Keratins in the human trophoblast.

abstract：:Introduction. Gastrointestinal stromal tumors (GISTs) are characterized at the molecular level by c-kit or PDGFRA oncogene mutations. Although GISTs raised major interest in past decades, population-based studies are still rare. Materials and Methods. All GISTs diagnosed in Southern Switzerland (1999-2005) were identi...

journal_title：Histology and histopathology

authors： Mazzola P,Spitale A,Banfi S,Mazzucchelli L,Frattini M,Bordoni A

更新日期：2008-11-01 00:00:00

abstract：:Within the last few years, advances have been made regarding perivascular nerves and the endothelium of the vascular system, both potentially important in the understanding of the mechanisms of local control of blood flow. Endothelin-1 (ET-1) has been identified in rat cerebrovascular nerves, neuropeptide Y (NPY) has ...

journal_title：Histology and histopathology

authors： Loesch A

更新日期：2002-04-01 00:00:00

abstract：:The integrity of the thymus during early life is necessary for a proper maturation of the neuroendocrine system, including the adrenal axis. The thymic metallopeptide thymulin seems to be a central physiologic mediator of thymus-pituitary communication. Furthermore, neonatal thymulin gene therapy has been shown to pre...

journal_title：Histology and histopathology

authors： Martines E,Reggiani PC,Schwerdt JI,Goya RG,Cónsole G

更新日期：2011-04-01 00:00:00

abstract：:Nitric oxide (NO) is a biological messenger molecule produced by one of the essential amino acids L-arginine by the catalytic action of the enzyme NO synthase (NOS). The dual role of NO as a protective or toxic molecule is due to several factors, such as; the isoform of NOS involved, concentration of NO and the type o...

journal_title：Histology and histopathology

authors： Thippeswamy T,McKay JS,Quinn JP,Morris R

更新日期：2006-04-01 00:00:00

abstract：:Much effort has been made by researchers to elucidate the complex biology of breast cancer stem cells (BCSCs), a small subset of breast tumor cells that display stem cell properties, drive tumor initiation, and growth. In recent years, it has been suggested that BCSCs could be responsible for the process of metastasis...

journal_title：Histology and histopathology

authors： Schwarz-Cruz Y Celis A,Espinosa M,Maldonado V,Melendez-Zajgla J

更新日期：2016-06-01 00:00:00

abstract：:The possibility of resuscitating livers after warm ischaemia has been recently suggested. The aim of the present investigation was to analyse the effects of anoxia on the morphology of hepatic cells, to determine whether these effects are reversible after providing a resuscitation period between warm ischaemia (WI) an...

journal_title：Histology and histopathology

authors： Jurado F,Buján J,Mora NP,Jiménez M,Arahuetes R,Bellón JM

更新日期：1997-01-01 00:00:00

abstract：:An inadequate balance between oxidant species and antioxidant mechanisms may constitute the primary mechanisms of a number of pathologies. The liver plays a central role in this balance: parenchymal hepatic cells contain and export especially high levels of the antioxidant glutathione and activated Kupffer cells relea...

journal_title：Histology and histopathology

authors： Catalá M,Pagani R,Portolés MT

更新日期：2007-04-01 00:00:00

abstract：:The aim of this study was to demonstrate the morphology and matrix synthesis of embryonic rat liver cells (day 18 of gestation) in organoid cultures (high density cultures) with electron microscopic and immunomorphological techniques. For this purpose the cells of embryonic rat livers were isolated enzymatically and g...

journal_title：Histology and histopathology

authors： Elkasaby A,Xu D,Schröter-Kermani C,Merker HJ

更新日期：1991-04-01 00:00:00

abstract：:The transport mechanism of soluble molecules throughout the interstitial matrix is closely associated with human tumor behavior in vivo. However, the examination of soluble components in histological architectures has been hampered by artifacts caused during conventional tissue preparation. In this study, the immunodi...

journal_title：Histology and histopathology

authors： Bai Y,Ohno N,Terada N,Saitoh S,Nakazawa T,Nakamura N,Katoh R,Ohno S

更新日期：2009-06-01 00:00:00

abstract：:Glucocorticoids play a major role in attenuation of the inflammatory response and they are useful in the primary combination chemotherapy of breast cancer, since in vitro studies have demonstrated an antiproliferative effect in human breast cancer cells. In contrast, it was recently shown that glucocorticoids protect ...

journal_title：Histology and histopathology

authors： Conde I,Paniagua R,Fraile B,Lucio J,Arenas MI

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:It is difficult to prevent and treat intra- and peri-neural fibrosis after peripheral nerve surgery. Many authors have attempted to develop and verify the effectiveness of substances to decrease the formation of adherences in different tissues. MATERIAL AND METHODS:this study aimed to assess the effective...

journal_title：Histology and histopathology

authors： Hernández-Cortés P,Peregrina M,Aneiros-Fernández J,Tassi M,Pajares-López M,Toledo M,O'Valle F

更新日期：2010-06-01 00:00:00

abstract：:We have studied the occurrence and specific features of liver cell dysplasia (LCD) in Chinese patients showing liver cirrhosis with or without hepatocellular carcinoma (HCC). Three types of LCD (SLCD, LLCDo, LLCDe) were morphologically defined, and these types were further analyzed using karyometry, estimation of nucl...

journal_title：Histology and histopathology

authors： Zhao M,Zhang NX,Du ZY,Laissue JA,Zimmermann A

更新日期：1994-01-01 00:00:00

abstract：:Parkinson's disease (PD) is a neurodegenerative disorder characterized by progressive cell loss confined mostly to dopaminergic neurons of the substantia nigra. Several factors, including oxidative stress, and decreased activity of complex I mitochondrial respiratory chain, are involved in the degenerative process. Ye...

journal_title：Histology and histopathology

authors： Anglade P,Vyas S,Javoy-Agid F,Herrero MT,Michel PP,Marquez J,Mouatt-Prigent A,Ruberg M,Hirsch EC,Agid Y

更新日期：1997-01-01 00:00:00

abstract：:Phagocytosis is an important feature of innate immunity in which invading microorganisms are engulfed, killed and degraded - and in some immune cells, their antigens presented to adaptive immune system. A closely related process, efferocytosis, removes apoptotic cells, and is essential for the maintenance of homeostas...

journal_title：Histology and histopathology

authors： Taefehshokr N,Yin C,Heit B

更新日期：2020-09-29 00:00:00

abstract：:We describe a new technique, decalcification by perfusion, for the softening of bony tissue. The blood circulatory system was perfused in 16 rats via a cannula through the left heart ventricle with a fixative followed by New Decalc (an acidic demineralizer) for 30-240 minutes. Perfusion decalcification for 120 minutes...

journal_title：Histology and histopathology

authors： Nilsson M,Hellström S,Albiin N

更新日期：1991-07-01 00:00:00

abstract：:The recent discovery of nitric oxide (NO) as a biological messenger molecule with unique characteristics has opened a new field in pineal research. This free radical gas is synthesized by the enzyme nitric oxide synthase (NOS) from L-arginine. The activation of adrenoreceptors in the membrane of the pinealocytes media...

journal_title：Histology and histopathology

authors： López-Figueroa MO,Møller M

更新日期：1996-10-01 00:00:00

abstract：:Studies with scanning electron microscopy in the normal human sulcular epithelium are scarce, and no precise information exists about cell surface patterns along the epithelium, the frequencies of these patterns, or possible regional differences within the mouth. In five periodontal biopsy specimens each from the ante...

journal_title：Histology and histopathology

authors： Sánchez-Quevedo MC,Moreu G,Campos A,García JM,González-Jaranay M

更新日期：1994-01-01 00:00:00

abstract：:During endotoxic shock, the liver exerts a lipopolysaccharide (LPS) clearance function with the participation of both parenchymal and sinusoidal cells. Liver damage could be caused by LPS direct action, hypoxia and/or inflammatory mediators released by Kupffer cells. The aim of this study is to establish an experiment...

journal_title：Histology and histopathology

authors： Pagani R,Portolés MT,Arahuetes R,Ainaga MJ,Machín C,Rua C

更新日期：1996-07-01 00:00:00

abstract：:STAT and SMAD often exert opposite biological effects on diverse cellular functions. Recent studies have shown that STAT can interface with SMAD at molecular level and that some novel molecules, such as SOCS (also called CIS) and APRO6 (also called TOB), modulate this signaling. A cofactor p300/CBP might act as a brid...

journal_title：Histology and histopathology

authors： Iwamoto T,Oshima K,Seng T,Feng X,Oo ML,Hamaguchi M,Matsuda S

更新日期：2002-01-01 00:00:00

abstract：:Detailed characterization of the subdermal model is a significant tool for better understanding of calcification mechanisms occurring in heart valves. In previous ultrastructural investigation on six-week-implantated aortic valve leaflets, modified pre-embedding glutaraldehyde-cuprolinic-blue reactions (GA-CB) enabled...

journal_title：Histology and histopathology

authors： Ortolani F,Bonetti A,Tubaro F,Petrelli L,Contin M,Nori SL,Spina M,Marchini M

更新日期：2007-03-01 00:00:00

abstract：:The sarcolemmal domain of rat duodenal smooth muscle cells includes caveolae and associated cytoskeletal or filamentous elements. We have used the quick-freezing, deep-etching method to examine the three dimensional relationships between these components. Replica membranes for separated strips of rat duodenal muscle l...

journal_title：Histology and histopathology

authors： Takayama I,Fujii Y,Terada N,Baba T,Kato Y,Fujino MA,Ohno S

更新日期：2000-10-01 00:00:00

abstract：:We examined the relationship between the incidence of ultrastructural changes in the alveolar septum and the extravascular lung water content. Pulmonary edema was induced in 18 mongrel dogs by either dextran (n = 12) or alloxan (n = 6) administration. Six other dogs served as controls. Extravascular lung water content...

journal_title：Histology and histopathology

authors： Oda H,Arakawa M,Kambara K,Nakahara K,Segawa T,Ando F,Kawada T,Hirakawa S,Shoumura S,Isono H

更新日期：1993-01-01 00:00:00

abstract：:The three-dimensional structure of the pancreatic ductular system (from the intercalated duct to the intercellular secretory canaliculus) is controversial and unclear. The aim of this study is to reveal the three-dimensional structure of the pancreatic ductular sysytem at the onset of pancreatitis. One day following r...

journal_title：Histology and histopathology

authors： Endo H,Ashizawa N,Niigaki M,Hamamoto N,Niigaki M,Kaji T,Katsube T,Watanabe M,Naora H,Otani H,Kinoshita Y

更新日期：2002-01-01 00:00:00

abstract：:Serotonin-producing pancreatic endocrine tumours are rare neoplasms which in most cases exhibit malignant biological behaviour. These tumours, in the majority of the well-documented cases, are composed of argyrophil- and argentaffin-positive cells which contain large pleomorphic neurosecretory granules. In contrast, a...

journal_title：Histology and histopathology

authors： Kanavaros P,Hoang C,Le Bodic MF,Polivka M,Hautefeuille P

更新日期：1990-07-01 00:00:00

abstract：:This study evidences the presence of primordial germ cells, in tissue squash preparations and sections from hematological malignancies. Primordial germ cells were identified by their morphology, the intense PAS, PAS-D reaction and presence of calcium-activated neutral proteinase. Primordial germ cells gave rise to nuc...

journal_title：Histology and histopathology

authors： Logothetou-Rella H

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Gelatinases include matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9). The abnormal expressions of gelatinases are implicated in the pathogenesis of extracellular matrix (ECM) accumulation. Apolipo-protein E (apoE) is an important plasma protein in cholesterol homeostasis and plays a ...

journal_title：Histology and histopathology

authors： Zhou TB,Qin YH,Lei FY,Su LN,Zhao YJ,Huang WF

更新日期：2012-02-01 00:00:00

abstract：:The ultrastructure of the atrial myocardium in the monkey (Macaca fascicularis) was studied after bilateral cervical vagotomy and survival times of 100, 175 and 367 days. Changes were observed in the nucleus and the cytoplasm of the myocyte. Sequestered within the nuclei of the affected myocytes were cytoplasmic organ...

journal_title：Histology and histopathology

authors： Wong WC,Yick TY,Ling EA

更新日期：1989-07-01 00:00:00

abstract：:Androgen receptor (AR) interact with many pathways involved in bladder cancer development and progression. FUS (fused in liposarcoma), a multifunctional protein essential for different cellular processes, has been demonstrated as a key link between androgen receptor signaling and cell-cycle progression in prostate can...

journal_title：Histology and histopathology

authors： Abd Raboh NM,Hakim SA,Abd El Atti RM

更新日期：2020-12-23 00:00:00

abstract：:Autophagy and apoptosis are two important molecular mechanisms that maintain cellular homeostasis under stress conditions. Autophagy represents an intracellular mechanism responsible for turnover of organelles and long-lived proteins through a lysosome-dependent degradation pathway. Cell death signals or sustained str...

journal_title：Histology and histopathology

authors： Oral O,Akkoc Y,Bayraktar O,Gozuacik D

更新日期：2016-05-01 00:00:00

abstract：:The liver represents a site of expression of neurotrophins and their receptors. We have characterized the expression and intracellular localization of the nerve growth factor (NGF) receptor, Trk-A, in liver cells in vivo and in vitro. In both normal and fibrotic liver tissue, Trk-A immunostaining was present in differ...

journal_title：Histology and histopathology

authors： Bonacchi A,Taddei ML,Petrai I,Efsen E,Defranco R,Nosi D,Torcia M,Rosini P,Formigli L,Rombouts K,Zecchi S,Milani S,Pinzani M,Laffi G,Marra F

更新日期：2008-03-01 00:00:00