Myocarditis susceptibility in female mice depends upon ovarian cycle phase at infection.

abstract：:West Nile virus (WNV) is a mosquito-borne flavivirus that causes febrile illness, encephalitis, and occasionally death in humans. The envelope protein is the main component of the WNV virion surface, and domain III of the envelope protein (EIII) is both a putative receptor binding domain and a target of highly specifi...

journal_title：Virology

authors： Plante JA,Torres M,Huang CY,Beasley DWC

更新日期：2016-09-01 00:00:00

abstract：:A reporting replicon of West Nile virus (WN) was used to distinguish between the function of the 3' untranslated region (UTR) in viral translation and RNA replication. Deletions of various regions of the 3' UTR of the replicon did not significantly affect viral translation, but abolished RNA replication. A systematic ...

journal_title：Virology

authors： Tilgner M,Deas TS,Shi PY

更新日期：2005-01-20 00:00:00

abstract：:The main route of small ruminant lentivirus dissemination is the ingestion of infected cells present in colostrum and milk from infected animals. However, whether only macrophages or other cell subtypes are involved in this transmission is unknown. We derived epithelial cell cultures, 100% cytokeratin positive, from m...

journal_title：Virology

authors： Mselli-Lakhal L,Guiguen F,Fornazero C,Du J,Favier C,Durand J,Grezel D,Balleydier S,Mornex JF,Chebloune Y

更新日期：1999-06-20 00:00:00

abstract：:Maize streak virus (MSV) is a leafhopper-transmitted geminivirus containing one molecule of circular single-stranded DNA of about 2.7 kb. We have tested the infectivity of MSV mutants. A deletion of 29 bases in the small intergenic region (SIR) did not affect the infectivity of MSV. Mutants containing insertions of ol...

journal_title：Virology

authors： Shen WH,Hohn B

更新日期：1991-08-01 00:00:00

abstract：:Human papilllomaviruses (HPVs) are common human pathogens that infect cutaneous or mucosal epithelia in which they cause warts, self-contained benign lesions that commonly regress. The HPV life cycle is intricately tied to the differentiation of the host epithelium it infects. Mucosotropic HPVs are the most common sex...

journal_title：Virology

authors： Johannsen E,Lambert PF

更新日期：2013-10-01 00:00:00

abstract：:Phage-display methodology has been used to select variant CD4 proteins exhibiting increased binding to the surface envelope glycoprotein, gp120, of Human Immunodeficiency Virus Type-1. To facilitate the selection, a library of mutant CD4 proteins was constructed by cloning a PCR-generated error prone population of the...

journal_title：Virology

authors： Krykbaev R,McKeating J,Jones I

更新日期：1997-08-04 00:00:00

abstract：:Ultraviolet absorption spectra and difference spectra were determined for barley stripe mosaic virus (BSMV) virions and protein and for tobacco mosaic virus (TMV) virions and protein in buffer and in sodium dodecyl sulfate (SDS). The absorbance at 260 nm of BSMV virions disrupted in SDS was 92% of that of intact virio...

journal_title：Virology

authors： Brakke MK

更新日期：1979-10-15 00:00:00

abstract：:Murine gammaherpesvirus 68 (MHV68) is used as a model to study gammaherpesvirus pathogenesis both in tissue culture systems and in vivo. We used a gene-trapping approach to get insight into cellular factors involved in MHV68 infection. By generating a library of gene-trapped CHO cells, we were able to isolate several ...

journal_title：Virology

authors： Jarousse N,Coscoy L

更新日期：2008-04-10 00:00:00

abstract：:We demonstrate that the AL2 gene of Cabbage leaf curl virus (CaLCuV) activates the CP promoter in mesophyll and acts to derepress the promoter in vascular tissue, similar to that observed for Tomato golden mosaic virus (TGMV). Binding studies indicate that sequences mediating repression and activation of the TGMV and ...

journal_title：Virology

authors： Lacatus G,Sunter G

更新日期：2008-06-20 00:00:00

abstract：:Ts1, a temperature-sensitive mutant of Moloney murine leukemia virus-TB (MoMuLV-TB), causes a progressive hindlimb paralytic disease in susceptible strains of mice. Previously, it has been shown that a single amino acid substitution, Val-25----Ile in gPr80env, is responsible for the temperature sensitivity, inefficien...

journal_title：Virology

authors： Kamps CA,Lin YC,Wong PK

更新日期：1991-10-01 00:00:00

abstract：:A natural variation is observed at position 4 of the 3'-end of influenza A virus genomes, where U (U4) or C (C4) is present. The replicon activity of C4 was 28% of U4. We compared the transcription and replication activity of U4 [v84(U4)], C4 [v84(C4)] and the complimentary RNA (c84) using the purified influenza virus...

journal_title：Virology

authors： Jiang H,Zhang S,Wang Q,Wang J,Geng L,Toyoda T

更新日期：2010-12-20 00:00:00

abstract：:Among 167 rotavirus specimens collected from young children in a suburban area of Bissau, Guinea-Bissau, from 1996 to 1998, most identifiable strains belonged to the uncommon P[6], G2 type and approximately 50% remained incompletely typed. In the present study, 76 such strains were further characterized. Due to interp...

journal_title：Virology

authors： Fischer TK,Page NA,Griffin DD,Eugen-Olsen J,Pedersen AG,Valentiner-Branth P,Mølbak K,Sommerfelt H,Nielsen NM

更新日期：2003-06-20 00:00:00

abstract：:Recent studies have shown that interferon-gamma (IFN-gamma) synergizes with IFN-alpha/beta to inhibit the replication of both RNA and DNA viruses. We investigated the effects of IFNs on the replication of two strains of severe acute respiratory syndrome-associated coronavirus (SARS-CoV). While treatment of Vero E6 cel...

journal_title：Virology

authors： Sainz B Jr,Mossel EC,Peters CJ,Garry RF

更新日期：2004-11-10 00:00:00

abstract：:Monoclonal antibodies were used to compare the antigenicities of the haemagglutinins of two receptor binding mutants of X-31 (H3N2) influenza virus. The mutants which differed from each other in recognizing sialic acid in either alpha 2-6 linkage or alpha 2-3 linkage to galactose also differed exclusively at residue 2...

journal_title：Virology

authors： Daniels RS,Douglas AR,Skehel JJ,Wiley DC,Naeve CW,Webster RG,Rogers GN,Paulson JC

更新日期：1984-10-15 00:00:00

abstract：:In March 2017, a novel highly pathogenic avian influenza A(H7N9) virus was detected at two commercial broiler breeder facilities in Tennessee, United States. In this study, a wild bird low pathogenic avian influenza A virus, A/blue-winged teal/Wyoming/AH0099021/2016(H7N9), was shown to be the probable precursor of the...

journal_title：Virology

authors： Li L,DeLiberto TJ,Killian ML,Torchetti MK,Wan XF

更新日期：2018-12-01 00:00:00

abstract：:Two HLA-A*02-restricted epitopes have been identified within the VP1 polypeptide of a human polyomavirus, BK virus, which is associated with polyomavirus-associated nephropathy in kidney transplant patients. Immunization of transgenic mice with recombinant modified vaccinia Ankara expressing BKV VP1 (rMVA-BKV VP1) eli...

journal_title：Virology

authors： Sharma MC,Zhou W,Martinez J,Krymskaya L,Srivastava T,Haq W,Diamond DJ,Lacey SF

更新日期：2006-06-20 00:00:00

abstract：:The Psu (Polarity suppression) protein of satellite bacteriophage P4 was first characterized as an anti-terminator of transcription termination in Escherichia coli. Psu is also a structural component of mature P4 capsids, where it is present as a decoration protein. Psu is located externally on the capsid surface, and...

journal_title：Virology

authors： Isaksen ML,Dokland T,Lindqvist BH

更新日期：1993-06-01 00:00:00

abstract：:Virus like particles (17 nm in diameter) associated with maize white line mosaic virus (MWLMV) were shown to be a satellite virus of MWLMV (SV-MWLMV) on the basis of the following properties: (1) The SV-MWLMV was dependent upon the presence of MWLMV for replication in maize, while the latter virus could replicate inde...

journal_title：Virology

authors： Zhang L,Zitter TA,Palukaitis P

更新日期：1991-02-01 00:00:00

abstract：:The DNA sequence of bovine herpesvirus type 1 (BHV-1) ST strain (BHV-1.2 subtype) entire unique short (US) region and part of adjacent flanking sequences of the inverted repeats was determined. The BHV-1 ST US region is 9745 bp in size and has a 70.5% G + C content. Eight potential open reading frames (ORFs) longer th...

journal_title：Virology

authors： Leung-Tack P,Audonnet JC,Riviere M

更新日期：1994-03-01 00:00:00

abstract：:Simian cells permissive for influenza A virus infection were stably transformed with a full-length cloned influenza A nucleoprotein gene under the control of an inducible metallothionein promoter and linked to a dihydrofolate reductase gene to facilitate cell selection. Transformed cells synthesized a virus-specific n...

journal_title：Virology

authors： Ryan KW,Mackow ER,Chanock RM,Lai CJ

更新日期：1986-10-15 00:00:00

abstract：:Retroviruses are expressed under the control of viral control regions designated long terminal repeats (LTRs), which contain all signals for transcriptional initiation as well as transcriptional termination. However, retroviral LTRs from different species within a common genus, such as Lentivirus, do not show signific...

journal_title：Virology

authors： Frech K,Brack-Werner R,Werner T

更新日期：1996-10-01 00:00:00

abstract：:Cell lines persistently infected with foot-and-mouth disease virus (FMDV) have been established by growth of BHK-21 (c-13) or IBRS-2 (c-26) that survived standard cytolytic infections with FMDV. They maintain cytoplasmic FMDV RNA sequences, as shown by dot blot hybridization tests, using cloned FMDV cDNA as probes. Ce...

journal_title：Virology

authors： de la Torre JC,Dávila M,Sobrino F,Ortín J,Domingo E

更新日期：1985-08-01 00:00:00

abstract：:Following primary ocular infection, HSV-1 establishes a latent infection in the trigeminal ganglia with the complete absence of detectable infectious virus. Recently, we showed that vaccination of BALB/cJ with HSV-1 glycoprotein K (gK), but not other HSV-1 glycoproteins, significantly exacerbated the severity of HSV-1...

journal_title：Virology

authors： Ghiasi H,Cai S,Nesburn AB,Wechsler SL

更新日期：1996-10-01 00:00:00

abstract：:The unordered N-termini of parvovirus capsid proteins (Nt) are translocated through a channel at the icosahedral five-fold axis to serve for virus traffick. Heterologous peptides were genetically inserted at the Nt of MVM to study their functional tolerance to manipulations. Insertion of a 5T4-single-chain antibody at...

journal_title：Virology

authors： Sánchez-Martínez C,Grueso E,Carroll M,Rommelaere J,Almendral JM

更新日期：2012-10-10 00:00:00

abstract：:Kaposi's sarcoma-associated herpesvirus (KSHV) is a member of the Gammaherpesvirinae and is causally associated with Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease. The KSHV genome encodes over 85 genes; the function of some is entirely unknown. We have characterized the transcriptio...

journal_title：Virology

authors： Masa SR,Lando R,Sarid R

更新日期：2008-02-05 00:00:00

abstract：:A number of factors that affect genetic interaction during mixed infection with temperature-sensitive mutants of simian rotavirus SA11 have been examined. (1) Statistical analyses of recombination frequency (RF) indicated that (a) the variability noted in RF was not related to variations in experimental conditions and...

journal_title：Virology

authors： Ramig RF

更新日期：1983-05-01 00:00:00

abstract：:The role of the nucleocapsid protein of HIV-1 Gag in virus assembly was investigated using Gag truncation mutants, a nucleocapsid deletion mutant, and point mutations in the nucleocapsid region of Gag, in transfected COS cells, and in stable T-cell lines. Consistent with previous investigations, a truncation containin...

journal_title：Virology

authors： Dawson L,Yu XF

更新日期：1998-11-10 00:00:00

abstract：:The effects of P2 prophage on lambda-mediated depression of host metabolism, and on lambda macromolecular synthesis have been studied. Experiments employing certain lambdabio deletion mutants and lambda-related phages suggest that the same gene products are involved in inhibition of host metabolism (Hin+ function) and...

journal_title：Virology

authors： Cohen SN,Chang AC

更新日期：1971-11-01 00:00:00

abstract：:Epizootics of a natural varicella-like disease occur in populations of nonhuman primates. Several primate herpesviruses have been isolated from these epizootics, but the relatedness of these isolates to each other is not well-defined. In this study, we demonstrated that the restriction endonuclease (REn) profiles of f...

journal_title：Virology

authors： Gray WL,Gusick NJ

更新日期：1996-10-01 00:00:00

abstract：:Studies were undertaken to compare the effect of poly(A)s from various sources on selective inhibition of protein synthesis in the reticulocyte lysate system programmed with viral and cellular mRNAs. RNA synthesized in vitro by vaccinia virus cores in the presence of only ATP inhibited overall HeLa cell polypeptide sy...

journal_title：Virology

authors： Bablanian R,Goswami SK,Esteban M,Banerjee AK

更新日期：1987-12-01 00:00:00