Abstract:
:Gammaherpesviruses establish life-long infection in most adults and are associated with the development of B cell lymphomas. While the interaction between gammaherpesviruses and splenic B cells has been explored, very little is known about gammaherpesvirus infection of B-1 B cells, innate-like B cells that primarily reside in body cavities. This study demonstrates that B-1 B cells harbor the highest frequency of latently infected cells in the peritoneum throughout chronic infection, highlighting a previously unappreciated feature of gammaherpesvirus biology.
journal_name
Virologyjournal_title
Virologyauthors
Rekow MM,Darrah EJ,Mboko WP,Lange PT,Tarakanova VLdoi
10.1016/j.virol.2016.02.022subject
Has Abstractpub_date
2016-05-01 00:00:00pages
140-4eissn
0042-6822issn
1096-0341pii
S0042-6822(16)30017-4journal_volume
492pub_type
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