Abstract:
:Bovine cell lines individually expressing two related herpesviral proteins, pseudorabies virus glycoprotein 50 and herpes simplex virus type 1 glycoprotein D, were examined for their susceptibility/resistance to infection with several alphaherpesviruses. Cell lines expressing gp50 or gD-1 resisted plaque formation by the homologous virus more than by the heterologous viruses. Bovine cells expressing bovine herpesvirus 1 glycoprotein IV (gIV) were susceptible to infection with three other bovine herpesviruses: bovine herpesvirus 2, bovine herpesvirus 4 (BHV-4) and alcelaphine herpesvirus 1. One line of gIV-expressing cells was resistant to the formation of BHV-4 plaques, suggesting that a cell-associated factor may be responsible for inhibiting cell-to-cell spread.
journal_name
Virologyjournal_title
Virologyauthors
Chase CC,Lohff C,Letchworth GJ 3rddoi
10.1006/viro.1993.1269subject
Has Abstractpub_date
1993-05-01 00:00:00pages
365-9issue
1eissn
0042-6822issn
1096-0341pii
S0042-6822(83)71269-9journal_volume
194pub_type
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