Abstract:
:The preS(21-47) sequence of the hepatitis B virus (HBV) envelope protein is involved in binding of the virus to cell receptors. A protein similarity search revealed a partial homology between this sequence and a segment of the human immunoglobulin A (IgA) heavy chain constant region, suggesting that the cell attachment site for HBV might be located on secretory component representing a receptor for polymeric IgA. Data presented herein do not support this hypothesis but provide evidence for immunological cross-reactivity between IgA and the preS(21-47) region of the HBV env protein.
journal_name
Virologyjournal_title
Virologyauthors
Neurath AR,Strick Ndoi
10.1016/0042-6822(90)90368-2subject
Has Abstractpub_date
1990-10-01 00:00:00pages
631-4issue
2eissn
0042-6822issn
1096-0341journal_volume
178pub_type
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