Identification of proteins encoded by avian reoviruses and evidence for post-translational modification.

Abstract:

:Twelve avian reovirus strain 176 proteins, 10 structural (lambda 1, lambda 2, lambda 3, mu 1, mu 2/mu 2C, sigma 1, sigma 2, sigma 3, and sigma 4), and 2 nonstructural (mu NS and sigma NS) were identified and characterized by electrophoretic analysis of purified virions and infected cell lysates. Three of the identified proteins (mu 1, mu NS, and sigma 4) have not been previously described. In pulse-chase experiments, 10 of the proteins (lambda 1, lambda 2, lambda 3, mu 1, mu 2, mu NS, sigma 1, sigma 2, sigma NS, sigma 3) were shown to be primary translation products, whereas mu 2C was shown to be a post-translational cleavage product of mu 2.

journal_name

Virology

journal_title

Virology

authors

Ni Y,Ramig RF,Kemp MC

doi

10.1006/viro.1993.1147

subject

Has Abstract

pub_date

1993-03-01 00:00:00

pages

466-9

issue

1

eissn

0042-6822

issn

1096-0341

pii

S0042-6822(83)71147-5

journal_volume

193

pub_type

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