Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease.

abstract：:Neutrophil extracellular traps (NETs) are innate immune systems against invading pathogens. NETs are characterized as released DNA mixed with cytoplasmic antimicrobial proteins such as myeloperoxidase, proteinase3 and neutrophil elastase. While NETs are thought to have an important role in host defense, recent work ha...

journal_title：Histology and histopathology

authors： Nakazawa D,Kumar S,Desai J,Anders HJ

更新日期：2017-03-01 00:00:00

abstract：:Besides microfilaments and microtubules, intermediate filaments are major components of the cytoskeleton. In epithelial cells intermediate filaments are formed by heterodimers of specific keratins, whose expression pattern highly depends on the type of epithelium and differentiation degree of the cell. During the proc...

journal_title：Histology and histopathology

authors： Gauster M,Blaschitz A,Siwetz M,Huppertz B

更新日期：2013-07-01 00:00:00

abstract：:Cyclosporin A is an immunosuppressive drug, which disrupts the activation of peripheral T-lymphocyte pool and blocks the maturation of thymocytes within the thymus. Normally, thymic nonlymphoid cells provide the optimal inductive microenvironment for development of T-lymphocytes. After application of cyclosporin A the...

journal_title：Histology and histopathology

authors： Milićević NM,Milićević Z

更新日期：1998-10-01 00:00:00

abstract：:To investigate the matrix metalloproteinase (MMP)-9, (MMP)-13, E-Cadherin and Ki-67 expressions in road pavers' skin chronically exposed to bitumen products in order to contribute to a better understanding of the earlier tissue alteration. Skin punch biopsies from 16 daily exposed workers and a control group were stud...

journal_title：Histology and histopathology

authors： Loreto C,Lombardo C,Caltabiano R,Filetti V,Vitale E,Seminara D,Castorina S,Fenga C,Ledda C,Rapisarda V

更新日期：2019-10-01 00:00:00

abstract：:The developing fetal brain is one of the most susceptible organs to irradiation insult. Prenatal irradiation-induced abnormalities in the cerebrum have been well examined in mouse fetuses. However, little information on abnormalities in the cerebellum caused by irradiation is available. Moreover, few reports have exam...

journal_title：Histology and histopathology

authors： Saito A,Yamauchi H,Ishida Y,Ohmachi Y,Nakayama H

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Little is known regarding the role of redox balance regulators in metastatic melanomas, but there is some evidence for a link between epithelial-to-mesenchymal transition (EMT) and cellular redox status. METHODS:We compared the immunohistochemical expression of nuclear factor erythroid-2-related factor 2 (N...

journal_title：Histology and histopathology

authors： Hintsala HR,Haapasaari KM,Soini Y,Karihtala P

更新日期：2017-02-01 00:00:00

abstract：:The anti-oxidant food additive, butylated hydroxytoluene (BHT), was fed to Sprague-Dawley rats at three concentrations: 0.2%, 0.4% and 0.8% for periods of 6, 12, 18 and 24 weeks, and the results were compared with corresponding groups treated with a potent carcinogen, 7,12-dimethylbenz[a]anthracene (DMBA) groups, with...

journal_title：Histology and histopathology

authors： Safer AM,al-Nughamish AJ

更新日期：1999-04-01 00:00:00

abstract：:High mobility group box 1 protein (HMGB1) is a non-histone chromosomal protein which is highly conserved, ubiquitous, and widely distributed. HMGB1 has multiple functions in the nucleus, including the maintenance of nucleosome structure, the regulation of gene transcription, and involvement in DNA recombination. HMBG1...

journal_title：Histology and histopathology

authors： Umahara T,Uchihara T,Koyama S,Hashimoto T,Akimoto J,Haraoka J,Iwamoto T

更新日期：2014-02-01 00:00:00

abstract：:Lymphatic vessels afferent to the popliteal nodes in young adult rats and guinea pigs were interrupted at the lowest edge of the popliteal fossa, and regressive changes in the nodes occurring 4 to 16 or 18 weeks after surgery were re-examined histologically. In the rat, some popliteal nodes were drained by lymphatic c...

journal_title：Histology and histopathology

authors： Hoshi H,Takemoto R,Nagata H,Horie K,Murakami G,Suzuki S

更新日期：1993-07-01 00:00:00

abstract：:Voltage-activated Ca2+ channels play an important role in synaptic transmission, signal processing and development. The immunohistochemical localization of Cav1.2 (alpha1C) and Cav2.3 (alpha1E) Ca2+ channels was studied in the developing and adult mouse organ of Corti using subunit-specific antibodies and fluorescent ...

journal_title：Histology and histopathology

authors： Waka N,Knipper M,Engel J

更新日期：2003-10-01 00:00:00

abstract：:Telocytes (TC) are a class of interstitial cells present in heart. Their characteristic feature is the presence of extremely long and thin prolongations (called telopodes). Therefore, we were interested to see whether or not TCs form networks in normal cardiac tissues, as previously suggested. Autopsy samples of card...

journal_title：Histology and histopathology

authors： Rusu MC,Pop F,Hostiuc S,Curca GC,Jianu AM,Paduraru D

更新日期：2012-06-01 00:00:00

abstract：:Our study aimed to investigate the association of Pyruvate Kinase isozyme type M2 (PKM2) with radiation resistance in locally advanced cervical squamous cell carcinoma (LACSCC). We retrospectively reviewed 132 female patients who received primary radiation therapy to treat LACSCC at Federation Internationale of Gyneco...

journal_title：Histology and histopathology

authors： Zhao Y,Shen L,Chen X,Qian Y,Zhou Q,Wang Y,Li K,Liu M,Zhang S,Huang X

更新日期：2015-11-01 00:00:00

abstract：:CD24 is known to be an important diagnostic and prognostic marker of several major cancers affecting females. We aimed to determine CD24 expression in normal, hyperplastic, and carcinomatous endometrium and its correlation with estrogen and progesterone receptor expression. A total of 271 cases including 62 normal/atr...

journal_title：Histology and histopathology

authors： Kim KH,Choi JS,Kim JM,Choi YL,Shin YK,Lee HC,Seong IO,Kim BK,Chae SW,Kim SH

更新日期：2009-03-01 00:00:00

abstract：:GLI-similar (Glis) 1-3 proteins constitute a subfamily of the Krüppel-like zinc finger transcription factors that are closely related to the Gli family. Glis1-3 play critical roles in the regulation of a number of physiological processes and have been implicated in several pathologies. Mutations in GLIS2 have been lin...

journal_title：Histology and histopathology

authors： Kang HS,ZeRuth G,Lichti-Kaiser K,Vasanth S,Yin Z,Kim YS,Jetten AM

更新日期：2010-11-01 00:00:00

abstract：:Diabetic nephropathy (DN) is a major cause of end-stage renal disease (ESRD), however, specific treatment for DN has not yet been elucidated. Therefore, it is critically important to understand the molecular mechanism underlying DN to develop cause-related therapeutic strategy. To date, various factors such as hemodyn...

journal_title：Histology and histopathology

authors： Kawanami D,Matoba K,Utsunomiya K

更新日期：2016-10-01 00:00:00

abstract：:In order to analyze the incidence and prevalence of Human Papillomavirus (HPV) in penile carcinoma, we studied 49 patients with penile carcinoma. Formalin-fixed, paraffin-embedded tissue samples were collected from 64 samples of penile carcinoma from the Hospital General Universitario (Albacete, Spain). Cases were his...

journal_title：Histology and histopathology

authors： Pascual A,Pariente M,Godínez JM,Sánchez-Prieto R,Atienzar M,Segura M,Poblet E

更新日期：2007-02-01 00:00:00

abstract：:TNFalpha exerts apoptosis throughout an intracellular transduction pathway that involves the kinase proteins TRAF-2 (integration point of apoptotic and survival signals), ASK1 (pro-apoptotic protein), MEK-4 (p38 activator and metastasis suppressor gene), JNK (stress mitogen activated protein kinase) and the transcript...

journal_title：Histology and histopathology

authors： Royuela M,Rodríguez-Berriguete G,Fraile B,Paniagua R

更新日期：2008-10-01 00:00:00

abstract：:Infection with Helicobacter pylori (H. pylori) strains is linked to an increased risk of inflammation and gastric cancer. To investigate the effects of H. pylori on biological characteristics of gastric epithelial cells SGC-7901, derived from human adenocarcinoma, morphological appearances of both the pathogen and the...

journal_title：Histology and histopathology

authors： Wang P,Mei J,Tao J,Zhang N,Tian H,Fu GH

更新日期：2012-08-01 00:00:00

abstract：:The Libyan jird (Meriones libycus) is a nocturnal Saharan Rodent submitted to a seasonal cycle of reproduction characterized by a short active period during spring and beginning of summer, and a long phase of sexual quiescence from the end of summer until the end of winter. During this cycle, the male reproductive org...

journal_title：Histology and histopathology

authors： Belhocine M,Gernigon-Spychalowicz T,Robert AM,Schoevaert D,Bennazzoug Y,Exbrayat JM

更新日期：2007-06-01 00:00:00

abstract：:The changes of implanted Harding-Passey melanoma in C57Bl/6J mice following treatment with wholebody hyperthermia were studied. The treated tumours showed a progressive growth delay, cellular and architectural irregularities as well as cell injury characteristics. The presence of distended and irregular blood vessels,...

journal_title：Histology and histopathology

authors： Vicente V,Gómez M,Gómez S,Calderon F,Canteras M,Cremades A

更新日期：1987-10-01 00:00:00

abstract：:The bronchial-associated lymphoid tissue (BALT) is a lymphoepithelial organ, related to the immune defence of the lung and to alveolar clearance, which changes size in certain states of disease. Changes in the size of BALT were quantified and compared, and Spearman's test was used to test the relation with the bronchi...

journal_title：Histology and histopathology

authors： Escolar Castellón JD,Escolar Castellón A,Roche Roche PA,Miñana Amada C

更新日期：1992-07-01 00:00:00

abstract：:The hindgut is the major site in the horse for nutrient digestion and absorption. Most of this activity occurs in the large intestinal compartments, i.e., cecum, right and left ventral colon and left and right dorsal colon. The colonic pelvic flexure is a short and narrow loop connecting the left ventral and left dors...

journal_title：Histology and histopathology

authors： Lopes MA,Pfeiffer CJ

更新日期：2000-07-01 00:00:00

abstract：:Macrophages play important roles in host defense mechanisms. In the brain, besides microglial cells, meningeal macrophages are present. However, the pathobiological characteristics of meningeal macrophages in rats remain to be investigated. In normal meninx, immunohistochemically, macrophages reacting to CD163 (macrop...

journal_title：Histology and histopathology

authors： Yamate J,Ishimine S,Izawa T,Kumagai D,Kuwamura M

更新日期：2009-01-01 00:00:00

abstract：:The morphology of the rat duodenum after chronic treatment with 15% (v/v) ethanol and 4% (v/v) pentanol was studied. Male Wistar rats of experimental groups were given ethanol and pentanol for 15 weeks with food and fluid freely available. Ethanol-15% and 4% pentanol-fed rats showed a significantly reduced fluid and f...

journal_title：Histology and histopathology

authors： Vaquera J,Vaquera A,Girbes T

更新日期：2002-01-01 00:00:00

abstract：:A large number of biologically active substances have been identified and characterised in the respiratory tract of several mammals. These substances (amines and peptides) exert important regulatory influences on respiratory functions, and they act as neurotransmitters/neuromodulators, both being released from nerve t...

journal_title：Histology and histopathology

authors： Verástegui C,Fernández-Vivero J,Prada A,Rodríguez F,Romero A,González-Moreno M,de Castro JM

更新日期：1997-10-01 00:00:00

abstract：:We designed to investigate the effects of down-regulating the tumor susceptibility gene 101 (TSG101) on the proliferation and apoptosis of the human breast cancer MCF-7 cell line, and the role of the MAPK/ERK signal pathway in this process. The siRNA against TSG101 was transfected into the breast cancer MCF-7 cell lin...

journal_title：Histology and histopathology

authors： Zhang Y,Song M,Cui ZS,Li CY,Xue XX,Yu M,Lu Y,Zhang SY,Wang EH,Wen YY

更新日期：2011-01-01 00:00:00

abstract：:Three-dimensional characteristics of the epithelial cell layer and connective tissue interface of the tongue were studied using scanning electron microscopy. In this study, the fragments of tongue were fixed in modified Karnovsky's fixative solution. Subsequently, the specimens were treated with 10% NaOH solution for ...

journal_title：Histology and histopathology

authors： Silva MC,Watanabe I,Kronka MC

更新日期：2002-04-01 00:00:00

abstract：:Transforming growth factor-betas (TGF-betas) are multifunctional cytokines that exist in 3 isoforms in mammals. The TGF-betas are ubiquitously expressed and all isoforms are secreted as biologically inactive precursors called latent TGF-beta (L-TGF-beta). L-TGF-betas are generally not effective molecules because they ...

journal_title：Histology and histopathology

authors： Khalil N

更新日期：2001-04-01 00:00:00

abstract：:Calcium/calmodulin-dependent protein kinase II (CaMKII) is considered one of the key intracellular signaling proteins for development of neuropathy. We analyzed the expression of total CaMKII (tCaMKII) and its alpha, beta, gamma and delta isoforms in dorsal root ganglia (DRG) in a rat model of Diabetes mellitus type I...

journal_title：Histology and histopathology

authors： Ferhatovic L,Jelicic Kadic A,Boric M,Puljak L

更新日期：2014-05-01 00:00:00

abstract：:In the present work a morphopathological study is carried out of the glomerular filtration barrier in 20 Large-White pigs weighing 20 kg, subjected to experimental intravenous inoculations of endotoxin from Salmonella enteritidis. The study is completed with the determination of protein plasmatic levels, through urine...

journal_title：Histology and histopathology

authors： Redondo E,Roncero V,Durán E,Gázquez A

更新日期：1989-10-01 00:00:00