Implications of androgen receptor and FUS expression on tumor progression in urothelial carcinoma.

abstract：:Takeda-G-protein-receptor-5 (TGR5) is a receptor for bile acids and its expression has been described in a variety of tissues and species. Characterization of TGR5 distribution and function has been investigated in drug discovery for the treatment of metabolic diseases in humans. Because dogs are one of the species us...

journal_title：Histology and histopathology

authors： Giaretta PR,Suchodolski JS,Blick AK,Steiner JM,Lidbury JA,Rech RR

更新日期：2019-01-01 00:00:00

abstract：:During endotoxic shock, the liver exerts a lipopolysaccharide (LPS) clearance function with the participation of both parenchymal and sinusoidal cells. Liver damage could be caused by LPS direct action, hypoxia and/or inflammatory mediators released by Kupffer cells. The aim of this study is to establish an experiment...

journal_title：Histology and histopathology

authors： Pagani R,Portolés MT,Arahuetes R,Ainaga MJ,Machín C,Rua C

更新日期：1996-07-01 00:00:00

abstract：:Chaperone-mediated autophagy (CMA), a selective form of autophagy, where cellular proteins with KFERQ-like motif are targeted to the lysosome for degradation, is necessary to maintain cellular homeostasis. The role of CMA in neurodegenerative diseases has been extensively studied in the past decades, with defects in t...

journal_title：Histology and histopathology

authors： Hou T,Fan Y,Dan W,Liu B,Wang Z,Zeng J,Li L

更新日期：2020-07-01 00:00:00

abstract：:The aim of our study was to evaluate corneal cell proliferation and apoptosis in cases of granular, macular and lattice dystrophy, and to provide evidence which may help to clarify whether apoptosis is a pathogenic factor in any of these dystrophies. The study group comprised 39 eyes (from 33 patients) which had under...

journal_title：Histology and histopathology

authors： Szentmáry N,Takács L,Berta A,Szende B,Süveges I,Módis L

更新日期：2007-08-01 00:00:00

abstract：:Representative tumour sections from 468 patients with invasive breast cancer were immunostained for cyclooxygenase-2 (COX-2) and evaluated. The relationships between COX-2 expression, clinical outcome and various clinicopathological variables, including tumour vascularity and disseminated tumour cells (DTC) in the bon...

journal_title：Histology and histopathology

authors： Dhakal HP,Naume B,Synnestvedt M,Borgen E,Kaaresen R,Schlichting E,Wiedswang G,Bassarova A,Holm R,Giercksky KE,Nesland JM

更新日期：2012-10-01 00:00:00

abstract：:Transforming growth factor-beta1 (TGF-1beta) has been shown to modulate both cell proliferation and the synthesis of extracellular matrix by vascular cells. This study was aimed to establish the temporal correlation between TGF-beta1 expression, the expression of the extracellular matrix protein fibronectin, and plaqu...

journal_title：Histology and histopathology

authors： Chen YL,Wu HW,Jiang MJ

更新日期：2000-04-01 00:00:00

abstract：:The clinical presentation, histopathology and immunoelectron microscopic features of two cases of duodenal somatostatinoma are described, one of which is a hitherto unreported example of a collision tumour with a neurofibroma. Ultrastructural morphometric immunoelectron microscopy studies revealed the presence of four...

journal_title：Histology and histopathology

authors： Varikatt W,Yong JL,Killingsworth MC

更新日期：2006-11-01 00:00:00

abstract：:This study deals with myocardial preservation after 24 hours of continuous, hypothermic and oxygenated perfusion with Cape Town (CT) solution, focusing on the morphological changes produced by preservation and reperfusion, and their possible relationship to the composition of the solution and the immediate hemodynamic...

journal_title：Histology and histopathology

authors： García-Poblete E,Alvarez L,Fernández H,Escudero C,Torralba A

更新日期：1998-01-01 00:00:00

abstract：:Ischemic heart disease is a widespread cause of death. During infarction, myocardial injury is mediated by release of several pro-inflammatory cytokines including multifunctional interleukin-1 (IL-1). In various tissues, IL-1-mediated deleterious effects are known to be attenuated via the over-expression of natural an...

journal_title：Histology and histopathology

authors： Bonetti A,Marchini M,Ortolani F

更新日期：2008-09-01 00:00:00

abstract：:Diabetic nephropathy (DN) is a major cause of end-stage renal disease (ESRD), however, specific treatment for DN has not yet been elucidated. Therefore, it is critically important to understand the molecular mechanism underlying DN to develop cause-related therapeutic strategy. To date, various factors such as hemodyn...

journal_title：Histology and histopathology

authors： Kawanami D,Matoba K,Utsunomiya K

更新日期：2016-10-01 00:00:00

abstract：:Actin microfilaments and microtubules are important cytoskeletal proteins that regulate endothelial repair through alterations in cell shape and through regulation of cell migration following wounding of the endothelium. Upstream pathways have been identified in the regulation of actin and microtubule organization, es...

journal_title：Histology and histopathology

authors： Lee JS,Gotlieb AI

更新日期：2003-07-01 00:00:00

abstract：:An immunohistochemical study of matrix metalloproteinases (MMP-2 and MMP-9) or gelatinase (gelatinase A and gelatinase B) was performed on the seminal vesicles and ventral prostate of the Libyan jird (Meriones libycus) collected in the Beni-Abbes area during breeding period (spring and early summer), during resting ph...

journal_title：Histology and histopathology

authors： Belhocine M,Gernigon-Spychalowicz T,Jacob MP,Benazzoug Y,Exbrayat JM

更新日期：2010-05-01 00:00:00

abstract：:Glucocorticoids play a major role in attenuation of the inflammatory response and they are useful in the primary combination chemotherapy of breast cancer, since in vitro studies have demonstrated an antiproliferative effect in human breast cancer cells. In contrast, it was recently shown that glucocorticoids protect ...

journal_title：Histology and histopathology

authors： Conde I,Paniagua R,Fraile B,Lucio J,Arenas MI

更新日期：2008-01-01 00:00:00

abstract：:Glucose uptake and metabolism are essential for proliferation and survival of cells, and are supposed to be enhanced in actively proliferating cell systems such as embryonic and cancer tissues. Glucose uptake is usually carried out through glucose transporters. In the developing fetal lung, metabolism of glucose is th...

journal_title：Histology and histopathology

authors： Ito T,Noguchi Y,Udaka N,Kitamura H,Satoh S

更新日期：1999-07-01 00:00:00

abstract：:Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for the purpose of anti-inflammation, antipyretic, and analgesia. For this aim, they are used for the alleviation of pain, fever, and inflammation associated with rheumatoid arthritis, sports injuries, and temporary pain. However, treatment with NSAIDs may ...

journal_title：Histology and histopathology

authors： Aygün D,Kaplan S,Odaci E,Onger ME,Altunkaynak ME

更新日期：2012-04-01 00:00:00

abstract：:Immunohistochemistry of the terminal complement complex (C5b-9) and fibronectin (FN) is useful to detect myocardial ischemia preceding necrosis in the postmortem diagnosis of sudden cardiac death. The present immunohistochemical study examined connexin43 (Cx43) and zonula occludens-1 (ZO-1) as markers of early myocard...

journal_title：Histology and histopathology

authors： Kawamoto O,Michiue T,Ishikawa T,Maeda H

更新日期：2014-06-01 00:00:00

abstract：:Infection with Helicobacter pylori (H. pylori) strains is linked to an increased risk of inflammation and gastric cancer. To investigate the effects of H. pylori on biological characteristics of gastric epithelial cells SGC-7901, derived from human adenocarcinoma, morphological appearances of both the pathogen and the...

journal_title：Histology and histopathology

authors： Wang P,Mei J,Tao J,Zhang N,Tian H,Fu GH

更新日期：2012-08-01 00:00:00

abstract：:Fibrosis is a pathological feature of most chronic diseases and leads to the dysfunction of various organs. However, there is currently no effective method for treating fibrosis. In recent years, a small gas, sulfur dioxide (SO₂), which can be generated endogenously in mammals, has been found to have vasorelaxation ac...

journal_title：Histology and histopathology

authors： Wang XB,Cui H,Du JB

更新日期：2019-12-01 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is the most common malignancy of the oral cavity with a poor 5-year survival rate, due in large part to the presence of metastatic disease at initial diagnosis. In recent years, a number of studies have examined the oral tumor microenvironment to asses the potential dynamic balance ...

journal_title：Histology and histopathology

authors： Shi Z,Stack MS

更新日期：2010-07-01 00:00:00

abstract：:Osteoclasts are physiological polykaryons specialized in the resorption of calcified tissue. In the context of the clinical use of calcium-phosphate (CaP) ceramics as bone substitutes, this study used transmission electron microscopy to investigate the in vitro mechanisms of CaP ceramic degradation by osteoclastic cel...

journal_title：Histology and histopathology

authors： Heymann D,Guicheux J,Rousselle AV

更新日期：2001-01-01 00:00:00

abstract：:Bone marrow features in stable-phase chronic myelogenous leukemia (CML) are characterized by a striking heterogeneity which is determinable by appropriate means including representative pre-treatment trephine biopsies, immunohistochemistry and morphometry. Cell lineages involved to a variable extent consist not only o...

journal_title：Histology and histopathology

authors： Thiele J,Kvasnicka HM,Fischer R

更新日期：1999-10-01 00:00:00

abstract：:β-lapachone is a quinone of lapachol extracted from the bark of lapacho tree. Recent findings demonstrated that punched skin wounds of mice healed faster with β-lapachone treatment. The present study investigates the effects of β-lapachone on burn-wound skin of C57BL/6 mice injured by a 100 °C iron stick. Our results ...

journal_title：Histology and histopathology

authors： Fu SC,Chau YP,Lu KS,Kung HN

更新日期：2011-07-01 00:00:00

abstract：:The importance of molybdenum-containing enzymes in the pathophysiology of a number of clinical disorders necessitates a comprehensive understanding of their histological localization and expression. The objectives of this review are to cover such enzymes so far reported and their enzyme- and immunohistochemical locali...

journal_title：Histology and histopathology

authors： Moriwaki Y,Yamamoto T,Higashino K

更新日期：1997-04-01 00:00:00

abstract：:The Farnesoid X Receptor (FXR) is a member of the nuclear receptor superfamily of ligand-activated transcription factors, which plays crucial role in bile acid, cholesterol, lipid and glucose metabolism, as well as in the development of atherosclerosis, intestinal bacterial growth and liver regeneration. FXR is also i...

journal_title：Histology and histopathology

authors： Koutsounas I,Giaginis C,Theocharis S

更新日期：2012-07-01 00:00:00

abstract：:The low density lipoprotein receptor-related protein (LRP) 1 is a ubiquitously expressed, versatile cell surface transmembrane receptor involved in embryonic development and adult tissue homeostasis. LRP1 binds and endocytoses a broad spectrum of over 40 ligands identified thus far, including lipoproteins, extracellul...

journal_title：Histology and histopathology

authors： Wujak L,Markart P,Wygrecka M

更新日期：2016-07-01 00:00:00

abstract：:Neural stem cells are defined as clonogenic cells with self-renewal capacity and the ability to generate all neural lineages (multipotentiality). Cells with these characteristics have been isolated from the embryonic and adult central nervous system. Under specific conditions, these cells can differentiate into neuron...

journal_title：Histology and histopathology

authors： Bazán E,Alonso FJ,Redondo C,López-Toledano MA,Alfaro JM,Reimers D,Herranz AS,Paíno CL,Serrano AB,Cobacho N,Caso E,Lobo MV

更新日期：2004-10-01 00:00:00

abstract：:Platelet-derived growth factor-A (PDGF-A) is a locally produced growth factor in the rat testis secreted by both Sertoli cells and Leydig cells. It has been suggested that PDGF-A may be involved in modulation of testosterone production and may be essential to Leydig cell differentiation, however it is not known at wha...

journal_title：Histology and histopathology

authors： Fecteau KA,Mrkonjich L,Mason JI,Mendis-Handagama SM

更新日期：2006-12-01 00:00:00

abstract：:The ultrastructure of four aldosterone secreting adenomas and of the adjacent zona glomerulosa has been described by the use of stereological techniques. Adenomatous cells (about 2800 microns 3 in volume) invariably displayed a striking abundance of lipid droplets, which occupied about 30% of the cytoplasm. Mitochondr...

journal_title：Histology and histopathology

authors： Belloni AS,Mantero F,Rocco S,Gottardo G,Mazzocchi G,Nussdorfer GG

更新日期：1988-07-01 00:00:00

abstract：:Spinal cord injury (SCI) is one of the most destructive traumatic diseases in human beings. The balance of inflammation in the microenvironment is crucial to the repair process of spinal cord injury. Inflammatory cytokines are direct mediators of local lesion inflammation and affect the prognosis of spinal cord injury...

journal_title：Histology and histopathology

authors： Lin S,Xu C,Lin J,Hu H,Zhang C,Mei X

更新日期：2020-10-01 00:00:00

abstract：:Recent data challenge the relevance of the RB pathway to cancer based on RB inactivation, at least in breast tumors. To obtain information on the actual role of the components of the RB pathway in tumor progression we decided to investigate whether their quantitative changes were associated with variations in the leve...

journal_title：Histology and histopathology

authors： Montanaro L,Vici M,Donati G,Ceccarelli C,Santini D,Treré D,Derenzini M

更新日期：2007-07-01 00:00:00