Immunohistochemical expression and localization of MMP-9, MMP-13, E-Cadherin and Ki-67 in road pavers' skin chronically exposed to bitumen products.

abstract：:The FHIT gene encompassing the most active common human fragile region, FRA3B, has been proposed as a tumour suppressor gene for important common human carcinomas. The mechanism in which Fhit protein exerts its tumour suppressor activity is still obscure. To further understand the Fhit function associated with its int...

journal_title：Histology and histopathology

authors： Zhao P,Hou N,Lu Y

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:The Shwachman-Bodian-Diamond syndrome (SBDS) protein is a member of a highly conserved family which influences RNA activation and is associated with pancreatic, skeletal and bone marrow deficiencies, as well as hematological malignancies. METHODS:In this study, the expression and localization of SBDS were i...

journal_title：Histology and histopathology

authors： Kayed H,Bekasi S,Keleg S,Welsch T,Esposito I,Shimamura A,Michalski CW,Friess H,Kleeff J

更新日期：2008-07-01 00:00:00

abstract：:The three-dimensional structure of the pancreatic ductular system (from the intercalated duct to the intercellular secretory canaliculus) is controversial and unclear. The aim of this study is to reveal the three-dimensional structure of the pancreatic ductular sysytem at the onset of pancreatitis. One day following r...

journal_title：Histology and histopathology

authors： Endo H,Ashizawa N,Niigaki M,Hamamoto N,Niigaki M,Kaji T,Katsube T,Watanabe M,Naora H,Otani H,Kinoshita Y

更新日期：2002-01-01 00:00:00

abstract：:We wanted to examine the effect of antigen retrieval on epoxy sections where the tissue had been infiltrated by resin containing moderately increased amounts of accelerator. The concentration of accelerator DMP-30 (Tri(Dimethyl Amino Methyl) Phenol) was varied in the range of 0% to 4% in the infiltration step of the t...

journal_title：Histology and histopathology

authors： Brorson SH,Andersen T,Haug S,Kristiansen I,Risstubben A,Tchou H,Ulstein J

更新日期：1999-01-01 00:00:00

abstract：:Experimental Doxorubicin-exposure in utero is correlated with foetal oesophageal atresia, tracheo-oesophageal fistula, axial alterations. While gastrointestinal and respiratory defects have been largely investigated, only sporadic data have been published to date on notochordal and vertebral defects. The aim of this w...

journal_title：Histology and histopathology

authors： Menegola E,Broccia ML,Di RF

更新日期：2002-01-01 00:00:00

abstract：:Circadian and seasonal variations were observed in the karyometric index of pinealocytes in the cortical and medullary regions of the distal pineal body. The study involved 70 Wistar rats over a 24-hour interval (0:6, 10:00, 14:00, 18:00, 22:00, 02:00, 06:00 h) during two natural photoluminous periods, i.e. late summe...

journal_title：Histology and histopathology

authors： Cimas García C,Martínez Soriano F,Ruiz Torner A

更新日期：1992-10-01 00:00:00

abstract：:Much effort has been made by researchers to elucidate the complex biology of breast cancer stem cells (BCSCs), a small subset of breast tumor cells that display stem cell properties, drive tumor initiation, and growth. In recent years, it has been suggested that BCSCs could be responsible for the process of metastasis...

journal_title：Histology and histopathology

authors： Schwarz-Cruz Y Celis A,Espinosa M,Maldonado V,Melendez-Zajgla J

更新日期：2016-06-01 00:00:00

abstract：:The ultrastructure of four aldosterone secreting adenomas and of the adjacent zona glomerulosa has been described by the use of stereological techniques. Adenomatous cells (about 2800 microns 3 in volume) invariably displayed a striking abundance of lipid droplets, which occupied about 30% of the cytoplasm. Mitochondr...

journal_title：Histology and histopathology

authors： Belloni AS,Mantero F,Rocco S,Gottardo G,Mazzocchi G,Nussdorfer GG

更新日期：1988-07-01 00:00:00

abstract：:The importance of molybdenum-containing enzymes in the pathophysiology of a number of clinical disorders necessitates a comprehensive understanding of their histological localization and expression. The objectives of this review are to cover such enzymes so far reported and their enzyme- and immunohistochemical locali...

journal_title：Histology and histopathology

authors： Moriwaki Y,Yamamoto T,Higashino K

更新日期：1997-04-01 00:00:00

abstract：:The aim of the study was to estimate the significance of oxidative/nitrosative damage and expression of antioxidant enzymes in renal cell carcinomas (RCC). For this we investigated immunohistochemically six antioxidant enzymes (AOEs) including MnSOD, ECSOD, thioredoxin, thioredoxin reductase, and gammaglutamyl cystein...

journal_title：Histology and histopathology

authors： Soini Y,Kallio JP,Hirvikoski P,Helin H,Kellokumpu-Lehtinen P,Tammela TL,Peltoniemi M,Martikainen PM,Kinnula LV

更新日期：2006-02-01 00:00:00

abstract：:Ebulin f is a ribosome-inactivating protein (RIP) present in green fruits of the dwarf elder (Sambucus ebulus L). Since dwarf elder fruits are used for food and as a medicine, we assessed the study of toxicological effects and safety of ebulin f in elderly mice, comparing these results with those reported in young ani...

journal_title：Histology and histopathology

authors： Garrosa M,Jiménez P,Córdoba-Díaz D,García-Recio V,Gayoso S,Rojo MÁ,Gayoso MJ,Girbés T

更新日期：2018-09-01 00:00:00

abstract：:Our previous study on human skeletal muscle undergoing ischemia and reperfusion has revealed that granulocytes, which infiltrate the muscle tissue in large numbers, play an important role in mediating fibre injuries by producing superoxide anion (O2-) which is responsible for membrane lipid peroxidation. In the curren...

journal_title：Histology and histopathology

authors： Adembri C,Domenici LL,Formigli L,Brunelleschi S,Ferrari E,Novelli GP

更新日期：1994-10-01 00:00:00

abstract：:The ultrastructure of the atrial myocardium in the monkey (Macaca fascicularis) was studied after bilateral cervical vagotomy and survival times of 100, 175 and 367 days. Changes were observed in the nucleus and the cytoplasm of the myocyte. Sequestered within the nuclei of the affected myocytes were cytoplasmic organ...

journal_title：Histology and histopathology

authors： Wong WC,Yick TY,Ling EA

更新日期：1989-07-01 00:00:00

abstract：:Epidermal proliferation, inflammatory changes and microvascular augmentation are prominent features of chronic cutaneous psoriatic lesions. The objective of this study was the investigation of blood and lymphatic microvascular changes in relation to epidermal changes and inflammatory infiltration in dermis. Immunohist...

journal_title：Histology and histopathology

authors： Výbohová D,Adamicová K,Mellová Y,Hešková G

更新日期：2017-05-01 00:00:00

abstract：:Versican, a large extracellular matrix proteoglycan accumulates in tumor stroma and plays a key role in both malignant transformation and tumor progression. Increased versican expression has been observed in a wide range of malignant tumors, and has been associated with both cancer relapse and poor patient outcomes in...

journal_title：Histology and histopathology

authors： Du WW,Yang W,Yee AJ

更新日期：2013-06-01 00:00:00

abstract：:One hundred and eleven pituitary glands of patients (93 males, 18 females; mean age 32 years, 5 months) who died of fully developed AIDS or ARC were examined under light microscopy with the aid of immunohistochemistry. On post mortem (p.m.) examination a wide series of multiorgan alterations was noticed. Microscopical...

journal_title：Histology and histopathology

authors： Mosca L,Costanzi G,Antonacci C,Boldorini R,Carboni N,Cristina S,Liverani C,Parravicini C,Pirolo A,Vago L

更新日期：1992-04-01 00:00:00

abstract：:Cell secretion is an important physiological process that ensures smooth metabolic activities, tissue repair and growth and immunological functions in the body. It occurs when the intracellular secretory materials are released to the exterior; these may be in the form of lipids, protein or mucous and may travel throug...

journal_title：Histology and histopathology

authors： Gesase AP,Satoh Y

更新日期：2003-04-01 00:00:00

abstract：:The proto-oncogene, ets-1, is a transcription factor known to control the expression of a number of genes and has been postulated to play a role in cell growth, differentiation and tumour invasion. We examined 137 cases of breast carcinoma by immunohistochemistry and compared the degree of Ets-1 expression among the d...

journal_title：Histology and histopathology

authors： Katayama S,Nakayama T,Ito M,Naito S,Sekine I

更新日期：2005-01-01 00:00:00

abstract：:The response of the SON to various forms of stress is well documented. However, the effect of operative stress, which is a common and important clinical event requiring the mediation of vasopressin, has largely escaped attention. The present report describes the ultrastructural changes in the neurons of the caudal (re...

journal_title：Histology and histopathology

authors： Ray PK,Choudhury SR

更新日期：1988-04-01 00:00:00

abstract：:The sarcolemmal domain of rat duodenal smooth muscle cells includes caveolae and associated cytoskeletal or filamentous elements. We have used the quick-freezing, deep-etching method to examine the three dimensional relationships between these components. Replica membranes for separated strips of rat duodenal muscle l...

journal_title：Histology and histopathology

authors： Takayama I,Fujii Y,Terada N,Baba T,Kato Y,Fujino MA,Ohno S

更新日期：2000-10-01 00:00:00

abstract：:The present review examines various aspects of the developmental expression of neuropeptides and of their receptors in mammalian retinas, emphasizing their possible roles in retinal maturation. Different peptidergic systems have been investigated with some detail during retinal development, including substance P (SP),...

journal_title：Histology and histopathology

authors： Bagnoli P,Dal Monte M,Casini G

更新日期：2003-10-01 00:00:00

abstract：:Representative tumour sections from 468 patients with invasive breast cancer were immunostained for cyclooxygenase-2 (COX-2) and evaluated. The relationships between COX-2 expression, clinical outcome and various clinicopathological variables, including tumour vascularity and disseminated tumour cells (DTC) in the bon...

journal_title：Histology and histopathology

authors： Dhakal HP,Naume B,Synnestvedt M,Borgen E,Kaaresen R,Schlichting E,Wiedswang G,Bassarova A,Holm R,Giercksky KE,Nesland JM

更新日期：2012-10-01 00:00:00

abstract：:Immunohistochemistry of the terminal complement complex (C5b-9) and fibronectin (FN) is useful to detect myocardial ischemia preceding necrosis in the postmortem diagnosis of sudden cardiac death. The present immunohistochemical study examined connexin43 (Cx43) and zonula occludens-1 (ZO-1) as markers of early myocard...

journal_title：Histology and histopathology

authors： Kawamoto O,Michiue T,Ishikawa T,Maeda H

更新日期：2014-06-01 00:00:00

abstract：:The influence of He-Ne laser radiation on the formation of new blood vessels in the bone marrow compartment of a regenerating area of the mid-cortical diaphysis of the tibiae of young adult rats was studied. A small hole was surgically made with a dentistry burr in the tibia and the injured area received a daily laser...

journal_title：Histology and histopathology

authors： Garavello I,Baranauskas V,da Cruz-Höfling MA

更新日期：2004-01-01 00:00:00

abstract：:The renin-angiotensin system (RAS) and tubuloglomerular feedback (TGF) are central to the maintenance of blood pressure and body fluid composition. Renin, NO synthase-1 (NOS-1), and cyclooxygenase-2 (COX-2) are key regulators of the RAS and TGF. In the present study, to investigate species-specific differences in the ...

journal_title：Histology and histopathology

authors： Ichii O,Yabuki A,Ojima T,Matsumoto M,Taniguchi K,Suzuki S

更新日期：2008-02-01 00:00:00

abstract：:The main role of growth arrest and DNA damage-inducible (GADD) genes is to block proliferation at G1 and G2 checkpoints in response to DNA damage. The goal of this study was to examine the expression of GADD genes in primary melanomas with respect to prognosis. GADD34 was found in 73% of the primary melanomas investig...

journal_title：Histology and histopathology

authors： Korabiowska M,Cordon-Cardo C,Betke H,Schlott T,Kotthaus M,Stachura J,Brinck U

更新日期：2002-01-01 00:00:00

abstract：:The adrenal glands of lower vertebrates display a notable intermingling between steroidogenic and chromaffin tissues, which increases from Pisces to Aves. As in mammals, adrenal chromaffin cells contain and release, in addition to catecholamines, serotonin and several peptides, which may affect the secretory activity ...

journal_title：Histology and histopathology

authors： Mazzocchi G,Gottardo G,Nussdorfer GG

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Honey and olive oil are natural products that have high nutritional values, and therapeutic properties. Cytotoxic drugs, like methotrexate (MTX) are used to treat malignancies in tumour cells; however, these drugs also have serious side effects that could threaten the patient's life. AIM:To evaluate the pot...

journal_title：Histology and histopathology

authors： Alturkistani HA,Abuzinadah OAH,Kelany AM,Abd El-Aziz GS,Alrafiah AR

更新日期：2019-12-01 00:00:00

abstract：:In the present study we examined prognostic value of immunohistochemical estimation of topoisomerase 1A (TOP 1A) and HER-2/neu expression in ovarian cancers treated with platinum-based drugs but not with topotecan and the relation between expression of these proteins on the one hand and intensity of proliferation (Ki6...

journal_title：Histology and histopathology

authors： Surowiak P,Materna V,Kaplenko I,Spaczynski M,Dietel M,Lage H,Zabel M

更新日期：2006-07-01 00:00:00

abstract：:Autophagy and apoptosis are two important molecular mechanisms that maintain cellular homeostasis under stress conditions. Autophagy represents an intracellular mechanism responsible for turnover of organelles and long-lived proteins through a lysosome-dependent degradation pathway. Cell death signals or sustained str...

journal_title：Histology and histopathology

authors： Oral O,Akkoc Y,Bayraktar O,Gozuacik D

更新日期：2016-05-01 00:00:00