High expression of PKM2 as a poor prognosis indicator is associated with radiation resistance in cervical cancer.

abstract：:Endometriosis is a chronic pelvic inflammatory process. Local inflammation is known to play a role in pain and infertility associated with the disease, and may be extensively involved in molecular and cellular processes leading to endometriosis development. In this review, we focus on two inflammatory mediators clearl...

journal_title：Histology and histopathology

authors： Defrère S,González-Ramos R,Lousse JC,Colette S,Donnez O,Donnez J,Van Langendonckt A

更新日期：2011-08-01 00:00:00

abstract：:Epidemiologic studies have suggested that elderly patients who consumed diets rich in antioxidants throughout their lives are less likely to be afflicted with age-related macular degeneration (AMD). This led to the Age-Related Eye Disease Study, which showed that supplements containing antioxidant vitamins and zinc re...

journal_title：Histology and histopathology

authors： Shen JK,Dong A,Hackett SF,Bell WR,Green WR,Campochiaro PA

更新日期：2007-12-01 00:00:00

abstract：:The importance of molybdenum-containing enzymes in the pathophysiology of a number of clinical disorders necessitates a comprehensive understanding of their histological localization and expression. The objectives of this review are to cover such enzymes so far reported and their enzyme- and immunohistochemical locali...

journal_title：Histology and histopathology

authors： Moriwaki Y,Yamamoto T,Higashino K

更新日期：1997-04-01 00:00:00

abstract：:The effect of chronic alcoholism on the human hippocampus was studied in 21 patients, divided in 4 groups: Group A under 45 years, group B 46-59 years, group C 60-69, and Group D over 70 years; and compared with age-matched control patients who died without neurological complications. The gyrus dentatus and the ammoni...

journal_title：Histology and histopathology

authors： Bengochea O,Gonzalo LM

更新日期：1990-07-01 00:00:00

abstract：:Oligodendrocytes are the myelinating cells of the central nervous system. Since many studies of demyelinating diseases focus their research on this cell type, there is growing interest for obtaining reliable markers that can specifically recognize oligodendroglia. Established markers are the myelin-associated neurite ...

journal_title：Histology and histopathology

authors： Salinas Tejedor L,Gudi V,Kucman V,Pul R,Gingele S,Sühs KW,Stangel M,Skripuletz T

更新日期：2015-12-01 00:00:00

abstract：:Spectrins are members of the superfamily of F-actin cross linking proteins that are important as scaffolding proteins for protein sorting, cell adhesion, and migration. In addition, spectrins have been implicated in TGF-beta signaling. The aim of the present study was to analyze the expression and localization of beta...

journal_title：Histology and histopathology

authors： Jiang X,Gillen S,Esposito I,Giese NA,Michalski CW,Friess H,Kleeff J

更新日期：2010-12-01 00:00:00

abstract：:The effects of the administration of cyclophosphamide to male rats at doses of 400 mg/m2 for a period of 5 days and of 200 mg/m2 over two five-day cycles interrupted by a 21-day break reveal differences in the ultrastructural morphology of gonadotrophic cells between treated animals and normal controls. The ultrastruc...

journal_title：Histology and histopathology

authors： Poblador MS,Rojas C,Raya A,Casares JA,Aparicio J,Lancho Alonso JL

更新日期：1990-04-01 00:00:00

abstract：:The pathophysiologic mechanism by which chronic hypoxia causes pulmonary hypertension is unknown. If anti-platelet agents, or other pharmacologic interventions, altered the pulmonary vascular changes induced by hypoxia, information concerning the pathogenesis of the pulmonary hypertension or the potential therapeutic ...

journal_title：Histology and histopathology

authors： Keith IM,Will JA,Huxtable RJ,Weir K

更新日期：1987-04-01 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is the most common malignancy of the oral cavity with a poor 5-year survival rate, due in large part to the presence of metastatic disease at initial diagnosis. In recent years, a number of studies have examined the oral tumor microenvironment to asses the potential dynamic balance ...

journal_title：Histology and histopathology

authors： Shi Z,Stack MS

更新日期：2010-07-01 00:00:00

abstract：:Mitochondrial transcription factor A (mtTFA) plays a crucial role in both the transcription and maintenance of mitochondrial DNA. A high expression of mtTFA has been demonstrated in several solid tumors, and is closely associated with cancer cell survival/apoptosis and growth. However, its expression pattern in pancre...

journal_title：Histology and histopathology

authors： Kimura T,Kitada S,Uramoto H,Zhi L,Kawatsu Y,Takeda T,Horie S,Nabeshima A,Noguchi H,Sasaguri Y,Izumi H,Kohno K,Yamada S

更新日期：2015-02-01 00:00:00

abstract：:Differentiating nonspecific interstitial pneumonia (NSIP) from usual interstitial pneumonia (UIP) is important for the determination of both treatment and prognosis. Using two-dimensional fluorescence difference gel electrophoresis (2D-DIGE), we examined 8 UIPs, 8 NSIPs, and 30 normal lung tissues. Comparisons with co...

journal_title：Histology and histopathology

authors： Ohara I,Aida S,Shimazaki H,Kobayashi H,Tsuda H,Toda T,Nakanishi K,Tamai S

更新日期：2014-03-01 00:00:00

abstract：:Smads are signal transducers for the members of the TGF-beta superfamily. Of these Smads, Smad4 is essential for TGF-beta signaling. The purpose of this study was to elucidate Smad4 expression and localization in 65 gastric adenomas, 49 intestinal-type and 39 diffuse type of gastric adenocarcinomas (including 12 cases...

journal_title：Histology and histopathology

authors： Kim JY,Park DY,Kim GH,Choi KU,Lee CH,Huh GY,Sol MY,Song GA,Jeon TY,Kim DH,Sim MS

更新日期：2005-04-01 00:00:00

abstract：:Macrophages play important roles in host defense mechanisms. In the brain, besides microglial cells, meningeal macrophages are present. However, the pathobiological characteristics of meningeal macrophages in rats remain to be investigated. In normal meninx, immunohistochemically, macrophages reacting to CD163 (macrop...

journal_title：Histology and histopathology

authors： Yamate J,Ishimine S,Izawa T,Kumagai D,Kuwamura M

更新日期：2009-01-01 00:00:00

abstract：:There is scarce information on the possible effects of chronic exposure to mercury on skeletal muscle. Dental personnel are frequently exposed to inhalation of metallic mercury vapours. The skeletal muscle of five technicians and one dentist (females, age 36-55) was studied. All of them presented symptoms of chronic m...

journal_title：Histology and histopathology

authors： Nadorfy-López E,Torres SH,Finol H,Méndez M,Bello B

更新日期：2000-07-01 00:00:00

abstract：:The integrity of the thymus during early life is necessary for a proper maturation of the neuroendocrine system, including the adrenal axis. The thymic metallopeptide thymulin seems to be a central physiologic mediator of thymus-pituitary communication. Furthermore, neonatal thymulin gene therapy has been shown to pre...

journal_title：Histology and histopathology

authors： Martines E,Reggiani PC,Schwerdt JI,Goya RG,Cónsole G

更新日期：2011-04-01 00:00:00

abstract：:Recent studies have shown that papillary renal cell carcinoma (RCC) is clinically and genotypically a distinct entity. Papillary RCCs account for about 10-15% of renal parenchymal neoplasms. Macroscopically, the cut surface is yellow or brown in color and large tumors frequently show cystic change. Hemorrhage and necr...

journal_title：Histology and histopathology

authors： Kuroda N,Toi M,Hiroi M,Enzan H

更新日期：2003-04-01 00:00:00

abstract：INTRODUCTION:It is difficult to prevent and treat intra- and peri-neural fibrosis after peripheral nerve surgery. Many authors have attempted to develop and verify the effectiveness of substances to decrease the formation of adherences in different tissues. MATERIAL AND METHODS:this study aimed to assess the effective...

journal_title：Histology and histopathology

authors： Hernández-Cortés P,Peregrina M,Aneiros-Fernández J,Tassi M,Pajares-López M,Toledo M,O'Valle F

更新日期：2010-06-01 00:00:00

abstract：:The reactivity of endothelial cells to putative endothelial cell-specific markers varies with species, with vessel size and with the organ studied. To determine their value in studies of fetal rat lung, and whether organ immaturity would also influence reactivity, we studied endothelial cell immunoreactivity to antibo...

journal_title：Histology and histopathology

authors： Han RN,Tanswell AK,Post M

更新日期：1992-10-01 00:00:00

abstract：:The need for an immunophenotypical referential framework relative to lymphoid follicle has led us to apply a panel of monoclonal and polyclonal antibodies, by means of a sensitive immunostaining method. Lymphoid follicle is an immunophenotypically complex structure made up of three lymphoid populations (B, being its b...

journal_title：Histology and histopathology

authors： de Luaces CP,Peral JI,García Tejeiro M,Aguirre C

更新日期：1988-01-01 00:00:00

abstract：:Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for the purpose of anti-inflammation, antipyretic, and analgesia. For this aim, they are used for the alleviation of pain, fever, and inflammation associated with rheumatoid arthritis, sports injuries, and temporary pain. However, treatment with NSAIDs may ...

journal_title：Histology and histopathology

authors： Aygün D,Kaplan S,Odaci E,Onger ME,Altunkaynak ME

更新日期：2012-04-01 00:00:00

abstract：:Junctional complexes such as tight junctions, adherens junctions, and desmosomes play crucial roles in the structure and function of epithelial cells. These junctions are involved in increasing cell-cell contact and as well serve as signaling centers regulating multiple functions in epithelial cells. Carcinoma cell li...

journal_title：Histology and histopathology

authors： Kim G,Rajasekaran SA,Thomas G,Rosen EA,Landaw EM,Shintaku P,Lassman C,Said J,Rajasekaran AK

更新日期：2005-01-01 00:00:00

abstract：:Cerebral cavernous malformations (CCMs) are described as vascular lesions consisting of endothelial-lined dilated vessels embedded in a connective tissue sheath without intervening parenchyma between them. Their anatomical connections with the normal blood vessels are still enigmatic and the fine three-dimensional (3-...

journal_title：Histology and histopathology

authors： Toralba S,Landemore G,Coquemont M,Plancoulaine B,Chapon F

更新日期：2014-08-01 00:00:00

abstract：AIMS:Gastric hyperplastic polyps (GHPs) are the most common polypoid lesion of the stomach, and their malignant potential has been demonstrated. In the present study, we evaluated the mucin phenotypes of GHPs and investigated the relationships among mucin phenotypes and clinical-pathological factors, proliferative acti...

journal_title：Histology and histopathology

authors： Li J,Wu LH,Shi Y,Li HM,Song MY,Jiao YF

更新日期：2014-03-01 00:00:00

abstract：:Aurora A and Aurora B are serine-threonine kinase proteins which have both been implicated in human carcinogenesis through development of aneuploidy and chromosomal instability. The aim of the study is to assess the correlation of both markers with clinical and pathological parameters in patients with bladder cancer o...

journal_title：Histology and histopathology

authors： Bufo P,Sanguedolce F,Tortorella S,Cormio L,Carrieri G,Pannone G

更新日期：2010-11-01 00:00:00

abstract：:Epidermal proliferation, inflammatory changes and microvascular augmentation are prominent features of chronic cutaneous psoriatic lesions. The objective of this study was the investigation of blood and lymphatic microvascular changes in relation to epidermal changes and inflammatory infiltration in dermis. Immunohist...

journal_title：Histology and histopathology

authors： Výbohová D,Adamicová K,Mellová Y,Hešková G

更新日期：2017-05-01 00:00:00

abstract：:Chorioamnionitis and preeclampsia account for the majority of preterm births worldwide. Thus far, adequate methods for early detection or prevention of these diseases are lacking. In preeclampsia, accelerated villous maturation is believed to compensate placental insufficiency. However, little is known about the effec...

journal_title：Histology and histopathology

authors： Vangrieken P,Vanterpool SF,van Schooten FJ,Al-Nasiry S,Andriessen P,Degreef E,Alfer J,Kramer BW,von Rango U

更新日期：2020-08-01 00:00:00

abstract：:Shotgun pellets containing bismuth (Bi) are widely used and may cause a rather intense exposure of some wild animals to Bi. A Bi shotgun pellet was implanted intramuscularly in the triceps surae muscle of 18 adult male Wistar rats. Another group of 9 animals had a Bi shotgun pellet implanted intracranially in the neoc...

journal_title：Histology and histopathology

authors： Stoltenberg M,Locht L,Larsen A,Jensen D,Danscher G

更新日期：2003-07-01 00:00:00

abstract：:Cyclosporin A is an immunosuppressive drug, which disrupts the activation of peripheral T-lymphocyte pool and blocks the maturation of thymocytes within the thymus. Normally, thymic nonlymphoid cells provide the optimal inductive microenvironment for development of T-lymphocytes. After application of cyclosporin A the...

journal_title：Histology and histopathology

authors： Milićević NM,Milićević Z

更新日期：1998-10-01 00:00:00

abstract：:Sphingosine kinase functions to phosphorylate sphingosine to sphingosine 1-phosphate (S1P) to keep balance in the metabolites of sphingolipids. There are two isoforms of sphingosine kinase, sphingosine kinase 1 (SphK1) and sphingosine kinase 2 (SphK2). Although SphK1 and SphK2 share high sequence similarity, SphK2 has...

journal_title：Histology and histopathology

authors： Song DD,Zhou JH,Sheng R

更新日期：2018-05-01 00:00:00

abstract：:Detailed histomorphometric analysis of human conjunctival biopsy specimens has convincingly demonstrated that tissue remodeling of the extracellular matrix (ECM) is an essential and dynamic process associated with conjunctival scarring in ocular cicatricial pemphigoid (OCP). The conjunctival scarring often eventually ...

journal_title：Histology and histopathology

authors： Razzaque MS,Foster CS,Ahmed AR

更新日期：2001-10-01 00:00:00