West Nile virus infection of Drosophila melanogaster induces a protective RNAi response.

abstract：:The Autographa californica multiple nucleopolyhedrovirus (AcMNPV) occlusion-derived virus (ODV) envelope protein ODV-E56 is essential for oral infection of larvae of Heliothis virescens. Bioassays with recombinant clones of AcMNPV lacking a functional odv-e56 gene showed that ODV-E56 was required for infectivity of bo...

journal_title：Virology

authors： Sparks WO,Harrison RL,Bonning BC

更新日期：2011-01-05 00:00:00

abstract：:Several strains of tobacco ringspot virus (TobRV) support the replication and encapsidation of satellite tobacco ringspot virus RNA (STobRV RNA). We have compared the nucleotide sequences of four STobRV RNAs, each initially associated with a different isolate of TobRV. A STobRV RNA from a geranium isolate of TobRV and...

journal_title：Virology

authors： Buzayan JM,McNinch JS,Schneider IR,Bruening G

更新日期：1987-09-01 00:00:00

abstract：:The natural host of SIVrcm is the red-capped mangabey (Cercocebus torquatus torquatus). Although this virus infects macaques and human PBMCs, its pathogenic potential is unknown. We serially passaged SIVrcm through 9 rhesus macaques to assess its potential for virulence. SIVrcm infected all macaques with peak viremia ...

journal_title：Virology

authors： Ling B,Veazey RS,Marx PA

更新日期：2008-09-15 00:00:00

abstract：:The synthesis of linear duplex replicative structures (monomers, head-to-head, and tail-to-tail dimers) is an important hallmark of the productive phase of the adeno-associated virus (AAV) life cycle. These structures are generated by a strand-displacement replication mechanism and believed to be a reservoir for singl...

journal_title：Virology

authors： Musatov SA,Scully TA,Dudus L,Fisher KJ

更新日期：2000-09-30 00:00:00

abstract：:An in-frame gag gene mutant of human immunodeficiency virus type 1, which carries two amino acid substitutions in the center of the p24 coding region, was constructed in vitro, and its replication properties in several cell lines were examined. In CD4-negative SW480 cells transfected with the mutant clone, synthesis a...

journal_title：Virology

authors： Sakuragi J,Sakai H,Kawamura M,Tokunaga K,Ueda S,Adachi A

更新日期：1995-09-10 00:00:00

abstract：:The behavior of two genetically different molecular clones of visna virus KV1772-kv72/67 and LV1-1KS1 was compared in vivo and in vitro. On intracerebral inoculation, clone KV1772-kv72/67 induced a similar response in five sheep as has already been reported with neurovirulent derivates of visna virus. Virus was freque...

journal_title：Virology

authors： Torsteinsdóttir S,Agnarsdóttir G,Matthíasdóttir S,Rafnar B,Andrésdóttir V,Andrésson OS,Staskus K,Pétursson G,Pálsson PA,Georgsson G

更新日期：1997-03-17 00:00:00

abstract：:Dengue virus (DENV) is an arbovirus that belongs to the Flaviviridae family. Studies reveal that peptides secreted by amphibians have many functions, such as antiviral and antimicrobial activities. As there is no antiviral drug effective against the DENV, the antiviral activity of a synthetic peptide called HS-1, deri...

journal_title：Virology

authors： Monteiro JMC,Oliveira MD,Dias RS,Nacif-Marçal L,Feio RN,Ferreira SO,Oliveira LL,Silva CC,Paula SO

更新日期：2018-01-15 00:00:00

abstract：:The causal agent of rhizomania disease, Beet necrotic yellow vein virus (BNYVV), typically produces asymptomatic root-limited infections in sugar beets (Beta vulgaris) carrying the Rz1-allele. Unfortunately, this dominant resistance has been recently overcome. Multiple cDNA clones of the viral pathogenic determinant p...

journal_title：Virology

authors： Acosta-Leal R,Fawley MW,Rush CM

更新日期：2008-06-20 00:00:00

abstract：:Seven envelope regions from two series of patient isolates have been molecularly cloned and analyzed for replication phenotypes and immunogenicity. Growth potential was analyzed for env sequences substituted into an HIV-1-NL4-3 backbone (NL4-3/env recombinants). Immunogenicity studies were conducted on secreted monome...

journal_title：Virology

authors： Mustafa F,Richmond JF,Fernandez-Larsson R,Lu S,Fredriksson R,Fenyö EM,O'Connell M,Johnson E,Weng J,Santoro JC,Robinson HL

更新日期：1997-03-03 00:00:00

abstract：:Six deletion mutations and an insertion were generated in the env gene of cloned copies of Moloney murine leukemia virus DNA. All seven mutants were replication-defective as tested by transformation of NIH/3T3 cells. The mutant DNAs were introduced into NIH/3T3 cells to generate stable producer lines; all released vir...

journal_title：Virology

authors： Granowitz C,Colicelli J,Goff SP

更新日期：1991-08-01 00:00:00

abstract：:Cell lines persistently infected with foot-and-mouth disease virus (FMDV) have been established by growth of BHK-21 (c-13) or IBRS-2 (c-26) that survived standard cytolytic infections with FMDV. They maintain cytoplasmic FMDV RNA sequences, as shown by dot blot hybridization tests, using cloned FMDV cDNA as probes. Ce...

journal_title：Virology

authors： de la Torre JC,Dávila M,Sobrino F,Ortín J,Domingo E

更新日期：1985-08-01 00:00:00

abstract：:Previous studies indicated that hepatitis C virus core protein influences cellular apoptosis. However, the precise mechanisms of the effects are not fully understood. Therefore, in this study, we examined the mechanisms of the effects on cell apoptosis by core protein, using transiently transfected and magnetically co...

journal_title：Virology

authors： Otsuka M,Kato N,Taniguchi H,Yoshida H,Goto T,Shiratori Y,Omata M

更新日期：2002-04-25 00:00:00

abstract：:Epstein-Barr virus nuclear antigen 1 (EBNA 1) has been shown to be a sequence-specific DNA binding protein that is required for the replication of episomal elements carrying the viral origin of DNA replication, oriP, as well as for the activation of a specific transcriptional enhancer. We have constructed and analyzed...

journal_title：Virology

authors： Polvino-Bodnar M,Schaffer PA

更新日期：1992-04-01 00:00:00

abstract：:Very fast sedimenting DNA (VFS DNA) of T4 phage, which is formed by infection with a mutant in gene 49, was examined by electron microscopy after mild treatment with DNase I. It showed Y-shaped, branched strands in addition to linear strands. Each branch contained a single-stranded interruption about 60 nucleotides lo...

journal_title：Virology

authors： Minagawa T,Murakami A,Ryo Y,Yamagishi H

更新日期：1983-04-15 00:00:00

abstract：:It is well established that the human subgroup C adenovirus type 5 (Ad5) E1B 55 kDa protein can regulate the activity and concentration of the cellular tumor suppressor, p53. However, the contribution(s) of these functions of the E1B protein to viral reproduction remains unclear. To investigate this issue, we examined...

journal_title：Virology

authors： Cardoso FM,Kato SE,Huang W,Flint SJ,Gonzalez RA

更新日期：2008-09-01 00:00:00

abstract：:Poliovirus readily establishes a persistent infection in the K562-Mu erythroleukemia cell strain. In this study, three additional K562 cell strains were analyzed for their responses to poliovirus infection and found to be quite variable. K562 cells obtained from the ATCC established a persistent infection, similar to ...

journal_title：Virology

authors： Benton PA,Murphy JW,Lloyd RE

更新日期：1995-10-20 00:00:00

abstract：:The function of a substantial percentage of the putative protein-coding open reading frames (ORFs) in viral genomes is unknown. As their sequence is not similar to that of proteins of known function, the function of these ORFs cannot be assigned on the basis of sequence similarity. Methods complement or in combination...

journal_title：Virology

authors： Han LY,Cai CZ,Ji ZL,Chen YZ

更新日期：2005-01-05 00:00:00

abstract：:Feline foamy virus (FeFV) belongs to the group of spumaretroviruses that contain in addition to gag, pol, and env accessory genes collectively called bel genes. Primate FVs have been shown to utilize internal promoters in addition to the 5' LTR promoters. In contrast to other known retroviruses, the FV pol genes are e...

journal_title：Virology

authors： Bodem J,Löchelt M,Delius H,Flügel RM

更新日期：1998-05-10 00:00:00

abstract：:The budded phenotype of Autograha californica nuclear polyhedrosis virus (AcNPV BV) has a 64K glycoprotein in its envelope which is important in the ability of the virus to functionally enter host cells. Tunicamycin (TM), an inhibitor of N-linked glycosylation, was used to determine whether the sugar moiety was essent...

journal_title：Virology

authors： Charlton CA,Volkman LE

更新日期：1986-10-15 00:00:00

abstract：:The incidence of head and neck squamous cell carcinomas (HNSCCs) is rising in developed countries. This is driven by an increase in HNSCCs caused by high-risk human papillomavirus (HPV) infections or HPV + HNSCCs. Compared to HNSCCs not caused by HPV (HPV- HNSCCs), HPV + HNSCCs are more responsive to therapy and assoc...

journal_title：Virology

authors： Holcomb AJ,Brown L,Tawfik O,Madan R,Shnayder Y,Thomas SM,Wallace NA

更新日期：2020-09-01 00:00:00

abstract：:Many tumors, including cervical carcinoma, show dysregulated expression of the microRNA processing machinery, specifically DROSHA and DICER. Some cervical cancers exhibit chromosome 5p amplifications and DROSHA is the most significantly upregulated transcript and is observed in all tumors with 5p gain. DROSHA and DICE...

journal_title：Virology

authors： Harden ME,Munger K

更新日期：2017-07-01 00:00:00

abstract：:The 2009 influenza pandemic originated from a swine-origin H1N1 virus, which, although less pathogenic than anticipated, may acquire additional virulence-associated mutations in the future. To estimate the potential risk, we sequentially passaged the isolate A/Hamburg/04/2009 in A549 human lung epithelial cells. After...

journal_title：Virology

authors： Wörmann X,Lesch M,Welke RW,Okonechnikov K,Abdurishid M,Sieben C,Geissner A,Brinkmann V,Kastner M,Karner A,Zhu R,Hinterdorfer P,Anish C,Seeberger PH,Herrmann A,Meyer TF,Karlas A

更新日期：2016-05-01 00:00:00

abstract：:Classical swine fever virus (CSFV) is a positive-sense RNA virus with a high degree of genetic variability among isolates. High diversity is also found in virulence, with strains covering the complete spectrum from avirulent to highly virulent. The underlying genetic determinants are far from being understood. Since R...

journal_title：Virology

authors： Töpfer A,Höper D,Blome S,Beer M,Beerenwinkel N,Ruggli N,Leifer I

更新日期：2013-03-30 00:00:00

abstract：:In order to study the effect of nef gene expression on viral replication in monocytic cells, we established monocytic (U937 and THP-1) cell transfectants constitutively expressing the human immunodeficiency virus type 1 nef gene. We constructed a plasmid expressing the nef gene derived from an infectious clone, NL432,...

journal_title：Virology

authors： Tsunetsugu-Yokota Y,Matsuda S,Maekawa M,Saito T,Takemori T,Takebe Y

更新日期：1992-12-01 00:00:00

abstract：:A full-length cDNA of cucurbit aphid-borne yellows virus (CABYV) has been constructed and expressed either as an in vitro transcript, under control of a bacteriophage T7 RNA polymerase promoter, or in vivo, under control of the cauliflower mosaic virus 35S promoter in an agroinfection vector. The biological activity o...

journal_title：Virology

authors： Prüfer D,Wipf-Scheibel C,Richards K,Guilley H,Lecoq H,Jonard G

更新日期：1995-12-01 00:00:00

abstract：:The efficacy of combining immunization with human immunodeficiency vitus type 1 (HIV-1) DNA and HIV-1 recombinant proteins to obtain protection from chimeric simian/human immunodeficiency virus (SHIV) was determined. Four cynomolgus monkeys received four gene-gun immunizations intraepidermally of plasmid DNA encoding ...

journal_title：Virology

authors： Putkonen P,Quesada-Rolander M,Leandersson AC,Schwartz S,Thorstensson R,Okuda K,Wahren B,Hinkula J

更新日期：1998-10-25 00:00:00

abstract：:Autographa californica multiple nucleopolyhedrovirus (AcMNPV) ac92 is a core gene encoding a protein associated with occlusion derived virus (ODV), binds human P53 and also has flavin adenine dinucleotide linked sulfhydryl oxidase activity but its role in the virus life cycle is not known. To determine ac92 function a...

journal_title：Virology

authors： Nie Y,Fang M,Theilmann DA

更新日期：2011-01-05 00:00:00

abstract：:G1/S transition of the cell cycle is blocked when cells are cultured without cell adhesion, even if nutrients and serum are present. Shift experiments involving transfer from adhesion to suspension cultures have revealed that cell adhesion in the early half of G1 phase is required for induction of DNA synthesis. We fo...

journal_title：Virology

authors： Inoue H,Yamashita A,Hakura A

更新日期：1996-11-01 00:00:00

abstract：:There is growing evidence that the receptor-binding characteristics of influenza viruses are affected by the host-dependent glycosylation of viral hemagglutinin (HA). To better understand these effects, we propagated two variants of the human influenza virus USSR/90/77 (which differed by the mutation Asn131 reversible...

journal_title：Virology

authors： Gambaryan AS,Marinina VP,Tuzikov AB,Bovin NV,Rudneva IA,Sinitsyn BV,Shilov AA,Matrosovich MN

更新日期：1998-08-01 00:00:00

abstract：:The human cytomegalovirus (HCMV) US12 gene family is a group of 10 predicted seven-transmembrane domain proteins that have some features in common with G-protein-coupled receptors. Little is known of their patterns of expression, localization, or functional interactions. Here, we studied the intracellular localization...

journal_title：Virology

authors： Das S,Pellett PE

更新日期：2007-05-10 00:00:00