Abstract:
:The accurate synthesis of proteins, dictated by the corresponding nucleotide sequence encoded in mRNA, is essential for cell growth and survival. Central to this process are the aminoacyl-tRNA synthetases (aaRSs), which provide amino acid substrates for the growing polypeptide chain in the form of aminoacyl-tRNAs. The aaRSs are essential for coupling the correct amino acid and tRNA molecules, but are also known to associate in higher order complexes with proteins involved in processes beyond translation. Multiprotein complexes containing aaRSs are found in all three domains of life playing roles in splicing, apoptosis, viral assembly, and regulation of transcription and translation. An overview of the complexes aaRSs form in all domains of life is presented, demonstrating the extensive network of connections between the translational machinery and cellular components involved in a myriad of essential processes beyond protein synthesis.
journal_name
FEMS Microbiol Revjournal_title
FEMS microbiology reviewsauthors
Hausmann CD,Ibba Mdoi
10.1111/j.1574-6976.2008.00119.xsubject
Has Abstractpub_date
2008-07-01 00:00:00pages
705-21issue
4eissn
0168-6445issn
1574-6976pii
FMR119journal_volume
32pub_type
杂志文章,评审abstract::The genus Corynebacterium belongs to the taxonomic class Actinobacteria representing the high G+C branch of gram-positive bacteria. Among the most prominent members of this genus is Corynebacterium glutamicum, which is used by the biotechnological industry for the fermentative production of l-amino acids. Because of i...
journal_title:FEMS microbiology reviews
pub_type: 杂志文章,评审
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abstract::Heat-shock proteins (hsps) have been identified as molecular chaperones conserved between microbes and man and grouped by their molecular mass and high degree of amino acid homology. This article reviews the major hsps of Saccharomyces cerevisiae, their interactions with trehalose, the effect of fermentation and the r...
journal_title:FEMS microbiology reviews
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journal_title:FEMS microbiology reviews
pub_type: 杂志文章,评审
doi:10.1111/1574-6976.12029
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journal_title:FEMS microbiology reviews
pub_type: 杂志文章,评审
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abstract::Type II (proteic) toxin-antitoxin (TA) operons are widely spread in bacteria and archaea. They are organized as operons in which, usually, the antitoxin gene precedes the cognate toxin gene. The antitoxin generally acts as a transcriptional self-repressor, whereas the toxin acts as a co-repressor, both proteins consti...
journal_title:FEMS microbiology reviews
pub_type: 杂志文章,评审
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journal_title:FEMS microbiology reviews
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journal_title:FEMS microbiology reviews
pub_type: 杂志文章,评审
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journal_title:FEMS microbiology reviews
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journal_title:FEMS microbiology reviews
pub_type: 杂志文章,评审
doi:10.1111/1574-6976.12015
更新日期:2013-05-01 00:00:00
abstract::Phenotypically heterogeneous microenvironments emerge as biofilms mature across different environments. Phenotypic heterogeneity in biofilm sub-populations not obeying quorum sensing-dictated, collective group behavior may be considered as a strategy allowing non-conformists to survive hostile conditions. Heterogeneou...
journal_title:FEMS microbiology reviews
pub_type: 杂志文章,评审
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更新日期:2018-05-01 00:00:00
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journal_title:FEMS microbiology reviews
pub_type: 杂志文章,评审
doi:10.1093/femsre/fuz007
更新日期:2019-07-01 00:00:00
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journal_title:FEMS microbiology reviews
pub_type: 杂志文章,评审
doi:10.1093/femsre/fuv024
更新日期:2015-09-01 00:00:00
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journal_title:FEMS microbiology reviews
pub_type: 杂志文章,评审
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更新日期:2003-10-01 00:00:00
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journal_title:FEMS microbiology reviews
pub_type: 杂志文章,评审
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更新日期:2009-05-01 00:00:00
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journal_title:FEMS microbiology reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1574-6976.2011.00301.x
更新日期:2012-03-01 00:00:00
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journal_title:FEMS microbiology reviews
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更新日期:2000-12-01 00:00:00
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更新日期:2012-03-01 00:00:00
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journal_title:FEMS microbiology reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1574-6976.2010.00229.x
更新日期:2010-09-01 00:00:00
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journal_title:FEMS microbiology reviews
pub_type: 杂志文章,评审
doi:10.1093/femsre/fux027
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abstract::Pathogenicity and symbiosis are central to bacteria-host interactions. Although several human pathogens have been subjected to functional genomic analysis, we still understand little about bacteria-invertebrate interactions despite their ecological prevalence. Advances in our knowledge of this area are often hindered ...
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pub_type: 杂志文章,评审
doi:10.1111/j.1574-6976.2003.tb00625.x
更新日期:2003-01-01 00:00:00
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journal_title:FEMS microbiology reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1574-6976.2001.tb00590.x
更新日期:2001-12-01 00:00:00
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journal_title:FEMS microbiology reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1574-6976.2006.00049.x
更新日期:2007-01-01 00:00:00
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journal_title:FEMS microbiology reviews
pub_type: 杂志文章,评审
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更新日期:1997-08-01 00:00:00
abstract::The head assembly pathway of bacteriophage HK97 shares many features with head assembly pathways determined for other dsDNA phages, and it also provides examples of novel variations on the basic theme. We describe aspects of two specific steps in the assembly pathway, the covalent cross-linking among the assembled hea...
journal_title:FEMS microbiology reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1574-6976.1995.tb00186.x
更新日期:1995-08-01 00:00:00
abstract::We review and update the work on genetic elements, e.g., viruses and plasmids (exluding IS elements and transposons) in the kingdom Crenarchaeota (Thermoproteales and Sulfolobales) and the orders Thermococcales and Thermoplasmales in the kingdom Euryarchaeota of the archael domain, including unpublished data from our ...
journal_title:FEMS microbiology reviews
pub_type: 杂志文章,评审
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更新日期:1996-05-01 00:00:00