Complete genome analysis and molecular characterization of Usutu virus that emerged in Austria in 2001: comparison with the South African strain SAAR-1776 and other flaviviruses.

abstract：:We have validated a flexible, high-throughput and relatively inexpensive RT-QPCR array platform for absolute quantification of Epstein-Barr virus transcripts in different latent and lytic infection states. Several novel observations are reported. First, during infection of normal B cells, Wp-initiated latent gene tran...

journal_title：Virology

authors： Tierney RJ,Shannon-Lowe CD,Fitzsimmons L,Bell AI,Rowe M

更新日期：2015-01-01 00:00:00

abstract：:The majority of HIV-1 infections occur via sexual intercourse. Women are the most affected by the epidemic, particularly in developing countries, due to their socio-economic dependence on men and the fact that they are often victims of gender based sexual violence. Despite significant efforts that resulted in the redu...

journal_title：Virology

authors： Alexandre KB,Mufhandu HT,London GM,Chakauya E,Khati M

更新日期：2016-10-01 00:00:00

abstract：:A new set of lambdoid phages (mEp) classified into different immunity groups was previously described. Phages mEp213, mEp237, and mEp410 were unable to grow in mEp167 lysogenic cells, presumably due to an exclusion mechanism expressed constitutively by the mEp167 repressed prophage. In this work, to analyze the exclus...

journal_title：Virology

authors： Uc-Mass A,Loeza EJ,de la Garza M,Guarneros G,Hernández-Sánchez J,Kameyama L

更新日期：2004-11-24 00:00:00

abstract：:A crucial step in the arenavirus life cycle is the proteolytic processing of the viral envelope glycoprotein precursor (GPC) by the cellular proprotein convertase (PC) subtilisin kexin isozyme-1 (SKI-1)/site-1 protease (S1P). Here we conducted a systematic and quantitative analysis of SKI-1/S1P processing of peptides ...

journal_title：Virology

authors： Pasquato A,Burri DJ,Traba EG,Hanna-El-Daher L,Seidah NG,Kunz S

更新日期：2011-08-15 00:00:00

abstract：:cDNA clones encoding the envelope glycoprotein E1 of rubella virus (RV) were altered by site-directed mutagenesis at consensus sites for addition of N-linked glycans. The resulting plasmids were introduced into COS cells and the mutant E1 proteins were analyzed by indirect immunofluorescence, radioimmunoprecipitation,...

journal_title：Virology

authors： Hobman TC,Qiu ZY,Chaye H,Gillam S

更新日期：1991-04-01 00:00:00

abstract：:The complete nucleotide sequence of the nucleocapsid (N) gene of lettuce necrotic yellows virus (LNYV), the type member of the genus Cytorhabdovirus of plant rhabdoviruses, has been determined from cDNA clones of both the viral genomic and messenger RNAs. The previously identified N gene was adjacent to the 3' leader ...

journal_title：Virology

authors： Wetzel T,Dietzgen RG,Geering AD,Dale JL

更新日期：1994-08-01 00:00:00

abstract：:When hemagglutinin (HA) and neuraminidase (NA) are presented together on an intact influenza virus particle, the antigens are competitive, with HA dominant over NA in T- and B-cell priming. Immunization with mixtures of purified HA and NA eliminates antigenic competition between HA and NA, as well as between N1-N2 NA ...

journal_title：Virology

authors： Johansson BE,Kilbourne ED

更新日期：1996-11-01 00:00:00

abstract：:Section of the sciatic nerve during the period of herpes simplex virus (HSV) latent infection was performed to evaluate residual latency in mouse dorsal root ganglion. In control mice without sciatic neurectomy, latency was present in 90-100%, while in those which underwent a neurectomy procedure, latent infection was...

journal_title：Virology

authors： Tenser RB,Edris WA,Hay KA

更新日期：1988-11-01 00:00:00

abstract：:An Ad2 capsid component, the penton base, expressed as recombinant protein, was found to be capable of affecting the entire entry pathway of adenovirion in HeLa cells, i.e., cell attachment, endocytosis, vesicular escape, intracytoplasmic movement, and translocation through the nuclear pore complex. Data with pentamer...

journal_title：Virology

authors： Hong SS,Gay B,Karayan L,Dabauvalle MC,Boulanger P

更新日期：1999-09-15 00:00:00

abstract：:Three different protein molecules copurify with T4 tail tubes after the tubes are released from the baseplate by guanidine hydrochloride treatment. These tube-associated proteins (TAPs) are the products of genes 29, 48, and 54. To further investigate the structural roles that these proteins may play in T4 tail assembl...

journal_title：Virology

authors： Ishimoto LK,Ishimoto KS,Cascino A,Cipollaro M,Eiserling FA

更新日期：1988-05-01 00:00:00

abstract：:Infection of human helper T lymphocytes with the human immunodeficiency virus (HIV) results in a rapid induction of cytopathic effects and cell lysis. We isolated a variant of the human T-lymphoblastoid cell line, CEM, that is fully susceptible to HIV infection but resistant to virally induced cytopathic effects. Expo...

journal_title：Virology

authors： Casareale D,Stevenson M,Sakai K,Volsky DJ

更新日期：1987-01-01 00:00:00

abstract：:Immunization with heat-inactivated herpes simplex virus type 1 (HSV-1) 2-5 days before ocular infection reduced the frequency of establishment of latent HSV-1 infection in the trigeminal ganglion (TG); this induction of resistance coincided with reduced expression of IFN-gamma mRNA in the TG. Immunization with unrelat...

journal_title：Virology

authors： Halford WP,Veress LA,Gebhardt BM,Carr DJ

更新日期：1997-09-29 00:00:00

abstract：:The sequence of the 1491 nucleotides found at the 3' end of the genome of the highly aphid-transmissible (HAT) isolate of tobacco etch virus (TEV) has been determined. The nucleotide sequence of the capsid protein gene has been identified and compared with the corresponding region of the not-aphid-transmissible (NAT) ...

journal_title：Virology

authors： Allison RF,Dougherty WG,Parks TD,Willis L,Johnston RE,Kelly M,Armstrong FB

更新日期：1985-12-01 00:00:00

abstract：:Three full-length genomic clones (pB19-M20, pB19-FL and pB19-HG1) of parvovirus B19 were produced in different laboratories. pB19-M20 was shown to produce infectious virus. To determine the differences in infectivity, all three plasmids were tested by transfection and infection assays. All three clones were similar in...

journal_title：Virology

authors： Filippone C,Zhi N,Wong S,Lu J,Kajigaya S,Gallinella G,Kakkola L,Söderlund-Venermo M,Young NS,Brown KE

更新日期：2008-05-10 00:00:00

abstract：:We previously demonstrated that human parainfluenza virus type 2 (hPIV-2) induces RhoA activation, which promotes its growth. RhoA controls the equilibrium between globular and filamentous actin (F-actin). We found that F-actin formation is induced by wild type (wt) hPIV-2 infection, and that inhibition of F-actin for...

journal_title：Virology

authors： Ohta K,Matsumoto Y,Yumine N,Nishio M

更新日期：2018-11-01 00:00:00

abstract：:In this article we report the initial biochemical, genetic, and electron microscopic analysis of a previously uncharacterized, 8.9-kDa, predicted thiol-redox protein. The name A2.5L was assigned to the corresponding vaccinia virus gene, which is conserved in all sequenced poxviruses. Multiple alignment analysis and se...

journal_title：Virology

authors： Senkevich TG,White CL,Weisberg A,Granek JA,Wolffe EJ,Koonin EV,Moss B

更新日期：2002-09-01 00:00:00

abstract：:Hypervariable region 1 (HVR1) proteins of hepatitis C virus (HCV) have been reported to react broadly with sera of patients with HCV infection. However, the variability of the broad reactivity of individual HVR1 proteins has not been elucidated. We assessed the reactivity of 25 different HVR1 proteins (genotype 1b) wi...

journal_title：Virology

authors： Watanabe K,Yoshioka K,Ito H,Ishigami M,Takagi K,Utsunomiya S,Kobayashi M,Kishimoto H,Yano M,Kakumu S

更新日期：1999-11-10 00:00:00

abstract：:The cowpea strain of Southern bean mosaic virus (SBMV-C), a T = 3 icosahedral RNA virus, was dissociated to yield a ribonucleoprotein complex (RNPC) composed of the viral RNA and coat protein subunits. To determine if the coat protein subunits were bound to a specific site on the viral RNA, the RNPC was treated with r...

journal_title：Virology

authors： Hacker DL

更新日期：1995-03-10 00:00:00

abstract：:Alpacas develop diminished disease following bovine viral diarrhea virus (BVDV) infection compared to cattle. We hypothesized that alpaca and bovine cells have differential permissiveness and responses to BVDV infection. To characterize alpaca testicular (AT) and bovine turbinate (BT) cells BVDV infection permissivene...

journal_title：Virology

authors： Samson HC,Topliff CL,Donis RO,Kelling CL

更新日期：2011-04-25 00:00:00

abstract：:Computational analysis of human adenovirus type 4 (HAdV-E4), a pathogen that is the only HAdV member of species E, provides insights into its zoonotic origin and molecular adaptation. Its genome encodes a domain of the major capsid protein, hexon, from HAdV-B16 recombined into the genome chassis of a simian adenovirus...

journal_title：Virology

authors： Dehghan S,Seto J,Liu EB,Walsh MP,Dyer DW,Chodosh J,Seto D

更新日期：2013-09-01 00:00:00

abstract：:The reticuloendotheliosis virus (REV) group of retroviruses and type D simian retroviruses (SRV) belong to the same receptor interference group. The cellular receptor for these viruses has not yet been identified. In order to study the distribution of the receptor and to identify a receptor negative cell line, vector ...

journal_title：Virology

authors： Koo HM,Parthasarathi S,Ron Y,Dougherty JP

更新日期：1994-11-15 00:00:00

abstract：:The CD4+ T-cell-restricted recognition of the structural proteins in the JHM strain of MHV (JHMV) was compared between two mouse strains. Following immunization with inactivated JHMV, all proteins elicited an immune response in both C57BL/6 and BALB/c mouse strains, except the nucleocapsid (N) protein, which was not i...

journal_title：Virology

authors： van der Veen RC

更新日期：1996-11-15 00:00:00

abstract：:The differential symptom determinants of the Holmes' masked (M) and U1 strains of tobacco mosaic virus previously were mapped to the 5'-coterminal open reading frame (ORF) encoding the 126-kDa protein and the N-terminal two-thirds of the 183-kDa protein. Both proteins influence viral RNA accumulation, but the function...

journal_title：Virology

authors： Shintaku MH,Carter SA,Bao Y,Nelson RS

更新日期：1996-07-01 00:00:00

abstract：:Previous studies indicated that hepatitis C virus core protein influences cellular apoptosis. However, the precise mechanisms of the effects are not fully understood. Therefore, in this study, we examined the mechanisms of the effects on cell apoptosis by core protein, using transiently transfected and magnetically co...

journal_title：Virology

authors： Otsuka M,Kato N,Taniguchi H,Yoshida H,Goto T,Shiratori Y,Omata M

更新日期：2002-04-25 00:00:00

abstract：:Nucleos(t)ide analogues that inhibit hepatitis B virus (HBV) DNA replication are typically used as monotherapy for chronically infected patients. Treatment with a nucleos(t)ide analogue eliminates most HBV DNA replication intermediates and produces a gradual decline in levels of covalently closed circular DNA (cccDNA)...

journal_title：Virology

authors： Reaiche-Miller GY,Thorpe M,Low HC,Qiao Q,Scougall CA,Mason WS,Litwin S,Jilbert AR

更新日期：2013-11-01 00:00:00

abstract：:We test the hypothesis that the translation machinery in cells infected by influenza A virus efficiently translates only mRNAs that possess the influenza viral 5' untranslated region (5'-UTR) by introducing mRNAs directly into the cytoplasm of infected cells. This strategy avoids effects due to the inhibition of the n...

journal_title：Virology

authors： Cassetti MC,Noah DL,Montelione GT,Krug RM

更新日期：2001-10-25 00:00:00

abstract：:HIV-1 Vpu antagonizes the block to particle release mediated by CD317 (BST-2/HM1.24/Tetherin) via incompletely understood mechanisms. Vpu and CD317 partially reside in cholesterol-rich lipid rafts where HIV-1 budding preferentially occurs. Here we find that lipid raft association of ectopically expressed or endogenous...

journal_title：Virology

authors： Fritz JV,Tibroni N,Keppler OT,Fackler OT

更新日期：2012-03-01 00:00:00

abstract：:We examined the assembly processes of the capsid proteins of canine parvovirus (CPV) in mammalian and insect cells. In CPV-infected cells empty capsids assembled within 15 min, and then continued to form over the following 1 h, while full (DNA-containing) capsids were detected only after 60 min, and those accumulated ...

journal_title：Virology

authors： Yuan W,Parrish CR

更新日期：2001-01-20 00:00:00

abstract：:Marek's disease virus (MDV) is a representative alpha herpes virus able to induce rapid-onset T-cell lymphoma in its natural host and regarded as an ideal model for the study of virus-induced tumorigenesis. Recent studies have shown that the mdv1-miR-M4-5p, a viral analog of cellular miR-155, is critical for MDV׳s onc...

journal_title：Virology

authors： Chi JQ,Teng M,Yu ZH,Xu H,Su JW,Zhao P,Xing GX,Liang HD,Deng RG,Qu LH,Zhang GP,Luo J

更新日期：2015-02-01 00:00:00

abstract：:The glycoprotein E (gE) of varicella zoster virus (VZV), encoded by ORF68, is the most abundant viral glycoprotein. In the current experiments, we demonstrated that ORF68 deletion was incompatible with recovery of infectious virus from VZV cosmids. Replacing ORF68 at a nonnative AvrII site in the genome restored infec...

journal_title：Virology

authors： Mo C,Lee J,Sommer M,Grose C,Arvin AM

更新日期：2002-12-20 00:00:00