Reduced levels of alpha1(XI) procollagen mRNA in SV40-transformed cells.

abstract：:Marek' disease virus serotype-1, also know as Gallid herpesvirus 2 (GaHV-2), elicits T-cell lymphomas in chickens. The GaHV-2 genome encodes an oncoprotein, Meq, with similarity to the Jun/Fos family of proteins. We have previously shown that Meq homodimers are not sufficient to induce lymphomas in chickens. In this s...

journal_title：Virology

authors： Suchodolski PF,Izumiya Y,Lupiani B,Ajithdoss DK,Lee LF,Kung HJ,Reddy SM

更新日期：2010-04-10 00:00:00

abstract：:We have previously described a revertant cell line which expresses a dominant tumor suppressor phenotype to E1 but not to heterologous oncogenes such as c-myc, N-ras, or polyoma middle t (Sircar et al. (1988) Oncogene 3, 725-728). DNA tumor virus oncogenes have been suggested to transform cells via the common mechanis...

journal_title：Virology

authors： Sircar S,Horvath J,Roberge D,Diouri M,Weber JM

更新日期：1992-11-01 00:00:00

abstract：:SIV/Mne circle junctions were amplified by the polymerase chain reaction (PCR) and cloned in a bacterial plasmid. Sequence analysis of clones isolated from 11 independent PCRs reveals that the start site for plus DNA synthesis is 5' ACTG. . ., and thus an asymmetric cleavage must occur during viral integration. In add...

journal_title：Virology

authors： Randolph CA,Champoux JJ

更新日期：1993-06-01 00:00:00

abstract：:The sequences of the 3'-noncoding regions (NCR) of 12 strains of tick-borne encephalitis (TBE) virus were analyzed and found to vary in length from 350 to approximately 750 nucleotides. The size heterogeneity is restricted to a variable region following the stop codon, whereas the most 3'-terminal 350 nucleotides form...

journal_title：Virology

authors： Wallner G,Mandl CW,Kunz C,Heinz FX

更新日期：1995-10-20 00:00:00

abstract：:The preS(21-47) sequence of the hepatitis B virus (HBV) envelope protein is involved in binding of the virus to cell receptors. A protein similarity search revealed a partial homology between this sequence and a segment of the human immunoglobulin A (IgA) heavy chain constant region, suggesting that the cell attachmen...

journal_title：Virology

authors： Neurath AR,Strick N

更新日期：1990-10-01 00:00:00

abstract：:The Epstein-Barr virus (EBV) BGLF4 gene product is the only protein kinase encoded by the virus genome. In order to elucidate its physiological roles in viral productive replication, we here established a BGLF4-knockout mutant and a revertant virus. While the levels of viral DNA replication of the deficient mutant wer...

journal_title：Virology

authors： Murata T,Isomura H,Yamashita Y,Toyama S,Sato Y,Nakayama S,Kudoh A,Iwahori S,Kanda T,Tsurumi T

更新日期：2009-06-20 00:00:00

abstract：:The group B noncultivatable rotavirus, ADRV, was purified from infected stool specimens. Double-stranded RNA was extracted, polyadenylated, reverse transcribed into cDNA, and cloned into plasmid vector pAT153. Each cDNA clone hybridized to a single ADRV RNA segment and cDNA clones of each genomic RNA segment were iden...

journal_title：Virology

authors： Chen GM,Hung T,Mackow ER

更新日期：1990-04-01 00:00:00

abstract：:We have investigated the role of vif in maedi-visna virus (MVV), a lentivirus of sheep, by studying in vitro replication of vif-deleted MVV in several cell types, and the effects of vif deletion on in vivo infection. By measuring RT activity, we found that in comparison to wild-type MVV, growth of vif-deleted MVV was ...

journal_title：Virology

authors： Kristbjörnsdóttir HB,Andrésdóttir V,Svansson V,Torsteinsdóttir S,Matthíasdóttir S,Andrésson OS

更新日期：2004-01-05 00:00:00

abstract：:The tail sheath protein of giant bacteriophage phiKZ Pseudomonas aeruginosa encoded by gene 29 was identified and its expression system was developed. Localization of the protein on the virion was confirmed by immunoelectron microscopy. Properties of gene product (gp) 29 were studied by electron microscopy, immunoblot...

journal_title：Virology

authors： Kurochkina LP,Aksyuk AA,Sachkova MY,Sykilinda NN,Mesyanzhinov VV

更新日期：2009-12-20 00:00:00

abstract：:Without a virus culture system, genetic analysis becomes the principal method to classify norovirus (NoV) strains. Currently, classification of NoV strains beneath the species level has been based on sequences from different regions of the viral genome. As a result, the phylogenetic insights of some virus were not app...

journal_title：Virology

authors： Zheng DP,Ando T,Fankhauser RL,Beard RS,Glass RI,Monroe SS

更新日期：2006-03-15 00:00:00

abstract：:West Nile virus (WNV) is a flavivirus that swept rapidly across North America in 1999, declined in prevalence, and then resurged in 2012. To date, no vaccine is available to prevent infection in the human population. Herpes simplex virus (HSV) replication-defective vaccine vectors induce a durable immunity characteriz...

journal_title：Virology

authors： Taylor TJ,Diaz F,Colgrove RC,Bernard KA,DeLuca NA,Whelan SPJ,Knipe DM

更新日期：2016-09-01 00:00:00

abstract：:We recently reported the phenomenon of retroviral insertion into a herpesvirus (Isfort et al., (1992) Proc. Natl. Acad. Sci. USA 89, 991-995). We have now isolated Marek's disease virus (MDV) clones that carry retroviral inserts. Retroviral LTR insertion has the potential to activate or inactivate herpesvirus genes le...

journal_title：Virology

authors： Kost R,Jones D,Isfort R,Witter R,Kung HJ

更新日期：1993-01-01 00:00:00

abstract：:To investigate the mode of gene expression of red clover mottle virus (RCMV) middle component (M) RNA, we have synthesized an oligopeptide corresponding to the predicted carboxy-terminus of the RCMV counterparts of the cowpea mosaic virus (CPMV) 48K and 58K proteins. Using an antiserum raised against this synthetic ol...

journal_title：Virology

authors： Shanks M,Tomenius K,Clapham D,Huskisson NS,Barker PJ,Wilson IG,Maule AJ,Lomonossoff GP

更新日期：1989-12-01 00:00:00

abstract：:Tissues from Australian brushtail possums (Trichosurus vulpecula) that had been experimentally infected with wobbly possum disease (WPD) virus (WPDV) were examined to elucidate pathogenesis of WPDV infection. Mononuclear inflammatory cell infiltrates were present in livers, kidneys, salivary glands and brains of WPD-a...

journal_title：Virology

authors： Giles J,Perrott M,Roe W,Shrestha K,Aberdein D,Morel P,Dunowska M

更新日期：2018-09-01 00:00:00

abstract：:We investigated the localization of host mRNA during Rift Valley fever virus (RVFV) infection. Fluorescence in situ hybridization revealed that infection with RVFV altered the localization of host mRNA. mRNA accumulated in the nuclei of RVFV-infected but not mock-infected cells. Further, overexpression of the NSS gene...

journal_title：Virology

authors： Copeland AM,Van Deusen NM,Schmaljohn CS

更新日期：2015-12-01 00:00:00

abstract：:Hepatitis C virus (HCV) was shown to activate protein kinase R (PKR), which inhibits expression of interferon (IFN) and IFN-stimulated genes by controlling the translation of newly transcribed mRNAs. However, it is unknown exactly how HCV activates PKR. To address the molecular mechanism(s) of PKR activation mediated ...

journal_title：Virology

authors： Suzuki R,Matsuda M,Shimoike T,Watashi K,Aizaki H,Kato T,Suzuki T,Muramatsu M,Wakita T

更新日期：2019-03-01 00:00:00

abstract：:The transcripts of the DNA of Abutilon mosaic virus, a geminivirus with a bipartite genome (DNA A and DNA B), were characterized by Northern blot hybridization, S1 nuclease assay, primer extension analysis, and sequencing of the 3' termini of cDNA clones. It was shown that transcription is bidirectional and that the t...

journal_title：Virology

authors： Frischmuth S,Frischmuth T,Jeske H

更新日期：1991-12-01 00:00:00

abstract：:Purification of the putative cowpea mosaic virus (CPMV) RNA replicase previously started with an RNA-dependent RNA polymerase activity which had been solubilized from a crude membrane fraction of CPMV-infected cowpea leaves by extraction with a Mg2+-deficient buffer. This led to the identification of a host-encoded, 1...

journal_title：Virology

authors： Dorssers L,van der Meer J,Van Kammen A,Zabel P

更新日期：1983-02-01 00:00:00

abstract：:Respiratory syncytial virus is a major cause of bronchiolitis in infants and pneumonia virus of mice (PVM) causes similar disease in mice. The impact of PVM infection in BALB/c and C57BL/6 neonates, and upon re-infection as elderly mice, was compared. As previously shown for adult mice, PVM caused more disease in BALB...

journal_title：Virology

authors： Shrivastava P,Atanley E,Sarkar I,Watkiss E,Gomis S,van Drunen Littel-van den Hurk S

更新日期：2015-11-01 00:00:00

abstract：:Hepatitis C virus (HCV) core protein constitutes a viral nucleocapsid and may possess multiple functions. In this study, we demonstrated the homotypic interaction and multimerization of HCV core protein in vitro and in vivo. By using a yeast two-hybrid system, we showed that the amino-terminal hydrophilic portion (ami...

journal_title：Virology

authors： Matsumoto M,Hwang SB,Jeng KS,Zhu N,Lai MM

更新日期：1996-04-01 00:00:00

abstract：:Ten human genital invasive squamous cell carcinomas and five human premalignant tissues were analyzed for the presence of selected sets of herpes simplex virus 2 (HSV-2) DNA sequences. Two vulvar tumors and one vulvar dysplastic tissue were found to contain DNA sequences homologous to the BglII O fragment (coordinates...

journal_title：Virology

authors： Manservigi R,Cassai E,Deiss LP,Di Luca D,Segala V,Frenkel N

更新日期：1986-11-01 00:00:00

abstract：:The 380-kb chlorella virus NY-2A genome is highly methylated; 45% of the cytosines are 5-methylcytosine (5mC) and 37% of the adenines are N6-methyladenine (6mA). Based on the sensitivity/resistance of NY-2A DNA to 80 methylation-sensitive DNA restriction endonucleases, the virus is predicted to encode at least 10 DNA ...

journal_title：Virology

authors： Zhang Y,Nelson M,Nietfeldt J,Xia Y,Burbank D,Ropp S,Van Etten JL

更新日期：1998-01-20 00:00:00

abstract：:Oral transmission of human immunodeficiency virus (HIV) in adult populations is rare. However, HIV spread across fetal/neonatal oropharyngeal epithelia could be important in mother-to-child transmission. Analysis of HIV transmission across polarized adult and fetal oral epithelial cells revealed that HIV transmigrates...

journal_title：Virology

authors： Tugizov SM,Herrera R,Veluppillai P,Greenspan D,Soros V,Greene WC,Levy JA,Palefsky JM

更新日期：2011-01-20 00:00:00

abstract：:Infection of different human epithelial cell lines with human respiratory syncytial virus (HRSV) revealed significant differences in the electrophoretic mobility of the viral attachment glycoprotein (G). Cell-type specific differences in G protein glycosylation were observed with certain lectins and sugar-specific rea...

journal_title：Virology

authors： García-Beato R,Martínez I,Francí C,Real FX,García-Barreno B,Melero JA

更新日期：1996-07-15 00:00:00

abstract：:Recently, we identified TT virus (TTV) isolates from nonhuman primates and named them simian TTV (s-TTV). To characterize the genomic structure of these isolates in more detail, the full-length nucleotide sequence of the s-TTV isolate (designated s-TTV CH65-1), recovered from a chimpanzee born in West Africa, was ampl...

journal_title：Virology

authors： Inami T,Obara T,Moriyama M,Arakawa Y,Abe K

更新日期：2000-11-25 00:00:00

abstract：:The bipartite genomic RNAs of red clover necrotic mosaic virus (RCNMV) lack a 5' cap and a 3' poly(A) tail. RNA1 encodes viral replication proteins, and RNA2 encodes a movement protein (MP). These proteins are translated in a cap-independent manner. We previously identified two cis-acting RNA elements that cooperative...

journal_title：Virology

authors： Tajima Y,Iwakawa HO,Hyodo K,Kaido M,Mise K,Okuno T

更新日期：2017-09-01 00:00:00

abstract：:Human cytomegalovirus U(L)112-113 encodes four phosphoproteins, pp84, pp50, pp43, and pp34, with common amino-termini. A previous report by Kerry et al. (J. Virol. 70, 373-382, 1996) demonstrated that U(L)112-113 products activate U(L)54 promoter in cooperation with immediate-early (IE) proteins. In this study, we ide...

journal_title：Virology

authors： Li J,Yamamoto T,Ohtsubo K,Shirakata M,Hirai K

更新日期：1999-07-20 00:00:00

abstract：:We examined the molecular epidemiology and evolution of Ross River (RR) virus in Australia and the Pacific Islands. Nucleotide sequences of the E2 and E3 genes of five RR virus strains revealed remarkable conservation between 1959 and 1989 with a maximum divergence of only 3.3%. Sequence data from a 505-base pair frag...

journal_title：Virology

authors： Sammels LM,Coelen RJ,Lindsay MD,Mackenzie JS

更新日期：1995-09-10 00:00:00

abstract：:Most adenovirus transducing vectors have the cytomegalovirus major immediate-early (CMV) or the Rous sarcoma virus long terminal repeat (RSV) promoter driving expression of the transgene. Both of these promoters are highly active in transfection and transduction assays in 293 cells, in which transducing vectors are co...

journal_title：Virology

authors： Schaack J,Allen B,Orlicky DJ,Bennett ML,Maxwell IH,Smith RL

更新日期：2001-12-05 00:00:00

abstract：:The budded phenotype of Autograha californica nuclear polyhedrosis virus (AcNPV BV) has a 64K glycoprotein in its envelope which is important in the ability of the virus to functionally enter host cells. Tunicamycin (TM), an inhibitor of N-linked glycosylation, was used to determine whether the sugar moiety was essent...

journal_title：Virology

authors： Charlton CA,Volkman LE

更新日期：1986-10-15 00:00:00