Full-length nucleotide sequence of a simian TT virus isolate obtained from a chimpanzee: evidence for a new TT virus-like species.

abstract：:An open reading frame which encodes at least 90% of the adenovirus type 2 DNA polymerase gene was cloned behind the SP6 promoter and transcribed in vitro using the SP6 RNA polymerase. The resultant RNA was translated in a rabbit reticulocyte cell free system. In addition to the translation of a 120-kDa protein corresp...

journal_title：Virology

authors： Hassin D,Korn R,Horwitz MS

更新日期：1986-11-01 00:00:00

abstract：:Natural infection and vaccination with a live-attenuated measles virus (MV) induce CD8(+) T-cell-mediated immune responses that may play a central role in controlling MV infection. In this study, we show that newly identified human HLA-A2 epitopes from MV hemagglutinin (H) and fusion (F) proteins induced protective im...

journal_title：Virology

authors： Oh S,Stegman B,Pendleton CD,Ota MO,Pan CH,Griffin DE,Burke DS,Berzofsky JA

更新日期：2006-09-01 00:00:00

abstract：:Twelve avian reovirus strain 176 proteins, 10 structural (lambda 1, lambda 2, lambda 3, mu 1, mu 2/mu 2C, sigma 1, sigma 2, sigma 3, and sigma 4), and 2 nonstructural (mu NS and sigma NS) were identified and characterized by electrophoretic analysis of purified virions and infected cell lysates. Three of the identifie...

journal_title：Virology

authors： Ni Y,Ramig RF,Kemp MC

更新日期：1993-03-01 00:00:00

abstract：:Coronavirus small envelope protein E has two known biological functions: it plays a pivotal role in virus envelope formation, and the murine coronavirus E protein induces apoptosis in E protein-expressing cultured cells. The E protein is an integral membrane protein. Its C-terminal region extends cytoplasmically in th...

journal_title：Virology

authors： Maeda J,Repass JF,Maeda A,Makino S

更新日期：2001-03-15 00:00:00

abstract：:cDNAs of beet necrotic yellow vein virus RNAs 3 and 4 could be rendered biologically active when they were placed under the control of the cauliflower mosaic virus 35S promoter and polyadenylation signal. Although the 35S in vivo transcripts should have contained up to forty 5' and several hundred 3' nonviral nucleoti...

journal_title：Virology

authors： Commandeur U,Jarausch W,Li Y,Koenig R,Burgermeister W

更新日期：1991-11-01 00:00:00

abstract：:Spindle-shaped viruses are a dominant morphotype in hypersaline waters but their molecular characteristics and their relationship to other archaeal viruses have not been determined. Here, we describe the isolation, characteristics and genome sequence of His2, a spindle-shaped halovirus, and compare it to the previousl...

journal_title：Virology

authors： Bath C,Cukalac T,Porter K,Dyall-Smith ML

更新日期：2006-06-20 00:00:00

abstract：:Studies attempting to identify reservoirs of HIV-1 latency have documented that the virus persists as both a latent and productive infection in subsets of CD4(+) cells. Reports regarding establishment of a stable HIV-1 infection in quiescent T cells in vitro, however, are controversial. In the present study, we invest...

journal_title：Virology

authors： Joshi A,Vahlenkamp TW,Garg H,Tompkins WA,Tompkins MB

更新日期：2004-04-10 00:00:00

abstract：:The recent emergence and spread of dengue hemorrhagic fever in the Americas have been a major source of concern. Efforts to control this disease are dependent on understanding the pathogenicity of dengue viruses and their transmission dynamics. Pathogenicity studies have been hampered by the lack of in vitro or in viv...

journal_title：Virology

authors： Rico-Hesse R,Harrison LM,Salas RA,Tovar D,Nisalak A,Ramos C,Boshell J,de Mesa MT,Nogueira RM,da Rosa AT

更新日期：1997-04-14 00:00:00

abstract：:We have used mRNA differential display to search for cellular genes whose expression is modulated in SV40-transformed cells. We identified a gene, the alpha1 subunit of type XI procollagen (alpha1(XI)), whose mRNA level is reduced in most F111 rat cell lines that express either wild-type SV40 T antigen or an amino-ter...

journal_title：Virology

authors： Sompayrac L,Jane S,Danna KJ

更新日期：1996-04-15 00:00:00

abstract：:The mutations in two DNA-negative ts mutants of herpes simplex virus type 1 (HSV-1), tsK13 and tsM19, have been previously mapped to a 2.0-kb fragment (coordinates 0.095-0.108) at the left end of the genome (S. Weller, D. Aschman, W. Sacks, D. Coen, and P. Schaffer, 1983, Virology 130, 290-305). Sequence analysis of t...

journal_title：Virology

authors： Zhu L,Weller SK

更新日期：1988-10-01 00:00:00

abstract：:Antibodies against the L protein of Sendai virus were made by immunizing rabbits with a synthetic peptide representing a carboxyl-terminal region of the protein predicted from the base sequence of its gene. These antibodies were used to localize the L protein in viral nucleocapsids by electron microscopy. Immunogold l...

journal_title：Virology

authors： Portner A,Murti KG,Morgan EM,Kingsbury DW

更新日期：1988-03-01 00:00:00

abstract：:An infectious raccoon poxvirus (RCNV) was used to express the feline panleukopenia virus (FPV) open reading frame VP2. The recombinant, RCNV/FPV, was constructed by homologous recombination with a chimeric plasmid for inserting the expression cassette into the thymidine kinase (TK) locus of RCNV. Expression of the VP2...

journal_title：Virology

authors： Hu L,Esposito JJ,Scott FW

更新日期：1996-04-01 00:00:00

abstract：:Although many workers have investigated the maturation and processing of the flavivirus nonstructural glycoprotein NS1 in infected cells, these studies have provided little insight into a possible function for NS1. In this study we investigated the subcellular localization of NS1 both by immunofluorescence and cryo-im...

journal_title：Virology

authors： Mackenzie JM,Jones MK,Young PR

更新日期：1996-06-01 00:00:00

abstract：:Norwalk virus (NV) is the prototype strain of a group of noncultivatable caliciviruses that infect humans and cause outbreaks of epidemic acute nonbacterial gastroenteritis. The NV virion is composed of 180 copies of a single structural protein that, when expressed in insect cells infected with a recombinant baculovir...

journal_title：Virology

authors： Hardy ME,Tanaka TN,Kitamoto N,White LJ,Ball JM,Jiang X,Estes MK

更新日期：1996-03-01 00:00:00

abstract：:Human papillomavirus type 16 (HPV-16) is the most common papillomavirus genome found in human cervical cancers and its DNA is capable of immortalizing primary keratinocytes in vitro. When expressed by their native promoter, two separate HPV-16 oncogenes, E6 and E7, cooperate to immortalize primary human keratinocytes....

journal_title：Virology

authors： Stöppler MC,Straight SW,Tsao G,Schlegel R,McCance DJ

更新日期：1996-09-01 00:00:00

abstract：:To investigate differential evolutionary rates and selective forces of WNV in hosts and vectors, we measured the genetic diversity that arose during alternating passage in mosquitoes and birds. Within-host genetic diversity was monitored in each of three experimentally passed replicates, and the complete genome sequen...

journal_title：Virology

authors： Jerzak GV,Brown I,Shi PY,Kramer LD,Ebel GD

更新日期：2008-05-10 00:00:00

abstract：:Although H5N1 influenza viruses have been responsible for hundreds of human infections, these avian influenza viruses have not fully adapted to the human host. The lack of sustained transmission in humans may be due, in part, to their avian-like receptor preference. Here, we have introduced receptor binding domain mut...

journal_title：Virology

authors： Maines TR,Chen LM,Van Hoeven N,Tumpey TM,Blixt O,Belser JA,Gustin KM,Pearce MB,Pappas C,Stevens J,Cox NJ,Paulson JC,Raman R,Sasisekharan R,Katz JM,Donis RO

更新日期：2011-04-25 00:00:00

abstract：:Ovine pulmonary carcinoma, a contagious lung cancer of sheep, is caused by the oncogenic jaagsiekte sheep retrovirus (JSRV) that is closely related to a family of endogenous sheep retroviral sequences (ESRVs). By using exogenous virus-specific U3 oligonucleotide primers, the entire JSRV proviral genome or its 3' part ...

journal_title：Virology

authors： Bai J,Bishop JV,Carlson JO,DeMartini JC

更新日期：1999-06-05 00:00:00

abstract：:Foot-and-mouth disease virus (FMDV) shows a remarkable antigenic variability. Like other RNA viruses, this virus has a high rate of mutation. It has been proposed that selection exerted by the host's antibodies could play a major role in the rapid evolution of FMDV. The present work reports the selection of FMDV antib...

journal_title：Virology

authors： Carrillo EC,Rojas ER,Cavallaro L,Schiappacassi M,Campos R

更新日期：1989-08-01 00:00:00

abstract：:Sequence analysis of the mouse hepatitis virus, strain A59 (MHV-A59) genome predicts the presence of two papain-like proteinases encoded within the first open reading frame (ORF 1a) of the replicase gene. The more 5' of these domains, the leader papain-like proteinase, is responsible for the cleavage of the amino term...

journal_title：Virology

authors： Bonilla PJ,Hughes SA,Piñón JD,Weiss SR

更新日期：1995-06-01 00:00:00

abstract：:Human adenovirus (HAdV) is a cause of significant morbidity and mortality in immunocompromised patients, especially after stem cell transplantation (SCT). Viral clearance has been attributed to CD4(+) T-cell responses against the Hexon-protein, but the frequency of specific T(HELPER) cells is extremely low or not dete...

journal_title：Virology

authors： Serangeli C,Bicanic O,Scheible MH,Wernet D,Lang P,Rammensee HG,Stevanovic S,Handgretinger R,Feuchtinger T

更新日期：2010-02-20 00:00:00

abstract：:TMV capsid protein reacts with and encapsidates many of the chloroplast DNA transcripts both in vivo and in vitro to form pseudovirions. We report on the encapsidation initiation reaction with one of the major RNA species found in in vivo formed pseudovirions, the mRNA for the chloroplast-encoded large subunit of ribu...

journal_title：Virology

authors： Atreya CD,Siegel A

更新日期：1989-02-01 00:00:00

abstract：:HCV genotype is a major determinant of clinical outcome, and GT1b HCV infection is the most difficult to treat and also the predominant genotype in East Asia and Europe. We developed 1b/JFH-1 inter-genotypic recombinants containing the structural genes (Core, E1, E2), p7 and the 1stTMD of NS2 directly from GT1b clinic...

journal_title：Virology

authors： Lu J,Tao W,Li R,Xiang Y,Zhang N,Xiang X,Xie Q,Zhong J

更新日期：2013-08-15 00:00:00

abstract：:It is unresolved whether recently transmitted human immunodeficiency viruses (HIV) have genetic features that specifically favour their transmissibility. To identify potential "transmission signatures", we compared 20 full-length HIV-1 subtype C genomes from primary infections, with 66 sampled from ethnically and geog...

journal_title：Virology

authors： Treurnicht FK,Seoighe C,Martin DP,Wood N,Abrahams MR,Rosa Dde A,Bredell H,Woodman Z,Hide W,Mlisana K,Karim SA,Gray CM,Williamson C

更新日期：2010-01-20 00:00:00

abstract：:Sensitivity of a library of rat cells transformed in vitro with viable recombinant adenoviruses to natural killer (NK) cells and allogeneic cytotoxic T cells has been studied and correlated with their oncogenic potential in syngeneic rats. All cell lines transformed with the sub370-12E1AB virus (containing E1A and E1B...

journal_title：Virology

authors： Sawada Y,Föhring B,Shenk TE,Raska K Jr

更新日期：1985-12-01 00:00:00

abstract：:The nucleotide sequence of the leader and the gene encoding the nucleocapsid protein (NP) of mumps virus Miyahara strain have been determined. The leader sequence is 55 nucleotides in length and the NP gene is 1845 nucleotides in length, exclusive of poly(A). The NP gene codes for a protein of 549 amino acids, with a ...

journal_title：Virology

authors： Tanabayashi K,Takeuchi K,Hishiyama M,Yamada A,Tsurudome M,Ito Y,Sugiura A

更新日期：1990-07-01 00:00:00

abstract：:The genomic S RNA segment of Prospect Hill virus (PHV), a member of the Hantavirus genus, was molecularly cloned and the nucleotide sequence of the cDNA determined. The PHV S RNA segment is 1675 nucleotides long. A long open reading frame was identified in the viral complementary-sense RNA that could encode a 433 amin...

journal_title：Virology

authors： Parrington MA,Kang CY

更新日期：1990-03-01 00:00:00

abstract：:Here we describe the complete genome sequences of two strains of Usutu virus (USUV), a mosquito-borne member of the genus Flavivirus in the Japanese encephalitis virus (JEV) serogroup. USUV was detected in Austria in 2001 causing a high mortality rate in blackbirds; the reference strain (SAAR-1776) was isolated in 195...

journal_title：Virology

authors： Bakonyi T,Gould EA,Kolodziejek J,Weissenböck H,Nowotny N

更新日期：2004-10-25 00:00:00

abstract：:Gammaherpesviruses establish life-long infection in most adults and are associated with the development of B cell lymphomas. While the interaction between gammaherpesviruses and splenic B cells has been explored, very little is known about gammaherpesvirus infection of B-1 B cells, innate-like B cells that primarily r...

journal_title：Virology

authors： Rekow MM,Darrah EJ,Mboko WP,Lange PT,Tarakanova VL

更新日期：2016-05-01 00:00:00

abstract：:The red clover necrotic mosaic dianthovirus (RCNMV) genome is split between two single-stranded RNA species. The polycistronic RNA-1 encodes the viral RNA polymerase and capsid protein (CP) and the monocistronic RNA-2 encodes the 35 kDa cell-to-cell movement protein (MP). Nicotiana benthamiana plants transformed with ...

journal_title：Virology

authors： Vaewhongs AA,Lommel SA

更新日期：1995-10-01 00:00:00