Changes in the intraisolate genetic structure of Beet necrotic yellow vein virus populations associated with plant resistance breakdown.

abstract：:Resistance to lethal encephalitis in mice infected with HSV-1 via the oral mucosa is mouse strain dependent. In susceptible BALB/c, HSV-1 spreads throughout the CNS but in resistant BL/6 mice, virus is restricted to the brainstem. To examine the contribution of cellular immunity in restricting viral spread, we used a ...

journal_title：Virology

authors： Kastrukoff LF,Lau AS,Takei F,Smyth MJ,Jones CM,Clarke SR,Carbone FR

更新日期：2010-05-10 00:00:00

abstract：:The primary cell types that sustain polyomavirus (Py) replication following intranasal infection as well as the nature of the host cellular response to Py were unknown. As this is an essential and specific site for virus entry, it seems likely that viral gene function must be adapted to these mucosal tissues. Using im...

journal_title：Virology

authors： Gottlieb K,Villarreal LP

更新日期：2000-01-05 00:00:00

abstract：:Small non-coding microRNAs (miRNAs) can modulate the outcome of virus infection. Here we explore the role of miRNAs in insect-virus interactions, in vivo, using the natural Drosophila melanogaster-Drosophila C virus (DCV) model system. Comparison of the miRNA expression profiles in DCV-infected and uninfected flies sh...

journal_title：Virology

authors： Monsanto-Hearne V,Tham ALY,Wong ZS,Asgari S,Johnson KN

更新日期：2017-02-01 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) Rev is a 19-kDa regulatory protein which binds to unspliced and partially spliced HIV-1 RNAs. Export, splicing, stability, and translation of HIV-1 RNAs are influenced by Rev. To further understand the effect of Rev on HIV-1 RNA splicing, the intranuclear localization of uns...

journal_title：Virology

authors： Favaro JP,Borg KT,Arrigo SJ,Schmidt MG

更新日期：1998-09-30 00:00:00

abstract：:The regions of the AcMNPV genome represented as cytoplasmic transcripts early after infection of Spodoptera frugiperda cells prior to and encompassing the initiation of DNA replication were mapped. In vivo(32)P pulse-labeled cytoplasmic RNA from infected cells at various times postinfection was used to probe Southern ...

journal_title：Virology

authors： Erlandson MA,Carstens EB

更新日期：1983-04-15 00:00:00

abstract：:Infection of lymphocytes by the Epstein-Barr virus (EBV) is initiated by attachment of the major virus glycoprotein gp350/220 to a cell surface glycoprotein, known as CR2 (CD21). In a productive infection the virus envelope fuses with host cell membranes either at the cell surface or within endocytic vesicles. To inve...

journal_title：Virology

authors： Patel RA,Hutt-Fletcher LM,Crews FT

更新日期：1993-07-01 00:00:00

abstract：:We measured the effects of non-nucleoside reverse transcriptase (RT) inhibitor-resistant mutations K101E+G190S, on replication fitness and EFV-resistance of HIV(NL4-3). K101E+G190S reduced fitness in the absence of EFV and increased EFV resistance, compared to either single mutant. Unexpectedly, K101E+G190S also repli...

journal_title：Virology

authors： Wang J,Liang H,Bacheler L,Wu H,Deriziotis K,Demeter LM,Dykes C

更新日期：2010-07-05 00:00:00

abstract：:The CD4+ T-cell-restricted recognition of the structural proteins in the JHM strain of MHV (JHMV) was compared between two mouse strains. Following immunization with inactivated JHMV, all proteins elicited an immune response in both C57BL/6 and BALB/c mouse strains, except the nucleocapsid (N) protein, which was not i...

journal_title：Virology

authors： van der Veen RC

更新日期：1996-11-15 00:00:00

abstract：:Adenovirus serotype 5 (Ad5) is a common cause of respiratory tract infection, and populations worldwide have high prevalence of anti-Ad5 antibodies, implying extensively prior infection. Ad5 infection potently activates the host innate defense and inflammation, but the molecular mechanisms are not completely clarified...

journal_title：Virology

authors： Li P,Feng F,Pan E,Fan X,Yang Q,Guan M,Chen L,Sun C

更新日期：2018-06-01 00:00:00

abstract：:The porcine lymphotropic herpesvirus 1 (PLHV-1), the first gammaherpesvirus of pigs, has been detected at a high prevalence in healthy pig populations. A porcine gammaherpesvirus has also been detected at high copy numbers in animals suffering from posttransplant lymphoproliferative disease (PTLD). While human PTLD is...

journal_title：Virology

authors： Goltz M,Ericsson T,Patience C,Huang CA,Noack S,Sachs DH,Ehlers B

更新日期：2002-03-15 00:00:00

abstract：:The DNA sequence of bovine herpesvirus type 1 (BHV-1) ST strain (BHV-1.2 subtype) entire unique short (US) region and part of adjacent flanking sequences of the inverted repeats was determined. The BHV-1 ST US region is 9745 bp in size and has a 70.5% G + C content. Eight potential open reading frames (ORFs) longer th...

journal_title：Virology

authors： Leung-Tack P,Audonnet JC,Riviere M

更新日期：1994-03-01 00:00:00

abstract：:The splice acceptor site of pX gene of HTLV-I has been determined to be at base position 7301 using S1 nuclease protection analysis. This splice acceptor site is used in all HTLV-I immortalized T-cell clones studied despite variation in the abundance levels of pX mRNA. Our results confirmed the proposal by Haseltine e...

journal_title：Virology

authors： Okamoto T,Josephs SF,Kawanishi M,Wong-Staal F

更新日期：1985-06-01 00:00:00

abstract：:The circular single-stranded viral DNA (ssDNA) of filamentous phage is oriented in the virus with a hairpin forming sequence called mos at the leading end of the virion-the end that emerges from the cell first. In the experiments that originally defined mos it was also found to enhance virion production 100-fold, thou...

journal_title：Virology

authors： Bauer M,Smith GP

更新日期：1988-11-01 00:00:00

abstract：:Avipoxviruses are significant pathogens infecting a wide range of wild and domestic bird species globally. Here, we describe a novel genome sequence of magpiepox virus (MPPV) isolated from an Australian magpie. In the present study, histopathologically confirmed cutaneous pox lesions were used for transmission electro...

journal_title：Virology

authors： Sarker S,Batinovic S,Talukder S,Das S,Park F,Petrovski S,Forwood JK,Helbig KJ,Raidal SR

更新日期：2020-01-15 00:00:00

abstract：:Sequence analysis of the murine gamma-herpesvirus 68 (gammaHV68) genome previously identified several open reading frames (ORFs) located at the left end of the viral genome that do not share homology with other known herpesvirus or cellular genes. Here, we show that one of these ORFs, M4, encodes a secreted glycoprote...

journal_title：Virology

authors： Evans AG,Moorman NJ,Willer DO,Speck SH

更新日期：2006-01-20 00:00:00

abstract：:The V3 loop of HIV-1 gp120 is considered occluded on many primary viruses. However, virus sensitivity to neutralization by different V3 mAbs often varies, indicating that access to V3 is not restricted equally for all antibodies. Here, we have sought to gain a better understanding of these restrictions by determining ...

journal_title：Virology

authors： Pantophlet R,Wrin T,Cavacini LA,Robinson JE,Burton DR

更新日期：2008-11-25 00:00:00

abstract：:Binding of simian virus 40 (SV40) large T antigen to human and calf thymus topoisomerase I (topo I) was readily detected by using modified enzyme-linked immunosorbent assays and immunoblots. In addition to WT T antigen, binding could also be readily demonstrated with T antigen fragments from the amino-terminal region ...

journal_title：Virology

authors： Simmons DT,Melendy T,Usher D,Stillman B

更新日期：1996-08-15 00:00:00

abstract：:NF-kappaB comprises a family of transcription factors that regulate key immune processes. In this study, the effects of orthopoxvirus infection upon the activation of NF-kappaB were examined. During the early phase of infection, cowpox virus can inhibit the induction of NF-kappaB-regulated gene expression by interferi...

journal_title：Virology

authors： Oie KL,Pickup DJ

更新日期：2001-09-15 00:00:00

abstract：:Packaging of lambda DNA is mediated by the phage-encoded enzyme, terminase, which acts at a site termed cos. cos consists of cosB, the site where terminase binds lambda DNA, and cosN, the site where nicks are introduced to generate the cohesive ends of virion DNA. cos contains multiple binding sites for gpNu1, the sma...

journal_title：Virology

authors： Yeo A,Kosturka LD,Feiss M

更新日期：1990-01-01 00:00:00

abstract：:We reported earlier that variable expression of the Epstein-Barr virus (EBV) encoded membrane protein LMP 1 in nasopharyngeal carcinoma and the host-cell-phenotype-dependent activity of the BCR2 promoter (one of the possible initiator sites for transcripts of Epstein-Barr nuclear antigens) in Burkitt's lymphoma (BL) l...

journal_title：Virology

authors： Minarovits J,Hu LF,Minarovits-Kormuta S,Klein G,Ernberg I

更新日期：1994-05-01 00:00:00

abstract：:In addition to the major ectodomain, the gp41 transmembrane glycoprotein of HIV-1 is now known to have a minor ectodomain that is part of the long C-terminal tail. Both ectodomains are highly antigenic, carry neutralizing and non-neutralizing epitopes, and are involved in virus-mediated fusion activity. However, data ...

journal_title：Virology

authors： Hollier MJ,Dimmock NJ

更新日期：2005-07-05 00:00:00

abstract：:Arabis mosaic virus is a subgroup A nepovirus. The RNA1-encoded polyprotein (P1) contains the domains for the NTP-binding protein (NTB), VPg, proteinase (Pro) and polymerase at its C-terminus. Putative cleavage sites delineating these domains have been proposed. However, the number and location of cleavage sites upstr...

journal_title：Virology

authors： Wetzel T,Chisholm J,Bassler A,Sanfaçon H

更新日期：2008-05-25 00:00:00

abstract：:We established the transcription map of early region (E) 3 of bovine adenovirus 3 (BAV-3) by Northern blot, S1 nuclease protection assays, cDNA sequencing, and RT-PCR analysis. Five major classes of mRNAs were identified, which shared the 3' ends. Four classes of mRNAs transcribed from the E3 promoter also shared the ...

journal_title：Virology

authors： Idamakanti N,Reddy PS,Babiuk LA,Tikoo SK

更新日期：1999-04-10 00:00:00

abstract：:We examined the molecular epidemiology and evolution of Ross River (RR) virus in Australia and the Pacific Islands. Nucleotide sequences of the E2 and E3 genes of five RR virus strains revealed remarkable conservation between 1959 and 1989 with a maximum divergence of only 3.3%. Sequence data from a 505-base pair frag...

journal_title：Virology

authors： Sammels LM,Coelen RJ,Lindsay MD,Mackenzie JS

更新日期：1995-09-10 00:00:00

abstract：:The flavivirus nonstructural protein NS1 has been implicated in viral RNA replication, although its precise role has not been identified. In its native state NS1 exists as a heat labile homodimer that is thought to be required for NS1 function and secretion. However, we have recently identified a cDNA clone of KUN vir...

journal_title：Virology

authors： Hall RA,Khromykh AA,Mackenzie JM,Scherret JH,Khromykh TI,Mackenzie JS

更新日期：1999-11-10 00:00:00

abstract：:The host-virus interaction during the cellular entry of Japanese encephalitis virus (JEV) is poorly characterized. The ubiquitin-proteasome system (UPS), the major intracellular proteolytic pathway, mediates diverse cellular processes, including endocytosis and signal transduction, which may be involved in the entry o...

journal_title：Virology

authors： Wang S,Liu H,Zu X,Liu Y,Chen L,Zhu X,Zhang L,Zhou Z,Xiao G,Wang W

更新日期：2016-11-01 00:00:00

abstract：:The molecular mechanism(s) by which human immunodeficiency virus (HIV-1) injures a T-cell line was studied. A pathological role for viral env proteins, which are inserted into the plasma membrane, has been previously demonstrated for HIV as well as other retroviruses which are cytopathic. We therefore initiated studie...

journal_title：Virology

authors： Lynn WS,Tweedale A,Cloyd MW

更新日期：1988-03-01 00:00:00

abstract：:Corn lethal necrosis (CLN) is caused by the synergistic interaction between maize chlorotic mottle machlomovirus (MCMV) and any potyvirus which infects cereals. Interactions between MCMV and wheat streak mosaic rymovirus (WSMV) in N28Ht corn produced MCMV concentrations that averaged 3.3- to 11.2-fold higher in doubly...

journal_title：Virology

authors： Scheets K

更新日期：1998-03-01 00:00:00

abstract：:Following mechanical inoculation of leaves with turnip yellow mosaic virus (TYMV), a significant proportion of the retained inoculum is uncoated within 45 sec, and the process is more or less complete after 2 min. At least 80-90% of the uncoating takes place in the epidermis. The application of virus to the intact lea...

journal_title：Virology

authors： Matthews RE,Witz J

更新日期：1985-07-30 00:00:00

abstract：:Two major infectious forms of vaccinia virus (VACV) have been described: the intracellular mature virion (IMV), and the extracellular enveloped virion (EEV). Due to their stability in the environment, IMVs play a predominant role in host-to-host transmission, whereas EEVs play an important role in dissemination within...

journal_title：Virology

authors： Hooper JW,Custer DM,Thompson E

更新日期：2003-02-01 00:00:00