:Human protein kinase C (PKC) isoforms have been implicated in diseases such as Alzheimer's, diabetes and cancers. In contrast to mammals, which have at least nine genes, fungi have only one or two. The yeast Saccharomyces cerevisiae produces only a single Pkc1 and is employed in the study of specific human isozymes, i...

journal_title：FEMS microbiology reviews

authors： Heinisch JJ,Rodicio R

更新日期：2018-01-01 00:00:00

abstract：:Small cells dominate photosynthetic biomass and primary production in many marine ecosystems. Traditionally, picoplankton refers to cells < or =2 microm. Here we extend the size range of the organisms considered to 3 microm, a threshold often used operationally in field studies. While the prokaryotic component of pico...

journal_title：FEMS microbiology reviews

authors： Vaulot D,Eikrem W,Viprey M,Moreau H

更新日期：2008-08-01 00:00:00

abstract：:The gram-negative bacterium Proteus mirabilis can exist in either of two cell types, a vegetative cell characterized as a short rod and a highly elongated and hyperflagellated swarmer cell. This differentiation is triggered by growth on solid surfaces and multiple inputs are sensed by the cell to initiate the differen...

journal_title：FEMS microbiology reviews

authors： Morgenstein RM,Szostek B,Rather PN

更新日期：2010-09-01 00:00:00

abstract：:Nickel is an essential nutrient for selected microorganisms where it participates in a variety of cellular processes. Many microbes are capable of sensing cellular nickel ion concentrations and taking up this nutrient via nickel-specific permeases or ATP-binding cassette-type transport systems. The metal ion is specif...

journal_title：FEMS microbiology reviews

authors： Mulrooney SB,Hausinger RP

更新日期：2003-06-01 00:00:00

abstract：:Gene regB of bacteriophage T4 encodes a sequence-specific endoribonuclease which introduces cuts in early phage messenger RNAs. In most cases, cutting takes place in the middle of the tetranucleotide GGAG. Efficient cleavages occur in the motifs located in intergenic regions, some of them being Shine-Dalgarno sequence...

journal_title：FEMS microbiology reviews

authors： Sanson B,Uzan M

更新日期：1995-08-01 00:00:00

abstract：:The accurate synthesis of proteins, dictated by the corresponding nucleotide sequence encoded in mRNA, is essential for cell growth and survival. Central to this process are the aminoacyl-tRNA synthetases (aaRSs), which provide amino acid substrates for the growing polypeptide chain in the form of aminoacyl-tRNAs. The...

journal_title：FEMS microbiology reviews

authors： Hausmann CD,Ibba M

更新日期：2008-07-01 00:00:00

abstract：:The wealth of information existing on the general principle of S-layers has revealed a broad application potential. The most relevant features exploited in applied S-layer research are: (i) pores passing through S-layers show identical size and morphology and are in the range of ultrafiltration membranes; (ii) functio...

journal_title：FEMS microbiology reviews

authors： Sleytr UB,Bayley H,Sára M,Breitwieser A,Küpcü S,Mader C,Weigert S,Unger FM,Messner P,Jahn-Schmid B,Schuster B,Pum D,Douglas K,Clark NA,Moore JT,Winningham TA,Levy S,Frithsen I,Pankovc J,Beale P,Gillis HP,Choutov

更新日期：1997-06-01 00:00:00

abstract：:Arsenic compounds have been abundant at near toxic levels in the environment since the origin of life. In response, microbes have evolved mechanisms for arsenic resistance and enzymes that oxidize As(III) to As(V) or reduce As(V) to As(III). Formation and degradation of organoarsenicals, for example methylarsenic comp...

journal_title：FEMS microbiology reviews

authors： Mukhopadhyay R,Rosen BP,Phung LT,Silver S

更新日期：2002-08-01 00:00:00

abstract：:The genome of bacteriophage fd has been engineered to allow foreign amino acid sequences to be displayed in the exposed N-terminal segment of the major coat protein in the virus particle: small peptides can be encoded directly; larger peptides are encoded in hybrid virions, in which wild-type coat protein subunits are...

journal_title：FEMS microbiology reviews

authors： Perham RN,Terry TD,Willis AE,Greenwood J,di Marzo Veronese F,Appella E

更新日期：1995-08-01 00:00:00

abstract：:The production of the fusion protein staphylococcal protein A/E. coli beta-galactosidase in Escherichia coli was studied in batch and fed batch cultivations. Batch cultivation of a recombinant E. coli strain yielded a final cell dry weight of 16.4 g l-1 with a final intracellular product concentration of recombinant p...

journal_title：FEMS microbiology reviews

authors： Strandberg L,Andersson L,Enfors SO

更新日期：1994-05-01 00:00:00

abstract：:Human enteric pathogenic viruses can enter the environment through discharge of waste materials from infected persons, and be transmitted back to susceptible persons to continue the cycle of disease. Contamination of food with viruses may also promote disease outbreaks. A number of studies have investigated the surviv...

journal_title：FEMS microbiology reviews

authors： Rzezutka A,Cook N

更新日期：2004-10-01 00:00:00

abstract：:Protists include all eukaryotes except plants, fungi and animals. They are an essential, yet often forgotten, component of the soil microbiome. Method developments have now furthered our understanding of the real taxonomic and functional diversity of soil protists. They occupy key roles in microbial foodwebs as consum...

journal_title：FEMS microbiology reviews

authors： Geisen S,Mitchell EAD,Adl S,Bonkowski M,Dunthorn M,Ekelund F,Fernández LD,Jousset A,Krashevska V,Singer D,Spiegel FW,Walochnik J,Lara E

更新日期：2018-05-01 00:00:00

abstract：:Research innovations are constantly occurring in universities, research institutions and industrial research laboratories. These are reported in the scientific literature and presented to the scientific community in various congresses and symposia as well as through direct contacts and collaborations. Conversion of th...

journal_title：FEMS microbiology reviews

authors： Pedersen MB,Iversen SL,Sørensen KI,Johansen E

更新日期：2005-08-01 00:00:00

abstract：:DNA microarrays are a powerful and promising approach to gain a detailed understanding of the bacterial response and the molecular cross-talk that can occur as a consequence of host-pathogen interactions. However, published studies mainly describe the host response to infection. Analysis of bacterial gene regulation i...

journal_title：FEMS microbiology reviews

authors： La MV,Raoult D,Renesto P

更新日期：2008-05-01 00:00:00

abstract：:Five species of parasite cause malaria in humans with the most severe disease caused by Plasmodium falciparum. Many of the proteins encoded in the P. falciparum genome are unusually enriched in repetitive low-complexity sequences containing a limited repertoire of amino acids. These repetitive sequences expand and con...

journal_title：FEMS microbiology reviews

authors： Davies HM,Nofal SD,McLaughlin EJ,Osborne AR

更新日期：2017-11-01 00:00:00

abstract：:A number of peptidases and proteases have been identified in Escherichia coli. Although their specific physiological roles are often not known, some of them have been shown to be involved in: the maturation of nascent polypeptide chains; the maturation of protein precursors; the signal peptide processing of exported p...

journal_title：FEMS microbiology reviews

authors： Lazdunski AM

更新日期：1989-09-01 00:00:00

abstract：:Bacteria of the genus Brucella are Gram-negative pathogens of several animal species that cause a zoonotic disease in humans known as brucellosis or Malta fever. Within their hosts, brucellae reside within different cell types where they establish a replicative niche and remain protected from the immune response. The ...

journal_title：FEMS microbiology reviews

authors： von Bargen K,Gorvel JP,Salcedo SP

更新日期：2012-05-01 00:00:00

abstract：:The herbivore rumen ecosystem constitutes an extremely efficient degradation machinery for the intricate chemical structure of fiber biomass, thus, enabling the hosting animal to digest its feed. The challenging task of deconstructing and metabolizing fiber is performed by microorganisms inhabiting the rumen. Since mo...

journal_title：FEMS microbiology reviews

authors： Moraïs S,Mizrahi I

更新日期：2019-07-01 00:00:00

abstract：:Invasive bacterial pathogens intervene at various stages and by various mechanisms with the mammalian plasminogen/plasmin system. A vast number of pathogens express plasmin(ogen) receptors that immobilize plasmin(ogen) on the bacterial surface, an event that enhances activation of plasminogen by mammalian plasminogen ...

journal_title：FEMS microbiology reviews

authors： Lähteenmäki K,Kuusela P,Korhonen TK

更新日期：2001-12-01 00:00:00

abstract：:Antibiotic resistance mechanisms reported in Gram-negative bacteria are causing a worldwide health problem. The continuous dissemination of 'multidrug-resistant' (MDR) bacteria drastically reduces the efficacy of our antibiotic 'arsenal' and consequently increases the frequency of therapeutic failure. In MDR bacteria,...

journal_title：FEMS microbiology reviews

authors： Nikaido H,Pagès JM

更新日期：2012-03-01 00:00:00

abstract：:Understanding the structure, functionalities and biology of functional amyloids is an issue of emerging interest. Inclusion bodies, namely protein clusters formed in recombinant bacteria during protein production processes, have emerged as unanticipated, highly tunable models for the scrutiny of the physiology and arc...

journal_title：FEMS microbiology reviews

authors： de Marco A,Ferrer-Miralles N,Garcia-Fruitós E,Mitraki A,Peternel S,Rinas U,Trujillo-Roldán MA,Valdez-Cruz NA,Vázquez E,Villaverde A

更新日期：2019-01-01 00:00:00

abstract：:Heat-shock proteins (hsps) have been identified as molecular chaperones conserved between microbes and man and grouped by their molecular mass and high degree of amino acid homology. This article reviews the major hsps of Saccharomyces cerevisiae, their interactions with trehalose, the effect of fermentation and the r...

journal_title：FEMS microbiology reviews

authors： Burnie JP,Carter TL,Hodgetts SJ,Matthews RC

更新日期：2006-01-01 00:00:00

abstract：:What a living organism looks like and how it works and what are its components-all this is encoded on DNA, the genetic blueprint. Consequently, the way to change an organism is to change its genetic information. Since the first pieces of recombinant DNA have been used to transform cells in the 1970s, this approach has...

journal_title：FEMS microbiology reviews

authors： Schindler D,Waldminghaus T

更新日期：2015-11-01 00:00:00

abstract：:Wall teichoic acids (WTAs) are charged glycopolymers containing phosphodiester-linked polyol units and represent one of the major components of Gram-positive cell envelope. WTAs have important physiological functions in cell division, gene transfer, surface adhesion, drug resistance, and biofilm formation, and are cri...

journal_title：FEMS microbiology reviews

authors： Wu X,Han J,Gong G,Koffas MAG,Zha J

更新日期：2020-12-03 00:00:00

abstract：:Magnetotactic bacteria (MB) are remarkable organisms with the ability to exploit the earth's magnetic field for navigational purposes. To do this, they build specialized compartments called magnetosomes that consist of a lipid membrane and a crystalline magnetic mineral. These organisms have the potential to serve as ...

journal_title：FEMS microbiology reviews

authors： Komeili A

更新日期：2012-01-01 00:00:00