Circovirus in domestic and wild carnivores: An important opportunistic agent?

Abstract:

:Circoviruses are relatively novel pathogens with increased importance in canids. In this study, we first screened the presence of dog circovirus (DogCV) by molecular methods from a total number of 389 internal organ samples originating from 277 individuals of domestic dogs and wild animals including wolves, foxes and badgers. All the animals originated from Central-Southern Italy, specifically from Abruzzi and Molise regions, areas hosting several natural parks. DogCV was detected in 9/34 wolves (P=26.4%; IC 95%: 14.6-43.1%), 8/209 dogs (P=3.8%; IC 95%: 1.9-7.3%), 0/24 foxes (P=0%; IC 95%: 0-13.8%), 1/10 badgers (P=10%; IC 95%: 1.79-40.4%). However, all DogCV positive animals were shown to be infected at least by an additional key pathogen, including canine distemper virus (CDV) and canine parvovirus type 2. All wolves, but one, presenting DogCV in the internal tissues suffered from CDV infection. The DNA purified from 17 DogCV infected organs was used for whole genome sequencing and phylogenetic analysis.

journal_name

Virology

journal_title

Virology

authors

Zaccaria G,Malatesta D,Scipioni G,Di Felice E,Campolo M,Casaccia C,Savini G,Di Sabatino D,Lorusso A

doi

10.1016/j.virol.2016.01.007

subject

Has Abstract

pub_date

2016-03-01 00:00:00

pages

69-74

eissn

0042-6822

issn

1096-0341

pii

S0042-6822(16)00010-6

journal_volume

490

pub_type

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