Sequences homologous to two separate transforming regions of herpes simplex virus DNA are linked in two human genital tumors.

abstract：:The human cytomegalovirus (HCMV) US12 gene family is a group of 10 predicted seven-transmembrane domain proteins that have some features in common with G-protein-coupled receptors. Little is known of their patterns of expression, localization, or functional interactions. Here, we studied the intracellular localization...

journal_title：Virology

authors： Das S,Pellett PE

更新日期：2007-05-10 00:00:00

abstract：:When recombinant plasmids containing the entire adeno-associated virus (AAV) genome are transfected into permissive cells infected with a helper adenovirus, infectious AAV particles are efficiently generated. These plasmids can be used to generate mutant AAV genomes or recombinant AAV vectors. Packaging of mutant AAV ...

journal_title：Virology

authors： Chejanovsky N,Carter BJ

更新日期：1989-07-01 00:00:00

abstract：:To study the process of membrane fusion in Morbilliviruses, the fusion (F) glycoproteins of Peste des petits ruminants virus (PPRV) and Rinderpest virus (RPV) were expressed transiently in mammalian cells. The recombinant F proteins were found to be localized at the surface of transfected cells. The fusion activity, a...

journal_title：Virology

authors： Seth S,Shaila MS

更新日期：2001-10-10 00:00:00

abstract：:All tissue culture systems for propagating HBV employed so far make use of tandemly arranged HBV genomes usually under the control of strong foreign promoters. Thus these systems are helpful for virus production but are of limited value in the investigation of the regulation of HBV replication or of the extent to whic...

journal_title：Virology

authors： Weiss L,Kekulè AS,Jakubowski U,Bürgelt E,Hofschneider PH

更新日期：1996-02-01 00:00:00

abstract：:Female BALB/c mice were infected with coxsackievirus B3 in the diestrus, proestrus, estrus, or metestrus phases of the ovarian cycle. Cycle stage was determined by vaginal smear. All mice were killed 7 days after infection. Females infected in the diestrus and especially the proestrus phases developed myocarditis. CD4...

journal_title：Virology

authors： Schwartz J,Sartini D,Huber S

更新日期：2004-12-05 00:00:00

abstract：:Viruses in certain genera in family Caulimoviridae were shown to integrate their genomic sequences into their host genomes and exist as endogenous pararetroviral sequences (EPRV). However, members of the genus Caulimovirus remained to be the exception and are known to exist only as episomal elements in the infected ce...

journal_title：Virology

authors： Pahalawatta V,Druffel K,Pappu H

更新日期：2008-07-05 00:00:00

abstract：:Hepatitis C virus (HCV) core protein constitutes a viral nucleocapsid and may possess multiple functions. In this study, we demonstrated the homotypic interaction and multimerization of HCV core protein in vitro and in vivo. By using a yeast two-hybrid system, we showed that the amino-terminal hydrophilic portion (ami...

journal_title：Virology

authors： Matsumoto M,Hwang SB,Jeng KS,Zhu N,Lai MM

更新日期：1996-04-01 00:00:00

abstract：:To investigate the role of Tobacco vein banding mosaic virus (TVBMV) 3'-UTR in virus systemic infection, three types of deletions were introduced into TVBMV infectious clone pCaTVBMV-GFP. Mutants with deletions at the nucleotide position 8-42, 43-141, or 163-174 in the 3'-UTR failed to cause systemic infection in N. b...

journal_title：Virology

authors： Wang Y,Yang ZY,Tian YP,Geng C,Yuan XF,Li XD

更新日期：2019-01-15 00:00:00

abstract：:The 130-kDa bovine herpesvirus-1 (BHV-1) glycoprotein GVP 6 was found to cross-react immunologically with the herpes simplex glycoprotein gB. Antibodies in polyclonal serum against gB immunoprecipitated GVP 6 and its cleavage products from a lysate of BHV-1-infected cells. Conversely, polyclonal serum against GVP 6 pr...

journal_title：Virology

authors： Misra V,Nelson R,Smith M

更新日期：1988-10-01 00:00:00

abstract：:Condylomata acuminata is caused by human papillomavirus (HPV). PCR with consensus primers will typically detect HPV in >96% of condylomata. Metagenomic sequencing has found that some "HPV-negative" condylomata do indeed contain HPV. We wished to perform a renewed evaluation of the "HPV-negative" condylomata using deep...

journal_title：Virology

authors： Arroyo Mühr LS,Bzhalava D,Lagheden C,Eklund C,Johansson H,Forslund O,Dillner J,Hultin E

更新日期：2015-11-01 00:00:00

abstract：:A major neutralizing epitope (here referred to as the T332 epitope) located on the lateral surface of domain III (DIII) of the West Nile virus (WNV) envelope protein has been identified based on the analysis of murine monoclonal antibodies. However, little is known about the humoral immune response against WNV in a na...

journal_title：Virology

authors： Sánchez MD,Pierson TC,Degrace MM,Mattei LM,Hanna SL,Del Piero F,Doms RW

更新日期：2007-03-15 00:00:00

abstract：:We have examined the nuclear and cytoplasmic distribution of the latency-associated transcripts (LATs) of HSV-1. During latency these transcripts accumulate in the nuclei of neurons in the peripheral and central nervous system of infected animals. However, our Northern blot analyses demonstrate that the 2-kb LAT is fo...

journal_title：Virology

authors： Nicosia M,Zabolotny JM,Lirette RP,Fraser NW

更新日期：1994-11-01 00:00:00

abstract：:The nucleotide sequences of the genomes of two strains of canine adenovirus, type 1 (Glaxo and CLL) have been determined within the region spanning approximately 0.80-0.91 map unit. Homology comparisons with other adenoviral DNAs indicate that this region contains part of the hexon-associated protein (pVIII) precursor...

journal_title：Virology

authors： Dragulev BP,Sira S,Abouhaidar MG,Campbell JB

更新日期：1991-07-01 00:00:00

abstract：:The function of a substantial percentage of the putative protein-coding open reading frames (ORFs) in viral genomes is unknown. As their sequence is not similar to that of proteins of known function, the function of these ORFs cannot be assigned on the basis of sequence similarity. Methods complement or in combination...

journal_title：Virology

authors： Han LY,Cai CZ,Ji ZL,Chen YZ

更新日期：2005-01-05 00:00:00

abstract：:Fiber and penton base overproduced in adenovirus (Ad) infected cells can be secreted prior to progeny release and thereby regulate progeny spread. We aimed to investigate the mechanisms of fiber and penton base secretion in Ad2- or Ad5-infected A549 cells. Our flow cytometry analyses detected abundant surface fiber mo...

journal_title：Virology

authors： Yan Y,Zhang B,Hou W,Lin H,Rebetz J,Hong SS,Wang Y,Ran L,Fan X

更新日期：2017-05-01 00:00:00

abstract：:In a previous study, we observed that hepatitis C virus (HCV) core protein specifically inhibits translation initiated by an HCV internal ribosome entry site (IRES). To investigate the mechanism by which down-regulation of HCV translation occurs, a series of mutations were introduced into the IRES element, as well as ...

journal_title：Virology

authors： Shimoike T,Koyama C,Murakami K,Suzuki R,Matsuura Y,Miyamura T,Suzuki T

更新日期：2006-02-20 00:00:00

abstract：:Cauliflower mosaic virus (CaMV) strains CM1841 and W260 produced markedly different symptoms when inoculated onto turnips (Brassica campestris L. 'Just Right'). The CM1841 strain induced a mild degree of stunting of infected plants while strain W260 caused moderate to severe stunting. Although CM1841 was significantly...

journal_title：Virology

authors： Anderson EJ,Qui SG,Schoelz JE

更新日期：1991-04-01 00:00:00

abstract：:HIV-1 transcytosis has been proposed as a potential mechanism allowing the virus to cross the epithelium during mucosal transmission. Epitopes of the HIV-1 envelope involved in this process have not been identified yet. Here, we assessed a large panel of HIV neutralizing antibodies recognizing well-characterized epito...

journal_title：Virology

authors： Chomont N,Hocini H,Gody JC,Bouhlal H,Becquart P,Krief-Bouillet C,Kazatchkine M,Bélec L

更新日期：2008-01-20 00:00:00

abstract：:The failure of HIV-1 to escape at some cytotoxic T-lymphocyte (CTL) epitopes has generally been explained in terms of viral fitness costs or ineffective or attenuated CTL responses. Relatively little attention has been paid to the evolutionary time required for escape mutants to be detected. This time is significantly...

journal_title：Virology

authors： Liu Y,Mullins JI,Mittler JE

更新日期：2006-03-30 00:00:00

abstract：:Epstein-Barr virus (EBV) latent membrane protein 2A (LMP2A) is expressed on the membrane of B-lymphocytes and blocks B cell receptor (BCR) signaling in EBV-transformed B-lymphocytes in vitro. The LMP2A amino-terminal domain, which is essential for the LMP2A-mediated block of B cell signal transduction, contains eight ...

journal_title：Virology

authors： Swart R,Fruehling S,Longnecker R

更新日期：1999-10-25 00:00:00

abstract：:Herpes simplex virus encodes proteins, such as DNA polymerase, that are essential for its replication and proteins, such as thymidine kinase, that are not essential for replication in cell culture, but are important for pathogenesis in animal models. However, certain mutations affecting these proteins exert little or ...

journal_title：Virology

authors： Jacobson J,Kramer M,Rozenberg F,Hu A,Coen DM

更新日期：1995-01-10 00:00:00

abstract：:The superinfection exclusion of VSV has been studied and found to be caused by a combination of three distinct effects on endocytosis by VSV-infected cells: first, a decreased rate of formation of endocytic vesicles as judged by an inhibition of fluid-phase uptake at 2 hr postinfection; second, a decreased rate of int...

journal_title：Virology

authors： Simon KO,Cardamone JJ Jr,Whitaker-Dowling PA,Youngner JS,Widnell CC

更新日期：1990-07-01 00:00:00

abstract：:Our study reports the occurrence of HIV-1 insertional activation events in vivo. Using a previously described PCR assay, small aliquots of broncho-alveolar lavage (BAL) cells obtained from AIDS patients were analyzed. Nine percent (5/54) of the aliquots contained proviral-host sequence transcripts indicating HIV-1 pro...

journal_title：Virology

authors： Raineri I,Solèr M,Senn HP

更新日期：1995-04-01 00:00:00

abstract：:The trans-activation-responsive (TAR) element located within the 5' untranslated region of HIV-1 mRNA is the cis-responsive element for Tat, the viral trans-activator protein. Several TAR RNA binding proteins (TRBPs) have been identified in the nuclear extract from HeLa cells as cellular factors required for a full Ta...

journal_title：Virology

authors： Masuda T,Harada S

更新日期：1993-02-01 00:00:00

abstract：:Two novel halophilic archaebacterial bacteriophages, HF1 and HF2, were isolated from an Australian solar saltern. They were morphologically identical with icosahedral-shaped heads (diameter 58 nm) and contractile tails (length 94 nm). Other similarities included sensitivity to reduced ionic conditions, similar protein...

journal_title：Virology

authors： Nuttall SD,Dyall-Smith ML

更新日期：1993-12-01 00:00:00

abstract：:Members of the genus Mastrevirus (family Geminiviridae) produce a complementary-sense (c-sense) transcription unit with the potential to encode two proteins, RepA and Rep. In the present work, we have studied the DNA-protein complexes formed by the Wheat dwarf virus (WDV) RepA protein within the WDV large intergenic r...

journal_title：Virology

authors： Missich R,Ramirez-Parra E,Gutierrez C

更新日期：2000-07-20 00:00:00

abstract：:Stress granule (SG)-like antiviral granules (AVG) had been found in some vaccinia virus infection conditions and shown to repress translation. Similar RNA granules are also associated with translational inhibition and poxvirus restriction mediated by the host restriction factor SAMD9, but their function is less clear....

journal_title：Virology

authors： Meng X,Xiang Y

更新日期：2019-03-01 00:00:00

abstract：:Two revertants of ts110 Moloney murine sarcoma virus (MuSV) with wild-type MuSV phenotype were examined for the presence of mos gene products, ts110 MuSV has a temperature-sensitive defect in a function required to maintain the transformed phenotype. The nonproducer 6m2 cell clone transformed by ts110 produces an 85,0...

journal_title：Virology

authors： Stanker LH,Horn JP,Gallick GE,Kloetzer WS,Murphy EC Jr,Blair DG,Arlinghaus RB

更新日期：1983-04-15 00:00:00

abstract：:The bipartite genomic RNAs of red clover necrotic mosaic virus (RCNMV) lack a 5' cap and a 3' poly(A) tail. RNA1 encodes viral replication proteins, and RNA2 encodes a movement protein (MP). These proteins are translated in a cap-independent manner. We previously identified two cis-acting RNA elements that cooperative...

journal_title：Virology

authors： Tajima Y,Iwakawa HO,Hyodo K,Kaido M,Mise K,Okuno T

更新日期：2017-09-01 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) Tat transcriptionally activates expression from a number of viral and cellular promoters. Recent studies demonstrate the ability of Tat to differentially modulate cellular responses to apoptotic signaling. The antiapoptotic effects of Tat appear to correlate with increased e...

journal_title：Virology

authors： Wang Z,Morris GF,Reed JC,Kelly GD,Morris CB

更新日期：1999-05-10 00:00:00